|
US5741908A
(en)
|
1996-06-21 |
1998-04-21 |
Minnesota Mining And Manufacturing Company |
Process for reparing imidazoquinolinamines
|
|
EP0938315B9
(en)
|
1996-10-25 |
2008-02-20 |
Minnesota Mining And Manufacturing Company |
Immune response modifier compounds for treatment of th2 mediated and related diseases
|
|
US20060002959A1
(en)
*
|
1996-11-14 |
2006-01-05 |
Government Of The United States |
Skin-sctive adjuvants for transcutaneous immuization
|
|
US5980898A
(en)
|
1996-11-14 |
1999-11-09 |
The United States Of America As Represented By The U.S. Army Medical Research & Material Command |
Adjuvant for transcutaneous immunization
|
|
US20060002949A1
(en)
|
1996-11-14 |
2006-01-05 |
Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. |
Transcutaneous immunization without heterologous adjuvant
|
|
US6797276B1
(en)
|
1996-11-14 |
2004-09-28 |
The United States Of America As Represented By The Secretary Of The Army |
Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
|
|
US20040258703A1
(en)
*
|
1997-11-14 |
2004-12-23 |
The Government Of The Us, As Represented By The Secretary Of The Army |
Skin-active adjuvants for transcutaneous immunization
|
|
ES2205573T3
(es)
|
1997-11-28 |
2004-05-01 |
Sumitomo Pharmaceuticals Company, Limited |
Nuevo compuestos heterociclicos.
|
|
UA67760C2
(uk)
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
|
US6518280B2
(en)
|
1998-12-11 |
2003-02-11 |
3M Innovative Properties Company |
Imidazonaphthyridines
|
|
US6558951B1
(en)
*
|
1999-02-11 |
2003-05-06 |
3M Innovative Properties Company |
Maturation of dendritic cells with immune response modifying compounds
|
|
ATE529130T1
(de)
*
|
1999-04-08 |
2011-11-15 |
Intercell Usa Inc |
Trockenformulierung für transkutane immunisierung
|
|
US6573273B1
(en)
|
1999-06-10 |
2003-06-03 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
|
US6756382B2
(en)
*
|
1999-06-10 |
2004-06-29 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
|
US6331539B1
(en)
*
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
US6541485B1
(en)
|
1999-06-10 |
2003-04-01 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
|
US6376669B1
(en)
|
1999-11-05 |
2002-04-23 |
3M Innovative Properties Company |
Dye labeled imidazoquinoline compounds
|
|
US6916925B1
(en)
|
1999-11-05 |
2005-07-12 |
3M Innovative Properties Co. |
Dye labeled imidazoquinoline compounds
|
|
JP3436512B2
(ja)
*
|
1999-12-28 |
2003-08-11 |
株式会社デンソー |
アクセル装置
|
|
US6894060B2
(en)
*
|
2000-03-30 |
2005-05-17 |
3M Innovative Properties Company |
Method for the treatment of dermal lesions caused by envenomation
|
|
UA81099C2
(en)
*
|
2000-06-22 |
2007-12-10 |
|
System for treating a mucosal surface comprising an immune response modifier
|
|
JP2002145777A
(ja)
*
|
2000-11-06 |
2002-05-22 |
Sumitomo Pharmaceut Co Ltd |
アラキドン酸誘発皮膚疾患治療剤
|
|
US6525064B1
(en)
|
2000-12-08 |
2003-02-25 |
3M Innovative Properties Company |
Sulfonamido substituted imidazopyridines
|
|
US6664265B2
(en)
*
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
|
US6664260B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Heterocyclic ether substituted imidazoquinolines
|
|
US6660747B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
|
US6677347B2
(en)
*
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamido ether substituted imidazoquinolines
|
|
US6677348B2
(en)
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Aryl ether substituted imidazoquinolines
|
|
US6667312B2
(en)
*
|
2000-12-08 |
2003-12-23 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
|
CA2598144A1
