IN2014DN04226A - - Google Patents
Info
- Publication number
- IN2014DN04226A IN2014DN04226A IN4226DEN2014A IN2014DN04226A IN 2014DN04226 A IN2014DN04226 A IN 2014DN04226A IN 4226DEN2014 A IN4226DEN2014 A IN 4226DEN2014A IN 2014DN04226 A IN2014DN04226 A IN 2014DN04226A
- Authority
- IN
- India
- Prior art keywords
- subject
- depression
- effectiveness
- treating
- resistant
- Prior art date
Links
- 239000000090 biomarker Substances 0.000 abstract 3
- 239000000935 antidepressant agent Substances 0.000 abstract 2
- 238000011269 treatment regimen Methods 0.000 abstract 2
- JVJFIQYAHPMBBX-FNORWQNLSA-N (E)-4-hydroxynon-2-enal Chemical compound CCCCCC(O)\C=C\C=O JVJFIQYAHPMBBX-FNORWQNLSA-N 0.000 abstract 1
- JVJFIQYAHPMBBX-UHFFFAOYSA-N HNE Natural products CCCCCC(O)C=CC=O JVJFIQYAHPMBBX-UHFFFAOYSA-N 0.000 abstract 1
- 101001013648 Homo sapiens Methionine synthase Proteins 0.000 abstract 1
- 101001116314 Homo sapiens Methionine synthase reductase Proteins 0.000 abstract 1
- 101000587058 Homo sapiens Methylenetetrahydrofolate reductase Proteins 0.000 abstract 1
- 102100031551 Methionine synthase Human genes 0.000 abstract 1
- 102100024614 Methionine synthase reductase Human genes 0.000 abstract 1
- 102100029684 Methylenetetrahydrofolate reductase Human genes 0.000 abstract 1
- 101001030849 Rhinella marina Mesotocin receptor Proteins 0.000 abstract 1
- 208000028552 Treatment-Resistant Depressive disease Diseases 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 229940014144 folate Drugs 0.000 abstract 1
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 1
- 235000019152 folic acid Nutrition 0.000 abstract 1
- 239000011724 folic acid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161559541P | 2011-11-14 | 2011-11-14 | |
| PCT/US2012/065084 WO2013074676A2 (en) | 2011-11-14 | 2012-11-14 | Assays and methods for selecting a treatment regimen for a subject with depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN04226A true IN2014DN04226A (enrdf_load_stackoverflow) | 2015-05-22 |
Family
ID=47279072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4226DEN2014 IN2014DN04226A (enrdf_load_stackoverflow) | 2011-11-14 | 2012-11-14 |
Country Status (13)
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX354547B (es) | 2011-11-14 | 2018-03-09 | Alfasigma Spa | Ensayos y métodos para seleccionar un regimen de tratamiento para un sujeto con depresión. |
| BR112015022820A8 (pt) * | 2013-03-12 | 2019-11-26 | Nestec Sa | ensaio para selecionar um regime de tratamento para um indivíduo com depressão, uso de um composto compreendendo folato, composição e kit |
| SG11201507347QA (en) | 2013-03-15 | 2015-10-29 | Janssen Pharmaceutica Nv | Pharmaceutical composition of s-ketamine hydrochloride |
| US20150250813A1 (en) * | 2013-12-05 | 2015-09-10 | Buriva, LLC | Dietary supplement containing phospholipid-dha, folate, and n-acetyl-l-cysteine |
| US9549937B2 (en) * | 2013-12-05 | 2017-01-24 | Burvia, LLC. | Composition containing phospholipid-DHA and folate |
| US9610302B2 (en) * | 2013-12-05 | 2017-04-04 | Buriva, LLC. | Composition containing phospholipid-DHA and B vitamins |
| MA39485A (fr) * | 2014-03-05 | 2015-09-11 | Takeda Pharmaceuticals Co | Méthode de traitement de la dépression et du trouble dépressif majeur |
| WO2015136446A1 (en) * | 2014-03-11 | 2015-09-17 | Nestec S.A. | Methods for selecting antidepressant drug therapy to treat depression |
| KR101588119B1 (ko) * | 2014-05-16 | 2016-01-25 | 동아대학교 산학협력단 | Ｓｌｃ6ａ3 유전자의 다형성 소위성과 이를 이용한 ｄｎａ 타이핑 키트 및 상기 유전자 관련 질병의 진단키트 |
| EP3179993B1 (en) | 2014-08-13 | 2021-01-20 | Janssen Pharmaceutica NV | Esketamine for use in a method for the treatment of depression |
