JP2002520000A - 免疫応答を刺激するための発現ベクターおよびそのベクターの使用方法 - Google Patents
免疫応答を刺激するための発現ベクターおよびそのベクターの使用方法Info
- Publication number
- JP2002520000A JP2002520000A JP2000548449A JP2000548449A JP2002520000A JP 2002520000 A JP2002520000 A JP 2002520000A JP 2000548449 A JP2000548449 A JP 2000548449A JP 2000548449 A JP2000548449 A JP 2000548449A JP 2002520000 A JP2002520000 A JP 2002520000A
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- Prior art keywords
- epitope
- peptide
- epitopes
- ctl
- htl
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
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| US7890498A | 1998-05-13 | 1998-05-13 | |
| US09/078,904 | 1998-05-13 | ||
| US8575198P | 1998-05-15 | 1998-05-15 | |
| US60/085,751 | 1998-05-15 | ||
| PCT/US1999/010646 WO1999058658A2 (en) | 1998-05-13 | 1999-05-13 | Expression vectors for stimulating an immune response and methods of using the same |
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| JP2002520000A true JP2002520000A (ja) | 2002-07-09 |
| JP2002520000A5 JP2002520000A5 (enExample) | 2005-04-21 |
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| JP2000548449A Pending JP2002520000A (ja) | 1998-05-13 | 1999-05-13 | 免疫応答を刺激するための発現ベクターおよびそのベクターの使用方法 |
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| US (4) | US6534482B1 (enExample) |
| EP (1) | EP1078092B1 (enExample) |
| JP (1) | JP2002520000A (enExample) |
| AT (1) | ATE518956T1 (enExample) |
| AU (1) | AU4078599A (enExample) |
| CA (2) | CA2685270C (enExample) |
| WO (1) | WO1999058658A2 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005028503A1 (ja) * | 2003-09-22 | 2005-03-31 | Green Peptide Co., Ltd. | Ｃ型肝炎ウイルス由来ペプチド |
| JP2007506443A (ja) * | 2003-06-09 | 2007-03-22 | コリクサ コーポレーション | Ｄｎａベクター |
| JP2016121149A (ja) * | 2009-08-26 | 2016-07-07 | セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． | Ｔ細胞ヘルプを誘発する組成物 |
Families Citing this family (141)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110097352A9 (en) * | 1992-01-29 | 2011-04-28 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions |
| US7611713B2 (en) | 1993-03-05 | 2009-11-03 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide compositions |
| US9340577B2 (en) | 1992-08-07 | 2016-05-17 | Epimmune Inc. | HLA binding motifs and peptides and their uses |
| DK0735893T3 (da) * | 1993-09-14 | 2009-03-09 | Pharmexa Inc | PAN DR-bindende peptider til styrkelse af immunsvaret |
| US20020182258A1 (en) * | 1997-01-22 | 2002-12-05 | Zycos Inc., A Delaware Corporation | Microparticles for delivery of nucleic acid |
| US6534482B1 (en) * | 1998-05-13 | 2003-03-18 | Epimmune, Inc. | Expression vectors for stimulating an immune response and methods of using the same |
| US6395714B1 (en) * | 1999-02-24 | 2002-05-28 | Aventis Pasteur Limited | Expressing gp140 fragment of primary HIV-1 isolate |
| EP1200109A4 (en) * | 1999-07-19 | 2005-06-15 | Epimmune Inc | USE OF PEPTIDE NUCLEIC ACID COMPOUNDS TO TRIGGER CELLULAR IMMUNE RESPONSES TO HEPATITIS C |
| US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
| US8128922B2 (en) | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| US7026443B1 (en) * | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
| US7462354B2 (en) * | 1999-12-28 | 2008-12-09 | Pharmexa Inc. | Method and system for optimizing minigenes and peptides encoded thereby |
| ATE366582T1 (de) * | 1999-12-28 | 2007-08-15 | Pharmexa Inc | Optimierte minigene und dadurch kodierte peptide |
| US20040248113A1 (en) * | 1999-12-28 | 2004-12-09 | Alessandro Sette | Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby |
