WO1998046636A3 - β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME - Google Patents
β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME Download PDFInfo
- Publication number
- WO1998046636A3 WO1998046636A3 PCT/US1998/007462 US9807462W WO9846636A3 WO 1998046636 A3 WO1998046636 A3 WO 1998046636A3 US 9807462 W US9807462 W US 9807462W WO 9846636 A3 WO9846636 A3 WO 9846636A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- amyloid peptide
- same
- binding proteins
- polynucleotides encoding
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UA99116193A UA72875C2 (en) | 1997-04-16 | 1998-04-14 | Novel proteins which bind human <sub>0100090000039d00000002001c00000000000500000009020000000005000000020101000000050000000102ffffff00050000002e0118000000050000000b0200000000050000000c02000240011200000026060f001a00ffffffff000010000000c0ffffffc6ffffff00010000c60100000b00000026060f000c004d61746854797065000050001c000000fb0280fe0000000000009001000000020002001053796d626f6c0077400000006b0d0a974c53f5775553f5770100000000003000040000002d01000008000000320a600128000100000062790a00000026060f000a00ffffffff0100000000001c000000fb021000070000000000bc02000000cc0102022253797374656d000000000a000000040000000000ffffffff0100000000003000040000002d01010004000000f0010000030000000000-amyloid peptide, polynucleotides which encode theM |
IL13223698A IL132236A0 (en) | 1997-04-16 | 1998-04-14 | Beta - amyloid peptide - binding proteins and polynucleotides encoding the same |
KR1019997009480A KR20010006393A (en) | 1997-04-16 | 1998-04-14 | β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME |
EA199900941A EA004256B1 (en) | 1997-04-16 | 1998-04-14 | beta-AMINOLOID PEPTIDE BINDING PROTEIN, POLYNUCLEOTIDE ENCODING THEREOF AND METHODS FOR USING THE SAME |
SK1432-99A SK143299A3 (en) | 1997-04-16 | 1998-04-14 | BETA-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDESì (54) ENCODING THE SAME |
NZ500216A NZ500216A (en) | 1997-04-16 | 1998-04-14 | Beta-amyloid peptide-binding proteins and pharmaceutical use |
EP98918186A EP0975753A2 (en) | 1997-04-16 | 1998-04-14 | $g(b)-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME |
BR9808562-0A BR9808562A (en) | 1997-04-16 | 1998-04-14 | Isolated polynucleotide, host cell, protein, oligonucleotide, antibody, processes to produce a protein encoded by the polynucleotide, to determine a polynucleotide that encodes a beta-amyloid peptide-binding protein (bbp) in a sample, to detect in a sample a polypeptide , to diagnose a disease comprising the aberrant expression of human beta-amyloid peptide (bap), to diagnose, to identify compounds that regulate the activity of a beta-amyloid peptide-binding protein and to treat a patient needing to inhibit the accumulation of beta-amyloid peptide in the brain, and, transgenic or chimeric animal. |
AU71156/98A AU740445B2 (en) | 1997-04-16 | 1998-04-14 | Beta-amyloid peptide-binding proteins and polynucleotides encoding the same |
CA002286484A CA2286484A1 (en) | 1997-04-16 | 1998-04-14 | .beta.-amyloid peptide-binding proteins and polynucleotides encoding the same |
EEP199900482A EE9900482A (en) | 1997-04-16 | 1998-04-14 | |
JP54419698A JP2001523093A (en) | 1997-04-16 | 1998-04-14 | β-amyloid peptide binding proteins and polynucleotides encoding them |
IL132236A IL132236A (en) | 1997-04-16 | 1999-10-06 | ??-amyloid peptide binding proteins and polynucleotides encoding the same |
NO995062A NO995062L (en) | 1997-04-16 | 1999-10-15 | <Beta> -anyloid peptide binding proteins and polynuldeotides encoding the same |
IL179047A IL179047A0 (en) | 1997-04-16 | 2006-11-05 | ??-amyloid peptide- binding proteins and polynucleotides encoding the same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6458397P | 1997-04-16 | 1997-04-16 | |
US60/064,583 | 1997-04-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998046636A2 WO1998046636A2 (en) | 1998-10-22 |
WO1998046636A3 true WO1998046636A3 (en) | 1999-01-28 |
Family
ID=22056941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/007462 WO1998046636A2 (en) | 1997-04-16 | 1998-04-14 | β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0975753A2 (en) |
JP (3) | JP2001523093A (en) |
KR (1) | KR20010006393A (en) |
CN (2) | CN1690203A (en) |
AU (1) | AU740445B2 (en) |
BR (1) | BR9808562A (en) |
CA (1) | CA2286484A1 (en) |
EA (1) | EA004256B1 (en) |
EE (1) | EE9900482A (en) |
GE (1) | GEP20043386B (en) |
HU (1) | HUP0003116A3 (en) |
ID (1) | ID24914A (en) |
IL (3) | IL132236A0 (en) |
NO (1) | NO995062L (en) |
NZ (1) | NZ500216A (en) |
