IS2103B - Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar - Google Patents

Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar

Info

Publication number
IS2103B
IS2103B IS4794A IS4794A IS2103B IS 2103 B IS2103 B IS 2103B IS 4794 A IS4794 A IS 4794A IS 4794 A IS4794 A IS 4794A IS 2103 B IS2103 B IS 2103B
Authority
IS
Iceland
Prior art keywords
densified
receptor inhibitors
ampa receptor
benzodiazepine derivatives
hydrogen
Prior art date
Application number
IS4794A
Other languages
English (en)
Other versions
IS4794A (is
Inventor
Csuzdi Ernese
ibrah βm Gizella
βn Tarnawa Istv
Andr βsi Ferenc
βs H βmori Tam
βndor Solyom S
βl Berzsenyi P
βn Ling Istv
Simay Antal
Horv βth Katalin
βrta Szôllosy M
G βl Melinda
Szentkuti Eszter
βn Pallagi Istv
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7785064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS2103(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of IS4794A publication Critical patent/IS4794A/is
Publication of IS2103B publication Critical patent/IS2103B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS4794A 1996-02-01 1998-07-06 Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar IS2103B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19604919A DE19604919A1 (de) 1996-02-01 1996-02-01 Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
PCT/DE1997/000234 WO1997028163A1 (de) 1996-02-01 1997-01-29 Kondensierte 2,3-benzodiazepin derivate und deren verwendung als ampa-rezeptoren-hemmer

Publications (2)

Publication Number Publication Date
IS4794A IS4794A (is) 1998-07-06
IS2103B true IS2103B (is) 2006-05-15

Family

ID=7785064

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4794A IS2103B (is) 1996-02-01 1998-07-06 Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar

Country Status (30)

Country Link
US (2) US6323197B1 (is)
EP (1) EP0888356B1 (is)
JP (1) JP4141499B2 (is)
KR (1) KR100465269B1 (is)
CN (1) CN1096464C (is)
AT (1) ATE214703T1 (is)
AU (1) AU724956B2 (is)
BG (1) BG63394B1 (is)
BR (1) BR9707335A (is)
CA (1) CA2245539C (is)
CZ (1) CZ289658B6 (is)
DE (2) DE19604919A1 (is)
DK (1) DK0888356T3 (is)
EE (1) EE04017B1 (is)
ES (1) ES2173435T3 (is)
HU (1) HU224636B1 (is)
IL (1) IL125480A (is)
IS (1) IS2103B (is)
MY (1) MY119140A (is)
NO (1) NO983510L (is)
NZ (1) NZ331187A (is)
PL (1) PL187128B1 (is)
PT (1) PT888356E (is)
RU (1) RU2179557C2 (is)
SK (1) SK283563B6 (is)
TR (1) TR199801485T2 (is)
TW (1) TW438801B (is)
UA (1) UA56157C2 (is)
WO (1) WO1997028163A1 (is)
ZA (1) ZA97848B (is)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9701325A1 (hu) * 1997-07-31 2000-08-28 Gyógyszerkutató Intézet Kft. Új 2,3-benzodiazepin-származékok
UA67749C2 (uk) * 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
WO2000001376A2 (en) * 1998-07-02 2000-01-13 Eisai Co., Ltd Pharmaceutical compositions and their uses for treatment of demyelinating disorders
US6887867B2 (en) * 2000-06-16 2005-05-03 Transgenomic, Inc. 5H-2,3-benzodiazepine antagonists of excitatory amino acid receptors
DE10041671C1 (de) 2000-08-10 2002-06-13 Schering Ag Verfahren zur Herstellung von Imidazo[1,2-c][2,3]benzodiazepinen sowie Phenylessigsäureester und Oxazol-Derivate als Zwischenprodukte bei deren Herstellung
WO2005113434A1 (en) * 2004-03-25 2005-12-01 William Marsh Rice University Functionalization of carbon nanotubes in acidic media
US20060166969A1 (en) * 2005-01-14 2006-07-27 Turski Lechoslaw A AMPA antagonists for the treatment of dizziness, including vertigo and Meniere's disorder
AR056080A1 (es) * 2005-09-23 2007-09-19 Schering Corp 7-[2-[4-(6-fluoro-3-metil-1,2-benciosoxazol-5-il)-1-piperazinil]etil]-2-(1-propinil)-7h-pirazol-[4,3-e]-[1,2,4]-triazol-[1,5-c] -pirimidin-5-amine
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
IE910939A1 (en) * 1990-04-13 1991-10-23 Neurosearch As Use of benzodiazepine compounds
US5891871A (en) 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
HU9600871D0 (en) * 1996-04-04 1996-05-28 Gyogyszerkutato Intezet New 2,3-benzodiazepine derivatives

Also Published As

Publication number Publication date
PL187128B1 (pl) 2004-05-31
UA56157C2 (uk) 2003-05-15
MY119140A (en) 2005-04-30
US20020052364A1 (en) 2002-05-02
DK0888356T3 (da) 2002-06-03
BR9707335A (pt) 1999-07-20
PT888356E (pt) 2002-09-30
KR19990082192A (ko) 1999-11-25
IL125480A (en) 2002-07-25
WO1997028163A1 (de) 1997-08-07
BG102658A (en) 1999-06-30
JP2000503997A (ja) 2000-04-04
BG63394B1 (bg) 2001-12-29
EP0888356A1 (de) 1999-01-07
DE59706686D1 (de) 2002-04-25
NZ331187A (en) 2000-01-28
CZ242798A3 (cs) 1999-01-13
HUP9901417A2 (hu) 1999-08-30
AU2502997A (en) 1997-08-22
AU724956B2 (en) 2000-10-05
DE19604919A1 (de) 1997-08-07
ZA97848B (en) 1997-08-04
RU2179557C2 (ru) 2002-02-20
NO983510D0 (no) 1998-07-30
ES2173435T3 (es) 2002-10-16
IS4794A (is) 1998-07-06
ATE214703T1 (de) 2002-04-15
HUP9901417A3 (en) 2001-11-28
CN1210538A (zh) 1999-03-10
SK283563B6 (sk) 2003-09-11
JP4141499B2 (ja) 2008-08-27
PL328224A1 (en) 1999-01-18
HU224636B1 (hu) 2005-12-28
EE04017B1 (et) 2003-04-15
US6323197B1 (en) 2001-11-27
CA2245539C (en) 2005-10-04
TW438801B (en) 2001-06-07
TR199801485T2 (xx) 1998-10-21
CZ289658B6 (cs) 2002-03-13
US6600036B2 (en) 2003-07-29
EP0888356B1 (de) 2002-03-20
CN1096464C (zh) 2002-12-18
KR100465269B1 (ko) 2005-04-14
SK103398A3 (en) 1999-01-11
NO983510L (no) 1998-09-30
CA2245539A1 (en) 1997-08-07
IL125480A0 (en) 1999-03-12
EE9800225A (et) 1998-12-15
HK1018782A1 (en) 2000-01-07

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