| GB0009470D0 (en) * | 2000-04-17 | 2000-06-07 | Univ Southampton | Materials and methods relating to immune responses to fusion proteins |
| DK1363938T3 (en) | 2000-08-03 | 2014-03-24 | Univ Johns Hopkins | Molecular vaccine that connects an endoplasmic reticulum-chaperonepolypeptid with an antigen |
| JP2004522415A (ja) * | 2000-09-01 | 2004-07-29 | エピミューン インコーポレーティッド | Ｈｌａ結合ペプチドおよびその使用方法 |
| EP1313505A4 (en) * | 2000-09-01 | 2005-10-12 | Epimmune Inc | HLA BINDING PEPTIDES AND THEIR USES (18.03.02) |
| NO314588B1 (no) | 2000-09-04 | 2003-04-14 | Bionor Immuno As | HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV |
| CA2422506A1 (en) * | 2000-09-08 | 2002-03-14 | Epimmune Inc. | Inducing cellular immune responses to hepatitis b virus using peptide and nucleic acid compositions |
| EP1195381A1 (de) * | 2000-09-28 | 2002-04-10 | Immusystems GmbH | CD4+ T-Lymphozyten spezifische Hepatitis C Virus-Epitope |
| WO2003008537A2 (en) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
| US20060222656A1 (en) * | 2005-04-01 | 2006-10-05 | University Of Maryland, Baltimore | MAGE-A3/HPV 16 peptide vaccines for head and neck cancer |
| US7842480B2 (en) * | 2001-05-18 | 2010-11-30 | Mayo Foundation For Medical Education And Research | Chimeric antigen-specific t cell-activating polypeptides |
| WO2003015702A2 (en) * | 2001-08-16 | 2003-02-27 | The General Hospital Corporation | Epitopes of human immunodeficiency virus-1 |
| CA2357906A1 (en) | 2001-09-28 | 2003-03-28 | Institut Pasteur | Identification of new cd8 epitopes from hiv-1 proteins with therapeutical and vaccinal properties against hiv infections |
| FR2839722A1 (fr) * | 2002-05-17 | 2003-11-21 | Bio Merieux | Nouvelles compositions peptidiques et leur utilisation notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l'hepatite c |
| WO2004031210A2 (en) * | 2002-10-03 | 2004-04-15 | Epimmune Inc. | Optimized multi-epitope constructs and uses thereof |
| JP2006503914A (ja) * | 2002-10-21 | 2006-02-02 | エムジーアイ ファーマ バイオロジックス インコーポレイテッド | ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法 |
| EP1903056A3 (en) | 2002-12-10 | 2008-05-07 | Idm Pharma, Inc. | HLA-A1, -A2 -A3, -A24, -B7, and -B44 binding peptides comprising tumor associated antigen epitopes, and compositions thereof |
| EP1572740A2 (en) * | 2002-12-11 | 2005-09-14 | Pharmexa A/S | Targeting single epitopes |
| CA2519025A1 (en) * | 2003-03-28 | 2004-10-07 | The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services, Centers For Disea | Immunogenic hiv-1 multi-clade, multivalent constructs and methods of their use |
| CA2520768A1 (en) * | 2003-03-28 | 2005-02-10 | Idm Pharma, Inc. | Methods of identifying optimal variants of peptide epitopes |
| WO2005033265A2 (en) * | 2003-04-25 | 2005-04-14 | Epimmune Inc. | Optimized multi-epitope constructs and uses thereof |
| WO2004098526A2 (en) | 2003-05-05 | 2004-11-18 | Johns Hopkins University | Anti-cancer dna vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein |
| BR122018071808B8 (pt) | 2003-11-06 | 2020-06-30 | Seattle Genetics Inc | conjugado |
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| US20030216343A1 (en) | 2003-11-20 |
| WO1999058658A3 (en) | 2000-04-20 |
| US20030220285A1 (en) | 2003-11-27 |
| US6534482B1 (en) | 2003-03-18 |
| ATE518956T1 (de) | 2011-08-15 |
| CA2685270A1 (en) | 1999-11-18 |
| CA2331846A1 (en) | 1999-11-18 |
| AU4078599A (en) | 1999-11-29 |
| CA2685270C (en) | 2014-07-29 |
| EP1078092A2 (en) | 2001-02-28 |
| CA2331846C (en) | 2010-01-12 |
| WO1999058658A2 (en) | 1999-11-18 |
| US20030216342A1 (en) | 2003-11-20 |
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