JP2001520985A5 - - Google Patents
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- Publication number
- JP2001520985A5 JP2001520985A5 JP2000517695A JP2000517695A JP2001520985A5 JP 2001520985 A5 JP2001520985 A5 JP 2001520985A5 JP 2000517695 A JP2000517695 A JP 2000517695A JP 2000517695 A JP2000517695 A JP 2000517695A JP 2001520985 A5 JP2001520985 A5 JP 2001520985A5
- Authority
- JP
- Japan
- Prior art keywords
- weight
- core
- drug release
- release system
- osmotic drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 4
- 230000003204 osmotic effect Effects 0.000 description 4
- 239000000306 component Substances 0.000 description 3
- 239000000654 additive Substances 0.000 description 2
- 239000008358 core component Substances 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000012902 Nervous system disease Diseases 0.000 description 1
- 208000032851 Subarachnoid Hemorrhage Diseases 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000007971 neurological deficit Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19747261.3 | 1997-10-25 | ||
| DE19747261A DE19747261A1 (de) | 1997-10-25 | 1997-10-25 | Osmotisches Arzneimittelfreisetzungssystem |
| PCT/EP1998/006454 WO1999021535A1 (de) | 1997-10-25 | 1998-10-12 | Osmotisches arzneimittelfreisetzungssystem |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001520985A JP2001520985A (ja) | 2001-11-06 |
| JP2001520985A5 true JP2001520985A5 (https=) | 2006-01-05 |
| JP4295916B2 JP4295916B2 (ja) | 2009-07-15 |
Family
ID=7846661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000517695A Expired - Lifetime JP4295916B2 (ja) | 1997-10-25 | 1998-10-12 | 浸透圧性薬剤放出系 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6294201B1 (https=) |
| EP (1) | EP1024793B1 (https=) |
| JP (1) | JP4295916B2 (https=) |
| AT (1) | ATE211907T1 (https=) |
| AU (1) | AU1227899A (https=) |
| CA (1) | CA2307018C (https=) |
| DE (2) | DE19747261A1 (https=) |
| ES (1) | ES2172239T3 (https=) |
| WO (1) | WO1999021535A1 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| US6419954B1 (en) * | 2000-05-19 | 2002-07-16 | Yamanouchi Pharmaceutical Co., Ltd. | Tablets and methods for modified release of hydrophilic and other active agents |
| US20030086972A1 (en) * | 2000-08-09 | 2003-05-08 | Appel Leah E. | Hydrogel-driven drug dosage form |
| DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| JP2005525299A (ja) * | 2001-09-14 | 2005-08-25 | スコラー インコーポレイテッド | アミノ酸調節性の長期放出投薬形態 |
| DE60223695T2 (de) * | 2001-09-14 | 2008-10-30 | Scolr, Inc., Redmond | Aminosäure-modulierte dosierform mit verlängerter freisetzung |
| US6572889B1 (en) | 2002-03-07 | 2003-06-03 | Noveon Ip Holdings Corp. | Controlled release solid dosage carbamazepine formulations |
| SK286107B6 (sk) * | 2002-04-12 | 2008-03-05 | Zentiva, A. S. | Analgeticky účinný perorálny liečivý prípravok s kontrolovaným uvoľňovaním opioidnej účinnej látky a spôsob jeho prípravy |
| WO2003096968A2 (en) * | 2002-05-15 | 2003-11-27 | Sun Pharmaceutical Industries Limited | Oral osmotic controlled drug delivery system |
| US20070077301A1 (en) * | 2002-12-23 | 2007-04-05 | Meyer Glenn A | Venlafaxine osmotic device formulation |
| US8293799B2 (en) * | 2003-12-29 | 2012-10-23 | Osmotica Keresleedelmo és Szolgáltató KFT | Osmotic device containing a venlafaxine salt and a salt having an ion in common |
