IT1282674B1 - Processo per la purificazione di agenti contrastografici opacizzanti - Google Patents

Processo per la purificazione di agenti contrastografici opacizzanti

Info

Publication number
IT1282674B1
IT1282674B1 IT96MI000339A ITMI960339A IT1282674B1 IT 1282674 B1 IT1282674 B1 IT 1282674B1 IT 96MI000339 A IT96MI000339 A IT 96MI000339A IT MI960339 A ITMI960339 A IT MI960339A IT 1282674 B1 IT1282674 B1 IT 1282674B1
Authority
IT
Italy
Prior art keywords
purification
matting
contrasting agents
agents
nanofiltration
Prior art date
Application number
IT96MI000339A
Other languages
English (en)
Inventor
Rodolfo Piva
Carlo Felice Viscardi
Massimo Gagna
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Publication of ITMI960339A0 publication Critical patent/ITMI960339A0/it
Priority to IT96MI000339A priority Critical patent/IT1282674B1/it
Priority to ES97904423T priority patent/ES2128287T3/es
Priority to CZ19982651A priority patent/CZ291744B6/cs
Priority to DE69700843T priority patent/DE69700843T2/de
Priority to CA002247029A priority patent/CA2247029C/en
Priority to EP97904423A priority patent/EP0902686B1/en
Priority to AT97904423T priority patent/ATE186844T1/de
Priority to CN97192492A priority patent/CN1084632C/zh
Priority to PCT/EP1997/000639 priority patent/WO1997030735A2/en
Priority to AU17243/97A priority patent/AU1724397A/en
Priority to KR10-1998-0706478A priority patent/KR100436529B1/ko
Priority to DE0902686T priority patent/DE902686T1/de
Priority to JP52975697A priority patent/JP4058110B2/ja
Priority to US08/804,118 priority patent/US5811581A/en
Priority to IN350MA1997 priority patent/IN190416B/en
Priority to ZA9701459A priority patent/ZA971459B/xx
Publication of ITMI960339A1 publication Critical patent/ITMI960339A1/it
Application granted granted Critical
Publication of IT1282674B1 publication Critical patent/IT1282674B1/it
Priority to NO19983834A priority patent/NO313228B1/no
Priority to HK99103251A priority patent/HK1018213A1/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/02—Reverse osmosis; Hyperfiltration ; Nanofiltration
    • B01D61/027—Nanofiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A20/00—Water conservation; Efficient water supply; Efficient water use
    • Y02A20/124—Water desalination
    • Y02A20/131—Reverse-osmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Steroid Compounds (AREA)
  • Drying Of Solid Materials (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
IT96MI000339A 1994-08-04 1996-02-23 Processo per la purificazione di agenti contrastografici opacizzanti IT1282674B1 (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT96MI000339A IT1282674B1 (it) 1996-02-23 1996-02-23 Processo per la purificazione di agenti contrastografici opacizzanti
PCT/EP1997/000639 WO1997030735A2 (en) 1996-02-23 1997-02-12 A process for the purification of opacifying contrast agents
KR10-1998-0706478A KR100436529B1 (ko) 1996-02-23 1997-02-12 불투명조영제의정제방법
DE69700843T DE69700843T2 (de) 1996-02-23 1997-02-12 Verfahren zur reinigung opazifierender kontrastmittel
CA002247029A CA2247029C (en) 1996-02-23 1997-02-12 A process for the purification of opacifying contrast agents
EP97904423A EP0902686B1 (en) 1996-02-23 1997-02-12 A process for the purification of opacifying contrast agents
AT97904423T ATE186844T1 (de) 1996-02-23 1997-02-12 Verfahren zur reinigung opazifierender kontrastmittel
CN97192492A CN1084632C (zh) 1996-02-23 1997-02-12 纯化遮光造影剂的方法
ES97904423T ES2128287T3 (es) 1996-02-23 1997-02-12 Procedimiento para la purificacion de agentes de contraste opacificadores.
AU17243/97A AU1724397A (en) 1996-02-23 1997-02-12 A process for the purification of opacifying contrast agents
CZ19982651A CZ291744B6 (cs) 1996-02-23 1997-02-12 Způsob čištění jodovaných neiontových rentgenových kontrastních látek
DE0902686T DE902686T1 (de) 1996-02-23 1997-02-12 Verfahren zur reinigung opazifierender kontrastmittel
JP52975697A JP4058110B2 (ja) 1996-02-23 1997-02-12 不透明造影剤の精製方法
US08/804,118 US5811581A (en) 1994-08-04 1997-02-20 Process for the purification of opacifying contrast agents
IN350MA1997 IN190416B (it) 1996-02-23 1997-02-20
ZA9701459A ZA971459B (en) 1996-02-23 1997-02-20 A process for the purification of opacifying contrast agents.
NO19983834A NO313228B1 (no) 1996-02-23 1998-08-20 En fremgangsmåte ved rensingen av opasifiserende kontrastmidler
HK99103251A HK1018213A1 (en) 1996-02-23 1999-07-28 A process for the purification of opacifying agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI000339A IT1282674B1 (it) 1996-02-23 1996-02-23 Processo per la purificazione di agenti contrastografici opacizzanti

Publications (3)

Publication Number Publication Date
ITMI960339A0 ITMI960339A0 (it) 1996-02-23
ITMI960339A1 ITMI960339A1 (it) 1997-08-23
IT1282674B1 true IT1282674B1 (it) 1998-03-31

