JP2002519423A5 - - Google Patents
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- Publication number
- JP2002519423A5 JP2002519423A5 JP2000558098A JP2000558098A JP2002519423A5 JP 2002519423 A5 JP2002519423 A5 JP 2002519423A5 JP 2000558098 A JP2000558098 A JP 2000558098A JP 2000558098 A JP2000558098 A JP 2000558098A JP 2002519423 A5 JP2002519423 A5 JP 2002519423A5
- Authority
- JP
- Japan
- Prior art keywords
- alkoxy
- hydroxyl
- compound
- formula
- carboxyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 description 12
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 6
- 239000001301 oxygen Substances 0.000 description 6
- 229910052760 oxygen Inorganic materials 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 6
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 5
- -1 cyano, ethynyl Chemical group 0.000 description 5
- 125000004093 cyano group Chemical group *C#N 0.000 description 4
- 125000004453 alkoxycarbonyl group Chemical group 0.000 description 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 3
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 description 3
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 2
- 150000002431 hydrogen Chemical group 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 description 2
- 125000004694 alkoxyaminocarbonyl group Chemical group 0.000 description 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 125000003187 heptyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000001841 imino group Chemical group [H]N=* 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98112469.6 | 1998-07-06 | ||
| EP98112469 | 1998-07-06 | ||
| PCT/EP1999/004451 WO2000001695A1 (en) | 1998-07-06 | 1999-06-26 | New benzoxazoles with pde-inhibiting activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002519423A JP2002519423A (ja) | 2002-07-02 |
| JP2002519423A5 true JP2002519423A5 (enExample) | 2006-08-31 |
Family
ID=8232222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000558098A Withdrawn JP2002519423A (ja) | 1998-07-06 | 1999-06-26 | Ｐｅｄ阻害作用を有する新規ベンゾオキサゾール |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6376485B1 (enExample) |
| EP (1) | EP1095040B1 (enExample) |
| JP (1) | JP2002519423A (enExample) |
| AT (1) | ATE263166T1 (enExample) |
| AU (1) | AU761647B2 (enExample) |
| CA (1) | CA2336894A1 (enExample) |
| DE (1) | DE69916066T2 (enExample) |
| DK (1) | DK1095040T3 (enExample) |
| ES (1) | ES2219031T3 (enExample) |
| IL (1) | IL140468A0 (enExample) |
| PT (1) | PT1095040E (enExample) |
| SI (1) | SI1095040T1 (enExample) |
| WO (1) | WO2000001695A1 (enExample) |
| ZA (1) | ZA200100088B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA83620C2 (ru) | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| CA2625153A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
| JP2010502722A (ja) | 2006-09-08 | 2010-01-28 | ブレインセルス，インコーポレイティド | ４−アシルアミノピリジン誘導体を含む組み合わせ |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| EP2225215A1 (en) * | 2007-11-21 | 2010-09-08 | Decode Genetics EHF | Substituted benzoazole pde4 inhibitors for treating inflammatory, cardiovascular and cns disorders |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405633A (en) * | 1982-03-01 | 1983-09-20 | Usv Pharmaceutical Corporation | Method of treatment of asthma |
| US4490373A (en) * | 1983-05-20 | 1984-12-25 | Usv Pharmaceutical Corporation | Method of treating asthma |
| KR100237962B1 (ko) * | 1994-10-12 | 2000-02-01 | 그린 마틴 | 신규한 벤즈옥사졸 |
| DE59610031D1 (de) * | 1995-05-18 | 2003-02-06 | Altana Pharma Ag | Cyclohexyldihydrobenzofurane |
| WO1996036624A1 (en) * | 1995-05-19 | 1996-11-21 | Kyowa Hakko Kogyo Co., Ltd. | Oxygen-containing heterocyclic compounds |
-
1999
- 1999-06-26 WO PCT/EP1999/004451 patent/WO2000001695A1/en not_active Ceased
- 1999-06-26 SI SI9930588T patent/SI1095040T1/xx unknown
- 1999-06-26 DK DK99931198T patent/DK1095040T3/da active
- 1999-06-26 PT PT99931198T patent/PT1095040E/pt unknown
- 1999-06-26 ES ES99931198T patent/ES2219031T3/es not_active Expired - Lifetime
- 1999-06-26 ZA ZA200100088A patent/ZA200100088B/en unknown
- 1999-06-26 DE DE69916066T patent/DE69916066T2/de not_active Expired - Fee Related
- 1999-06-26 IL IL14046899A patent/IL140468A0/xx not_active IP Right Cessation
- 1999-06-26 AT AT99931198T patent/ATE263166T1/de not_active IP Right Cessation
- 1999-06-26 CA CA002336894A patent/CA2336894A1/en not_active Abandoned
- 1999-06-26 US US09/720,812 patent/US6376485B1/en not_active Expired - Fee Related
- 1999-06-26 JP JP2000558098A patent/JP2002519423A/ja not_active Withdrawn
- 1999-06-26 EP EP99931198A patent/EP1095040B1/en not_active Expired - Lifetime
- 1999-06-26 AU AU47786/99A patent/AU761647B2/en not_active Ceased
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