JP2002513750A - 溶媒/助溶剤を含まないマイクロエマルジョン及びエマルジョンプレ濃縮物のドラッグデリバリーシステム - Google Patents
溶媒/助溶剤を含まないマイクロエマルジョン及びエマルジョンプレ濃縮物のドラッグデリバリーシステムInfo
- Publication number
- JP2002513750A JP2002513750A JP2000546754A JP2000546754A JP2002513750A JP 2002513750 A JP2002513750 A JP 2002513750A JP 2000546754 A JP2000546754 A JP 2000546754A JP 2000546754 A JP2000546754 A JP 2000546754A JP 2002513750 A JP2002513750 A JP 2002513750A
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- composition
- microemulsion
- drugs
- concentrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8451898P | 1998-05-07 | 1998-05-07 | |
US60/084,518 | 1998-05-07 | ||
PCT/IE1999/000031 WO1999056727A2 (en) | 1998-05-07 | 1999-05-07 | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2002513750A true JP2002513750A (ja) | 2002-05-14 |
Family
ID=22185451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000546754A Pending JP2002513750A (ja) | 1998-05-07 | 1999-05-07 | 溶媒/助溶剤を含まないマイクロエマルジョン及びエマルジョンプレ濃縮物のドラッグデリバリーシステム |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1075252A2 (de) |
JP (1) | JP2002513750A (de) |
AU (1) | AU3843999A (de) |
CA (1) | CA2331640A1 (de) |
WO (1) | WO1999056727A2 (de) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006514103A (ja) * | 2002-11-01 | 2006-04-27 | バイオデリバリー サイエンシーズ インターナショナル インコーポレイティッド | ジオデート送達媒体 |
JP2006526579A (ja) * | 2003-03-18 | 2006-11-24 | アドバンスト メディカル オプティクス, インコーポレーテッド | 自己乳化組成物、その使用および製造方法 |
JPWO2005089714A1 (ja) * | 2004-03-24 | 2008-01-31 | 武田薬品工業株式会社 | エマルション安定化製剤 |
JP2008516890A (ja) * | 2004-08-06 | 2008-05-22 | トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド | 新規なフェノフィブラート製剤および関連治療方法 |
JP2009504805A (ja) * | 2005-08-09 | 2009-02-05 | ナノバイオ コーポレーション | 抗炎症活性を有するナノエマルジョン組成物 |
JP2009515990A (ja) * | 2005-11-17 | 2009-04-16 | バイオアバイラビリティ,インク. | 生体適合性潜在的乳化剤 |
JP2010150289A (ja) * | 2004-03-10 | 2010-07-08 | Bayer Schering Pharma Ag | 分子分散されたドロスピレノンを含む組成物 |
WO2010134614A1 (ja) * | 2009-05-22 | 2010-11-25 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
JP2010536826A (ja) * | 2007-08-21 | 2010-12-02 | バジリア ファルマスーチカ アーゲー | 抗真菌組成物 |
JP2011006380A (ja) * | 2009-05-22 | 2011-01-13 | Mochida Pharmaceut Co Ltd | ω3脂肪酸の乳化組成物 |
JP2012519728A (ja) * | 2009-03-09 | 2012-08-30 | プロノヴァ・バイオファーマ・ノルゲ・アーエス | 脂肪酸油混合物及び界面活性剤を含む組成物、並びにその方法及び使用 |
JP2014098039A (ja) * | 2007-11-21 | 2014-05-29 | Innopharmax Inc | 生物学的利用能を向上した医薬組成物 |
JP2017523142A (ja) * | 2014-06-25 | 2017-08-17 | シネルジア・バイオ・サイエンシーズ・プライベイト・リミテッドSynergia Bio Sciences Private Limited | 医薬水中油型ナノエマルジョン |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
AU7638200A (en) * | 1999-10-20 | 2001-04-30 | Vesifact Ag | Microemulsion preconcentrates which contain cyclosporines and corresponding microemulsions |
EP1296923B3 (de) | 2000-02-16 | 2012-04-11 | The Brigham And Women's Hospital, Inc. | Aspirin-ausgelöste lipidmediatoren |
SE0000774D0 (sv) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
SE0000773D0 (sv) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
US6596306B1 (en) * | 2000-07-07 | 2003-07-22 | David Ho Sue San Ho | Drug delivery system:formulation for fat-soluble drugs |
MY120392A (en) * | 2000-06-08 | 2005-10-31 | Hovid Berhad | A novel drug delivery system : formulation for fat-soluble drugs |
JP4593074B2 (ja) * | 2000-10-11 | 2010-12-08 | セフアロン・インコーポレーテツド | モダフィニル化合物含有組成物 |
FR2818905A1 (fr) * | 2000-12-28 | 2002-07-05 | Cll Pharma | Compositions pharmaceutiques colloidales micellaires renfermant un principe actif lipophile |