| US20160074340A1 (en) | 2014-09-15 | 2016-03-17 | Janssen Pharmaceutica Nv | VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION |
| CN105671130A (zh) * | 2014-11-18 | 2016-06-15 | 武汉白原科技有限公司 | 一种心理性格检测试剂盒和方法 |
| US20160203591A1 (en) * | 2015-01-09 | 2016-07-14 | Umm Al-Qura University | System and process for monitoring the quality of food in a refrigerator |
| CN104655705B (zh) * | 2015-02-12 | 2017-03-08 | 江苏省原子医学研究所 | 一种用毛细管电泳快速检测生物样本中儿茶酚氧甲基转移酶comt活性的方法 |
| CN104789668A (zh) * | 2015-04-10 | 2015-07-22 | 浙江博惠生物科技有限公司 | 一种叶酸代谢能力评估的检测位点rs1801394的检测PCR扩增引物和单碱基延伸引物 |
| WO2016168685A1 (en) * | 2015-04-17 | 2016-10-20 | Mayo Foundation For Medical Education And Research | Modulating the aryl hydrocarbon receptor system to treat major depressive disorder |
| WO2016176458A1 (en) * | 2015-04-28 | 2016-11-03 | Proove Biosciences, Inc. | System and method for processing genotype information relating to opiod risk |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| WO2016191507A1 (en) * | 2015-05-25 | 2016-12-01 | Arthus Biosystems Llc | Use of fluorescence for the quick and easy determination of s-adenosylmethionine, s-adenosylhomocysteine and homocysteine |
| US11313868B2 (en) | 2016-06-14 | 2022-04-26 | Board Of Regents, The University Of Texas System | Methods of detecting anti-folic acid antibodies and uses thereof |
| JP2019530477A (ja) * | 2016-09-26 | 2019-10-24 | プレシジョン・メディスン・ホールディングス・プロプライエタリー・リミテッド | 精神分裂病および分裂情動性精神病の診断、予後、および処置 |
| CN107245527A (zh) * | 2017-07-25 | 2017-10-13 | 重庆京因生物科技有限责任公司 | Mtrr基因多态性快速检测的引物、分子信标、试剂盒及其检测方法 |
| WO2019027568A1 (en) * | 2017-08-02 | 2019-02-07 | Glaxosmithkline Consumer Healthcare Holdings (Us) Llc | PORTABLE DEVICE AND APPLICATION FOR BEHAVIORAL CARRIER |
| US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
| KR20200113197A (ko) | 2017-12-22 | 2020-10-06 | 얀센 파마슈티칼즈, 인코포레이티드 | 우울증 치료를 위한 에스케타민 |
| CN108251522B (zh) * | 2018-04-09 | 2020-11-27 | 江苏硕世生物科技股份有限公司 | 人类mthfr和mtrr基因检测试剂盒及其用途 |
| CN108642138B (zh) * | 2018-05-02 | 2021-11-30 | 广东药科大学 | 一种检测叶酸代谢相关基因遗传信息的方法及试剂盒 |
| EP3788644A4 (en) | 2018-05-03 | 2023-03-01 | L. Pierre De Rochemont | HIGH-SPEED/LOW-POWER COMPUTER CENTERS AND SERVER NETWORKS |
| WO2019236734A1 (en) | 2018-06-05 | 2019-12-12 | De Rochemont L Pierre | Module with high peak bandwidth i/o channels |
| CN108823299A (zh) * | 2018-06-11 | 2018-11-16 | 苏州艾达康医疗科技有限公司 | 一种抑郁症用药相关基因的检测方法及试剂盒 |
| SG11202102098WA (en) * | 2018-09-03 | 2021-04-29 | Visby Medical Inc | Devices and methods for antibiotic susceptibility testing |
| CN114126595A (zh) | 2019-03-05 | 2022-03-01 | 杨森制药公司 | 用于治疗抑郁症的艾司氯胺酮 |
| WO2020232125A1 (en) | 2019-05-14 | 2020-11-19 | Prometheus Biosciences, Inc. | Tl1a patient selection methods, systems, and devices |
| CN110148461B (zh) * | 2019-06-26 | 2021-09-21 | 周建勋 | 用于多参数测量的模块切换系统 |
| CN110693507A (zh) * | 2019-08-30 | 2020-01-17 | 中国民用航空飞行学院 | 一种民航飞行学员心理健康测试和心理援助系统 |
| CN111351945B (zh) * | 2020-03-18 | 2021-04-23 | 东南大学 | 维生素d结合蛋白作为标志物在精神疾病抑郁症诊断中的应用 |
| US20220165379A1 (en) * | 2020-11-24 | 2022-05-26 | Genomind, Inc. | Methods and systems for reporting patient- and drug-specific medical data |
| CN116103385B (zh) * | 2021-11-11 | 2024-11-15 | 深圳理工大学 | 一种预测抑郁障碍患者对治疗反应的基因诊断试剂盒和系统 |
| CN116298233A (zh) * | 2022-03-16 | 2023-06-23 | 昱言科技(北京)有限公司 | 用于诊断双相障碍的生物标记物 |
| WO2023220213A1 (en) * | 2022-05-11 | 2023-11-16 | Higgins Evelyn | Methods for providing a personalized therapeutic treatment regime for addictions |
Family Cites Families (93)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US548257A (en) | 1895-10-22 | Hay rake and loader | ||