(en)
*
|
2000-12-08 |
2006-08-31 |
3M Innovative Properties Company |
Compositions and methods for targeted delivery of immune response modifiers
|
|
US6664264B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
|
US6545017B1
(en)
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Urea substituted imidazopyridines
|
|
AU2002232498B2
(en)
*
|
2000-12-08 |
2006-05-04 |
3M Innovative Properties Company |
Screening method for identifying compounds that selectively induce interferon alpha
|
|
US6545016B1
(en)
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Amide substituted imidazopyridines
|
|
US6660735B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Urea substituted imidazoquinoline ethers
|
|
US20020107262A1
(en)
*
|
2000-12-08 |
2002-08-08 |
3M Innovative Properties Company |
Substituted imidazopyridines
|
|
EP1372708B1
(en)
*
|
2001-02-13 |
2008-06-18 |
GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE ARMY |
Vaccine for transcutaneous immunization against travellers' diarrhoea
|
|
US7226928B2
(en)
*
|
2001-06-15 |
2007-06-05 |
3M Innovative Properties Company |
Methods for the treatment of periodontal disease
|
|
JP2005501550A
(ja)
*
|
2001-08-30 |
2005-01-20 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫反応調整剤分子を用いた形質細胞様樹状細胞を成熟させる方法
|
|
JP2005519990A
(ja)
*
|
2001-10-12 |
2005-07-07 |
ユニバーシティ オブ アイオワ リサーチ ファウンデーション |
イミダゾキノリン化合物を用いて免疫応答を増強するための方法および産物
|
|
AU2002343728A1
(en)
*
|
2001-11-16 |
2003-06-10 |
3M Innovative Properties Company |
Methods and compositions related to irm compounds and toll-like receptor pathways
|
|
US7321033B2
(en)
|
2001-11-27 |
2008-01-22 |
Anadys Pharmaceuticals, Inc. |
3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
|
|
JP4447914B2
(ja)
*
|
2001-11-29 |
2010-04-07 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫応答調節物質を含む医薬品
|
|
CA2365732A1
(en)
*
|
2001-12-20 |
2003-06-20 |
Ibm Canada Limited-Ibm Canada Limitee |
Testing measurements
|
|
US6677349B1
(en)
*
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
HUE025145T2
(en)
*
|
2002-02-22 |
2016-01-28 |
Meda Ab |
A method for reducing and treating immunosuppression induced by ultraviolet B radiation
|
|
ES2734652T3
(es)
*
|
2002-04-04 |
2019-12-11 |
Zoetis Belgium S A |
Oligorribonucleótidos inmunoestimulantes que contienen G y U
|
|
CA2488801A1
(en)
*
|
2002-06-07 |
2003-12-18 |
3M Innovative Properties Company |
Ether substituted imidazopyridines
|
|
DK1545597T3
(da)
|
2002-08-15 |
2011-01-31 |
3M Innovative Properties Co |
Immunstimulerende sammensætninger og fremgangsmåde til stimulering af en immunrespons
|
|
EP1542688A4
(en)
*
|
2002-09-26 |
2010-06-02 |
3M Innovative Properties Co |
1H-imidazo dimers
|
|
AU2003287316A1
(en)
*
|
2002-12-11 |
2004-06-30 |
3M Innovative Properties Company |
Assays relating to toll-like receptor activity
|
|
AU2003287324A1
(en)
*
|
2002-12-11 |
2004-06-30 |
3M Innovative Properties Company |
Gene expression systems and recombinant cell lines
|
|
NZ540826A
(en)
|
2002-12-20 |
2008-07-31 |
3M Innovative Properties Co |
Aryl / hetaryl substituted imidazoquinolines
|
|
EP2572715A1
(en)
|
2002-12-30 |
2013-03-27 |
3M Innovative Properties Company |
Immunostimulatory Combinations
|
|
US20050267144A1
(en)
*
|
2003-01-06 |
2005-12-01 |
Eugene Mandrea |
Methods of stimulating immune response in virally infected individuals
|
|
US20060183767A1
(en)
*
|
2003-01-06 |
2006-08-17 |
Eugene Mandrea |
Methods of stimulating immune response in certain individuals
|
|
US7893083B2
(en)
*
|
2003-01-06 |
2011-02-22 |
Eugene Mandrea |