SK (1) | SK143299A3 (en) |
UA (1) | UA72875C2 (en) |
WO (1) | WO1998046636A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6787319B2 (en) | 1997-04-16 | 2004-09-07 | American Home Products Corp. | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
US7005295B1 (en) | 1997-04-16 | 2006-02-28 | Wyeth | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
CA2346008A1 (en) * | 1998-10-13 | 2000-04-20 | American Home Products Corporation | G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same |
US6455082B1 (en) * | 1999-04-26 | 2002-09-24 | Nestec S.A. | Shelf-stable calcium fortified milk and dairy products |
WO2001029225A1 (en) * | 1999-10-21 | 2001-04-26 | Panorama Research, Inc. | A general method for optimizing the expression of heterologous proteins |
US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
US7807171B2 (en) | 2003-07-25 | 2010-10-05 | Ac Immune Sa | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
WO2012020124A1 (en) | 2010-08-12 | 2012-02-16 | Ac Immune S.A. | Vaccine engineering |
CN103189050B (en) | 2010-10-26 | 2017-09-29 | Ac免疫有限公司 | The construct based on liposome comprising the peptide modified by hydrophobic part |
CN102060912B (en) * | 2010-11-22 | 2012-11-14 | 清华大学 | Amyloid protein oligomer conformation type epitope polypeptide and application thereof |
CN111320678B (en) * | 2020-03-09 | 2023-06-09 | 安亭生物有限责任公司 | Antibacterial peptide mutant and application thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988003951A1 (en) * | 1986-11-17 | 1988-06-02 | California Biotechnology, Inc. | Recombinant alzheimer's amyloid protein |
WO1996013513A1 (en) * | 1994-10-28 | 1996-05-09 | American National Red Cross | Alzheimer's peptide |
WO1996025435A1 (en) * | 1995-02-14 | 1996-08-22 | Bayer Corporation | MONOCLONAL ANTIBODY SPECIFIC FOR βA4 PEPTIDE |
-
1998
- 1998-04-14 EE EEP199900482A patent/EE9900482A/xx unknown
- 1998-04-14 EA EA199900941A patent/EA004256B1/en not_active IP Right Cessation
- 1998-04-14 ID IDW991187D patent/ID24914A/en unknown
- 1998-04-14 KR KR1019997009480A patent/KR20010006393A/en not_active Application Discontinuation
- 1998-04-14 BR BR9808562-0A patent/BR9808562A/en not_active Application Discontinuation
- 1998-04-14 EP EP98918186A patent/EP0975753A2/en not_active Withdrawn
- 1998-04-14 HU HU0003116A patent/HUP0003116A3/en unknown
- 1998-04-14 JP JP54419698A patent/JP2001523093A/en active Pending
- 1998-04-14 UA UA99116193A patent/UA72875C2/en unknown
- 1998-04-14 NZ NZ500216A patent/NZ500216A/en unknown
- 1998-04-14 GE GE3744A patent/GEP20043386B/en unknown
- 1998-04-14 SK SK1432-99A patent/SK143299A3/en unknown
- 1998-04-14 CN CNA200510052975XA patent/CN1690203A/en active Pending
- 1998-04-14 IL IL13223698A patent/IL132236A0/en active IP Right Grant
- 1998-04-14 AU AU71156/98A patent/AU740445B2/en not_active Ceased
- 1998-04-14 CA CA002286484A patent/CA2286484A1/en not_active Abandoned
- 1998-04-14 CN CNB988043173A patent/CN1196785C/en not_active Expired - Fee Related
- 1998-04-14 WO PCT/US1998/007462 patent/WO1998046636A2/en active Application Filing
-
1999
- 1999-10-06 IL IL132236A patent/IL132236A/en not_active IP Right Cessation
- 1999-10-15 NO NO995062A patent/NO995062L/en not_active Application Discontinuation
-
2006
- 2006-11-05 IL IL179047A patent/IL179047A0/en unknown
-
2007
- 2007-12-28 JP JP2007339660A patent/JP2008104465A/en active Pending
-
2008
- 2008-06-18 JP JP2008159606A patent/JP2008253275A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988003951A1 (en) * | 1986-11-17 | 1988-06-02 | California Biotechnology, Inc. | Recombinant alzheimer's amyloid protein |
WO1996013513A1 (en) * | 1994-10-28 | 1996-05-09 | American National Red Cross | Alzheimer's peptide |
WO1996025435A1 (en) * | 1995-02-14 | 1996-08-22 | Bayer Corporation | MONOCLONAL ANTIBODY SPECIFIC FOR βA4 PEPTIDE |
Non-Patent Citations (5)
Title |
---|
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, - 10 May 1996 (1996-05-10), HINXTON, GB, XP002081598 * |
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 22 July 1998 (1998-07-22), HINXTON, GB, XP002081601 * |
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 31 January 1998 (1998-01-31), HINXTON, GB, XP002081600 * |
L.O. TJERNBERG ET AL.,: "Arrest of beta-amyloid fibril formation by a peptapeptide ligand", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 15, 1996, BETHESDA, MD, US, pages 8545 - 8548, XP002050226 * |
T. YAMATSUJI ET AL.,: "G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP", SCIENCE, vol. 272, 1996, WASHINGTON, DC, US, pages 1349 - 1352, XP002081599 * |
