ITMI911426A0 - Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici - Google Patents

Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici

Info

Publication number
ITMI911426A0
ITMI911426A0 IT91MI1426A ITMI911426A ITMI911426A0 IT MI911426 A0 ITMI911426 A0 IT MI911426A0 IT 91MI1426 A IT91MI1426 A IT 91MI1426A IT MI911426 A ITMI911426 A IT MI911426A IT MI911426 A0 ITMI911426 A0 IT MI911426A0
Authority
IT
Italy
Prior art keywords
benzothiazepines
cycling
preparation
phosphonic acids
phosphonic
Prior art date
Application number
IT91MI1426A
Other languages
English (en)
Inventor
Claudio Giordano
Maurizio Paiocchi
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of ITMI911426A0 publication Critical patent/ITMI911426A0/it
Priority to ITMI911426A priority Critical patent/IT1249318B/it
Priority to JP04157237A priority patent/JP3101841B2/ja
Priority to CH1419/92A priority patent/CH683100A5/it
Priority to GB9209636A priority patent/GB2255973B/en
Priority to CA002068231A priority patent/CA2068231C/en
Priority to BE9200430A priority patent/BE1005268A3/fr
Priority to US07/882,512 priority patent/US5223612A/en
Priority to FR9205861A priority patent/FR2676735B1/fr
Priority to AT0100292A priority patent/AT401176B/de
Priority to NL9200870A priority patent/NL194275C/nl
Priority to DE4217103A priority patent/DE4217103C2/de
Priority to SE9201609A priority patent/SE505880C2/sv
Priority to ES9201053A priority patent/ES2039166B1/es
Publication of ITMI911426A1 publication Critical patent/ITMI911426A1/it
Application granted granted Critical
Publication of IT1249318B publication Critical patent/IT1249318B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
ITMI911426A 1991-05-23 1991-05-23 Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici IT1249318B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
ITMI911426A IT1249318B (it) 1991-05-23 1991-05-23 Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici
JP04157237A JP3101841B2 (ja) 1991-05-23 1992-05-01 ホスホン酸での環化によるベンゾチアゼピンの製造法
CH1419/92A CH683100A5 (it) 1991-05-23 1992-05-04 Processo per la preparazione di benzotiazepina per ciclizzazione con acido fosfonico.
GB9209636A GB2255973B (en) 1991-05-23 1992-05-05 Preparation of a benzothiazepine derivative
CA002068231A CA2068231C (en) 1991-05-23 1992-05-08 Process for the preparation of benzothiazepines by cyclization with phosphonic acids
BE9200430A BE1005268A3 (fr) 1991-05-23 1992-05-11 Procede de preparation de benzothiazepines par cyclisation avec des acides phosphoniques.
US07/882,512 US5223612A (en) 1991-05-23 1992-05-13 Process for the preparation of benzothiazepines by cyclization with phosphonic acids
FR9205861A FR2676735B1 (fr) 1991-05-23 1992-05-14 Procede de preparation de benzothiazepines par cyclisation avec des acides phosphoniques.
AT0100292A AT401176B (de) 1991-05-23 1992-05-15 Verfahren zur herstellung eines benzothiazepins
NL9200870A NL194275C (nl) 1991-05-23 1992-05-18 Werkwijze voor de bereiding van benzothiazepinen door cyclisatie met fosfonzuren.
DE4217103A DE4217103C2 (de) 1991-05-23 1992-05-22 Verfahren zur Herstellung eines Benzothiazepins durch Cyclisierung mit Phosphonsäuren
SE9201609A SE505880C2 (sv) 1991-05-23 1992-05-22 Förfarande för framställning av bensotiazepiner genom cyklisering med fosfonsyror
ES9201053A ES2039166B1 (es) 1991-05-23 1992-05-22 Proceso para la preparacion de benzodiacepinas por ciclizacion con acidos fosfonicos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911426A IT1249318B (it) 1991-05-23 1991-05-23 Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici

Publications (3)

Publication Number Publication Date
ITMI911426A0 true ITMI911426A0 (it) 1991-05-23
ITMI911426A1 ITMI911426A1 (it) 1992-11-23
IT1249318B IT1249318B (it) 1995-02-22

Family

ID=11359974

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911426A IT1249318B (it) 1991-05-23 1991-05-23 Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici

Country Status (13)

Country Link
US (1) US5223612A (it)
JP (1) JP3101841B2 (it)
AT (1) AT401176B (it)
BE (1) BE1005268A3 (it)
CA (1) CA2068231C (it)
CH (1) CH683100A5 (it)
DE (1) DE4217103C2 (it)
ES (1) ES2039166B1 (it)
FR (1) FR2676735B1 (it)
GB (1) GB2255973B (it)
IT (1) IT1249318B (it)
NL (1) NL194275C (it)
SE (1) SE505880C2 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104275A (en) * 1992-01-10 1998-04-05 Tanabe Seiyaku Co Process for preparing optically active benzothiazepine compounds by asymmetric reduction
TW438787B (en) * 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester
IT1295376B1 (it) * 1997-10-22 1999-05-12 Zambon Spa Processo per il riciclo di un sottoprodotto della sintesi del diltiazem
HUP0101193A3 (en) 1997-12-19 2001-12-28 G D Searle & Co Chicago Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides
KR20160146787A (ko) * 2014-04-10 2016-12-21 아처 다니엘 미드랜드 캄파니 R-글루코시드, 당 알코올, 환원 당 알코올 및 환원 당 알코올의 퓨란 유도체의 합성

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
JPH0798813B2 (ja) * 1989-04-28 1995-10-25 田辺製薬株式会社 1,5―ベンゾチアゼピン誘導体の製法
DE69015682T2 (de) * 1989-04-28 1995-05-11 Tanabe Seiyaku Co Verfahren zur Herstellung von 1,5-Benzothiazepinderivaten.
US5128469A (en) * 1989-04-28 1992-07-07 Tanabe Seiyaku Co., Ltd. Process for preparing 1,5-benzothiazepine derivatives
AU628217B2 (en) * 1989-08-31 1992-09-10 Marion Merrell Dow Inc. Heterogeneous synthesis of azepinones from esters
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 1,5−ベンゾチアゼピン誘導体の製法

Also Published As

Publication number Publication date
GB2255973B (en) 1995-01-11
FR2676735A1 (fr) 1992-11-27
NL194275C (nl) 2001-11-05
CH683100A5 (it) 1994-01-14
DE4217103A1 (de) 1992-11-26
ES2039166B1 (es) 1994-04-01
GB2255973A (en) 1992-11-25
JP3101841B2 (ja) 2000-10-23
ES2039166A1 (es) 1993-08-16
ATA100292A (de) 1995-11-15
NL9200870A (nl) 1992-12-16
SE9201609D0 (sv) 1992-05-22
ITMI911426A1 (it) 1992-11-23
AT401176B (de) 1996-07-25
BE1005268A3 (fr) 1993-06-15
SE505880C2 (sv) 1997-10-20
GB9209636D0 (en) 1992-06-17
CA2068231C (en) 2002-10-29
FR2676735B1 (fr) 1994-01-28
IT1249318B (it) 1995-02-22
DE4217103C2 (de) 2000-08-10
NL194275B (nl) 2001-07-02
JPH05222016A (ja) 1993-08-31
CA2068231A1 (en) 1992-11-24
SE9201609L (sv) 1992-11-24
US5223612A (en) 1993-06-29

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970507