EP1377273B1 (de) * | 2001-02-11 | 2009-03-18 | Aquanova Ag | Verfahren zur herstellung eines isoflavon-konzentrats |
IL157130A0 (en) * | 2001-02-14 | 2004-02-08 | Gw Pharma Ltd | A cannabis based pharmaceutical formulation |
DE50101395D1 (de) * | 2001-04-12 | 2004-03-04 | Vesifact Ag Baar | Pharmazeutische Formulierungen enthaltend entzündungshemmende Wirkstoffe und deren Verwendung |
SE0102993D0 (sv) | 2001-09-07 | 2001-09-07 | Astrazeneca Ab | New self emulsifying drug delivery system |
US7030159B2 (en) | 2001-12-18 | 2006-04-18 | The Brigham And Women's Hospital, Inc. | Approach to anti-microbial host defense with molecular shields with EPA and DHA analogs |
KR100441167B1 (ko) * | 2001-12-27 | 2004-07-21 | 씨제이 주식회사 | 마이크로에멀젼 예비 농축액 조성물 |
US7582785B2 (en) | 2002-04-01 | 2009-09-01 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
CA2493878C (en) | 2002-07-30 | 2013-07-23 | Wyeth | Parenteral formulations containing a rapamycin hydroxyester |
US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
EP1537067B1 (de) | 2002-08-12 | 2009-11-18 | Brigham And Women's Hospital | Resolvine: biotemplate zur durchführung therapeutischer anwendungen |
US7842791B2 (en) | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
FR2853527B1 (fr) * | 2003-04-11 | 2006-06-23 | Oreal | Composition sous forme d'une emulsion huile-dans-eau contenant un polymere amphiphile, et ses utilisations notamment cosmetiques |
US7879345B2 (en) | 2003-04-11 | 2011-02-01 | L'oreal | Composition containing an amphiphilic polymer, uses thereof |
US20050232974A1 (en) * | 2004-04-19 | 2005-10-20 | Gore Makarand P | System and a method for pharmaceutical dosage preparation using jettable microemulsions |
CN100361656C (zh) | 2004-08-27 | 2008-01-16 | 石药集团中奇制药技术(石家庄)有限公司 | 丁苯酞自乳化释药体系及其制备方法和应用 |
GT200500310A (es) | 2004-11-19 | 2006-06-19 | Compuestos organicos | |
US8273792B2 (en) | 2005-10-03 | 2012-09-25 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin D1/protectin D1 and it's natural stereoisomers |
US20140287004A1 (en) * | 2005-11-14 | 2014-09-25 | The Trustees Of Columbia University In The City Of New York | Use of an Omega-3 Lipid-Based Emulsion Following Ischemic Injury to Provide Protection and Recovery in Human Organs |
WO2014160989A2 (en) | 2013-03-28 | 2014-10-02 | The Trustees Of Columbia University In The City Of New York | Reperfusion with omega-3 glycerides promotes donor organ protection for transplantation |
WO2007059431A1 (en) * | 2005-11-14 | 2007-05-24 | The Trustees Of Columbia University In The City Of New York | Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs |
MY153288A (en) * | 2006-06-28 | 2015-01-29 | Hovid Berhad | An effective pharmaceutical carrier for poorly bioavailable drugs |
PT2068825E (pt) * | 2006-10-04 | 2011-02-11 | M & P Patent Ag | Sistema de administração de libertação controlada para aplicação nasal de neurotransmissores |
FR2925855B1 (fr) | 2007-12-26 | 2010-11-05 | Virbac Sa | Composition liquide autoemulsionnable de florfenicol destinee a etre incorporee a l'eau de boisson des animaux d'elevage. |
US9717703B2 (en) | 2009-10-16 | 2017-08-01 | Glaxosmithkline Llc | Emulsion and emulsion preconcentrate compositions comprising omega-3 fatty acids and uses thereof are disclosed |
KR20200013123A (ko) * | 2009-10-23 | 2020-02-05 | 바스프 에이에스 | 지방산 오일 혼합물의 코팅된 캡슐 및 정제 |
EP2366408B1 (de) | 2010-03-01 | 2012-07-18 | Laboratorios SALVAT, S.A. | Wässrige klare Lösungen aus Fluocinolon-Acetonid zur Behandlung von Ohrentzündungen |
