JP2002507391A - 繊維ノブのｈｉループに異種ペプチドエピトープを含有するアデノウイルスベクター - Google Patents
繊維ノブのｈｉループに異種ペプチドエピトープを含有するアデノウイルスベクターInfo
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- JP2002507391A JP2002507391A JP2000530231A JP2000530231A JP2002507391A JP 2002507391 A JP2002507391 A JP 2002507391A JP 2000530231 A JP2000530231 A JP 2000530231A JP 2000530231 A JP2000530231 A JP 2000530231A JP 2002507391 A JP2002507391 A JP 2002507391A
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- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 description 1
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- 210000002325 somatostatin-secreting cell Anatomy 0.000 description 1
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- MPLHNVLQVRSVEE-UHFFFAOYSA-N texas red Chemical compound [O-]S(=O)(=O)C1=CC(S(Cl)(=O)=O)=CC=C1C(C1=CC=2CCCN3CCCC(C=23)=C1O1)=C2C1=C(CCC1)C3=[N+]1CCCC3=C2 MPLHNVLQVRSVEE-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7394798P | 1998-02-06 | 1998-02-06 | |
| US60/073,947 | 1998-02-06 | ||
| US9980198P | 1998-09-10 | 1998-09-10 | |
| US60/099,801 | 1998-09-10 | ||
| PCT/US1999/002549 WO1999039734A1 (en) | 1998-02-06 | 1999-02-05 | Adenovirus vector containing a heterologous peptide epitope in the hi loop of the fiber knob |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002507391A true JP2002507391A (ja) | 2002-03-12 |
| JP2002507391A5 JP2002507391A5 (https=) | 2006-03-30 |
Family
ID=26755086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000530231A Pending JP2002507391A (ja) | 1998-02-06 | 1999-02-05 | 繊維ノブのｈｉループに異種ペプチドエピトープを含有するアデノウイルスベクター |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7297542B2 (https=) |
| EP (1) | EP1053013A4 (https=) |
| JP (1) | JP2002507391A (https=) |
| KR (1) | KR20010034487A (https=) |
| CN (1) | CN1304316A (https=) |
| AU (1) | AU744252B2 (https=) |
| BR (1) | BR9908613A (https=) |
| CA (1) | CA2327545A1 (https=) |
| IL (1) | IL137681A0 (https=) |
| NO (1) | NO20003956L (https=) |
| WO (1) | WO1999039734A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006514538A (ja) * | 2002-07-10 | 2006-05-11 | トランスジーン ソシエテ アノニム | 細胞受容体への結合が除去された改変アデノウイルス繊維 |
| JP2015511822A (ja) * | 2012-03-13 | 2015-04-23 | ソーク インスティテュート フォー バイオロジカル スタディーズ | アデノウイルスおよび化学二量体を用いる選択細胞の標的化 |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7157266B2 (en) * | 1999-01-25 | 2007-01-02 | Brookhaven Science Associates Llc | Structure of adenovirus bound to cellular receptor car |
| US6395875B1 (en) * | 1999-01-25 | 2002-05-28 | Brookhaven Science Associates Llc | Recombinant soluble adenovirus receptor |
| AU783879B2 (en) | 1999-11-25 | 2005-12-15 | Transgene S.A. | Modified adenovirus fibre and uses |
| CA2405469C (en) | 2000-04-12 | 2012-03-20 | Amersham Health As | Integrin binding peptide derivatives |
| AU6368901A (en) | 2000-05-31 | 2001-12-11 | Univ Saskatchewan | Modified bovine adenovirus having altered tropism |
| JP3635462B2 (ja) | 2000-05-31 | 2005-04-06 | 国立医薬品食品衛生研究所長 | アデノウイルスベクター |
| NO20004795D0 (no) | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
| BRPI0210886B8 (pt) | 2001-07-10 | 2021-05-25 | Amersham Health As | composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal |
| WO2003029448A1 (en) | 2001-09-29 | 2003-04-10 | Yun, Chae-Ok | Recombinant adenovirus with enhanced therapeutic effect and pharmaceutical composition comprising said recombinant adenovirus |