Method of treating genital herpes
|
|
WO2004071459A2
(en)
*
|
2003-02-13 |
2004-08-26 |
3M Innovative Properties Company |
Methods and compositions related to irm compounds and toll-like receptor 8
|
|
WO2004075865A2
(en)
*
|
2003-02-27 |
2004-09-10 |
3M Innovative Properties Company |
Selective modulation of tlr-mediated biological activity
|
|
EP1601365A4
(en)
|
2003-03-04 |
2009-11-11 |
3M Innovative Properties Co |
PROPHYLACTIC TREATMENT OF UV-INDUCED EPIDERMAL NEOPLASIA
|
|
US7163947B2
(en)
*
|
2003-03-07 |
2007-01-16 |
3M Innovative Properties Company |
1-Amino 1H-imidazoquinolines
|
|
EP1605943A4
(en)
*
|
2003-03-07 |
2008-01-16 |
3M Innovative Properties Co |
1-AMINO-1H-imidazoquinolines
|
|
US8426457B2
(en)
*
|
2003-03-13 |
2013-04-23 |
Medicis Pharmaceutical Corporation |
Methods of improving skin quality
|
|
US7179253B2
(en)
|
2003-03-13 |
2007-02-20 |
3M Innovative Properties Company |
Method of tattoo removal
|
|
CA2518082C
(en)
*
|
2003-03-13 |
2013-02-12 |
3M Innovative Properties Company |
Methods for diagnosing skin lesions
|
|
US20040192585A1
(en)
*
|
2003-03-25 |
2004-09-30 |
3M Innovative Properties Company |
Treatment for basal cell carcinoma
|
|
WO2004108072A2
(en)
*
|
2003-04-10 |
2004-12-16 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds using metal-containing particulate support materials
|
|
US20040265351A1
(en)
|
2003-04-10 |
2004-12-30 |
Miller Richard L. |
Methods and compositions for enhancing immune response
|
|
EP1617845A4
(en)
*
|
2003-04-28 |
2006-09-20 |
3M Innovative Properties Co |
COMPOSITIONS AND METHODS FOR INDUCING OPOID RECEPTORS
|
|
US20040242620A1
(en)
*
|
2003-05-20 |
2004-12-02 |
3M Innovative Properties Company |
Immune response modifier compounds for treatment of TH2 mediated and related diseases
|
|
WO2004110991A2
(en)
*
|
2003-06-06 |
2004-12-23 |
3M Innovative Properties Company |
PROCESS FOR IMIDAZO[4,5-c]PYRIDIN-4-AMINES
|
|
US20050032829A1
(en)
*
|
2003-06-06 |
2005-02-10 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
|
CA2533128A1
(en)
*
|
2003-07-31 |
2005-02-10 |
3M Innovative Properties Company |
Bioactive compositions comprising triazines
|
|
US8211906B1
(en)
|
2003-08-05 |
2012-07-03 |
Scherrer Lawrence C |
Method of inhibiting growth of neoplastic cells and inhibiting infection by administering an immune enhancer drug
|
|
WO2005016273A2
(en)
*
|
2003-08-05 |
2005-02-24 |
3M Innovative Properties Company |
Infection prophylaxis using immune response modifier compounds
|
|
AU2004266658A1
(en)
*
|
2003-08-12 |
2005-03-03 |
3M Innovative Properties Company |
Hydroxylamine substituted imidazo-containing compounds
|
|
US7799800B2
(en)
*
|
2003-08-14 |
2010-09-21 |
3M Innovative Properties Company |
Lipid-modified immune response modifiers
|
|
CA2536249A1
(en)
*
|
2003-08-25 |
2005-03-10 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds
|
|
US20050048072A1
(en)
*
|
2003-08-25 |
2005-03-03 |
3M Innovative Properties Company |
Immunostimulatory combinations and treatments
|
|
BRPI0413998A
(pt)
*
|
2003-08-27 |
2006-11-07 |
3M Innovative Properties Co |
imidazoquinolinas arilóxi e arilalquilenóxi substituìdas
|
|
US20060216333A1
(en)
*
|
2003-09-02 |
2006-09-28 |
Miller Richard L |
Methods related to the treatment of mucosal associated conditions
|
|
US20050054665A1
(en)
*
|
2003-09-05 |
2005-03-10 |
3M Innovative Properties Company |
Treatment for CD5+ B cell lymphoma
|
|
ES2342069T4
(es)
|
2003-09-05 |
2011-01-26 |
Anadys Pharmaceuticals, Inc. |
Ligandos de tlr7 para el tratamiento de la hepatitis c.
