JP2002538224A - 脂肪酸−抗癌剤複合体およびこの使用 - Google Patents

脂肪酸−抗癌剤複合体およびこの使用

Info

Publication number
JP2002538224A
JP2002538224A JP2000603720A JP2000603720A JP2002538224A JP 2002538224 A JP2002538224 A JP 2002538224A JP 2000603720 A JP2000603720 A JP 2000603720A JP 2000603720 A JP2000603720 A JP 2000603720A JP 2002538224 A JP2002538224 A JP 2002538224A
Authority
JP
Japan
Prior art keywords
fatty acid
acid
taxane
complex
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000603720A
Other languages
English (en)
Japanese (ja)
Inventor
エル． ウェッブ，ニゲル
オー． ブラッドレー，マシューズ
アンソニー，フォレスト
フィッシャー，マーク
Original Assignee
プロタルガ，インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/265,307 external-priority patent/US7235583B1/en
Application filed by プロタルガ，インコーポレーテッド filed Critical プロタルガ，インコーポレーテッド
Publication of JP2002538224A publication Critical patent/JP2002538224A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000603720A 1999-03-09 2000-03-09 脂肪酸−抗癌剤複合体およびこの使用 Pending JP2002538224A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/265,307 US7235583B1 (en) 1999-03-09 1999-03-09 Fatty acid-anticancer conjugates and uses thereof
US18615200P 2000-03-01 2000-03-01
US09/265,307 2000-03-01
US60/186,152 2000-03-01
PCT/US2000/006160 WO2000053231A2 (fr) 1999-03-09 2000-03-09 Conjugues d'acides gras et d'agents anticancereux, et utilisations correspondantes

Publications (1)

Publication Number Publication Date
JP2002538224A true JP2002538224A (ja) 2002-11-12

Family

ID=26881822

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000603720A Pending JP2002538224A (ja) 1999-03-09 2000-03-09 脂肪酸−抗癌剤複合体およびこの使用

Country Status (10)

Country Link
EP (1) EP1163011A2 (fr)
JP (1) JP2002538224A (fr)
KR (1) KR20020000147A (fr)
CN (1) CN1377282A (fr)
AU (1) AU3733300A (fr)
CA (1) CA2366723C (fr)
CZ (1) CZ20013123A3 (fr)
HK (1) HK1040486A1 (fr)
RU (1) RU2001127313A (fr)
WO (1) WO2000053231A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006098241A1 (fr) * 2005-03-14 2006-09-21 Otsuka Pharmaceutical Factory, Inc. Composition pharmaceutique contenant un médicament à peine soluble dans l'eau
JP2015527314A (ja) * 2012-07-10 2015-09-17 ベースクリック ゲーエムベーハー アナンダミド−修飾核酸分子

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994392A (en) * 1988-02-26 1999-11-30 Neuromedica, Inc. Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid
US8552054B2 (en) * 2001-03-23 2013-10-08 Luitpold Pharmaceuticals, Inc. Fatty amine drug conjugates
JP4634694B2 (ja) * 2001-03-23 2011-02-16 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪アルコール薬物複合体
US7169752B2 (en) 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
PT1509256E (pt) 2002-05-24 2009-10-15 Angiotech Int Ag Composições e métodos de revestimento de implantes médicos
CA2529125A1 (fr) 2003-06-19 2004-12-23 Yeda Research & Development Co. Ltd. Lipopeptides antimicrobiens et anticancereux
CA2544128A1 (fr) * 2003-10-30 2005-05-12 The Research Foundation Of State University Of New York Conjugues taxoide/acide gras et preparations les contenant
KR100753112B1 (ko) * 2007-02-26 2007-08-29 (주)고려다이나믹스 카드 발권 시스템
CN117088935A (zh) * 2022-05-20 2023-11-21 上海维洱生物医药科技有限公司 一种雷公藤甲素木蜡酸酯及其脂质体与制备方法
KR20230174082A (ko) * 2022-06-20 2023-12-27 (주) 바이오인프라생명과학 약물을 전달하기 위한 초음파 감응형 약물전달체를 생성하는 방법 및 이를 이용한 초음파 감응형 약물전달체
WO2024110843A1 (fr) 2022-11-21 2024-05-30 Segena Corporation S.A. Amélioration de l'activité immunomodulatrice d'oligonucléotides par modification de longue durée de dianophore : procédés et applications
CN116676355B (zh) * 2023-08-03 2023-10-24 成都第一制药有限公司 一种催化合成山莨菪碱的方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法
WO1997044336A1 (fr) * 1996-05-22 1997-11-27 Neuromedica, Inc. Conjugues d'acide cis-docosahexaenoique et de paclitaxel
WO1997044026A1 (fr) * 1996-05-22 1997-11-27 Neuromedica, Inc. Compositions contenant des conjugues d'acide cis-docosahexanoique et de taxotere
WO1997044063A2 (fr) * 1996-05-22 1997-11-27 Neuromedica, Inc. Conjugues d'acide cis-docosahexanoïque et d'agents pharmaceutiques

