ZA8114B - Platnum (iv)-diamine-complexes,a process for the preparation thereof ,a process for the preparation of a medicine using such a platinum (iv) -diamine-complex for the treamentof cancer as well as the shaped medicine thus obtained - Google Patents

Platnum (iv)-diamine-complexes,a process for the preparation thereof ,a process for the preparation of a medicine using such a platinum (iv) -diamine-complex for the treamentof cancer as well as the shaped medicine thus obtained

Info

Publication number
ZA8114B
ZA8114B ZA00810014A ZA8114A ZA8114B ZA 8114 B ZA8114 B ZA 8114B ZA 00810014 A ZA00810014 A ZA 00810014A ZA 8114 A ZA8114 A ZA 8114A ZA 8114 B ZA8114 B ZA 8114B
Authority
ZA
South Africa
Prior art keywords
diamine
preparation
medicine
treamentof
platnum
Prior art date
Application number
ZA00810014A
Other languages
English (en)
Inventor
F Verbeek
E Bulten
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of ZA8114B publication Critical patent/ZA8114B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00810014A 1980-01-03 1981-01-02 Platnum (iv)-diamine-complexes,a process for the preparation thereof ,a process for the preparation of a medicine using such a platinum (iv) -diamine-complex for the treamentof cancer as well as the shaped medicine thus obtained ZA8114B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE8000032,A NL181434C (nl) 1980-01-03 1980-01-03 Platina(iv)-diamine-complexen, alsmede hun bereiding en toepassing.

Publications (1)

Publication Number Publication Date
ZA8114B true ZA8114B (en) 1982-01-27

Family

ID=19834620

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00810014A ZA8114B (en) 1980-01-03 1981-01-02 Platnum (iv)-diamine-complexes,a process for the preparation thereof ,a process for the preparation of a medicine using such a platinum (iv) -diamine-complex for the treamentof cancer as well as the shaped medicine thus obtained

Country Status (31)

Country Link
US (2) US4431666A (it)
JP (1) JPS56100796A (it)
AR (1) AR227903A1 (it)
AT (1) AT377242B (it)
AU (1) AU542600B2 (it)
BE (1) BE886929A (it)
CA (1) CA1154030A (it)
CH (1) CH650003A5 (it)
CS (1) CS239911B2 (it)
DD (1) DD156909A5 (it)
DE (1) DE3100017A1 (it)
DK (1) DK153468C (it)
ES (2) ES8205231A1 (it)
FI (1) FI72321C (it)
FR (1) FR2473046A1 (it)
GB (1) GB2066819B (it)
GR (1) GR72849B (it)
HU (1) HU184922B (it)
IE (1) IE50653B1 (it)
IL (1) IL61708A (it)
IT (1) IT1193395B (it)
LU (1) LU83046A1 (it)
NL (1) NL181434C (it)
NO (1) NO810004L (it)
NZ (1) NZ195926A (it)
PH (1) PH21998A (it)
PT (1) PT72298B (it)
SE (1) SE439921B (it)
SU (1) SU1083911A3 (it)
YU (1) YU41754B (it)
ZA (1) ZA8114B (it)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
US4599352A (en) * 1984-03-01 1986-07-08 The United States Of America As Represented By The Department Of Health And Human Services Antineoplastic platinum (IV) complexes and compositions
US4550187A (en) * 1984-04-12 1985-10-29 The Research Foundation Of State University Of New York Synthesis of platinum (IV) antineoplastic agents
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4658047A (en) * 1985-09-27 1987-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method of preparing 1,2-diaminocyclohexane tetrachloro platinum (IV) isomers
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
ATE86967T1 (de) * 1988-01-09 1993-04-15 Asta Medica Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe.
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
FI905018A0 (fi) * 1989-10-17 1990-10-12 Bristol Myers Squibb Co I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet.
US5196555A (en) * 1989-10-17 1993-03-23 Bristol-Myers Squibb Company Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity
US5130450A (en) * 1990-04-25 1992-07-14 Nippon Kayaku Kabushiki Kaisha Platinum complexes
GB9211291D0 (en) * 1992-05-28 1992-07-15 British Tech Group Antifungal compounds
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6264891B1 (en) * 1998-12-22 2001-07-24 Eos Biotechnology, Inc. Apparatus and method for concurrent chemical synthesis
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CN105198933B (zh) * 2014-06-20 2018-08-14 贵州益佰制药股份有限公司 一种洛铂晶体、制备方法及药物应用
AU2016284156B2 (en) 2015-06-24 2020-01-30 Nippon Kayaku Kabushiki Kaisha Novel platinum (IV) complex
RU2715048C2 (ru) 2015-09-14 2020-02-25 Ниппон Каяку Кабусики Каися Полимерный конъюгат гексакоординированного комплекса платины
CN105713046B (zh) * 2016-02-01 2018-10-26 复旦大学 一种铂类抗肿瘤前体药物，其纳米水凝胶药物及其制备方法
CN106946946A (zh) * 2017-03-29 2017-07-14 昆明贵研药业有限公司 一种铂类抗肿瘤药物米铂氧化物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (it) * 1972-06-08 1978-09-29 Research Corp
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
SE7810798L (sv) * 1977-10-19 1979-04-20 Johnson Matthey Co Ltd Kompositioner, innehallande platina
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
SE7903360L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
SE7903359L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体

Also Published As

Publication number Publication date
NL181434B (nl) 1987-03-16
CS239911B2 (en) 1986-01-16
DE3100017A1 (de) 1981-11-19
PH21998A (en) 1988-05-02
DK153468B (da) 1988-07-18
CH650003A5 (de) 1985-06-28
FI810002L (fi) 1981-07-04
DK1681A (da) 1981-07-04
NL181434C (nl) 1987-08-17
ES507474A0 (es) 1982-09-01
CA1154030A (en) 1983-09-20
IE50653B1 (en) 1986-06-11
ES498240A0 (es) 1982-06-01
FI72321C (fi) 1987-05-11
NZ195926A (en) 1983-04-12
YU336380A (en) 1983-10-31
IT8027029A0 (it) 1980-12-31
ES8205231A1 (es) 1982-06-01
DD156909A5 (de) 1982-09-29
GR72849B (it) 1983-12-07
AT377242B (de) 1985-02-25
AU6594981A (en) 1981-07-09
JPS56100796A (en) 1981-08-12
YU41754B (en) 1987-12-31
HU184922B (en) 1984-11-28
IL61708A0 (en) 1981-01-30
US4431666A (en) 1984-02-14
GB2066819A (en) 1981-07-15
FR2473046B1 (it) 1985-03-01
NO810004L (no) 1981-07-06
DK153468C (da) 1988-12-12
ES8207119A1 (es) 1982-09-01
LU83046A1 (de) 1981-03-27
FI72321B (fi) 1987-01-30
SU1083911A3 (ru) 1984-03-30
IT1193395B (it) 1988-06-15
IL61708A (en) 1984-05-31
FR2473046A1 (fr) 1981-07-10
GB2066819B (en) 1984-01-18
PT72298A (en) 1981-01-01
JPH0428716B2 (it) 1992-05-15
BE886929A (nl) 1981-06-30
SE439921B (sv) 1985-07-08
SE8100006L (sv) 1981-07-04
US4482569A (en) 1984-11-13
PT72298B (en) 1981-11-10
IE802744L (en) 1981-07-03
ATA381A (de) 1984-07-15
NL8000032A (nl) 1981-08-03
AU542600B2 (en) 1985-02-28
AR227903A1 (es) 1982-12-30

Similar Documents

Publication Publication Date Title
ZA8114B (en) Platnum (iv)-diamine-complexes,a process for the preparation thereof ,a process for the preparation of a medicine using such a platinum (iv) -diamine-complex for the treamentof cancer as well as the shaped medicine thus obtained
MY8600400A (en) Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the trement of cancer,as well as a medicine thus formed
MY8700363A (en) 7-amino-1-gyclopropyl-4-oxo-1, 4-dihydronaphthyridine-3-carboxylic acids, process for their preparation and medicaments containing these compounds
HUT37410A (en) Process for the production of benzothiazole- and benzothiophene-derivatives, as well as of therapeutic preparations containing them as agent
AR242187A1 (es) Procedimiento para la preparacion de 1-hidroxi-2-piridonas, obtencion de medicamentos que las contienen, e intermediarios utiles en dicho procedimiento.
PL232259A1 (en) Process for preparing pharmaceutical preparation
EP0044453A3 (en) New benzisoselenazolones, process for producing the same and pharmaceutical preparations containing the same
IL62960A0 (en) Imidazoazole compounds,their production and pharmaceutical compositions containing them
DE3172006D1 (en) Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof
PH23776A (en) Thienopyridinone derivatives,process for their preparation
PT75472A (en) Process for preparing novel imidazoquinazoline derivativesand pharmaceutical compositions containing the same
DE3166656D1 (en) 1-phenyl-2-cyclohexene-1-alkylamine derivatives, process for their preparation and medicines containing them
IL62842A0 (en) Process for the preparation of n-di-n-propyl-2,6-dinitro-4-trifluoro-methylaniline
DE3263829D1 (en) Imidazodiazepines, process and intermediates for their preparation and medicaments containing them
DE3161047D1 (en) Process for the preparation of hexafluoraceton, and the use of the solution obtained by this process
IL62988A0 (en) Germanium compounds,a process for the preparation thereof,a process for the preparation of a medicine using such a germanium compound for the treatment of cancer,as well as the shaped medicine thus formed and obtained
ZA815684B (en) Novel diaryl-imidazole compounds,processes for their manufacture,pharmaceutical preparations containing these compounds,and their use
DE3165498D1 (en) Process for the preparation of erythromycylamine 11,12-carbonate
DE2860614D1 (en) N-benzylpyrimidinyl-amidines, process for their preparation and medicines containing them
IL62987A0 (en) Tin compounds,a process for the preparation thereof,a process for the preparation of a medicine using such a tin compound for the treatment of cancer,as well as the shaped medicine thus formed and obtained
ZA815621B (en) Novel polyazaheterocyclic compounds,process for their manufacture and pharmaceutical preparations containing them
DE3166751D1 (en) Pentapeptides of the encephaline type, process for their preparation and medicaments containing these
EP0042092A3 (en) 1,4-dihydropyridine-4-carboxamides, process for preparing them, their use as medicines and preparation thereof
DE2967433D1 (en) 3-amino-cardenolides, process for their preparation and medicines containing them
ZA813621B (en) Tin compounds,a process for the preparation thereof,a process for the preparation of a medicine using such a tin compound for the treatment of cancer,as well as the shaped medicine thus formed and obtained