|
|
WO2005029037A2
(en)
*
|
2003-09-17 |
2005-03-31 |
3M Innovative Properties Company |
Selective modulation of tlr gene expression
|
|
US20090075980A1
(en)
*
|
2003-10-03 |
2009-03-19 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and Analogs Thereof
|
|
JP2007508305A
(ja)
|
2003-10-03 |
2007-04-05 |
スリーエム イノベイティブ プロパティズ カンパニー |
ピラゾロピリジンおよびその類似物
|
|
BRPI0414856A
(pt)
|
2003-10-03 |
2006-11-21 |
3M Innovative Properties Co |
imidazoquinolinas alcóxi-substituìdas
|
|
US7544697B2
(en)
*
|
2003-10-03 |
2009-06-09 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and analogs thereof
|
|
US20050096259A1
(en)
*
|
2003-10-31 |
2005-05-05 |
3M Innovative Properties Company |
Neutrophil activation by immune response modifier compounds
|
|
CA2545825A1
(en)
|
2003-11-14 |
2005-06-02 |
3M Innovative Properties Company |
Hydroxylamine substituted imidazo ring compounds
|
|
WO2005048933A2
(en)
*
|
2003-11-14 |
2005-06-02 |
3M Innovative Properties Company |
Oxime substituted imidazo ring compounds
|
|
CA2547020C
(en)
|
2003-11-25 |
2014-03-25 |
3M Innovative Properties Company |
1h-imidazo[4,5-c]pyridine-4-amine derivatives as immune response modifier
|
|
WO2005051324A2
(en)
*
|
2003-11-25 |
2005-06-09 |
3M Innovative Properties Company |
Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
US8940755B2
(en)
*
|
2003-12-02 |
2015-01-27 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
|
US20050226878A1
(en)
*
|
2003-12-02 |
2005-10-13 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
|
WO2005076783A2
(en)
*
|
2003-12-04 |
2005-08-25 |
3M Innovative Properties Company |
Sulfone substituted imidazo ring ethers
|
|
WO2005066170A1
(en)
*
|
2003-12-29 |
2005-07-21 |
3M Innovative Properties Company |
Arylalkenyl and arylalkynyl substituted imidazoquinolines
|
|
JP2007530450A
(ja)
*
|
2003-12-29 |
2007-11-01 |
スリーエム イノベイティブ プロパティズ カンパニー |
ピペラジン、[1,4]ジアゼパン、[1,4]ジアゾカン、および[1,5]ジアゾカン縮合イミダゾ環化合物
|
|
JP2007517055A
(ja)
*
|
2003-12-30 |
2007-06-28 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫応答の増強
|
|
AU2004312508A1
(en)
*
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
|
|
TW200533750A
(en)
*
|
2004-02-19 |
2005-10-16 |
Coley Pharm Group Inc |
Immunostimulatory viral RNA oligonucleotides
|
|
US20050201959A1
(en)
*
|
2004-03-11 |
2005-09-15 |
Vvii Newco 2003, Inc. |
Methods and compositions for altering skin coloration
|
|
EP1729768B1
(en)
*
|
2004-03-15 |
2018-01-10 |
Meda AB |
Immune response modifier formulations and methods
|
|
TW200612932A
(en)
*
|
2004-03-24 |
2006-05-01 |
3M Innovative Properties Co |
Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
|
AU2005244260B2
(en)
*
|
2004-04-09 |
2010-08-05 |
3M Innovative Properties Company |
Methods, compositions, and preparations for delivery of immune response modifiers
|
|
MXPA06012451A
(es)
*
|
2004-04-28 |
2007-01-31 |
3M Innovative Properties Co |
Composiciones y metodos para vacunacion por la mucosa.
|
|
US20050267145A1
(en)
*
|
2004-05-28 |
2005-12-01 |
Merrill Bryon A |
Treatment for lung cancer
|
|
US20080015184A1
(en)
*
|
2004-06-14 |
2008-01-17 |
3M Innovative Properties Company |
Urea Substituted Imidazopyridines, Imidazoquinolines, and Imidazonaphthyridines
|
|
WO2005123080A2
(en)
*
|
2004-06-15 |
2005-12-29 |
3M Innovative Properties Company |
Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
|
WO2006009826A1
(en)
*
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
US8541438B2
(en)
|
2004-06-18 |
2013-09-24 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
US7915281B2
(en)
*
|
2004-06-18 |
2011-03-29 |
3M Innovative Properties Company |
Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
|
|
WO2006009832A1
(en)
*
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Substituted imidazo ring systems and methods
|
|
CA2571360C
(en)
*
|
2004-06-18 |
2014-11-25 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines useful in inducing cytokine biosynthesis in animals
|
|
US7897609B2
(en)
*
|
2004-06-18 |
2011-03-01 |
3M Innovative Properties Company |
Aryl substituted imidazonaphthyridines
|
|
WO2006026470A2
(en)
*
|
2004-08-27 |
2006-03-09 |
3M Innovative Properties Company |
Hiv immunostimulatory compositions
|
|
US20090270443A1
(en)
*
|
2004-09-02 |
2009-10-29 |
Doris Stoermer |
1-amino imidazo-containing compounds and methods
|
|
EP1784180A4
(en)
|
2004-09-02 |
2009-07-22 |
3M Innovative Properties Co |
2-AMINO-1H-IMIDAZO RING SYSTEMS AND METHOD
|
|
ATE555786T1
(de)
*
|
2004-09-02 |
2012-05-15 |
3M Innovative Properties Co |
1-alkoxy 1h-imidazo-ringsysteme und verfahren
|
|
US20080193468A1
(en)
*
|
2004-09-08 |
2008-08-14 |
Children's Medical Center Corporation |
Method for Stimulating the Immune Response of Newborns
|
|
EP1804583A4
(en)
*
|
2004-10-08 |
2009-05-20 |
3M Innovative Properties Co |
ADJUVANT FOR DNA VACCINE
|
|
WO2007001448A2
(en)
*
|
2004-11-04 |
2007-01-04 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
US20110070575A1
(en)
*
|
2004-12-08 |
2011-03-24 |
Coley Pharmaceutical Group, Inc. |
Immunomodulatory Compositions, Combinations and Methods
|
|
US8080560B2
(en)
*
|
2004-12-17 |
2011-12-20 |
3M Innovative Properties Company |
Immune response modifier formulations containing oleic acid and methods
|
|
EP1824482B1
(en)
|
2004-12-17 |
2014-02-12 |
Anadys Pharmaceuticals, Inc. |
3, 5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO AND 3H-THIAZOLO [4,5-d]PYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF
|
|
US8436176B2
(en)
*
|
2004-12-30 |
2013-05-07 |
Medicis Pharmaceutical Corporation |
Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine
|
|
NZ556399A
(en)
*
|
2004-12-30 |
2009-03-31 |
Takeda Pharmaceutical |
1-(2-methylpropyl)-1H-imidazo[4,5-C][1,5]naphthyridin-4-amine ethanesulfonate and 1-(2-methylpropyl)-1H-imidazo[4,5-C][1,5]naphthyridin-4-amine methanesulfonate
|
|
AU2005322898B2
(en)
|
2004-12-30 |
2011-11-24 |
3M Innovative Properties Company |
Chiral fused (1,2)imidazo(4,5-c) ring compounds
|
|
US8034938B2
(en)
|
2004-12-30 |
2011-10-11 |
3M Innovative Properties Company |
Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
|
|
HUE025749T2
(en)
*
|
2004-12-30 |
2016-04-28 |
Meda Ab |
Use of Imiquimod to treat skin metastases from breast cancer
|
|
US9248127B2
(en)
*
|
2005-02-04 |
2016-02-02 |
3M Innovative Properties Company |
Aqueous gel formulations containing immune response modifiers
|
|
CA2602083A1
(en)
|
2005-02-09 |
2006-08-09 |
Coley Pharmaceutical Group, Inc. |
Oxime and hydroxylamine substituted thiazolo(4,5-c) ring compounds and methods
|
|
AU2006212765B2
(en)
*
|
2005-02-09 |
2012-02-02 |
3M Innovative Properties Company |
Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
CA2597446A1
(en)
*
|
