JP2000516925A5 - - Google Patents

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Publication number
JP2000516925A5
JP2000516925A5 JP1998509180A JP50918098A JP2000516925A5 JP 2000516925 A5 JP2000516925 A5 JP 2000516925A5 JP 1998509180 A JP1998509180 A JP 1998509180A JP 50918098 A JP50918098 A JP 50918098A JP 2000516925 A5 JP2000516925 A5 JP 2000516925A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998509180A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000516925A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/014352 external-priority patent/WO1998004135A1/en
Publication of JP2000516925A publication Critical patent/JP2000516925A/ja
Publication of JP2000516925A5 publication Critical patent/JP2000516925A5/ja
Ceased legal-status Critical Current

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JP10509180A 1996-07-31 1997-07-30 カリウムチャンネル調節物質であるジフェニルヘテロ環化合物 Ceased JP2000516925A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2298396P 1996-07-31 1996-07-31
US60/022,983 1996-07-31
PCT/US1997/014352 WO1998004135A1 (en) 1996-07-31 1997-07-30 Diphenyl heterocycles as potassium channel modulators

Publications (2)

Publication Number Publication Date
JP2000516925A JP2000516925A (ja) 2000-12-19
JP2000516925A5 true JP2000516925A5 (enExample) 2005-02-10

Family

ID=21812455

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10509180A Ceased JP2000516925A (ja) 1996-07-31 1997-07-30 カリウムチャンネル調節物質であるジフェニルヘテロ環化合物

Country Status (18)

Country Link
US (3) US5869509A (enExample)
EP (1) EP0915856A4 (enExample)
JP (1) JP2000516925A (enExample)
KR (1) KR20000029735A (enExample)
CN (1) CN1116287C (enExample)
AR (1) AR008110A1 (enExample)
AU (1) AU711736B2 (enExample)
BR (1) BR9710793A (enExample)
CZ (1) CZ32199A3 (enExample)
HU (1) HUP0000063A3 (enExample)
IL (1) IL128308A (enExample)
NO (1) NO990428L (enExample)
NZ (1) NZ334403A (enExample)
PL (1) PL331385A1 (enExample)
RU (1) RU2175319C2 (enExample)
TW (1) TW467902B (enExample)
WO (1) WO1998004135A1 (enExample)
ZA (1) ZA976554B (enExample)