Family

ID=11373370

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96MI000339A IT1282674B1 (it) 1994-08-04 1996-02-23 Processo per la purificazione di agenti contrastografici opacizzanti

Country Status (16)

Country Link
EP (1) EP0902686B1 (it)
JP (1) JP4058110B2 (it)
KR (1) KR100436529B1 (it)
CN (1) CN1084632C (it)
AT (1) ATE186844T1 (it)
AU (1) AU1724397A (it)
CA (1) CA2247029C (it)
CZ (1) CZ291744B6 (it)
DE (2) DE69700843T2 (it)
ES (1) ES2128287T3 (it)
HK (1) HK1018213A1 (it)
IN (1) IN190416B (it)
IT (1) IT1282674B1 (it)
NO (1) NO313228B1 (it)
WO (1) WO1997030735A2 (it)
ZA (1) ZA971459B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19736472C1 (de) * 1997-08-21 1999-04-22 Bernhard Dr Sixt Verfahren zum Herstellen von weitgehend nebenwirkungsfreien Kontrastmitteln
KR100574087B1 (ko) 2004-09-09 2006-04-27 주식회사태준제약 아이오디사놀의 제조방법
CN101790410A (zh) * 2007-08-27 2010-07-28 马林克罗特公司 通过纳米过滤和反相色谱法从水溶性化合物中去除二氧化硅
US8766002B2 (en) 2009-11-26 2014-07-01 Imax Diagnostic Imaging Holding Limited Preparation and purification of iodixanol
JP2014511344A (ja) * 2010-12-21 2014-05-15 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤を含む組成物の脱塩
GB201120138D0 (en) * 2011-11-22 2012-01-04 Glaxo Group Ltd Novel process
CA2890449C (en) * 2012-12-19 2020-12-29 Ge Healthcare As Purification of x-ray contrast agents
RU2657238C2 (ru) 2013-11-05 2018-06-09 Бракко Имэджинг Спа Способ получения йопамидола
CN104045580A (zh) * 2014-06-25 2014-09-17 上海华震科技有限公司 一种碘普罗胺脱色纯化工艺
CN111440084B (zh) * 2019-01-16 2023-01-06 苏州纳微科技股份有限公司 一种碘克沙醇的纯化方法
CN111609649B (zh) 2019-02-25 2022-01-18 Lg电子株式会社 入口冰箱及冰箱
CN113121377A (zh) * 2019-12-31 2021-07-16 江苏汉邦科技有限公司 碘克沙醇的纯化方法
CN111715877B (zh) * 2020-05-22 2022-06-03 深圳市华科创智技术有限公司 一种纳米银线的纯化方法
CN112724035A (zh) * 2021-03-01 2021-04-30 江苏汉邦科技有限公司 一种纯化制备碘佛醇水解物的方法
CN113061099A (zh) * 2021-03-27 2021-07-02 浙江司太立制药股份有限公司 一种高纯度碘造影剂单体的分离纯化方法
CN115403481A (zh) * 2022-04-13 2022-11-29 江苏宇田医药有限公司 一种通过离子交换树脂纯化碘海醇的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3110737A1 (de) * 1981-03-16 1982-10-14 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zum abtrennen und reinigen von wasserloeslichen, nicht-ionischen verbindungen
US5204405A (en) * 1988-11-09 1993-04-20 Nippon Petrochemicals Co., Ltd. Thermoplastic resin composition and method for preparing the same
US5204005A (en) * 1990-02-26 1993-04-20 Mallinckrodt, Inc. Reversed phase chromatographic process
IT1248741B (it) * 1991-02-26 1995-01-26 Bracco Spa Processo di concentrazione e di purificazione di composti organici
US5221485A (en) * 1991-12-03 1993-06-22 Mallinckrodt Medical, Inc. Purification of X-ray contrast agent, magnetic resonance imaging agent, or radiopharmaceuticals using reverse osmosis
US5160437A (en) * 1991-12-03 1992-11-03 Mallinckrodt Medical, Inc. Purification of crude Ioversol using reverse osmosis
IT1275427B (it) * 1995-05-16 1997-08-07 Bracco Spa Processo per la depirogenazione di soluzioni farmaceutiche iniettabili

Also Published As

Publication number Publication date
CN1211929A (zh) 1999-03-24
ITMI960339A1 (it) 1997-08-23
CZ265198A3 (cs) 1999-07-14
ITMI960339A0 (it) 1996-02-23
KR100436529B1 (ko) 2004-12-16
KR19990087090A (ko) 1999-12-15
JP4058110B2 (ja) 2008-03-05
CA2247029A1 (en) 1997-08-28
NO983834D0 (no) 1998-08-20
DE902686T1 (de) 1999-07-22
NO313228B1 (no) 2002-09-02
DE69700843T2 (de) 2000-03-16
ES2128287T1 (es) 1999-05-16
DE69700843D1 (de) 1999-12-30
ZA971459B (en) 1998-06-23
NO983834L (no) 1998-10-19
ES2128287T3 (es) 2000-02-16
AU1724397A (en) 1997-09-10
EP0902686A2 (en) 1999-03-24
WO1997030735A3 (en) 1997-10-23
EP0902686B1 (en) 1999-11-24
CA2247029C (en) 2007-07-31
JP2000504735A (ja) 2000-04-18
CZ291744B6 (cs) 2003-05-14
IN190416B (it) 2003-07-26
HK1018213A1 (en) 1999-12-17
CN1084632C (zh) 2002-05-15
WO1997030735A2 (en) 1997-08-28
ATE186844T1 (de) 1999-12-15

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Legal Events

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