Also Published As
Publication number | Publication date |
---|---|
SK143299A3 (en) | 2000-09-12 |
CN1268973A (en) | 2000-10-04 |
AU740445B2 (en) | 2001-11-01 |
WO1998046636A2 (en) | 1998-10-22 |
JP2001523093A (en) | 2001-11-20 |
IL132236A0 (en) | 2001-03-19 |
GEP20043386B (en) | 2004-02-10 |
NO995062L (en) | 1999-12-14 |
KR20010006393A (en) | 2001-01-26 |
HUP0003116A2 (en) | 2001-01-29 |
IL132236A (en) | 2007-03-08 |
JP2008253275A (en) | 2008-10-23 |
EP0975753A2 (en) | 2000-02-02 |
CN1690203A (en) | 2005-11-02 |
ID24914A (en) | 2000-08-31 |
UA72875C2 (en) | 2005-05-16 |
NZ500216A (en) | 2001-06-29 |
EA199900941A1 (en) | 2000-06-26 |
IL179047A0 (en) | 2007-03-08 |
EA004256B1 (en) | 2004-02-26 |
CA2286484A1 (en) | 1998-10-22 |
HUP0003116A3 (en) | 2003-03-28 |
NO995062D0 (en) | 1999-10-15 |
EE9900482A (en) | 2000-06-15 |
BR9808562A (en) | 2000-05-23 |
CN1196785C (en) | 2005-04-13 |
JP2008104465A (en) | 2008-05-08 |
AU7115698A (en) | 1998-11-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2002090499A3 (en) | ss-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME | |
EP0832973A3 (en) | GTP-binding protein | |
WO1998031799A3 (en) | Polynucleotides and polypeptides encoding receptors | |
WO2002002604A3 (en) | Leucine-rich repeat proteins, zlrr7, zlrr8 and zlrr9 | |
WO1999058562A3 (en) | Novel compounds | |
WO1999060017A3 (en) | Human tumour-derived polypeptide hormone phosphatonin | |
WO1998046636A3 (en) | β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME | |
GB9810276D0 (en) | Novel compounds | |
WO2000053742A3 (en) | Polynucleotides and proteins encoded thereby | |
WO2001077289A3 (en) | Polynucleotides encoding novel secreted proteins | |
WO2001077288A3 (en) | Polynucleotides encoding novel secreted proteins | |
GB9820003D0 (en) | Novel compounds | |
EP0885959A3 (en) | Human Wnt-5b protein | |
WO2000061754A3 (en) | Human proteins and polynucleotides encoding them | |
GB9809683D0 (en) | Novel compounds | |
WO2001032878A3 (en) | A novel polypeptide hormone phosphatonin | |
WO1999064448A3 (en) | Moraxella catarrhalis pilq proteins | |
GB9810285D0 (en) | Novel compounds | |
WO2000070046A3 (en) | Secreted polypeptides and corresponding polynucleotides | |
WO1999038885A3 (en) | Sbsemvl polypeptides, being members of the semaphorin protein family, and polynucleotides encoding the same | |
GB9812440D0 (en) | Novel compounds | |
WO2002030971A3 (en) | Basb205 polypeptides and polynucleotides coding therefor | |
EP0863152A3 (en) | Streptococcus pneumoniae Def1 protein | |
WO2000022125A3 (en) | 6-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same | |
WO2000042165A3 (en) | Bone marrow-specific protein |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 132236 Country of ref document: IL Ref document number: 98804317.3 Country of ref document: CN |
|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 500216 Country of ref document: NZ |
|
WWE | Wipo information: entry into national phase |
Ref document number: PV1999-3612 Country of ref document: CZ |
|
ENP | Entry into the national phase |
Ref document number: 2286484 Country of ref document: CA Ref document number: 2286484 Country of ref document: CA Kind code of ref document: A Ref document number: 1998 544196 Country of ref document: JP Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: 71156/98 Country of ref document: AU Ref document number: 1019997009480 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/1999/009493 Country of ref document: MX Ref document number: 143299 Country of ref document: SK |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1998918186 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 5080/1 Country of ref document: GE Ref document number: 199900941 Country of ref document: EA |
|
WWP | Wipo information: published in national office |
Ref document number: 1998918186 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWP | Wipo information: published in national office |
Ref document number: PV1999-3612 Country of ref document: CZ |
|
WWP | Wipo information: published in national office |
Ref document number: 1019997009480 Country of ref document: KR |
|
WWG | Wipo information: grant in national office |
Ref document number: 71156/98 Country of ref document: AU |
|
WWR | Wipo information: refused in national office |
Ref document number: 1019997009480 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 179047 Country of ref document: IL |