IT1193395B - Complessi platino-diamminici e formulazioni farmaceutiche per il trattamento del cancro che li contengono - Google Patents

Complessi platino-diamminici e formulazioni farmaceutiche per il trattamento del cancro che li contengono

Info

Publication number
IT1193395B
IT1193395B IT27029/80A IT2702980A IT1193395B IT 1193395 B IT1193395 B IT 1193395B IT 27029/80 A IT27029/80 A IT 27029/80A IT 2702980 A IT2702980 A IT 2702980A IT 1193395 B IT1193395 B IT 1193395B
Authority
IT
Italy
Prior art keywords
platinum
treatment
pharmaceutical formulations
cancer containing
diamine complexes
Prior art date
Application number
IT27029/80A
Other languages
English (en)
Other versions
IT8027029A0 (it
Inventor
Eric Jan Bulten
Francois Verbeek
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of IT8027029A0 publication Critical patent/IT8027029A0/it
Application granted granted Critical
Publication of IT1193395B publication Critical patent/IT1193395B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT27029/80A 1980-01-03 1980-12-31 Complessi platino-diamminici e formulazioni farmaceutiche per il trattamento del cancro che li contengono IT1193395B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE8000032,A NL181434C (nl) 1980-01-03 1980-01-03 Platina(iv)-diamine-complexen, alsmede hun bereiding en toepassing.

Publications (2)

Publication Number Publication Date
IT8027029A0 IT8027029A0 (it) 1980-12-31
IT1193395B true IT1193395B (it) 1988-06-15

Family

ID=19834620

Family Applications (1)

Application Number Title Priority Date Filing Date
IT27029/80A IT1193395B (it) 1980-01-03 1980-12-31 Complessi platino-diamminici e formulazioni farmaceutiche per il trattamento del cancro che li contengono

Country Status (31)

Country Link
US (2) US4431666A (it)
JP (1) JPS56100796A (it)
AR (1) AR227903A1 (it)
AT (1) AT377242B (it)
AU (1) AU542600B2 (it)
BE (1) BE886929A (it)
CA (1) CA1154030A (it)
CH (1) CH650003A5 (it)
CS (1) CS239911B2 (it)
DD (1) DD156909A5 (it)
DE (1) DE3100017A1 (it)
DK (1) DK153468C (it)
ES (2) ES8205231A1 (it)
FI (1) FI72321C (it)
FR (1) FR2473046A1 (it)
GB (1) GB2066819B (it)
GR (1) GR72849B (it)
HU (1) HU184922B (it)
IE (1) IE50653B1 (it)
IL (1) IL61708A (it)
IT (1) IT1193395B (it)
LU (1) LU83046A1 (it)
NL (1) NL181434C (it)
NO (1) NO810004L (it)
NZ (1) NZ195926A (it)
PH (1) PH21998A (it)
PT (1) PT72298B (it)
SE (1) SE439921B (it)
SU (1) SU1083911A3 (it)
YU (1) YU41754B (it)
ZA (1) ZA8114B (it)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
US4599352A (en) * 1984-03-01 1986-07-08 The United States Of America As Represented By The Department Of Health And Human Services Antineoplastic platinum (IV) complexes and compositions
US4550187A (en) * 1984-04-12 1985-10-29 The Research Foundation Of State University Of New York Synthesis of platinum (IV) antineoplastic agents
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4658047A (en) * 1985-09-27 1987-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method of preparing 1,2-diaminocyclohexane tetrachloro platinum (IV) isomers
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
ATE86967T1 (de) * 1988-01-09 1993-04-15 Asta Medica Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe.
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
FI905018A0 (fi) * 1989-10-17 1990-10-12 Bristol Myers Squibb Co I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet.
US5196555A (en) * 1989-10-17 1993-03-23 Bristol-Myers Squibb Company Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity
US5130450A (en) * 1990-04-25 1992-07-14 Nippon Kayaku Kabushiki Kaisha Platinum complexes
GB9211291D0 (en) * 1992-05-28 1992-07-15 British Tech Group Antifungal compounds
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6264891B1 (en) * 1998-12-22 2001-07-24 Eos Biotechnology, Inc. Apparatus and method for concurrent chemical synthesis
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CN105198933B (zh) * 2014-06-20 2018-08-14 贵州益佰制药股份有限公司 一种洛铂晶体、制备方法及药物应用
AU2016284156B2 (en) 2015-06-24 2020-01-30 Nippon Kayaku Kabushiki Kaisha Novel platinum (IV) complex
RU2715048C2 (ru) 2015-09-14 2020-02-25 Ниппон Каяку Кабусики Каися Полимерный конъюгат гексакоординированного комплекса платины
CN105713046B (zh) * 2016-02-01 2018-10-26 复旦大学 一种铂类抗肿瘤前体药物，其纳米水凝胶药物及其制备方法
CN106946946A (zh) * 2017-03-29 2017-07-14 昆明贵研药业有限公司 一种铂类抗肿瘤药物米铂氧化物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (it) * 1972-06-08 1978-09-29 Research Corp
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
SE7810798L (sv) * 1977-10-19 1979-04-20 Johnson Matthey Co Ltd Kompositioner, innehallande platina
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
SE7903360L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
SE7903359L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体