2005-02-11 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Substituted imidazoquinolines and imidazonaphthyridines
|
|
US7968563B2
(en)
|
2005-02-11 |
2011-06-28 |
3M Innovative Properties Company |
Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
|
|
US8343993B2
(en)
|
2005-02-23 |
2013-01-01 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazonaphthyridines
|
|
US8158794B2
(en)
*
|
2005-02-23 |
2012-04-17 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazoquinoline compounds and methods
|
|
EP1850849A2
(en)
*
|
2005-02-23 |
2007-11-07 |
Coley Pharmaceutical Group, Inc. |
Method of preferentially inducing the biosynthesis of interferon
|
|
US8178677B2
(en)
*
|
2005-02-23 |
2012-05-15 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazoquinolines
|
|
BRPI0608011A2
(pt)
|
2005-03-14 |
2009-11-03 |
Graceway Pharmaceuticals Llc |
uso de uma formulação para o tratamento da queratose actìnica e uso de 2-metil-1-(2-metilpropil)-1h-imidazo[4,5-c][1,5] naftiridin-4-amina
|
|
WO2006107851A1
(en)
|
2005-04-01 |
2006-10-12 |
Coley Pharmaceutical Group, Inc. |
1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
|
|
CA2602683A1
(en)
|
2005-04-01 |
2006-10-12 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridine-1,4-diamines and analogs thereof
|
|
AU2006241166A1
(en)
|
2005-04-25 |
2006-11-02 |
3M Innovative Properties Company |
Immunostimulatory compositions
|
|
EP1931352B1
(en)
*
|
2005-08-22 |
2016-04-13 |
The Regents of The University of California |
Tlr agonists
|
|
BRPI0615788A2
(pt)
*
|
2005-09-09 |
2011-05-24 |
Coley Pharm Group Inc |
derivados de amida e carbamato de n-{2-[4-amino (etoximetil)-1h-imidazo [4,5-c] quinolin-1-il]-1,1-dimetiletil} metanossulfonamida, composição farmacêutica destes e seus usos
|
|
ZA200803029B
(en)
*
|
2005-09-09 |
2009-02-25 |
Coley Pharm Group Inc |
Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
|
|
US20070081962A1
(en)
*
|
2005-10-06 |
2007-04-12 |
Amit Munshi |
Novel delivery of immune response modifiers for removal of chronic tattoos
|
|
KR20080083270A
(ko)
*
|
2005-11-04 |
2008-09-17 |
콜레이 파마시티컬 그룹, 인코포레이티드 |
하이드록시 및 알콕시 치환된 1에이치 이미다조퀴놀린 및방법
|
|
AU2006318260B2
(en)
|
2005-11-21 |
2012-05-17 |
Anadys Pharmaceuticals, Inc. |
Process for the preparation of 5-amino-3H- thiazolo [4 , 5 -d] pyrimidin- 2 -one
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
EP1968582A4
(en)
*
|
2005-12-28 |
2011-02-16 |
3M Innovative Properties Co |
TREATMENT OF CUTTAN T CELL LYMPHOMA
|
|
US8951528B2
(en)
*
|
2006-02-22 |
2015-02-10 |
3M Innovative Properties Company |
Immune response modifier conjugates
|
|
US8329721B2
(en)
*
|
2006-03-15 |
2012-12-11 |
3M Innovative Properties Company |
Hydroxy and alkoxy substituted 1H-imidazonaphthyridines and methods
|
|
CA2648099C
(en)
*
|
2006-03-31 |
2012-05-29 |
The Brigham And Women's Hospital, Inc |
System for targeted delivery of therapeutic agents
|
|
US8367113B2
(en)
|
2006-05-15 |
2013-02-05 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
|
WO2007137117A2
(en)
*
|
2006-05-17 |
2007-11-29 |
Massachusetts Institute Of Technology |
Aptamer-directed drug delivery
|
|
CA2653941C
(en)
|
2006-05-31 |
2013-01-08 |
The Regents Of The University Of California |
Substituted amino purine derivatives and uses thereof
|
|
US7709448B2
(en)
|
2006-06-22 |
2010-05-04 |
Anadys Pharmaceuticals, Inc. |
Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione
|
|
US9381477B2
(en)
*
|
2006-06-23 |
2016-07-05 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
WO2008008432A2
(en)
*
|
2006-07-12 |
2008-01-17 |
Coley Pharmaceutical Group, Inc. |
Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
|
|
US7528115B2
(en)
|
2006-07-18 |
2009-05-05 |
Anadys Pharmaceuticals, Inc. |