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011668A1 (fr) * 1991-12-10 1993-06-24 Rush-Presbyterian-St. Luke's Medical Center Procedes et compositions destines a reduire la multiresistance aux medicaments
US5925669A (en) * 1994-03-22 1999-07-20 Molecular/Structural Bio Technologies, Inc. Carrier compositions for anti-neoplastic drugs
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US6136988A (en) * 1998-04-10 2000-10-24 Hauser, Inc. 7-hexanoyltaxol and methods for preparing the same

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法
WO1997044336A1 (fr) * 1996-05-22 1997-11-27 Neuromedica, Inc. Conjugues d'acide cis-docosahexaenoique et de paclitaxel
WO1997044026A1 (fr) * 1996-05-22 1997-11-27 Neuromedica, Inc. Compositions contenant des conjugues d'acide cis-docosahexanoique et de taxotere
WO1997044063A2 (fr) * 1996-05-22 1997-11-27 Neuromedica, Inc. Conjugues d'acide cis-docosahexanoïque et d'agents pharmaceutiques
JP2000511188A (ja) * 1996-05-22 2000-08-29 ニューロメディカ インコーポレーテッド シス―ドコサヘキサエン酸とｔａｘ―その他との共有複合体を含有する製剤
JP2000511187A (ja) * 1996-05-22 2000-08-29 ニューロメディカ インコーポレーテッド シス―ドコサヘキサエン酸およびパクリタクセルの複合体
JP2000514405A (ja) * 1996-05-22 2000-10-31 プロタルガ インコーポレーテッド Ｄｈａ―薬剤複合体

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006098241A1 (fr) * 2005-03-14 2006-09-21 Otsuka Pharmaceutical Factory, Inc. Composition pharmaceutique contenant un médicament à peine soluble dans l'eau
JP4929158B2 (ja) * 2005-03-14 2012-05-09 株式会社大塚製薬工場 難水溶性薬物を含有する医薬組成物
KR101391020B1 (ko) * 2005-03-14 2014-04-30 가부시키가이샤 오츠까 세이야꾸 고죠 수난용성 약제를 함유한 약학 조성물
JP2015527314A (ja) * 2012-07-10 2015-09-17 ベースクリック ゲーエムベーハー アナンダミド−修飾核酸分子

Also Published As

Publication number Publication date
KR20020000147A (ko) 2002-01-04
EP1163011A2 (fr) 2001-12-19
CN1377282A (zh) 2002-10-30
WO2000053231A3 (fr) 2001-10-04
CA2366723A1 (fr) 2000-09-14
RU2001127313A (ru) 2003-09-20
CZ20013123A3 (cs) 2002-03-13
CA2366723C (fr) 2011-08-02
WO2000053231A2 (fr) 2000-09-14
AU3733300A (en) 2000-09-28
HK1040486A1 (zh) 2002-06-14

Similar Documents

Publication Publication Date Title
JP4172725B2 (ja) シス―ドコサヘキサエン酸およびパクリタクセルの複合体
JP4634694B2 (ja) 脂肪アルコール薬物複合体
JP7381684B2 (ja) 遊離可能コンジュゲート
JP2005500988A (ja) 脂肪族アミン薬物複合体
JP4172726B2 (ja) シス―ドコサヘキサエン酸とドセタキセルとの共有複合体を含有する製剤
US20080125380A1 (en) Fatty acid-anticancer conjugates and uses thereof
JP2002538224A (ja) 脂肪酸−抗癌剤複合体およびこの使用
ES2222514T3 (es) Conjugados de dha y agentes farmaceuticos.
ES2244098T3 (es) Un conjugado covalente de clozapina con un acido graso y su uso para tratar la esquizofrenia.
WO1997044336A9 (fr) Conjugues d'acide cis-docosahexaenoique et de paclitaxel
JP2004514650A (ja) デヒドロアスコルビン酸処方物およびその使用
WO2000067802A1 (fr) Compositions d'acides gras -n-substituted indol-3-glyoxyl-amide et leur utilisation
ES2965383T3 (es) Polímero y composición a partir de una fuente renovable
JP2023538695A (ja) 薬剤を担持する高分子及びその調製方法
AU2008203341A1 (en) Fatty acid-anticancer conjugates and uses thereof
AU2005201503A1 (en) Fatty acid-anticancer conjugates and uses thereof
AU722912C (en) Compositions comprising conjugates of cis-docosahexaenoic acid and docetaxel

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20040812

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070308

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100810

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20101105

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101112

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20101208

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101215

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110412