EA199900941A1 - PROTEINS CONNECTING WITH β-AMYLOID PEPTIDE AND ENCODING THEIR POLYNUCLEOTIDE - Google Patents

PROTEINS CONNECTING WITH β-AMYLOID PEPTIDE AND ENCODING THEIR POLYNUCLEOTIDE

Info

Publication number
EA199900941A1
EA199900941A1 EA199900941A EA199900941A EA199900941A1 EA 199900941 A1 EA199900941 A1 EA 199900941A1 EA 199900941 A EA199900941 A EA 199900941A EA 199900941 A EA199900941 A EA 199900941A EA 199900941 A1 EA199900941 A1 EA 199900941A1
Authority
EA
Eurasian Patent Office
Prior art keywords
proteins
amyloid peptide
polynucleotide
encoding
proteins connecting
Prior art date
Application number
EA199900941A
Other languages
Russian (ru)
Other versions
EA004256B1 (en
Inventor
Бредли Элтон Озенбергер
Эйлин Мари Кажковски
Джек Стивен Джекобсен
Джонатан Адам Бард
Стефен Гленн Волкер
Original Assignee
Американ Хоум Продактс Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Американ Хоум Продактс Корпорейшн filed Critical Американ Хоум Продактс Корпорейшн
Publication of EA199900941A1 publication Critical patent/EA199900941A1/en
Publication of EA004256B1 publication Critical patent/EA004256B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Представлены новые белки, которые связываются с β-амилоидным пептидом человека, полинуклеотиды, которые кодируют эти белки, и способы получения этих белков. Также представлены диагностические и терапевтические способы и способы скрининга с использованием полинуклеотидов и полипептидов по настоящему изобретению.Отчет о международном поиске был опубликован 1999.01.28New proteins that bind to human β-amyloid peptide, polynucleotides that encode these proteins, and methods for producing these proteins are presented. Diagnostic and therapeutic methods and screening methods using the polynucleotides and polypeptides of the present invention are also presented. An international search report was published 1999.01.28

EA199900941A 1997-04-16 1998-04-14 beta-AMINOLOID PEPTIDE BINDING PROTEIN, POLYNUCLEOTIDE ENCODING THEREOF AND METHODS FOR USING THE SAME EA004256B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16
PCT/US1998/007462 WO1998046636A2 (en) 1997-04-16 1998-04-14 β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME

Publications (2)

Publication Number Publication Date
EA199900941A1 true EA199900941A1 (en) 2000-06-26
EA004256B1 EA004256B1 (en) 2004-02-26

Family

ID=22056941

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900941A EA004256B1 (en) 1997-04-16 1998-04-14 beta-AMINOLOID PEPTIDE BINDING PROTEIN, POLYNUCLEOTIDE ENCODING THEREOF AND METHODS FOR USING THE SAME

Country Status (18)

Country Link
EP (1) EP0975753A2 (en)
JP (3) JP2001523093A (en)
KR (1) KR20010006393A (en)
CN (2) CN1196785C (en)
AU (1) AU740445B2 (en)
BR (1) BR9808562A (en)
CA (1) CA2286484A1 (en)
EA (1) EA004256B1 (en)
EE (1) EE9900482A (en)
GE (1) GEP20043386B (en)
HU (1) HUP0003116A3 (en)
ID (1) ID24914A (en)
IL (3) IL132236A0 (en)
NO (1) NO995062L (en)
NZ (1) NZ500216A (en)
SK (1) SK143299A3 (en)
UA (1) UA72875C2 (en)
WO (1) WO1998046636A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787319B2 (en) * 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
EP1121432A2 (en) * 1998-10-13 2001-08-08 American Home Products Corporation G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
WO2001029225A1 (en) * 1999-10-21 2001-04-26 Panorama Research, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
WO2012020124A1 (en) 2010-08-12 2012-02-16 Ac Immune S.A. Vaccine engineering
AR083561A1 (en) 2010-10-26 2013-03-06 Ac Immune Sa PREPARATION OF AN ANTIGENIC CONSTRUCTION
CN102060912B (en) * 2010-11-22 2012-11-14 清华大学 Amyloid protein oligomer conformation type epitope polypeptide and application thereof
CN111320678B (en) * 2020-03-09 2023-06-09 安亭生物有限责任公司 Antibacterial peptide mutant and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0332640A1 (en) * 1986-11-17 1989-09-20 California Biotechnology, Inc. Recombinant alzheimer's amyloid protein
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
WO1998046636A3 (en) 1999-01-28
JP2001523093A (en) 2001-11-20
NO995062L (en) 1999-12-14
SK143299A3 (en) 2000-09-12
AU7115698A (en) 1998-11-11
GEP20043386B (en) 2004-02-10
EE9900482A (en) 2000-06-15
CA2286484A1 (en) 1998-10-22
CN1196785C (en) 2005-04-13
AU740445B2 (en) 2001-11-01
JP2008253275A (en) 2008-10-23
JP2008104465A (en) 2008-05-08
KR20010006393A (en) 2001-01-26
CN1268973A (en) 2000-10-04
EA004256B1 (en) 2004-02-26
UA72875C2 (en) 2005-05-16
NZ500216A (en) 2001-06-29
IL179047A0 (en) 2007-03-08
EP0975753A2 (en) 2000-02-02
CN1690203A (en) 2005-11-02
NO995062D0 (en) 1999-10-15
IL132236A0 (en) 2001-03-19
IL132236A (en) 2007-03-08
HUP0003116A2 (en) 2001-01-29
HUP0003116A3 (en) 2003-03-28
ID24914A (en) 2000-08-31
WO1998046636A2 (en) 1998-10-22
BR9808562A (en) 2000-05-23

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU