SE8100006L - Platina (iv) diamin-komplex, sett att framstella dessa komplex och ett lekemedel utnyttjande ett dylikt komplex for behandling av cancer samt det pa sa sett erhallna lekemedlet - Google Patents

Platina (iv) diamin-komplex, sett att framstella dessa komplex och ett lekemedel utnyttjande ett dylikt komplex for behandling av cancer samt det pa sa sett erhallna lekemedlet

Info

Publication number
SE8100006L
SE8100006L SE8100006A SE8100006A SE8100006L SE 8100006 L SE8100006 L SE 8100006L SE 8100006 A SE8100006 A SE 8100006A SE 8100006 A SE8100006 A SE 8100006A SE 8100006 L SE8100006 L SE 8100006L
Authority
SE
Sweden
Prior art keywords
complex
medicine
diamine
platina
prepare
Prior art date
Application number
SE8100006A
Other languages
Unknown language ( )
English (en)
Other versions
SE439921B (sv
Inventor
E J Bulten
F Verbeek
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of SE8100006L publication Critical patent/SE8100006L/sv
Publication of SE439921B publication Critical patent/SE439921B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8100006A 1980-01-03 1981-01-02 Nya platina(iv)diamin-komplex, sett att framstella dessa komplex och ett lekemedel till anvendning for behandling av cancer SE439921B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE8000032,A NL181434C (nl) 1980-01-03 1980-01-03 Platina(iv)-diamine-complexen, alsmede hun bereiding en toepassing.

Publications (2)

Publication Number Publication Date
SE8100006L true SE8100006L (sv) 1981-07-04
SE439921B SE439921B (sv) 1985-07-08

Family

ID=19834620

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8100006A SE439921B (sv) 1980-01-03 1981-01-02 Nya platina(iv)diamin-komplex, sett att framstella dessa komplex och ett lekemedel till anvendning for behandling av cancer

Country Status (31)

Country Link
US (2) US4431666A (sv)
JP (1) JPS56100796A (sv)
AR (1) AR227903A1 (sv)
AT (1) AT377242B (sv)
AU (1) AU542600B2 (sv)
BE (1) BE886929A (sv)
CA (1) CA1154030A (sv)
CH (1) CH650003A5 (sv)
CS (1) CS239911B2 (sv)
DD (1) DD156909A5 (sv)
DE (1) DE3100017A1 (sv)
DK (1) DK153468C (sv)
ES (2) ES498240A0 (sv)
FI (1) FI72321C (sv)
FR (1) FR2473046A1 (sv)
GB (1) GB2066819B (sv)
GR (1) GR72849B (sv)
HU (1) HU184922B (sv)
IE (1) IE50653B1 (sv)
IL (1) IL61708A (sv)
IT (1) IT1193395B (sv)
LU (1) LU83046A1 (sv)
NL (1) NL181434C (sv)
NO (1) NO810004L (sv)
NZ (1) NZ195926A (sv)
PH (1) PH21998A (sv)
PT (1) PT72298B (sv)
SE (1) SE439921B (sv)
SU (1) SU1083911A3 (sv)
YU (1) YU41754B (sv)
ZA (1) ZA8114B (sv)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
US4599352A (en) * 1984-03-01 1986-07-08 The United States Of America As Represented By The Department Of Health And Human Services Antineoplastic platinum (IV) complexes and compositions
US4550187A (en) * 1984-04-12 1985-10-29 The Research Foundation Of State University Of New York Synthesis of platinum (IV) antineoplastic agents
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4658047A (en) * 1985-09-27 1987-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method of preparing 1,2-diaminocyclohexane tetrachloro platinum (IV) isomers
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
DE3843571A1 (de) * 1988-01-09 1989-07-20 Asta Pharma Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
US5196555A (en) * 1989-10-17 1993-03-23 Bristol-Myers Squibb Company Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity
FI905018A0 (fi) * 1989-10-17 1990-10-12 Bristol Myers Squibb Co I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet.
US5130450A (en) * 1990-04-25 1992-07-14 Nippon Kayaku Kabushiki Kaisha Platinum complexes
GB9211291D0 (en) * 1992-05-28 1992-07-15 British Tech Group Antifungal compounds
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6264891B1 (en) * 1998-12-22 2001-07-24 Eos Biotechnology, Inc. Apparatus and method for concurrent chemical synthesis
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CN105198933B (zh) * 2014-06-20 2018-08-14 贵州益佰制药股份有限公司 一种洛铂晶体、制备方法及药物应用
CA2990369A1 (en) 2015-06-24 2016-12-29 Nippon Kayaku Kabushiki Kaisha Novel platinum (iv) complex
AU2016324370B2 (en) 2015-09-14 2021-02-25 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of hexa-coordinated platinum complex
CN105713046B (zh) * 2016-02-01 2018-10-26 复旦大学 一种铂类抗肿瘤前体药物,其纳米水凝胶药物及其制备方法
CN106946946A (zh) * 2017-03-29 2017-07-14 昆明贵研药业有限公司 一种铂类抗肿瘤药物米铂氧化物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588505A5 (sv) * 1972-06-08 1977-06-15 Research Corp
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
SE7810798L (sv) * 1977-10-19 1979-04-20 Johnson Matthey Co Ltd Kompositioner, innehallande platina
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
SE7903360L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
SE7903359L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体