| DE10300111A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| US20050042289A1 (en) * | 2003-04-29 | 2005-02-24 | Yamanouchi Pharma Technologies, Inc. | Tablets and methods for modified release of hydrophylic and other active agents |
| DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| AR053986A1 (es) | 2004-12-03 | 2007-05-30 | Osmotica Pharmaceutical Argent | Dispositivo osmotico que contiene amantadina y una sal osmotica |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| EP1685841A1 (en) * | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
| JP2008539240A (ja) * | 2005-04-25 | 2008-11-13 | テバ ファーマシュ−ティカルズ ユーエスエー, インコーポレイテッド | 持続放出性処方物 |
| US20070071819A1 (en) * | 2005-05-30 | 2007-03-29 | Kesarwani Amit K | Multiple unit modified release compositions of carbamazepine and process for their preparation |
| DE102005031577A1 (de) * | 2005-07-06 | 2007-01-11 | Bayer Healthcare Ag | Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten |
| DE102005045518A1 (de) | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| US20090099031A1 (en) * | 2005-09-27 | 2009-04-16 | Stemmer Willem P | Genetic package and uses thereof |
| JP2009509535A (ja) * | 2005-09-27 | 2009-03-12 | アムニクス, インコーポレイテッド | タンパク様薬剤およびその使用 |
| US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| US7846445B2 (en) * | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
| CA2624310C (en) | 2005-10-04 | 2014-01-07 | Bayer Healthcare Ag | Polymorphic form of 5-chloro-n-({5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| DE102005047558A1 (de) * | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
| ES2530526T3 (es) | 2005-12-30 | 2015-03-03 | Zensun Shanghai Science And Technology Ltd | Liberación extendida de neurregulina para mejorar la función cardíaca |
| DE102006051625A1 (de) * | 2006-11-02 | 2008-05-08 | Bayer Materialscience Ag | Kombinationstherapie substituierter Oxazolidinone |
| JP2010536341A (ja) * | 2007-08-15 | 2010-12-02 | アムニクス, インコーポレイテッド | 生物学的に活性なポリペプチドの特性を改変するための組成物および方法 |
| DE102008059206A1 (de) * | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
| ES2610356T3 (es) | 2009-02-03 | 2017-04-27 | Amunix Operating Inc. | Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos |
| KR101813727B1 (ko) | 2009-06-08 | 2018-01-02 | 아뮤닉스 오퍼레이팅 인코포레이티드 | 성장 호르몬 폴리펩타이드 및 이를 제조하고 사용하는 방법 |
| WO2010144508A1 (en) | 2009-06-08 | 2010-12-16 | Amunix Operating Inc. | Glucose-regulating polypeptides and methods of making and using same |
| CA2771999A1 (en) | 2009-08-24 | 2011-03-10 | Amunix Operating Inc. | Coagulation factor vii compositions and methods of making and using same |
| DE102011007272A1 (de) | 2011-04-13 | 2012-10-18 | Bayer Pharma Aktiengesellschaft | Verzweigte 3-Phenylpropionsäure-Derivate und ihre Verwendung |
| EP2822577B1 (en) | 2012-02-15 | 2019-02-06 | Bioverativ Therapeutics Inc. | Recombinant factor viii proteins |
| JP6256882B2 (ja) | 2012-02-15 | 2018-01-10 | アムニクス オペレーティング インコーポレイテッド | 第viii因子組成物、ならびに組成物の作製方法および用途 |
| IN2014DN09045A (https=) | 2012-05-07 | 2015-05-22 | Bayer Pharma AG | |
| UY34856A (es) | 2012-07-03 | 2013-12-31 | Bayer Pharma AG | Formas de presentación farmacéuticas que contienen 5-cloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4- morfolinil)-fenil]-1,3-oxazolidin-5-il}-metil)-2-tiofencarboxamida |
