IT1190889B - Procedimento perfezionato per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina - Google Patents
Procedimento perfezionato per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidinaInfo
- Publication number
- IT1190889B IT1190889B IT22035/82A IT2203582A IT1190889B IT 1190889 B IT1190889 B IT 1190889B IT 22035/82 A IT22035/82 A IT 22035/82A IT 2203582 A IT2203582 A IT 2203582A IT 1190889 B IT1190889 B IT 1190889B
- Authority
- IT
- Italy
- Prior art keywords
- trimetossibenzil
- diamino
- pyrimidine
- preparation
- perfected procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU811869A HU187370B (en) | 1981-06-26 | 1981-06-26 | Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8222035A0 IT8222035A0 (it) | 1982-06-24 |
IT1190889B true IT1190889B (it) | 1988-02-24 |
Family
ID=10956594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22035/82A IT1190889B (it) | 1981-06-26 | 1982-06-24 | Procedimento perfezionato per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5838266A (fi) |
AT (1) | AT387961B (fi) |
AU (1) | AU547823B2 (fi) |
BE (1) | BE893611A (fi) |
CA (1) | CA1174679A (fi) |
CH (1) | CH648834A5 (fi) |
CS (1) | CS244908B2 (fi) |
DD (1) | DD202703A5 (fi) |
DK (1) | DK155434C (fi) |
ES (1) | ES8304949A1 (fi) |
FI (1) | FI76790C (fi) |
FR (1) | FR2508450B1 (fi) |
GB (1) | GB2104508B (fi) |
GR (1) | GR76159B (fi) |
HU (1) | HU187370B (fi) |
IE (1) | IE53466B1 (fi) |
IL (1) | IL66132A (fi) |
IT (1) | IT1190889B (fi) |
SE (1) | SE451133B (fi) |
SU (1) | SU1145929A3 (fi) |
YU (1) | YU42774B (fi) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2602507B1 (fr) * | 1986-08-08 | 1989-06-09 | Sanofi Pharma | Procede de preparation de diamino-2,4 benzyl-5 pyrimidines |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB743221A (en) * | 1953-05-26 | 1956-01-11 | Wellcome Found | Improvements in or relating to the manufacture of acrylonitriles |
DE1303727B (de) * | 1959-09-03 | 1976-02-05 | Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London | Alpha-Arylidensubstituierte Propioni-Irile |
NL122146C (fi) * | 1960-09-02 | |||
US4033962A (en) * | 1975-06-26 | 1977-07-05 | Hoffman-La Roche Inc. | 2,4-Diamino-pyrimidine derivatives and processes |
DE2635765C3 (de) * | 1976-08-09 | 1979-02-08 | Ludwig Heumann & Co Gmbh, 8500 Nuernberg | Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin |
US4115650A (en) * | 1976-11-17 | 1978-09-19 | Hoffmann-La Roche Inc. | Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines |
DE2730467A1 (de) * | 1977-07-06 | 1979-01-18 | Basf Ag | Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
-
1981
- 1981-06-26 HU HU811869A patent/HU187370B/hu not_active IP Right Cessation
-
1982
- 1982-06-23 BE BE1/10544A patent/BE893611A/fr not_active IP Right Cessation
- 1982-06-23 SE SE8203914A patent/SE451133B/sv not_active IP Right Cessation
- 1982-06-24 GB GB08218310A patent/GB2104508B/en not_active Expired
- 1982-06-24 GR GR68560A patent/GR76159B/el unknown
- 1982-06-24 IT IT22035/82A patent/IT1190889B/it active
- 1982-06-24 AT AT0244982A patent/AT387961B/de not_active IP Right Cessation
- 1982-06-24 IL IL66132A patent/IL66132A/xx unknown
- 1982-06-24 FI FI822268A patent/FI76790C/fi not_active IP Right Cessation
- 1982-06-24 SU SU823456294A patent/SU1145929A3/ru active
- 1982-06-24 CS CS824717A patent/CS244908B2/cs unknown
- 1982-06-25 DD DD82241097A patent/DD202703A5/de not_active IP Right Cessation
- 1982-06-25 FR FR8211151A patent/FR2508450B1/fr not_active Expired
- 1982-06-25 CH CH3908/82A patent/CH648834A5/de not_active IP Right Cessation
- 1982-06-25 ES ES513482A patent/ES8304949A1/es not_active Expired
- 1982-06-25 DK DK288082A patent/DK155434C/da not_active IP Right Cessation
- 1982-06-25 AU AU85346/82A patent/AU547823B2/en not_active Ceased
- 1982-06-25 IE IE1520/82A patent/IE53466B1/en not_active IP Right Cessation
- 1982-06-25 YU YU1385/82A patent/YU42774B/xx unknown
- 1982-06-25 CA CA000406060A patent/CA1174679A/en not_active Expired
- 1982-06-25 JP JP57109647A patent/JPS5838266A/ja active Pending
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