KR101752944B1 (ko) | 2010-05-03 | 2017-07-03 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법 |
AR082930A1 (es) * | 2010-09-08 | 2013-01-16 | Pronova Biopharma Norge As | Composiciones que comprenden una mezcla oleosa de acidos grasos, un tensioactivo y una estatina |
EP2613767A4 (de) * | 2010-09-08 | 2014-03-19 | Pronova Biopharma Norge As | Zusammensetzungen mit einer fettsäure-öl-mischung, einer freien fettsäure, einem tensid und einem statin |
EP2613766A4 (de) * | 2010-09-08 | 2014-04-09 | Pronova Biopharma Norge As | Zusammensetzungen mit einer fettsäure-öl-mischung mit epa und dha in freier säureform, einem tensid und einem statin |
JO3337B1 (ar) * | 2010-12-13 | 2019-03-13 | Debiopharm Sa | تركيبات صيدلية تشمل أليسبوريفير |
JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
US11400048B2 (en) | 2014-06-25 | 2022-08-02 | Synergia Bio Sciences Private Limited | Pharmaceutical oil-in-water nano-emulsion |
US11260018B2 (en) | 2015-09-17 | 2022-03-01 | Jrx Biotechnology, Inc. | Approaches for improving skin hydration and moisturization |
US20230158018A1 (en) * | 2018-09-13 | 2023-05-25 | Ftf Pharma Private Limited | Non-aqueous chemotherapeutic suspensions for oral dosage |
US20200215027A1 (en) * | 2018-12-28 | 2020-07-09 | Robert K. Prud'homme | Dihydromyricetin nanoemulsion formulations and methods for forming them |
US11465107B2 (en) * | 2019-01-31 | 2022-10-11 | Hong Ngoc Thi Dang | Process for producing a nano omega-3 microemulsion system |
CZ309587B6 (cs) * | 2021-01-22 | 2023-05-03 | Oncora S.R.O. | Mikroemulzní prekoncentrát s obsahem kladribinu a způsob jeho přípravy |
Family Cites Families (13)
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IT1090703B (it) * | 1976-12-03 | 1985-06-26 | Scherer Ltd R P | Perfezionamento nelle composizioni utili quali veicolo per farmaci |
US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
SG49746A1 (en) * | 1992-08-28 | 1998-06-15 | Pharmos Corp | Submicron emulsions as ocular drug delivery vehicles |
CN1077800C (zh) * | 1993-07-01 | 2002-01-16 | 韩美药品工业株式会社 | 环孢菌素软胶囊组合物 |
FR2710535B1 (fr) * | 1993-09-30 | 1995-11-24 | Gattefosse Ets Sa | Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion. |
IL107471A (en) * | 1993-11-02 | 1997-09-30 | Yissum Res Dev Co | Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production |
ES2270426T3 (es) * | 1994-03-18 | 2007-04-01 | Supernus Pharmaceuticals, Inc. | Sistema de suministros de farmacos emulsionados. |
IL115742A (en) * | 1994-10-26 | 2000-06-01 | Novartis Ag | Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant |
EP0760237A1 (de) * | 1995-08-30 | 1997-03-05 | Cipla Limited | Öl-in-Wasser-Mikroemulsionen |
KR980008239A (ko) * | 1996-07-26 | 1998-04-30 | 김충환 | 사이클로스포린-함유 약학적 조성물 |
FR2753376B1 (fr) * | 1996-09-18 | 1998-10-16 | Synthelabo | Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques |
EP1039893B1 (de) * | 1997-12-10 | 2011-02-02 | Cyclosporine Therapeutics Limited | Omega-3 fettsäure enthaltende pharmazeutische zusammensetzungen |
WO1999029300A1 (en) * | 1997-12-10 | 1999-06-17 | Rtp Pharma Inc. | Self-emulsifying fenofibrate formulations |
-
1999
- 1999-05-07 JP JP2000546754A patent/JP2002513750A/ja active Pending
- 1999-05-07 WO PCT/IE1999/000031 patent/WO1999056727A2/en not_active Application Discontinuation
- 1999-05-07 AU AU38439/99A patent/AU3843999A/en not_active Abandoned