Carbonate and carbamate prodrugs of thiazolo[4,5-d]pyrimidines
|
|
NO343857B1
(no)
*
|
2006-07-18 |
2019-06-24 |
Meda Ab |
Immunresponsmodifiserende skumformuleringer
|
|
US8124096B2
(en)
|
2006-07-31 |
2012-02-28 |
3M Innovative Properties Company |
Immune response modifier compositions and methods
|
|
WO2008019142A2
(en)
*
|
2006-08-04 |
2008-02-14 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
|
US8178539B2
(en)
*
|
2006-09-06 |
2012-05-15 |
3M Innovative Properties Company |
Substituted 3,4,6,7-tetrahydro-5H-1,2a,4a,8-tetraazacyclopenta[cd]phenalenes and methods
|
|
WO2008147456A2
(en)
*
|
2006-11-20 |
2008-12-04 |
Massachusetts Institute Of Technology |
Drug delivery systems using fc fragments
|
|
US20080149123A1
(en)
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
JP5425642B2
(ja)
|
2007-02-07 |
2014-02-26 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
合成tlrアゴニストの結合体およびそのための使用
|
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
|
JP2010523595A
(ja)
*
|
2007-04-04 |
2010-07-15 |
マサチューセッツ インスティテュート オブ テクノロジー |
ポリ(アミノ酸)ターゲッティング部分
|
|
US20110166092A1
(en)
|
2007-08-20 |
2011-07-07 |
Anadys Pharmaceuticals, Inc. |
Dosing methods for treating disease
|
|
CA2917512C
(en)
|
2007-10-12 |
2025-08-05 |
President And Fellows Of Harvard College |
VACCINE NANOTECHNOLOGY
|
|
WO2009099650A2
(en)
*
|
2008-02-07 |
2009-08-13 |
Carson Dennis A |
Treatment of bladder diseases with a tlr7 activator
|
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
US8591905B2
(en)
*
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
WO2010088924A1
(en)
|
2009-02-06 |
2010-08-12 |
Telormedix Sa |
Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
|
|
AU2010214112B2
(en)
|
2009-02-11 |
2015-04-09 |
The Regents Of The University Of California |
Toll-like receptor modulators and treatment of diseases
|
|
CN103800906B
(zh)
|
2009-03-25 |
2017-09-22 |
德克萨斯大学系统董事会 |
用于刺激哺乳动物对病原体的先天免疫抵抗力的组合物
|
|
US20110223201A1
(en)
*
|
2009-04-21 |
2011-09-15 |
Selecta Biosciences, Inc. |
Immunonanotherapeutics Providing a Th1-Biased Response
|
|
WO2010138193A2
(en)
|
2009-05-27 |
2010-12-02 |
Selecta Biosciences, Inc. |
Targeted synthetic nanocarriers with ph sensitive release of immunomodulatory agents
|
|
US20110033515A1
(en)
*
|
2009-08-04 |
2011-02-10 |
Rst Implanted Cell Technology |
Tissue contacting material
|
|
EP3311833A3
(en)
|
2009-08-26 |
2018-07-25 |
Selecta Biosciences, Inc. |
Compositions that induce t cell help
|
|
WO2011150264A2
(en)
|
2010-05-26 |
2011-12-01 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier combination vaccines
|
|
SI2606047T1
(sl)
|
2010-08-17 |
2017-04-26 |
3M Innovative Properties Company |
Lipidirani sestavki spojine, ki modificira imunski odgovor, formulacije in postopki
|
|
WO2012061717A1
(en)
|
2010-11-05 |
2012-05-10 |
Selecta Biosciences, Inc. |
Modified nicotinic compounds and related methods
|
|
EP2718292B1
(en)
|
2011-06-03 |
2018-03-14 |
3M Innovative Properties Company |
Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom
|
|
US9475804B2
(en)
|
2011-06-03 |
2016-10-25 |
3M Innovative Properties Company |
Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom
|
|
US20130023736A1
(en)
|
2011-07-21 |
2013-01-24 |
Stanley Dale Harpstead |
Systems for drug delivery and monitoring
|
|
CA2843274A1
(en)
|
2011-07-29 |
2013-02-07 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers that generate humoral and cytotoxic t lymphocyte (ctl) immune responses
|
|
NZ701324A
(en)
|
2012-05-04 |
2016-09-30 |
Pfizer |
Prostate-associated antigens and vaccine-based immunotherapy regimens
|
|
HUE051988T2
(hu)
|
2013-01-07 |
2021-04-28 |
Univ Pennsylvania |
Készítmények és eljárások bõr T-sejt lymphoma kezelésére
|
|
ES2762631T3
(es)
|
2013-03-14 |
2020-05-25 |
Harvard College |