| TW202003554A (zh) | 2013-08-14 | 2020-01-16 | 美商百歐維拉提夫治療公司 | 因子viii-xten融合物及其用途 |
| EA201890423A1 (ru) | 2015-08-03 | 2018-07-31 | Биовератив Терапьютикс Инк. | Слитые белки фактора ix, способы их получения и применения |
| MX2019006444A (es) | 2016-12-02 | 2019-10-30 | Bioverativ Therapeutics Inc | Métodos de tratamiento de artropatía hemofílica utilizando factores de coagulación quiméricos. |
| PL3793588T3 (pl) | 2018-05-18 | 2025-09-01 | Bioverativ Therapeutics Inc. | Sposoby leczenia hemofilii a |
| US10905667B2 (en) | 2018-07-24 | 2021-02-02 | Bayer Pharma Aktiengesellschaft | Orally administrable modified-release pharmaceutical dosage form |
| UY38308A (es) | 2018-07-24 | 2020-02-28 | Bayer Pharma AG | Forma de dosificación farmacéutica administrable por vía oral con liberación modificada |
| CN112469398A (zh) * | 2018-07-24 | 2021-03-09 | 拜耳公司 | 可口服给药并具有缓释作用的药物剂型 |
| KR20230041711A (ko) | 2020-06-25 | 2023-03-24 | 아뮤닉스 파마슈티컬스, 인크. | Her-2 표적화 이중특이적 조성물 및 이의 제조 및 사용 방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU466503B2 (en) * | 1972-06-05 | 1975-10-30 | Alza Corporation | Osmotic dispenser |
| USRE34990E (en) * | 1986-08-07 | 1995-07-04 | Ciba-Geigy Corporation | Oral therapeutic system having systemic action |
| EP0277092B1 (de) * | 1987-01-14 | 1992-01-29 | Ciba-Geigy Ag | Therapeutisches System für schwerlösliche Wirkstoffe |
| DE3720757A1 (de) * | 1987-06-24 | 1989-01-05 | Bayer Ag | Dhp-manteltablette |
| NO883326L (no) * | 1987-08-11 | 1989-02-13 | Bayer Ag | Dhp-retard-tilberedning. |
| US4816263A (en) * | 1987-10-02 | 1989-03-28 | Alza Corporation | Dosage form for treating cardiovascular diseases comprising isradipine |
| US5156850A (en) * | 1990-08-31 | 1992-10-20 | Alza Corporation | Dosage form for time-varying patterns of drug delivery |
| US5178867A (en) * | 1991-08-19 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug in short-time period |
| US5240713A (en) * | 1991-09-27 | 1993-08-31 | Alza Corporation | Dual rate agent delivery device |
| US5773025A (en) | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
| US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| DE19515972A1 (de) | 1995-05-02 | 1996-11-07 | Bayer Ag | Arzneizubereitungen mit kontrollierter Freisetzung und Verfahren zu ihrer Herstellung |
| US5654005A (en) * | 1995-06-07 | 1997-08-05 | Andrx Pharmaceuticals, Inc. | Controlled release formulation having a preformed passageway |
-
1997
- 1997-10-25 DE DE19747261A patent/DE19747261A1/de not_active Withdrawn
-
1998
- 1998-10-12 AT AT98955434T patent/ATE211907T1/de not_active IP Right Cessation
- 1998-10-12 JP JP2000517695A patent/JP4295916B2/ja not_active Expired - Lifetime
- 1998-10-12 ES ES98955434T patent/ES2172239T3/es not_active Expired - Lifetime
- 1998-10-12 AU AU12278/99A patent/AU1227899A/en not_active Abandoned
- 1998-10-12 WO PCT/EP1998/006454 patent/WO1999021535A1/de not_active Ceased
- 1998-10-12 CA CA002307018A patent/CA2307018C/en not_active Expired - Lifetime
- 1998-10-12 US US09/530,158 patent/US6294201B1/en not_active Expired - Lifetime
- 1998-10-12 DE DE59802670T patent/DE59802670D1/de not_active Expired - Lifetime
- 1998-10-12 EP EP98955434A patent/EP1024793B1/de not_active Expired - Lifetime
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