Also Published As

Publication number Publication date
ES8207119A1 (es) 1982-09-01
DK153468C (da) 1988-12-12
GB2066819B (en) 1984-01-18
ES8205231A1 (es) 1982-06-01
SE439921B (sv) 1985-07-08
SU1083911A3 (ru) 1984-03-30
IT1193395B (it) 1988-06-15
NO810004L (no) 1981-07-06
US4482569A (en) 1984-11-13
ES498240A0 (es) 1982-06-01
AR227903A1 (es) 1982-12-30
HU184922B (en) 1984-11-28
IL61708A0 (en) 1981-01-30
FI810002L (fi) 1981-07-04
GB2066819A (en) 1981-07-15
FI72321B (fi) 1987-01-30
AT377242B (de) 1985-02-25
DD156909A5 (de) 1982-09-29
DE3100017A1 (de) 1981-11-19
ES507474A0 (es) 1982-09-01
NZ195926A (en) 1983-04-12
ZA8114B (en) 1982-01-27
PH21998A (en) 1988-05-02
YU41754B (en) 1987-12-31
FR2473046A1 (fr) 1981-07-10
IL61708A (en) 1984-05-31
AU542600B2 (en) 1985-02-28
LU83046A1 (de) 1981-03-27
BE886929A (nl) 1981-06-30
YU336380A (en) 1983-10-31
CS239911B2 (en) 1986-01-16
FI72321C (sv) 1987-05-11
IT8027029A0 (it) 1980-12-31
NL181434C (nl) 1987-08-17
PT72298A (en) 1981-01-01
JPS56100796A (en) 1981-08-12
GR72849B (sv) 1983-12-07
JPH0428716B2 (sv) 1992-05-15
ATA381A (de) 1984-07-15
DK1681A (da) 1981-07-04
PT72298B (en) 1981-11-10
IE50653B1 (en) 1986-06-11
AU6594981A (en) 1981-07-09
CH650003A5 (de) 1985-06-28
FR2473046B1 (sv) 1985-03-01
IE802744L (en) 1981-07-03
NL181434B (nl) 1987-03-16
DK153468B (da) 1988-07-18
CA1154030A (en) 1983-09-20
US4431666A (en) 1984-02-14
NL8000032A (nl) 1981-08-03

Similar Documents

Publication Publication Date Title
SE8100006L (sv) Platina (iv) diamin-komplex, sett att framstella dessa komplex och ett lekemedel utnyttjande ett dylikt komplex for behandling av cancer samt det pa sa sett erhallna lekemedlet
HK9986A (en) Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer,as well as a medicine thus formed
DE3689363D1 (de) Pharmazeutische Zusammensetzungen zur Behandlung der Metastasen von Krebstumoren.
ATE399560T1 (de) Pharmazeutische zusammensetzungen enthaltend arsentrioxid zur behandlung von nicht-hodgkihn- lymphome
DE69127175D1 (de) Antisens-Oligonukleotide zur Behandlung von Krebs
DE3885317D1 (de) Makromolekulare Platin-Antitumorverbindungen.
PT76394A (fr) Procede de preparation de nouveaux conjugues associant par liaison covalente une enzyme et un anticorps
ATE278408T1 (de) Arsenic hexaoxide (as406) für die verwendung in krebs-therapie und pharmazeutische zubereitungen
DE69133068D1 (de) Tumor-zerstörende effekte von enterotoxinen und verwandten verbindungen
JPS572296A (en) Platinum organic complex, manufacture and malignant tumor medicine
IL97055A0 (en) Pharmaceutical compositions for sensitizing tumor cells comprising quinazolinedione derivatives
AU2027583A (en) Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medical composition using a such platinum-diamine complex for the treatment of cancer, as well as the thus shaped composition
SE8103404L (sv) Tennforeningar, sett att framstella dem, sett att framstella ett lekemedelspreparat under anvendning av en dylik tennforening for behandling av cancer samt det pa sa sett erhallna lekemedelspreparatet
HU9401656D0 (en) Pharmaceutical composition for treating tumours, containing creatine phosphate or phospho-enol-pyruvic acid
SE8103403L (sv) Germaniumforeningar, sett att framstella dem, sett att framstella ett lekemedelspreparat under anvendning av en dylik germaniumforening for behandling av cancer samt det pa sa sett erhallna lekemedelspreparatet
HUT43495A (en) Process for production and compound for treating of cancer and beningn tumor
WO1991019725A3 (en) Heterocyclic anthracyclione and anthracycline analogs
EP0341318A4 (en) Novel platinum (ii) complex, process for preparing the same, and therapeutic agent for malignant tumor
RU95120677A (ru) Способ лечения злокачественных опухолей
NO924781L (no) Heterocykliske antracyklion- og antracyklin-analoger
DE3177155D1 (de) Verwendung von 2-beta-d-ribofuranosylthiazol-4-carboxamiden zur herstellung von medikamenten zur behandlung von krebsartigen tumoren.
ES441357A1 (es) Procedimiento para la preparacion de 2-oxo-1-pirrolidin-ace-tamida.
RU92016483A (ru) Аналоги гетероциклических антрациклинов и антрациклионов
FR1048659A (fr) Acides n, n'-tétra-acétiques aliphatiques formant des complexes et leur procédé de préparation
SE7413146L (sv) Sett och beredningar for behandling av neurologiska sjukdomar.

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8100006-9

Effective date: 19940810

Format of ref document f/p: F