CA2366723C - Conjugues d'acides gras et d'agents anticancereux, et utilisations correspondantes - Google Patents
Conjugues d'acides gras et d'agents anticancereux, et utilisations correspondantes Download PDFInfo
- Publication number
- CA2366723C CA2366723C CA2366723A CA2366723A CA2366723C CA 2366723 C CA2366723 C CA 2366723C CA 2366723 A CA2366723 A CA 2366723A CA 2366723 A CA2366723 A CA 2366723A CA 2366723 C CA2366723 C CA 2366723C
- Authority
- CA
- Canada
- Prior art keywords
- fatty acid
- anticancer compound
- conjugate
- taxane
- mtd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention concerne des conjugués d'acides gras et d'agents anticancéreux utilisés dans le traitement du cancer, ainsi que des compositions et des formulations renfermant ces conjugués. L'invention concerne également des méthodes d'utilisation desdits conjugués.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/265,307 US7235583B1 (en) | 1999-03-09 | 1999-03-09 | Fatty acid-anticancer conjugates and uses thereof |
US18615200P | 2000-03-01 | 2000-03-01 | |
US09/265,307 | 2000-03-01 | ||
US60/186,152 | 2000-03-01 | ||
PCT/US2000/006160 WO2000053231A2 (fr) | 1999-03-09 | 2000-03-09 | Conjugues d'acides gras et d'agents anticancereux, et utilisations correspondantes |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2366723A1 CA2366723A1 (fr) | 2000-09-14 |
CA2366723C true CA2366723C (fr) | 2011-08-02 |
Family
ID=26881822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2366723A Expired - Fee Related CA2366723C (fr) | 1999-03-09 | 2000-03-09 | Conjugues d'acides gras et d'agents anticancereux, et utilisations correspondantes |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1163011A2 (fr) |
JP (1) | JP2002538224A (fr) |
KR (1) | KR20020000147A (fr) |
CN (1) | CN1377282A (fr) |
AU (1) | AU3733300A (fr) |
CA (1) | CA2366723C (fr) |
CZ (1) | CZ20013123A3 (fr) |
HK (1) | HK1040486A1 (fr) |
RU (1) | RU2001127313A (fr) |
WO (1) | WO2000053231A2 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5994392A (en) * | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
US8552054B2 (en) * | 2001-03-23 | 2013-10-08 | Luitpold Pharmaceuticals, Inc. | Fatty amine drug conjugates |
JP4634694B2 (ja) * | 2001-03-23 | 2011-02-16 | ルイトポルド・ファーマシューティカルズ・インコーポレーテッド | 脂肪アルコール薬物複合体 |
US7169752B2 (en) | 2003-09-30 | 2007-01-30 | New River Pharmaceuticals Inc. | Compounds and compositions for prevention of overdose of oxycodone |
PT1509256E (pt) | 2002-05-24 | 2009-10-15 | Angiotech Int Ag | Composições e métodos de revestimento de implantes médicos |
CA2529125A1 (fr) | 2003-06-19 | 2004-12-23 | Yeda Research & Development Co. Ltd. | Lipopeptides antimicrobiens et anticancereux |
CA2544128A1 (fr) * | 2003-10-30 | 2005-05-12 | The Research Foundation Of State University Of New York | Conjugues taxoide/acide gras et preparations les contenant |
WO2006098241A1 (fr) * | 2005-03-14 | 2006-09-21 | Otsuka Pharmaceutical Factory, Inc. | Composition pharmaceutique contenant un médicament à peine soluble dans l'eau |
KR100753112B1 (ko) * | 2007-02-26 | 2007-08-29 | (주)고려다이나믹스 | 카드 발권 시스템 |
AU2013288738A1 (en) * | 2012-07-10 | 2015-01-29 | Baseclick Gmbh | Anandamide-modified nucleic acid molecules |
CN117088935A (zh) * | 2022-05-20 | 2023-11-21 | 上海维洱生物医药科技有限公司 | 一种雷公藤甲素木蜡酸酯及其脂质体与制备方法 |
KR20230174082A (ko) * | 2022-06-20 | 2023-12-27 | (주) 바이오인프라생명과학 | 약물을 전달하기 위한 초음파 감응형 약물전달체를 생성하는 방법 및 이를 이용한 초음파 감응형 약물전달체 |
WO2024110843A1 (fr) | 2022-11-21 | 2024-05-30 | Segena Corporation S.A. | Amélioration de l'activité immunomodulatrice d'oligonucléotides par modification de longue durée de dianophore : procédés et applications |
CN116676355B (zh) * | 2023-08-03 | 2023-10-24 | 成都第一制药有限公司 | 一种催化合成山莨菪碱的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5925327A (ja) * | 1982-07-31 | 1984-02-09 | Hidematsu Hirai | 抗腫瘍性複合体の製造方法 |
WO1993011668A1 (fr) * | 1991-12-10 | 1993-06-24 | Rush-Presbyterian-St. Luke's Medical Center | Procedes et compositions destines a reduire la multiresistance aux medicaments |
US5925669A (en) * | 1994-03-22 | 1999-07-20 | Molecular/Structural Bio Technologies, Inc. | Carrier compositions for anti-neoplastic drugs |
US5580899A (en) * | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
DK0914116T3 (da) * | 1996-05-22 | 2000-11-20 | Protarga Inc | Kompositstoffer omfattende konjugater af cis-docosahexaensyre og Taxotere |
US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
US6136988A (en) * | 1998-04-10 | 2000-10-24 | Hauser, Inc. | 7-hexanoyltaxol and methods for preparing the same |
-
2000
- 2000-03-09 CZ CZ20013123A patent/CZ20013123A3/cs unknown
- 2000-03-09 RU RU2001127313/14A patent/RU2001127313A/ru not_active Application Discontinuation
- 2000-03-09 KR KR1020017011387A patent/KR20020000147A/ko not_active Application Discontinuation
- 2000-03-09 EP EP00916188A patent/EP1163011A2/fr not_active Withdrawn
- 2000-03-09 JP JP2000603720A patent/JP2002538224A/ja active Pending
- 2000-03-09 CA CA2366723A patent/CA2366723C/fr not_active Expired - Fee Related
- 2000-03-09 AU AU37333/00A patent/AU3733300A/en not_active Abandoned
- 2000-03-09 CN CN00804762A patent/CN1377282A/zh active Pending
- 2000-03-09 WO PCT/US2000/006160 patent/WO2000053231A2/fr not_active Application Discontinuation
-
2002
- 2002-01-28 HK HK02100653.6A patent/HK1040486A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
KR20020000147A (ko) | 2002-01-04 |
EP1163011A2 (fr) | 2001-12-19 |
CN1377282A (zh) | 2002-10-30 |
WO2000053231A3 (fr) | 2001-10-04 |
CA2366723A1 (fr) | 2000-09-14 |
RU2001127313A (ru) | 2003-09-20 |
CZ20013123A3 (cs) | 2002-03-13 |
WO2000053231A2 (fr) | 2000-09-14 |
JP2002538224A (ja) | 2002-11-12 |
AU3733300A (en) | 2000-09-28 |
HK1040486A1 (zh) | 2002-06-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20170309 |