HUP0003116A2 - Béta-amiloid-peptid-kötő fehérjék és az őket kódoló polinukleotidok - Google Patents

Béta-amiloid-peptid-kötő fehérjék és az őket kódoló polinukleotidok

Info

Publication number
HUP0003116A2
HUP0003116A2 HU0003116A HUP0003116A HUP0003116A2 HU P0003116 A2 HUP0003116 A2 HU P0003116A2 HU 0003116 A HU0003116 A HU 0003116A HU P0003116 A HUP0003116 A HU P0003116A HU P0003116 A2 HUP0003116 A2 HU P0003116A2
Authority
HU
Hungary
Prior art keywords
amyloid peptide
proteins
betha
same
subject
Prior art date
Application number
HU0003116A
Other languages
English (en)
Inventor
Jonathan Adam Bard
Jack Steven Jacobsen
Eileen Marie Kajkowski
Bradley Alton Ozenberger
Stephen Glenn Walker
Original Assignee
American Home Products Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corporation filed Critical American Home Products Corporation
Publication of HUP0003116A2 publication Critical patent/HUP0003116A2/hu
Publication of HUP0003116A3 publication Critical patent/HUP0003116A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Atalálmány tárgyát b-amiloidpeptidhez kötődő új polinukleotidok és azáltaluk kódolt fehérjék, a fehérjéket vagy részeiket kódoló fúziósfehérjék és a hozzájuk kötődő antitestek képezik, továbbá eljárásokezek előállítására. Atalálmány tárgyát képezik továbbá a találmányszerinti polinukleotidokkal transzformált gazdasejtek és az azokattartalmazó transzgenikus állatok. Atalálmány tárgyát képezik továbbáeljárások a fehérjék és a nukleotidok terápiás, diagnosztikai éskutatási célokra való alkalmazására. A találmány szerinti megoldásAlzheimer-kór kezelésében, diagnózisában, továbbá az ezzel a kórralkapcsolatos kutatások területén alkalmazható. Ó
HU0003116A 1997-04-16 1998-04-14 Betha-amyloid peptide-binding proteins and polynucleotides encoding the same HUP0003116A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16

Publications (2)

Publication Number Publication Date
HUP0003116A2 true HUP0003116A2 (hu) 2001-01-29
HUP0003116A3 HUP0003116A3 (en) 2003-03-28

Family

ID=22056941

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003116A HUP0003116A3 (en) 1997-04-16 1998-04-14 Betha-amyloid peptide-binding proteins and polynucleotides encoding the same

Country Status (18)

Country Link
EP (1) EP0975753A2 (hu)
JP (3) JP2001523093A (hu)
KR (1) KR20010006393A (hu)
CN (2) CN1690203A (hu)
AU (1) AU740445B2 (hu)
BR (1) BR9808562A (hu)
CA (1) CA2286484A1 (hu)
EA (1) EA004256B1 (hu)
EE (1) EE9900482A (hu)
GE (1) GEP20043386B (hu)
HU (1) HUP0003116A3 (hu)
ID (1) ID24914A (hu)
IL (3) IL132236A0 (hu)
NO (1) NO995062L (hu)
NZ (1) NZ500216A (hu)
SK (1) SK143299A3 (hu)
UA (1) UA72875C2 (hu)
WO (1) WO1998046636A2 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787319B2 (en) 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
CA2346008A1 (en) * 1998-10-13 2000-04-20 American Home Products Corporation G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
WO2001029225A1 (en) * 1999-10-21 2001-04-26 Panorama Research, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
WO2012020124A1 (en) 2010-08-12 2012-02-16 Ac Immune S.A. Vaccine engineering
CN103189050B (zh) 2010-10-26 2017-09-29 Ac免疫有限公司 包含通过疏水部分修饰的肽的基于脂质体的构建体
CN102060912B (zh) * 2010-11-22 2012-11-14 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用
CN111320678B (zh) * 2020-03-09 2023-06-09 安亭生物有限责任公司 抗菌肽突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0332640A1 (en) * 1986-11-17 1989-09-20 California Biotechnology, Inc. Recombinant alzheimer's amyloid protein
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
SK143299A3 (en) 2000-09-12
CN1268973A (zh) 2000-10-04
AU740445B2 (en) 2001-11-01
WO1998046636A2 (en) 1998-10-22
JP2001523093A (ja) 2001-11-20
IL132236A0 (en) 2001-03-19
GEP20043386B (en) 2004-02-10
NO995062L (no) 1999-12-14
KR20010006393A (ko) 2001-01-26
IL132236A (en) 2007-03-08
JP2008253275A (ja) 2008-10-23
EP0975753A2 (en) 2000-02-02
CN1690203A (zh) 2005-11-02
ID24914A (id) 2000-08-31
UA72875C2 (uk) 2005-05-16
NZ500216A (en) 2001-06-29
EA199900941A1 (ru) 2000-06-26
IL179047A0 (en) 2007-03-08
EA004256B1 (ru) 2004-02-26
CA2286484A1 (en) 1998-10-22
HUP0003116A3 (en) 2003-03-28
NO995062D0 (no) 1999-10-15
EE9900482A (hu) 2000-06-15
WO1998046636A3 (en) 1999-01-28
BR9808562A (pt) 2000-05-23
CN1196785C (zh) 2005-04-13
JP2008104465A (ja) 2008-05-08
AU7115698A (en) 1998-11-11

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees
HA9A Change in inventorship