CN1377282A - 脂肪酸-抗癌缀合物及其应用 - Google Patents
脂肪酸-抗癌缀合物及其应用 Download PDFInfo
- Publication number
- CN1377282A CN1377282A CN00804762A CN00804762A CN1377282A CN 1377282 A CN1377282 A CN 1377282A CN 00804762 A CN00804762 A CN 00804762A CN 00804762 A CN00804762 A CN 00804762A CN 1377282 A CN1377282 A CN 1377282A
- Authority
- CN
- China
- Prior art keywords
- fatty acid
- acid
- taxane
- conjugate
- anticancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/265,307 | 1999-03-09 | ||
US09/265,307 US7235583B1 (en) | 1999-03-09 | 1999-03-09 | Fatty acid-anticancer conjugates and uses thereof |
US18615200P | 2000-03-01 | 2000-03-01 | |
US60/186,152 | 2000-03-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1377282A true CN1377282A (zh) | 2002-10-30 |
Family
ID=26881822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN00804762A Pending CN1377282A (zh) | 1999-03-09 | 2000-03-09 | 脂肪酸-抗癌缀合物及其应用 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1163011A2 (fr) |
JP (1) | JP2002538224A (fr) |
KR (1) | KR20020000147A (fr) |
CN (1) | CN1377282A (fr) |
AU (1) | AU3733300A (fr) |
CA (1) | CA2366723C (fr) |
CZ (1) | CZ20013123A3 (fr) |
HK (1) | HK1040486A1 (fr) |
RU (1) | RU2001127313A (fr) |
WO (1) | WO2000053231A2 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101137395B (zh) * | 2005-03-14 | 2012-10-31 | 株式会社大塚制药工场 | 含有水难溶性药物的医药组合物 |
WO2023221961A1 (fr) * | 2022-05-20 | 2023-11-23 | 上海维洱生物医药科技有限公司 | Lignocérate de triptolide, liposome de celui-ci et procédé de préparation associé |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5994392A (en) * | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
US7816398B2 (en) * | 2001-03-23 | 2010-10-19 | Luitpold Pharmaceuticals, Inc. | Fatty alcohol drug conjugates |
JP2005500988A (ja) * | 2001-03-23 | 2005-01-13 | ルイトポルド・ファーマシューティカルズ・インコーポレーテッド | 脂肪族アミン薬物複合体 |
US7169752B2 (en) | 2003-09-30 | 2007-01-30 | New River Pharmaceuticals Inc. | Compounds and compositions for prevention of overdose of oxycodone |
CN100341589C (zh) | 2002-05-24 | 2007-10-10 | 血管技术国际股份公司 | 用于涂覆医用植入物的组合物和方法 |
CA2529125A1 (fr) | 2003-06-19 | 2004-12-23 | Yeda Research & Development Co. Ltd. | Lipopeptides antimicrobiens et anticancereux |
EP1703904B1 (fr) * | 2003-10-30 | 2013-02-13 | The Research Foundation of the State University of New York | Conjugues taxoide/acide gras et preparations les contenant |
KR100753112B1 (ko) * | 2007-02-26 | 2007-08-29 | (주)고려다이나믹스 | 카드 발권 시스템 |
AU2013288738A1 (en) * | 2012-07-10 | 2015-01-29 | Baseclick Gmbh | Anandamide-modified nucleic acid molecules |
KR20230174082A (ko) * | 2022-06-20 | 2023-12-27 | (주) 바이오인프라생명과학 | 약물을 전달하기 위한 초음파 감응형 약물전달체를 생성하는 방법 및 이를 이용한 초음파 감응형 약물전달체 |
CN116676355B (zh) * | 2023-08-03 | 2023-10-24 | 成都第一制药有限公司 | 一种催化合成山莨菪碱的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5925327A (ja) * | 1982-07-31 | 1984-02-09 | Hidematsu Hirai | 抗腫瘍性複合体の製造方法 |
AU3243393A (en) * | 1991-12-10 | 1993-07-19 | Rush - Presbyterian - St. Luke's Medical Center | Methods and compositions for reducing multi-drug resistance |
US5925669A (en) * | 1994-03-22 | 1999-07-20 | Molecular/Structural Bio Technologies, Inc. | Carrier compositions for anti-neoplastic drugs |