| US20060281090A1 (en) * | 2003-05-01 | 2006-12-14 | University Of Washington Uw Tech Transfer- Invention Licensing | Capsid-modified adenovirus vectors and methods of using the same |
| JP2007503843A (ja) * | 2003-05-14 | 2007-03-01 | イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー | アデノウイルス親和性の拡大 |
| CA2543200A1 (en) * | 2003-10-24 | 2005-05-06 | National Research Council Of Canada | Ligand-pseudoreceptor system for generation of adenoviral vectors with altered tropism |
| US10337054B2 (en) | 2004-02-02 | 2019-07-02 | Quantum-Si Incorporated | Enrichment of nucleic acid targets |
| EP1720636A4 (en) | 2004-02-02 | 2012-06-20 | Univ British Columbia | SCODAPHORESIS AND METHOD AND DEVICES FOR MOVING AND CONCENTRATING PARTICLES |
| US9186685B2 (en) | 2012-01-13 | 2015-11-17 | The University Of British Columbia | Multiple arm apparatus and methods for separation of particles |
| US8529744B2 (en) | 2004-02-02 | 2013-09-10 | Boreal Genomics Corp. | Enrichment of nucleic acid targets |
| US7473418B2 (en) | 2004-03-25 | 2009-01-06 | Cell Genesys, Inc. | Pan cancer oncolytic vectors and methods of use thereof |
| DE102004021584A1 (de) * | 2004-05-03 | 2005-12-01 | Stefan Kochanek | Modifizierte virale Vektorpartikel |
| US7776322B2 (en) | 2004-08-16 | 2010-08-17 | Stefan Kochanek | Modified viral vector particles |
| CA2496294A1 (en) * | 2005-02-07 | 2006-08-07 | The University Of British Columbia | Apparatus and methods for concentrating and separating particles such as molecules |
| WO2007123737A2 (en) | 2006-03-30 | 2007-11-01 | University Of California | Methods and compositions for localized secretion of anti-ctla-4 antibodies |
| US7919079B2 (en) | 2006-03-31 | 2011-04-05 | Biosante Pharmaceuticals, Inc. | Cancer immunotherapy compositions and methods of use |
| US20100272753A1 (en) * | 2006-10-26 | 2010-10-28 | The Johns Hopkins University | Recombinant Adenovirus Vaccines |
| US8475641B2 (en) * | 2008-02-01 | 2013-07-02 | The University Of British Columbia | Methods and apparatus for particle introduction and recovery |
| WO2009137211A2 (en) * | 2008-05-04 | 2009-11-12 | University Of Maryland Biotechnology Institute Off. Of Research Admin./ Tech. Dev. | Fibrous assemblies for antibody presentation, and multiplexed antigenic analysis using same |
| US20110256055A1 (en) | 2008-12-23 | 2011-10-20 | Ge Healthcare Limited | Application of 99mtc peptide-based compound as a bone marrow imaging agent |
| US8877028B2 (en) | 2009-04-21 | 2014-11-04 | The University Of British Columbia | System and methods for detection of particles |
| ES2385251B1 (es) | 2009-05-06 | 2013-05-06 | Fundació Privada Institut D'investigació Biomèdica De Bellvitge | Adenovirus oncolíticos para el tratamiento del cáncer. |
| WO2012006145A2 (en) * | 2010-06-29 | 2012-01-12 | The Johns Hopkins University | Com positions and methods for retargeting virus constructs |
| CA2742327A1 (en) | 2011-05-20 | 2012-11-20 | The University Of British Columiba | Systems and methods for enhanced scoda |
| EP2798069B1 (en) * | 2011-12-15 | 2017-03-29 | Washington University | Porcine knob xenotype chimeric adenoviral vector for dendritic cell infection |
| WO2013166444A2 (en) | 2012-05-04 | 2013-11-07 | Boreal Genomics Corp. | Biomarker analysis using scodaphoresis |
| SG11201507393TA (en) | 2013-03-14 | 2015-10-29 | Salk Inst For Biological Studi | Oncolytic adenovirus compositions |
| US9340835B2 (en) | 2013-03-15 | 2016-05-17 | Boreal Genomics Corp. | Method for separating homoduplexed and heteroduplexed nucleic acids |