| US3837376A (en) | 1971-06-01 | 1974-09-24 | Metropolitan Pathology Labor I | Blood serum collection tube and method |
| US4336185A (en) | 1976-03-02 | 1982-06-22 | Rohm And Haas Company | Folic acid derivatives |
| US4120448A (en) | 1977-06-08 | 1978-10-17 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing apparatus with automatically positioned collection port |
| US4656035A (en) | 1984-12-21 | 1987-04-07 | University Of Tennessee Research Corporation | Method of separating blood platelets |
| US4946773A (en) | 1985-12-23 | 1990-08-07 | President And Fellows Of Harvard College | Detection of base pair mismatches using RNAase A |
| US5322770A (en) | 1989-12-22 | 1994-06-21 | Hoffman-Laroche Inc. | Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription |
| US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| ATE92538T1 (de) | 1988-01-21 | 1993-08-15 | Genentech Inc | Verstaerkung und nachweis von nukleinsaeuresequenzen. |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| WO1989010414A1 (en) | 1988-04-28 | 1989-11-02 | Robert Bruce Wallace | AMPLIFIED SEQUENCE POLYMORPHISMS (ASPs) |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US5925525A (en) | 1989-06-07 | 1999-07-20 | Affymetrix, Inc. | Method of identifying nucleotide differences |
| GB2236186B (en) | 1989-08-22 | 1994-01-05 | Finnigan Mat Gmbh | Process and device for laser desorption of analyte molecular ions, especially of biomolecules |
| US5045694A (en) | 1989-09-27 | 1991-09-03 | The Rockefeller University | Instrument and method for the laser desorption of ions in mass spectrometry |
| US6013431A (en) | 1990-02-16 | 2000-01-11 | Molecular Tool, Inc. | Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators |
| US5846710A (en) | 1990-11-02 | 1998-12-08 | St. Louis University | Method for the detection of genetic diseases and gene sequence variations by single nucleotide primer extension |
| EP0834576B1 (en) | 1990-12-06 | 2002-01-16 | Affymetrix, Inc. (a Delaware Corporation) | Detection of nucleic acid sequences |
| US5169766A (en) | 1991-06-14 | 1992-12-08 | Life Technologies, Inc. | Amplification of nucleic acid molecules |
| US5994069A (en) | 1996-01-24 | 1999-11-30 | Third Wave Technologies, Inc. | Detection of nucleic acids by multiple sequential invasive cleavages |
| EP1347493A3 (en) | 1993-05-28 | 2005-11-23 | Baylor College Of Medicine | Method and apparatus for desorption and ionization of analytes |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US6136540A (en) | 1994-10-03 | 2000-10-24 | Ikonisys Inc. | Automated fluorescence in situ hybridization detection of genetic abnormalities |
| US5952172A (en) | 1993-12-10 | 1999-09-14 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5851770A (en) | 1994-04-25 | 1998-12-22 | Variagenics, Inc. | Detection of mismatches by resolvase cleavage using a magnetic bead support |
| GB9410620D0 (en) | 1994-05-26 | 1994-07-13 | Univ Mcgill | cDNA for human mehylenetetrahydrofolate reductase |
| US6566065B1 (en) | 1994-05-26 | 2003-05-20 | Mcgill University | Method of diagnosing schizophrenia by detecting a mutation in the (MTHFR) gene |
| US6379897B1 (en) | 2000-11-09 | 2002-04-30 | Nanogen, Inc. | Methods for gene expression monitoring on electronic microarrays |
| US5849483A (en) | 1994-07-28 | 1998-12-15 | Ig Laboratories, Inc. | High throughput screening method for sequences or genetic alterations in nucleic acids |
| US5866337A (en) | 1995-03-24 | 1999-02-02 | The Trustees Of Columbia University In The City Of New York | Method to detect mutations in a nucleic acid using a hybridization-ligation procedure |
