JP2002029986A - 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 - Google Patents
真皮コラーゲン線維束再構築剤及びそれを含有する組成物Info
- Publication number
- JP2002029986A JP2002029986A JP2000218617A JP2000218617A JP2002029986A JP 2002029986 A JP2002029986 A JP 2002029986A JP 2000218617 A JP2000218617 A JP 2000218617A JP 2000218617 A JP2000218617 A JP 2000218617A JP 2002029986 A JP2002029986 A JP 2002029986A
- Authority
- JP
- Japan
- Prior art keywords
- collagen fiber
- fiber bundle
- hypericum
- hypericaceae
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000008186 Collagen Human genes 0.000 title claims abstract description 72
- 108010035532 Collagen Proteins 0.000 title claims abstract description 72
- 229920001436 collagen Polymers 0.000 title claims abstract description 72
- 239000000835 fiber Substances 0.000 title claims abstract description 70
- 239000003795 chemical substances by application Substances 0.000 title claims abstract description 43
- 239000000203 mixture Substances 0.000 title description 5
- 241000196324 Embryophyta Species 0.000 claims abstract description 34
- 230000037303 wrinkles Effects 0.000 claims abstract description 24
- 241000782597 Hypericum erectum Species 0.000 claims abstract description 7
- 239000002798 polar solvent Substances 0.000 claims abstract description 7
- 230000002500 effect on skin Effects 0.000 claims description 32
- 210000003491 skin Anatomy 0.000 claims description 32
- 210000004207 dermis Anatomy 0.000 claims description 31
- 238000002360 preparation method Methods 0.000 claims description 26
- 235000017309 Hypericum perforatum Nutrition 0.000 claims description 23
- 238000007634 remodeling Methods 0.000 claims description 23
- 241000832224 Hypericaceae Species 0.000 claims description 21
- 241000546188 Hypericum Species 0.000 claims description 18
- 244000141009 Hypericum perforatum Species 0.000 claims description 5
- 241001533088 Hypericum ascyron Species 0.000 claims description 3
- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 244000219416 Hypericum japonicum Species 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000006872 improvement Effects 0.000 abstract description 5
- 230000002265 prevention Effects 0.000 abstract description 3
- 206010040954 Skin wrinkling Diseases 0.000 description 20
- 230000000694 effects Effects 0.000 description 19
- 239000000686 essence Substances 0.000 description 14
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 208000035475 disorder Diseases 0.000 description 8
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- 239000004006 olive oil Substances 0.000 description 2
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- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
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- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
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- WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 description 1
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 description 1
- GECRRQVLQHRVNH-MRCUWXFGSA-N 2-octyldodecyl (z)-octadec-9-enoate Chemical compound CCCCCCCCCCC(CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC GECRRQVLQHRVNH-MRCUWXFGSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- XPFCZYUVICHKDS-UHFFFAOYSA-N 3-methylbutane-1,3-diol Chemical compound CC(C)(O)CCO XPFCZYUVICHKDS-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- 101000783705 Myxoma virus (strain Uriarra) Envelope protein A28 homolog Proteins 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