US5580899A (en) * | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
JP4172726B2 (ja) * | 1996-05-22 | 2008-10-29 | ルイトポルド・ファーマシューティカルズ・インコーポレーテッド | シス―ドコサヘキサエン酸とドセタキセルとの共有複合体を含有する製剤 |
US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
US6136988A (en) * | 1998-04-10 | 2000-10-24 | Hauser, Inc. | 7-hexanoyltaxol and methods for preparing the same |
-
2000
- 2000-03-09 WO PCT/US2000/006160 patent/WO2000053231A2/fr not_active Application Discontinuation
- 2000-03-09 KR KR1020017011387A patent/KR20020000147A/ko not_active Application Discontinuation
- 2000-03-09 CN CN00804762A patent/CN1377282A/zh active Pending
- 2000-03-09 CZ CZ20013123A patent/CZ20013123A3/cs unknown
- 2000-03-09 EP EP00916188A patent/EP1163011A2/fr not_active Withdrawn
- 2000-03-09 JP JP2000603720A patent/JP2002538224A/ja active Pending
- 2000-03-09 CA CA2366723A patent/CA2366723C/fr not_active Expired - Fee Related
- 2000-03-09 RU RU2001127313/14A patent/RU2001127313A/ru not_active Application Discontinuation
- 2000-03-09 AU AU37333/00A patent/AU3733300A/en not_active Abandoned
-
2002
- 2002-01-28 HK HK02100653.6A patent/HK1040486A1/zh unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101137395B (zh) * | 2005-03-14 | 2012-10-31 | 株式会社大塚制药工场 | 含有水难溶性药物的医药组合物 |
WO2023221961A1 (fr) * | 2022-05-20 | 2023-11-23 | 上海维洱生物医药科技有限公司 | Lignocérate de triptolide, liposome de celui-ci et procédé de préparation associé |
Also Published As
Publication number | Publication date |
---|---|
RU2001127313A (ru) | 2003-09-20 |
CZ20013123A3 (cs) | 2002-03-13 |
AU3733300A (en) | 2000-09-28 |
WO2000053231A2 (fr) | 2000-09-14 |
JP2002538224A (ja) | 2002-11-12 |
HK1040486A1 (zh) | 2002-06-14 |
KR20020000147A (ko) | 2002-01-04 |
CA2366723C (fr) | 2011-08-02 |
CA2366723A1 (fr) | 2000-09-14 |
WO2000053231A3 (fr) | 2001-10-04 |
EP1163011A2 (fr) | 2001-12-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7816398B2 (en) | Fatty alcohol drug conjugates | |
US8552054B2 (en) | Fatty amine drug conjugates | |
US6576636B2 (en) | Method of treating a liver disorder with fatty acid-antiviral agent conjugates | |
AU725759B2 (en) | DHA-pharmaceutical agent conjugates | |
JP5421340B2 (ja) | 癌治療のためのアジア酸またはアジアチコサイドの使用。 | |
US20080125380A1 (en) | Fatty acid-anticancer conjugates and uses thereof | |
CN1377282A (zh) | 脂肪酸-抗癌缀合物及其应用 | |
US8349832B2 (en) | Compounds and compositions for treating cancer | |
US8318737B2 (en) | Compounds and compositions for treating cancer | |
WO2000067802A1 (fr) | Compositions d'acides gras -n-substituted indol-3-glyoxyl-amide et leur utilisation | |
EP2473506A2 (fr) | Composés et compositions pour le traitement du cancer | |
AU2008203341A1 (en) | Fatty acid-anticancer conjugates and uses thereof | |
AU2005201503A1 (en) | Fatty acid-anticancer conjugates and uses thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: LOUTBLEDE PHARMACEUTICALS CO., LTD. Free format text: FORMER OWNER: PROTARGA INC. Effective date: 20060310 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20060310 Address after: American New York Applicant after: Root Bolide Pharmaceutical Co. Ltd. Address before: American Pennsylvania Applicant before: Protarga Inc. |