- 1999-05-07 CA CA002331640A patent/CA2331640A1/en not_active Abandoned
- 1999-05-07 EP EP99921098A patent/EP1075252A2/de not_active Withdrawn
Cited By (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006514103A (ja) * | 2002-11-01 | 2006-04-27 | バイオデリバリー サイエンシーズ インターナショナル インコーポレイティッド | ジオデート送達媒体 |
JP2006526579A (ja) * | 2003-03-18 | 2006-11-24 | アドバンスト メディカル オプティクス, インコーポレーテッド | 自己乳化組成物、その使用および製造方法 |
JP2010150289A (ja) * | 2004-03-10 | 2010-07-08 | Bayer Schering Pharma Ag | 分子分散されたドロスピレノンを含む組成物 |
JPWO2005089714A1 (ja) * | 2004-03-24 | 2008-01-31 | 武田薬品工業株式会社 | エマルション安定化製剤 |
JP2008516890A (ja) * | 2004-08-06 | 2008-05-22 | トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド | 新規なフェノフィブラート製剤および関連治療方法 |
JP2009504805A (ja) * | 2005-08-09 | 2009-02-05 | ナノバイオ コーポレーション | 抗炎症活性を有するナノエマルジョン組成物 |
JP2009515990A (ja) * | 2005-11-17 | 2009-04-16 | バイオアバイラビリティ,インク. | 生体適合性潜在的乳化剤 |
JP2010536826A (ja) * | 2007-08-21 | 2010-12-02 | バジリア ファルマスーチカ アーゲー | 抗真菌組成物 |
JP2014098039A (ja) * | 2007-11-21 | 2014-05-29 | Innopharmax Inc | 生物学的利用能を向上した医薬組成物 |
JP2016106152A (ja) * | 2007-11-21 | 2016-06-16 | イノファーマックス インコーポレイテッド | 生物学的利用能を向上した医薬組成物 |
JP2018090600A (ja) * | 2009-03-09 | 2018-06-14 | プロノヴァ・バイオファーマ・ノルゲ・アーエス | 脂肪酸油混合物及び界面活性剤を含む組成物、並びにその方法及び使用 |
JP2012519728A (ja) * | 2009-03-09 | 2012-08-30 | プロノヴァ・バイオファーマ・ノルゲ・アーエス | 脂肪酸油混合物及び界面活性剤を含む組成物、並びにその方法及び使用 |
JP2016128425A (ja) * | 2009-03-09 | 2016-07-14 | プロノヴァ・バイオファーマ・ノルゲ・アーエス | 脂肪酸油混合物及び界面活性剤を含む組成物、並びにその方法及び使用 |
WO2010134614A1 (ja) * | 2009-05-22 | 2010-11-25 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
US9579281B2 (en) | 2009-05-22 | 2017-02-28 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of ω3 fatty acid |
US9089483B2 (en) | 2009-05-22 | 2015-07-28 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of OMEGA3 fatty acid |
JP2015187177A (ja) * | 2009-05-22 | 2015-10-29 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
JP5313343B2 (ja) * | 2009-05-22 | 2013-10-09 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
JP2016128508A (ja) * | 2009-05-22 | 2016-07-14 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
JP2013177472A (ja) * | 2009-05-22 | 2013-09-09 | Mochida Pharmaceut Co Ltd | ω3脂肪酸の自己乳化組成物 |
US8618168B2 (en) | 2009-05-22 | 2013-12-31 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of OMEGA3 fatty acid |
JP2017137361A (ja) * | 2009-05-22 | 2017-08-10 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
US11207286B2 (en) | 2009-05-22 | 2021-12-28 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of w3 fatty acid |
JP2011006380A (ja) * | 2009-05-22 | 2011-01-13 | Mochida Pharmaceut Co Ltd | ω3脂肪酸の乳化組成物 |
US10092536B2 (en) | 2009-05-22 | 2018-10-09 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of ω3 fatty acid |
JP2019001823A (ja) * | 2009-05-22 | 2019-01-10 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
US10493052B2 (en) | 2009-05-22 | 2019-12-03 | Mochida Pharmaceutical Co., Ltd. | Self-emulsifying composition of ω3 fatty acid |
JP2020094072A (ja) * | 2009-05-22 | 2020-06-18 | 持田製薬株式会社 | ω3脂肪酸の自己乳化組成物 |
JP2017523142A (ja) * | 2014-06-25 | 2017-08-17 | シネルジア・バイオ・サイエンシーズ・プライベイト・リミテッドSynergia Bio Sciences Private Limited | 医薬水中油型ナノエマルジョン |
Also Published As
Publication number | Publication date |
---|---|
WO1999056727A2 (en) | 1999-11-11 |
CA2331640A1 (en) | 1999-11-11 |
AU3843999A (en) | 1999-11-23 |
WO1999056727A3 (en) | 2000-03-02 |
EP1075252A2 (de) | 2001-02-14 |
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