| US5704888A (en) | 1995-04-14 | 1998-01-06 | Cobe Laboratories, Inc. | Intermittent collection of mononuclear cells in a centrifuge apparatus |
| US5968740A (en) | 1995-07-24 | 1999-10-19 | Affymetrix, Inc. | Method of Identifying a Base in a Nucleic Acid |
| US6264970B1 (en) | 1996-06-26 | 2001-07-24 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
| US5928870A (en) | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6465611B1 (en) | 1997-02-25 | 2002-10-15 | Corixa Corporation | Compounds for immunotherapy of prostate cancer and methods for their use |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| CA2303206A1 (en) | 1997-09-10 | 1999-03-18 | University Of Maryland, Baltimore | Method of amplifying dna and rna mismatch cleavage products |
| ATE369135T1 (de) * | 1998-04-24 | 2007-08-15 | Scarista Ltd | Behandlung von depression und zusammensetzungen dazu |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| ID27504A (id) | 1998-10-01 | 2001-04-12 | Novartis Ag | Formulasi oral baru |
| US6395481B1 (en) | 1999-02-16 | 2002-05-28 | Arch Development Corp. | Methods for detection of promoter polymorphism in a UGT gene promoter |
| US7429466B2 (en) | 2000-01-24 | 2008-09-30 | Hypromatrix, Inc | Methods and arrays for detecting biological molecules |
| WO2001055454A1 (en) | 2000-01-28 | 2001-08-02 | Althea Technologies, Inc. | Methods for analysis of gene expression |
| JP4382322B2 (ja) | 2000-03-09 | 2009-12-09 | カリディアンビーシーティ、インコーポレイテッド | 体外血液処理装置 |
| AU2001253618A1 (en) | 2000-04-21 | 2001-11-07 | Arch Development Corporation | Flavopiridol drug combinations and methods with reduced side effects |
| DE10022510A1 (de) | 2000-05-10 | 2001-11-15 | Basf Ag | Zusammensetzungen enthaltend Folsäure und reduziertes Folat |
| US6355433B1 (en) | 2000-06-02 | 2002-03-12 | Dna Sciences, Inc. | Determination of nucleotide sequence variations through limited primer extension |
| EP1304324B1 (en) | 2000-07-18 | 2007-10-03 | Dainippon Sumitomo Pharma Co., Ltd. | Serotonin reuptake inhibitors |
| WO2002059375A2 (en) | 2001-01-26 | 2002-08-01 | University Of Chicago | Determination of ugt2b7 gene polymorphisms for predicting ugt2b7 substrate toxicity and for optimising drug dosage |
| US6720003B2 (en) | 2001-02-16 | 2004-04-13 | Andrx Corporation | Serotonin reuptake inhibitor formulations |
| WO2002086168A1 (en) | 2001-04-19 | 2002-10-31 | Ciphergen Biosystems, Inc. | Biomolecule characterization using mass spectrometry and affinity tags |
| US20030100476A1 (en) | 2001-05-11 | 2003-05-29 | Weinberger Daniel R. | Effect of COMT genotype on frontal lobe function |
| US7074901B2 (en) | 2001-05-25 | 2006-07-11 | Serono Genetics Institute S.A. | Isolated human vCOL16A1 polypeptide and fragments thereof |
| US7112408B2 (en) | 2001-06-08 | 2006-09-26 | The Brigham And Women's Hospital, Inc. | Detection of ovarian cancer based upon alpha-haptoglobin levels |
| US20030013208A1 (en) | 2001-07-13 | 2003-01-16 | Milagen, Inc. | Information enhanced antibody arrays |
| WO2003017177A2 (en) | 2001-08-13 | 2003-02-27 | Beyong Genomics, Inc. | Method and system for profiling biological systems |
| UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| IL163645A0 (en) | 2002-02-21 | 2005-12-18 | Idgene Pharmaceuticals Ltd | Association of snps in the comt locus and neighboring loci with schizophrenia, bipolar disorder, breast cancer and colorectal cancer |
| US20030215858A1 (en) | 2002-04-08 | 2003-11-20 | Baylor College Of Medicine | Enhanced gene expression system |
| US7241281B2 (en) | 2002-04-08 | 2007-07-10 | Thermogenesis Corporation | Blood component separation method and apparatus |