Also Published As

Publication number Publication date
NL181434B (nl) 1987-03-16
CS239911B2 (en) 1986-01-16
DE3100017A1 (de) 1981-11-19
PH21998A (en) 1988-05-02
DK153468B (da) 1988-07-18
CH650003A5 (de) 1985-06-28
FI810002L (fi) 1981-07-04
DK1681A (da) 1981-07-04
NL181434C (nl) 1987-08-17
ES507474A0 (es) 1982-09-01
CA1154030A (en) 1983-09-20
IE50653B1 (en) 1986-06-11
ES498240A0 (es) 1982-06-01
FI72321C (fi) 1987-05-11
NZ195926A (en) 1983-04-12
YU336380A (en) 1983-10-31
IT8027029A0 (it) 1980-12-31
ES8205231A1 (es) 1982-06-01
DD156909A5 (de) 1982-09-29
GR72849B (it) 1983-12-07
AT377242B (de) 1985-02-25
AU6594981A (en) 1981-07-09
JPS56100796A (en) 1981-08-12
YU41754B (en) 1987-12-31
HU184922B (en) 1984-11-28
IL61708A0 (en) 1981-01-30
US4431666A (en) 1984-02-14
GB2066819A (en) 1981-07-15
FR2473046B1 (it) 1985-03-01
NO810004L (no) 1981-07-06
DK153468C (da) 1988-12-12
ES8207119A1 (es) 1982-09-01
LU83046A1 (de) 1981-03-27
ZA8114B (en) 1982-01-27
FI72321B (fi) 1987-01-30
SU1083911A3 (ru) 1984-03-30
IL61708A (en) 1984-05-31
FR2473046A1 (fr) 1981-07-10
GB2066819B (en) 1984-01-18
PT72298A (en) 1981-01-01
JPH0428716B2 (it) 1992-05-15
BE886929A (nl) 1981-06-30
SE439921B (sv) 1985-07-08
SE8100006L (sv) 1981-07-04
US4482569A (en) 1984-11-13
PT72298B (en) 1981-11-10
IE802744L (en) 1981-07-03
ATA381A (de) 1984-07-15
NL8000032A (nl) 1981-08-03
AU542600B2 (en) 1985-02-28
AR227903A1 (es) 1982-12-30

Similar Documents

Publication Publication Date Title
IT1193395B (it) Complessi platino-diamminici e formulazioni farmaceutiche per il trattamento del cancro che li contengono
DK464383A (da) Medikamentadministreringsapparat
GB2024823B (en) Platinum-diamine complexes for use in the treatment of cancer
IT1114950B (it) Composizioni per il trattamento e la terapia di acne
PT73686A (pt) Pharmaceutical formulation
BR7803026A (pt) Penso medicinal
BE896027A (fr) Nouvelles glycoproteines, procedes de production et agents therapeutiques pour le traitement de tumeurs en contenant
GB2093845B (en) Platinum-diamine complexes useful for the treatment of cancer
JPS55147223A (en) Pharmaceutical medicine
BR8107984A (pt) Monitor medico
FI811484L (fi) Medels tryckmedium fungerande betthaollare
GB2081094B (en) The use of dithiocarbamic compounds in cancer therapy
IT1170728B (it) Dispositivo per la somministrazione di sostanze medicamentose
GB2098478B (en) Propioibacteria preparations for use in the treatment of tumours
BE828620A (fr) Appareil d'irradiation electromedical pour la lutte contre le cancer
BE852095A (fr) Composition pharmaceutique pour le traitement de la leucemie et de tumeurs
IT1144837B (it) Posto di trattamento dentistico
IT8319024A0 (it) Composizione medicinale per il trattamento di certe neurovirosi.
JPS5524172A (en) Benzimidazole*its manufacture and pharmaceutic medicine containing it
ZA816321B (en) Ammoniomethyl compounds,processes for their manufacture,pharmaceutical preparations that contain these compounds,and the use of these compounds
MC1371A1 (fr) Preparations pharmaceutiques
ZA763081B (en) Pharmaceutical preparations for the treatment of hyperuricacidemia
JPS56100746A (en) Novel benzeneamines*anticoccidial and fungicidal medicine and treatment
IT1192960B (it) Preparato per il trattamento del l acne
IT8168327A0 (it) Armadio con cassetti particolarmente per medicinali o attrezzature per trattamento dentistico