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US7022480B1 (en) 2001-10-11 2006-04-04 The Regents Of The University Of California Exons of the hSKCa3/KCNN3 gene
US7211561B2 (en) * 2001-10-12 2007-05-01 Cedars-Sinai Medical Center Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa)
US6613786B2 (en) 2001-11-02 2003-09-02 Bristol-Myers Squibb Company Thiophenyl triazol-3-one derivatives as smooth muscle relaxants
US7846671B2 (en) * 2002-01-28 2010-12-07 Bristol-Myers Squibb Company Methods of screening for agents that modulate the interaction of RGS and Gαq and urinary incontinence
TW200304820A (en) * 2002-03-25 2003-10-16 Avanir Pharmaceuticals Use of benzimidazole analogs in the treatment of cell proliferation
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
TWI276631B (en) * 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
TWI271402B (en) * 2002-10-15 2007-01-21 Tanabe Seiyaku Co Large conductance calcium-activated K channel opener
TW200505441A (en) 2003-03-24 2005-02-16 Hoffmann La Roche Non-nucleoside reverse transcriptase inhibitorsⅠ
CN1826111A (zh) * 2003-04-10 2006-08-30 阿文尼尔药品公司 用于治疗变应性和过增生性疾病的咪唑衍生物
GB0315111D0 (en) 2003-06-27 2003-07-30 Cancer Rec Tech Ltd Substituted 5-membered ring compounds and their use
US20050256179A1 (en) * 2003-08-08 2005-11-17 Sircar Jagadish C Selective pharmacologic inhibition of protein trafficking and related methods of treating human diseases
AU2005230867A1 (en) * 2004-03-26 2005-10-20 Amphora Discovery Corporation Certain triazole-based compounds, compositions, and uses thereof
CA2561718A1 (en) * 2004-04-13 2005-10-27 Icagen, Inc. Polycyclic pyridines as potassium ion channel modulators
CN1993332B (zh) 2004-07-27 2011-04-06 弗·哈夫曼-拉罗切有限公司 作为非核苷逆转录酶抑制剂的苄基三唑酮化合物
US8293778B2 (en) 2004-07-27 2012-10-23 Roche Palo Alto Llc Heterocyclic antiviral compounds
CA2583177A1 (en) 2004-10-13 2006-04-27 Ptc Therapeutics, Inc. Compounds for nonsense suppression, and methods for their use
ES2594874T3 (es) 2004-11-18 2016-12-23 Synta Pharmaceuticals Corp. Compuestos de triazol que modulan la actividad de HSP90
US20080188480A1 (en) * 2005-02-22 2008-08-07 Cedars-Sinai Medical Center Use of Sildenafil, Vardenafil and Other 5-Phosphodiesterase Inhibitors to Enhance Permeability of the Abnormal Blood-Brain Barrier
EP1934185A1 (en) 2005-08-12 2008-06-25 Synta Pharmaceuticals Corporation Pyrazole compounds that modulate hsp90 activity
CA2618724A1 (en) 2005-08-18 2007-02-22 Synta Pharmaceuticals Corp. Imidazole compounds that modulate hsp90 activity
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DE102006024024A1 (de) * 2006-05-23 2007-11-29 Bayer Healthcare Aktiengesellschaft Substituierte Arylimidazolone und -triazolone sowie ihre Verwendung
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AU2008233929A1 (en) 2007-03-29 2008-10-09 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
US20100137381A1 (en) * 2007-05-03 2010-06-03 Neurosearch A/S Acetamide derivatives as potassium channel modulators
EP2280948A1 (en) 2008-04-09 2011-02-09 Mitsubishi Tanabe Pharma Corporation Pyrimidine, pyridine and triazine derivatives as maxi-k channel openers.
US20090281089A1 (en) * 2008-04-11 2009-11-12 Genentech, Inc. Pyridyl inhibitors of hedgehog signalling
PE20091953A1 (es) * 2008-05-08 2010-01-09 Du Pont Azoles sustituidos como fungicidas
US9205086B2 (en) 2010-04-19 2015-12-08 Synta Pharmaceuticals Corp. Cancer therapy using a combination of a Hsp90 inhibitory compounds and a EGFR inhibitor
JP2014532712A (ja) 2011-11-02 2014-12-08 シンタ ファーマシューティカルズ コーポレーション トポイソメラーゼi阻害剤とhsp90阻害剤の組合せを使用する癌療法
AU2012332424A1 (en) 2011-11-02 2014-06-05 Synta Pharmaceuticals Corp. Combination therapy of Hsp90 inhibitors with platinum-containing agents
AU2012339679A1 (en) 2011-11-14 2014-06-12 Synta Pharmaceuticals Corp. Combination therapy of Hsp90 inhibitors with BRAF inhibitors
WO2013134562A1 (en) 2012-03-09 2013-09-12 Inception 2, Inc. Triazolone compounds and uses thereof
AU2013363398B2 (en) 2012-12-20 2017-06-01 Tempest Therapeutics, Inc. Triazolone compounds and uses thereof
MX2016002795A (es) 2013-09-06 2016-05-26 Inception 2 Inc Compuestos de triazolona y usos de los mismos.
US10681909B2 (en) 2014-08-29 2020-06-16 Fmc Corporation Herbicidal triazoles
CN104710379B (zh) * 2015-03-09 2017-01-18 华南理工大学 一种bms‑191011的合成方法
WO2020086149A1 (en) * 2018-10-26 2020-04-30 University Of South Florida Drug for treating tinnitus
AU2020363366A1 (en) * 2019-10-07 2022-04-21 D.E. Shaw Research, Llc Arylmethylene aromatic compounds as KV1.3 potassium shaker channel blockers
MX2022004127A (es) * 2019-10-07 2022-06-14 De Shaw Res Llc Compuestos heterociclicos de arilo como bloqueadores del canal de potasio tipo shaker kv1.3.
CN115504940A (zh) * 2021-06-23 2022-12-23 中国科学院上海药物研究所 一种酰胺类化合物、其制备方法和制药用途

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DE2940709A1 (de) * 1979-10-08 1981-04-16 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von in 1-stellung substituierten imidazolen
US5436252A (en) * 1986-12-19 1995-07-25 Merrell Dow Pharmaceuticals Inc. 5-aryl-3H-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders
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US5331002A (en) * 1990-04-19 1994-07-19 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3H-1,2,4-triazole-3-thiones useful as memory enhancers
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