JP2001523093A - β−アミロイドペプチド結合タンパク質及びそれらをコードするポリヌクレオチド - Google Patents

β−アミロイドペプチド結合タンパク質及びそれらをコードするポリヌクレオチド

Info

Publication number
JP2001523093A
JP2001523093A JP54419698A JP54419698A JP2001523093A JP 2001523093 A JP2001523093 A JP 2001523093A JP 54419698 A JP54419698 A JP 54419698A JP 54419698 A JP54419698 A JP 54419698A JP 2001523093 A JP2001523093 A JP 2001523093A
Authority
JP
Japan
Prior art keywords
protein
polynucleotide
amino acid
sequence
bbp1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP54419698A
Other languages
English (en)
Japanese (ja)
Inventor
オーゼンベルガー，ブラドリー・アルトン
カイコウスキ，アイリーン・マリー
ジヤコブセン，ジヤツク・スチーブン
バード，ジヨナサン・アダム
ウオーカー，スチーブン・グレン
Original Assignee
アメリカン・ホーム・プロダクツ・コーポレーシヨン
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アメリカン・ホーム・プロダクツ・コーポレーシヨン filed Critical アメリカン・ホーム・プロダクツ・コーポレーシヨン
Publication of JP2001523093A publication Critical patent/JP2001523093A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP54419698A 1997-04-16 1998-04-14 β−アミロイドペプチド結合タンパク質及びそれらをコードするポリヌクレオチド Pending JP2001523093A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16
US60/064,583 1997-04-16
PCT/US1998/007462 WO1998046636A2 (en) 1997-04-16 1998-04-14 β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2007339660A Division JP2008104465A (ja) 1997-04-16 2007-12-28 β−アミロイドペプチド結合タンパク質及びそれらをコードするポリヌクレオチド
JP2008159606A Division JP2008253275A (ja) 1997-04-16 2008-06-18 β−アミロイドペプチド結合タンパク質及びそれをコードするポリヌクレオチド

Publications (1)

Publication Number Publication Date
JP2001523093A true JP2001523093A (ja) 2001-11-20

Family

ID=22056941

Family Applications (3)

Application Number Title Priority Date Filing Date
JP54419698A Pending JP2001523093A (ja) 1997-04-16 1998-04-14 β−アミロイドペプチド結合タンパク質及びそれらをコードするポリヌクレオチド
JP2007339660A Pending JP2008104465A (ja) 1997-04-16 2007-12-28 β−アミロイドペプチド結合タンパク質及びそれらをコードするポリヌクレオチド
JP2008159606A Pending JP2008253275A (ja) 1997-04-16 2008-06-18 β−アミロイドペプチド結合タンパク質及びそれをコードするポリヌクレオチド

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007339660A Pending JP2008104465A (ja) 1997-04-16 2007-12-28 β−アミロイドペプチド結合タンパク質及びそれらをコードするポリヌクレオチド
JP2008159606A Pending JP2008253275A (ja) 1997-04-16 2008-06-18 β−アミロイドペプチド結合タンパク質及びそれをコードするポリヌクレオチド

Country Status (18)

Country Link
EP (1) EP0975753A2 (enExample)
JP (3) JP2001523093A (enExample)
KR (1) KR20010006393A (enExample)
CN (2) CN1196785C (enExample)
AU (1) AU740445B2 (enExample)
BR (1) BR9808562A (enExample)
CA (1) CA2286484A1 (enExample)
EA (1) EA004256B1 (enExample)
EE (1) EE9900482A (enExample)
GE (1) GEP20043386B (enExample)
HU (1) HUP0003116A3 (enExample)
ID (1) ID24914A (enExample)
IL (3) IL132236A0 (enExample)
NO (1) NO995062L (enExample)
NZ (1) NZ500216A (enExample)
SK (1) SK143299A3 (enExample)
UA (1) UA72875C2 (enExample)
WO (1) WO1998046636A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
US6787319B2 (en) * 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
EP1121432A2 (en) * 1998-10-13 2001-08-08 American Home Products Corporation G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
CA2387646A1 (en) * 1999-10-21 2001-04-26 Kalobios, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
WO2012020124A1 (en) 2010-08-12 2012-02-16 Ac Immune S.A. Vaccine engineering
EP2632434B1 (en) 2010-10-26 2025-08-20 AC Immune S.A. Liposome-based construct comprising a peptide modified through hydrophobic moieties
CN102060912B (zh) * 2010-11-22 2012-11-14 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用
CN111320678B (zh) * 2020-03-09 2023-06-09 安亭生物有限责任公司 抗菌肽突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0779702B2 (ja) * 1986-11-17 1995-08-30 サイオス ノバ インコーポレイテッド 組換えアルツハイマーアミロイドタンパク
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
EA199900941A1 (ru) 2000-06-26
GEP20043386B (en) 2004-02-10
NO995062D0 (no) 1999-10-15
JP2008104465A (ja) 2008-05-08
ID24914A (id) 2000-08-31
WO1998046636A3 (en) 1999-01-28
IL179047A0 (en) 2007-03-08
IL132236A0 (en) 2001-03-19
CA2286484A1 (en) 1998-10-22
JP2008253275A (ja) 2008-10-23
KR20010006393A (ko) 2001-01-26
EP0975753A2 (en) 2000-02-02
WO1998046636A2 (en) 1998-10-22
NZ500216A (en) 2001-06-29
UA72875C2 (uk) 2005-05-16
AU740445B2 (en) 2001-11-01
CN1690203A (zh) 2005-11-02
SK143299A3 (en) 2000-09-12
CN1268973A (zh) 2000-10-04
NO995062L (no) 1999-12-14
HUP0003116A3 (en) 2003-03-28
HUP0003116A2 (hu) 2001-01-29
EA004256B1 (ru) 2004-02-26
IL132236A (en) 2007-03-08
AU7115698A (en) 1998-11-11
CN1196785C (zh) 2005-04-13
EE9900482A (enExample) 2000-06-15
BR9808562A (pt) 2000-05-23

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