CN1196785C - β－淀粉样肽结合蛋白及其编码聚核苷酸 - Google Patents

β－淀粉样肽结合蛋白及其编码聚核苷酸 Download PDF

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Publication number
CN1196785C
CN1196785C CNB988043173A CN98804317A CN1196785C CN 1196785 C CN1196785 C CN 1196785C CN B988043173 A CNB988043173 A CN B988043173A CN 98804317 A CN98804317 A CN 98804317A CN 1196785 C CN1196785 C CN 1196785C
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China
Prior art keywords
protein
bbp
sequence
polynucleotide
bap
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Expired - Fee Related
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CNB988043173A
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English (en)
Chinese (zh)
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CN1268973A (zh
Inventor
B·A·奥藏伯格
J·A·巴德
E·M·卡科斯基
J·S·雅各布森
S·G·沃克
H·索菲亚
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Wyeth LLC
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Wyeth LLC
American Home Products Corp
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Publication of CN1268973A publication Critical patent/CN1268973A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNB988043173A 1997-04-16 1998-04-14 β－淀粉样肽结合蛋白及其编码聚核苷酸 Expired - Fee Related CN1196785C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16
US60/064,583 1997-04-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA200510052975XA Division CN1690203A (zh) 1997-04-16 1998-04-14 β－淀粉样肽结合蛋白及其编码聚核苷酸

Publications (2)

Publication Number Publication Date
CN1268973A CN1268973A (zh) 2000-10-04
CN1196785C true CN1196785C (zh) 2005-04-13

Family

ID=22056941

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB988043173A Expired - Fee Related CN1196785C (zh) 1997-04-16 1998-04-14 β－淀粉样肽结合蛋白及其编码聚核苷酸
CNA200510052975XA Pending CN1690203A (zh) 1997-04-16 1998-04-14 β－淀粉样肽结合蛋白及其编码聚核苷酸

Family Applications After (1)

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CNA200510052975XA Pending CN1690203A (zh) 1997-04-16 1998-04-14 β－淀粉样肽结合蛋白及其编码聚核苷酸

Country Status (18)

Country Link
EP (1) EP0975753A2 (enExample)
JP (3) JP2001523093A (enExample)
KR (1) KR20010006393A (enExample)
CN (2) CN1196785C (enExample)
AU (1) AU740445B2 (enExample)
BR (1) BR9808562A (enExample)
CA (1) CA2286484A1 (enExample)
EA (1) EA004256B1 (enExample)
EE (1) EE9900482A (enExample)
GE (1) GEP20043386B (enExample)
HU (1) HUP0003116A3 (enExample)
ID (1) ID24914A (enExample)
IL (3) IL132236A0 (enExample)
NO (1) NO995062L (enExample)
NZ (1) NZ500216A (enExample)
SK (1) SK143299A3 (enExample)
UA (1) UA72875C2 (enExample)
WO (1) WO1998046636A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
US6787319B2 (en) 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
NZ510997A (en) * 1998-10-13 2004-01-30 Wyeth Corp G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
EP1226241A1 (en) * 1999-10-21 2002-07-31 Panorama Research, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
EP3527220A1 (en) 2010-08-12 2019-08-21 AC Immune S.A. Vaccine engineering
EP2632434B1 (en) 2010-10-26 2025-08-20 AC Immune S.A. Liposome-based construct comprising a peptide modified through hydrophobic moieties
CN102060912B (zh) * 2010-11-22 2012-11-14 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用
CN111320678B (zh) * 2020-03-09 2023-06-09 安亭生物有限责任公司 抗菌肽突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611122B2 (en) * 1986-11-17 1991-06-06 Scios Nova Inc. Recombinant alzheimer's amyloid protein
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
CN1690203A (zh) 2005-11-02
NO995062L (no) 1999-12-14
NZ500216A (en) 2001-06-29
IL179047A0 (en) 2007-03-08
KR20010006393A (ko) 2001-01-26
GEP20043386B (en) 2004-02-10
SK143299A3 (en) 2000-09-12
WO1998046636A2 (en) 1998-10-22
WO1998046636A3 (en) 1999-01-28
AU7115698A (en) 1998-11-11
HUP0003116A3 (en) 2003-03-28
JP2008253275A (ja) 2008-10-23
EP0975753A2 (en) 2000-02-02
IL132236A (en) 2007-03-08
CN1268973A (zh) 2000-10-04
BR9808562A (pt) 2000-05-23
EA004256B1 (ru) 2004-02-26
ID24914A (id) 2000-08-31
AU740445B2 (en) 2001-11-01
EA199900941A1 (ru) 2000-06-26
HUP0003116A2 (hu) 2001-01-29
UA72875C2 (uk) 2005-05-16
CA2286484A1 (en) 1998-10-22
IL132236A0 (en) 2001-03-19
JP2001523093A (ja) 2001-11-20
JP2008104465A (ja) 2008-05-08
EE9900482A (enExample) 2000-06-15
NO995062D0 (no) 1999-10-15

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Granted publication date: 20050413