| CN104634978A (zh) * | 2013-11-13 | 2015-05-20 | 长春百克生物科技股份公司 | 一种分型检测腺病毒中和抗体的方法以及用于分型检测腺病毒中和抗体的试剂盒 |
| CN106714845A (zh) * | 2014-08-11 | 2017-05-24 | 得克萨斯州大学系统董事会 | 通过crispr/cas9介导的基因编辑预防肌营养不良 |
| KR102608590B1 (ko) | 2014-09-24 | 2023-12-01 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| WO2016185284A1 (en) | 2015-05-20 | 2016-11-24 | Boreal Genomics, Inc. | Method for isolating target nucleic acid using heteroduplex binding proteins |
| WO2017147269A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| EP3532082A4 (en) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES |
| KR20190098215A (ko) | 2016-12-21 | 2019-08-21 | 멤젠 엘엘씨 | 무장된 복제-가능 종양 분해 아데노바이러스 |
| PE20200488A1 (es) | 2017-06-27 | 2020-03-03 | Regeneron Pharma | Vectores virales recombinantes con tropismo modificado y usos de estos para la introduccion dirigida de material genetico a celulas humanas |
| CN112292449A (zh) | 2018-04-09 | 2021-01-29 | 萨克生物研究学院 | 具有增强的复制特性的溶瘤腺病毒组合物 |
| EP3927833A4 (en) | 2019-02-21 | 2022-11-30 | Unleash Immuno Oncolytics, Inc. | ONCOLYTIC ADENOVIRAL VECTOR AND METHODS OF USE |
| US12011716B2 (en) | 2019-10-29 | 2024-06-18 | Quantum-Si Incorporated | Peristaltic pumping of fluids and associated methods, systems, and devices |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9223084D0 (en) | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
| US5846782A (en) * | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| JP2001520511A (ja) * | 1995-12-08 | 2001-10-30 | ザ ユーナヴァーサティ オブ アラバマ アト バーミングハム リサーチ ファンデーション | 向標的性アデノウイルス・ベクター |
| ATE540686T1 (de) * | 1999-05-12 | 2012-01-15 | Uab Research Foundation | Adenovirus mit erhöhter infektiosität und konditionaler replikationsfähigkeit und deren verwendungen |
-
1999
- 1999-02-05 IL IL13768199A patent/IL137681A0/xx unknown
- 1999-02-05 EP EP99906761A patent/EP1053013A4/en not_active Withdrawn
- 1999-02-05 CA CA002327545A patent/CA2327545A1/en not_active Abandoned
- 1999-02-05 KR KR1020007008593A patent/KR20010034487A/ko not_active Withdrawn
- 1999-02-05 JP JP2000530231A patent/JP2002507391A/ja active Pending
- 1999-02-05 CN CN99804659A patent/CN1304316A/zh active Pending
- 1999-02-05 AU AU26595/99A patent/AU744252B2/en not_active Ceased
- 1999-02-05 US US09/245,603 patent/US7297542B2/en not_active Expired - Fee Related
- 1999-02-05 BR BR9908613-1A patent/BR9908613A/pt not_active IP Right Cessation
- 1999-02-05 WO PCT/US1999/002549 patent/WO1999039734A1/en not_active Ceased
-
2000
- 2000-08-04 NO NO20003956A patent/NO20003956L/no not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006514538A (ja) * | 2002-07-10 | 2006-05-11 | トランスジーン ソシエテ アノニム | 細胞受容体への結合が除去された改変アデノウイルス繊維 |
| JP2015511822A (ja) * | 2012-03-13 | 2015-04-23 | ソーク インスティテュート フォー バイオロジカル スタディーズ | アデノウイルスおよび化学二量体を用いる選択細胞の標的化 |
Also Published As
| Publication number | Publication date |
|---|---|
| NO20003956L (no) | 2000-10-05 |
| US20020081280A1 (en) | 2002-06-27 |
| AU744252B2 (en) | 2002-02-21 |
| IL137681A0 (en) | 2001-10-31 |
| EP1053013A4 (en) | 2004-12-22 |
| WO1999039734A1 (en) | 1999-08-12 |
| AU2659599A (en) | 1999-08-23 |
| KR20010034487A (ko) | 2001-04-25 |
| EP1053013A1 (en) | 2000-11-22 |
| US7297542B2 (en) | 2007-11-20 |
| BR9908613A (pt) | 2000-10-31 |
| CN1304316A (zh) | 2001-07-18 |
| NO20003956D0 (no) | 2000-08-04 |
| CA2327545A1 (en) | 1999-08-12 |
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