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- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
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- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 description 1
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Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000218617A JP2002029986A (ja) | 2000-07-19 | 2000-07-19 | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000218617A JP2002029986A (ja) | 2000-07-19 | 2000-07-19 | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002029986A true JP2002029986A (ja) | 2002-01-29 |
| JP2002029986A5 JP2002029986A5 (enExample) | 2007-06-21 |
Family
ID=18713540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000218617A Pending JP2002029986A (ja) | 2000-07-19 | 2000-07-19 | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2002029986A (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004189663A (ja) * | 2002-12-11 | 2004-07-08 | Ichimaru Pharcos Co Ltd | メイラード反応阻害剤 |
| JP2007137884A (ja) * | 2005-11-17 | 2007-06-07 | Engelhard Lyon Sa | Has2−刺激性植物抽出物 |
| WO2007094384A1 (ja) * | 2006-02-15 | 2007-08-23 | Pola Chemical Industries Inc. | フラバノン誘導体を含む皮膚外用剤 |
| RU2420264C2 (ru) * | 2006-02-15 | 2011-06-10 | Пола Кемикал Индастриз Инк. | Препарат для местного нанесения на кожу, содержащий производное флаванона |
| KR20170133049A (ko) * | 2016-05-25 | 2017-12-05 | 경북대학교 산학협력단 | 물레나물 추출물을 포함하는 화장료 조성물 |
| WO2021242070A1 (ko) * | 2020-05-29 | 2021-12-02 | 주식회사 디알나노 | 피부탄력 증진 또는 피부주름 개선용 광반응성 화장료 조성물 및 이의 제조방법 |
Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0987155A (ja) * | 1995-09-27 | 1997-03-31 | Shiseido Co Ltd | 紫外線吸収剤及びそれを配合した皮膚外用剤 |
| JPH10265361A (ja) * | 1997-03-25 | 1998-10-06 | Tama Seikagaku Kk | 化粧料 |
| JPH10316550A (ja) * | 1997-05-13 | 1998-12-02 | Kao Corp | 化粧料 |
| JPH115727A (ja) * | 1997-06-17 | 1999-01-12 | Pola Chem Ind Inc | 美肌用の化粧料 |
| JPH1112122A (ja) * | 1997-06-20 | 1999-01-19 | Pola Chem Ind Inc | 皮膚改善化粧料 |
| JPH1179968A (ja) * | 1997-09-04 | 1999-03-23 | Kao Corp | 化粧料 |
| JPH11315008A (ja) * | 1998-03-03 | 1999-11-16 | Shiseido Co Ltd | 抗老化剤 |
| JP2000072665A (ja) * | 1998-08-31 | 2000-03-07 | Kikkoman Corp | ヒアルロニダーゼ阻害剤 |
| JP2000159627A (ja) * | 1998-12-01 | 2000-06-13 | Ichimaru Pharcos Co Ltd | エラスターゼ活性阻害剤及び化粧料組成物 |
| JP2000247830A (ja) * | 1999-02-26 | 2000-09-12 | Nagase & Co Ltd | エラスターゼ阻害剤 |
| JP2001081008A (ja) * | 1999-07-15 | 2001-03-27 | Shiseido Co Ltd | 肌あれ防止・改善用皮膚外用剤 |
| JP2001131046A (ja) * | 1999-11-04 | 2001-05-15 | Pola Chem Ind Inc | 過酸化水素消去剤及びこれを含有する化粧料。 |
| JP2001131044A (ja) * | 1999-11-02 | 2001-05-15 | Pola Chem Ind Inc | 老化改善剤の鑑別法及び老化改善剤を含有する皮膚外用剤 |
| JP2001192316A (ja) * | 2000-01-06 | 2001-07-17 | Shiseido Co Ltd | マトリックスメタロプロテアーゼ阻害剤 |
| JP2001226249A (ja) * | 2000-02-17 | 2001-08-21 | Ichimaru Pharcos Co Ltd | 植物水蒸気蒸留水含有化粧料組成物 |
| JP2002003358A (ja) * | 2000-06-23 | 2002-01-09 | Shiseido Co Ltd | 皮膚外用剤 |
-
2000
- 2000-07-19 JP JP2000218617A patent/JP2002029986A/ja active Pending
Patent Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0987155A (ja) * | 1995-09-27 | 1997-03-31 | Shiseido Co Ltd | 紫外線吸収剤及びそれを配合した皮膚外用剤 |
| JPH10265361A (ja) * | 1997-03-25 | 1998-10-06 | Tama Seikagaku Kk | 化粧料 |
| JPH10316550A (ja) * | 1997-05-13 | 1998-12-02 | Kao Corp | 化粧料 |
| JPH115727A (ja) * | 1997-06-17 | 1999-01-12 | Pola Chem Ind Inc | 美肌用の化粧料 |
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