Composiciones a base de nanopartículas
|
|
US9919029B2
(en)
|
2013-07-26 |
2018-03-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for the treatment of bacterial infections
|
|
EP3094342A4
(en)
|
2014-01-15 |
2017-12-27 |
Nikolai Khodarev |
Anti-tumor therapy
|
|
EP3556353A3
(en)
|
2014-02-25 |
2020-03-18 |
Merck Sharp & Dohme Corp. |
Lipid nanoparticle vaccine adjuvants and antigen delivery systems
|
|
CA2949237C
(en)
|
2014-05-16 |
2022-08-23 |
Amgen Inc. |
Assay for detecting th1 and th2 cell populations
|
|
WO2015200728A1
(en)
|
2014-06-25 |
2015-12-30 |
Selecta Biosciences, Inc. |
Methods and compositions for treatment with synthetic nanocarriers and immune checkpoint inhibitors
|
|
US9884866B2
(en)
|
2014-09-08 |
2018-02-06 |
Regents Of The University Of Minnesota |
Immunomodulators and immunomodulator conjugates
|
|
WO2016044839A2
(en)
|
2014-09-19 |
2016-03-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
|
EP3344623B1
(en)
|
2015-08-31 |
2021-02-17 |
3M Innovative Properties Company |
Imidazo[4,5-c]ring compounds containing substituted guanidine groups
|
|
WO2017040233A1
(en)
|
2015-08-31 |
2017-03-09 |
3M Innovative Properties Company |
GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS
|
|
US10526309B2
(en)
|
2015-10-02 |
2020-01-07 |
The University Of North Carolina At Chapel Hill |
Pan-TAM inhibitors and Mer/Axl dual inhibitors
|
|
US10730871B2
(en)
|
2016-01-28 |
2020-08-04 |
Regents Of The University Of Minnesota |
Immunomodulators and immunomodulator conjugates
|
|
US11697851B2
(en)
|
2016-05-24 |
2023-07-11 |
The Regents Of The University Of California |
Early ovarian cancer detection diagnostic test based on mRNA isoforms
|
|
EP3504215B1
(en)
|
2016-08-26 |
2022-04-06 |
3M Innovative Properties Company |
Fused [1,2]imidazo[4,5-c]ring compounds substituted with guanidino groups
|
|
BR112019004042A2
(pt)
|
2016-08-30 |
2019-05-28 |
Dana-Farber Cancer Institute, Inc. |
composições de liberação de fármaco e usos das mesmas
|
|
IL266562B2
(en)
|
2016-11-09 |
2024-11-01 |
Univ Texas |
Pharmaceutical compositions for adaptive immune modulation for use in a subject susceptible to allergen induced asthma
|
|
WO2018160552A1
(en)
|
2017-03-01 |
2018-09-07 |
3M Innovative Properties Company |
IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING GUANIDINE SUBSTITUTED BENZAMIDE GROUPS
|
|
PH12019502544B1
(en)
|
2017-05-19 |
2023-07-26 |
Superb Wisdom Ltd |
Derivatives of resiquimod
|
|
CN111511740B
(zh)
|
2017-12-20 |
2023-05-16 |
3M创新有限公司 |
用作免疫应答调节剂的带有支链连接基团的酰胺取代的咪唑并[4,5-c]喹啉化合物
|
|
CA3092545A1
(en)
|
2018-02-28 |
2019-09-06 |
3M Innovative Properties Company |
Substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group
|
|
CN112218864B
(zh)
|
2018-05-24 |
2023-09-08 |
3M创新有限公司 |
N-1支链环烷基取代的咪唑并[4,5-c]喹啉化合物、组合物和方法
|
|
US12060350B2
(en)
|
2018-07-02 |
2024-08-13 |
Regents Of The University Of Minnesota |
Therapeutic compounds and methods of use thereof
|
|
EP3887369B1
(en)
|
2018-11-26 |
2024-05-08 |
Solventum Intellectual Properties Company |
N-1 branched alkyl ether substituted imidazo[4,5-c]quinoline compounds, compositions, and methods
|
|
WO2020245706A1
(en)
|
2019-06-06 |
2020-12-10 |
3M Innovative Properties Company |
N-1 branched alkyl substituted imidazo[4,5-c]quinoline compounds, compositions, and methods
|
|
WO2020250089A1
(en)
|
2019-06-12 |
2020-12-17 |
3M Innovative Properties Company |
Phenethyl substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group
|
|
US12018082B2
(en)
*
|
2019-09-16 |
2024-06-25 |
The Regents Of The University Of California |
Methods and agents for treating infections
|
|
WO2021116420A1
(en)
|
2019-12-13 |
2021-06-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tlr7 and/or tlr8 agonists for the treatment of leptospirosis
|