| US20030194711A1 (en) | 2002-04-10 | 2003-10-16 | Matthew Zapala | System and method for analyzing gene expression data |
| WO2003091735A1 (en) | 2002-04-23 | 2003-11-06 | Millipore Corporation | Sample preparation of biological fluids for proteomic applications |
| US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
| CA2415154C (en) | 2002-12-24 | 2009-06-16 | Biovail Laboratories Inc. | Modified release formulations of selective serotonin re-uptake inhibitors |
| US20040203034A1 (en) | 2003-01-03 | 2004-10-14 | The University Of Chicago | Optimization of cancer treatment with irinotecan |
| CN102772357B (zh) | 2003-03-31 | 2014-12-31 | 泰坦医药品公司 | 用于持续释放多巴胺受体激动剂的可植入聚合物装置 |
| US20050054688A1 (en) | 2003-08-08 | 2005-03-10 | Pfizer Inc | Selective serotonin reuptake inhibitors in the treatment of disease |
| US20050069936A1 (en) | 2003-09-26 | 2005-03-31 | Cornelius Diamond | Diagnostic markers of depression treatment and methods of use thereof |
| WO2005094896A2 (en) | 2004-03-26 | 2005-10-13 | Baylor University | Targeted serotonin reuptake inhibitors |
| JP2005312435A (ja) | 2004-03-29 | 2005-11-10 | Kazuhito Rokutan | うつ病の評価方法 |
| WO2006099164A2 (en) | 2005-03-10 | 2006-09-21 | Applera Corporation | Methods for multiplex amplification |
| US7972770B2 (en) | 2005-08-16 | 2011-07-05 | Memorial Sloan-Kettering Cancer Center | Methods of detection of cancer using peptide profiles |
| JP2009518035A (ja) | 2005-12-06 | 2009-05-07 | ザ ジェネラル ホスピタル コーポレイション | 疼痛感受性および慢性化に関する診断法およびテトラヒドロビオプテリン関連障害に関する診断法 |
| US20080064702A1 (en) | 2006-09-08 | 2008-03-13 | Charalambos Antoniades | Use of folates for the prevention and treatment of vascular diseases |
| US8268347B1 (en) | 2006-10-24 | 2012-09-18 | Aradigm Corporation | Dual action, inhaled formulations providing both an immediate and sustained release profile |
| US20100273153A1 (en) | 2006-11-29 | 2010-10-28 | Boris Tabakoff | Genetic diagnosis of depression |
| WO2008086579A1 (en) | 2007-01-19 | 2008-07-24 | Queensland University Of Technology | Diagnostic methods and agents |
| US7947662B2 (en) | 2008-02-20 | 2011-05-24 | Gnosis S.P.A. | Folates, compositions and uses thereof |
| US20090307180A1 (en) | 2008-03-19 | 2009-12-10 | Brandon Colby | Genetic analysis |
| WO2009131643A1 (en) | 2008-04-21 | 2009-10-29 | Monabio, Inc. | Immunoassay for specific determination of s-adenosymethionine and analogs thereof in biological samples |
| CN102202676A (zh) | 2008-06-21 | 2011-09-28 | 肯贝尔有限责任公司 | 作为治疗方法的dna-导引的镇痛剂化合物的个体化 |
| WO2010060189A1 (en) | 2008-11-03 | 2010-06-03 | Newlab Clinical Research Inc. | Allele-allele interactions of mthfr gene variants, and uses thereof in predicting disease risk |
| EP2435586A4 (en) * | 2009-05-29 | 2012-12-26 | Genomind Llc | METHODS OF EVALUATION AND TREATMENT OF DEPRESSION VIA USE OF ANALYSIS OF SIMPLE NUCLEOTIDE POLYMORPHISMS |
| AU2010300475A1 (en) | 2009-09-30 | 2012-05-03 | The Regents Of The University Of California | Cofactors and methods for use for individuals |
| WO2012128799A2 (en) * | 2010-12-03 | 2012-09-27 | General Hospital Corporation, The | Treating schizophrenia |
| KR20120092993A (ko) | 2011-02-14 | 2012-08-22 | 지엘팜텍 주식회사 | 티아넵틴 또는 이의 약제학적으로 허용되는 염을 포함하는 경구투여용 서방성 정제 |
| CA2829791A1 (en) | 2011-03-28 | 2012-10-04 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Sustained-release injectable formulation |
| WO2012177746A1 (en) | 2011-06-21 | 2012-12-27 | Global Healthcare Focus, Llc | Methods of preventing or treating disease states related to certain metabolic abnormalities |
| US20160058766A1 (en) * | 2011-11-14 | 2016-03-03 | Nestec S.A. | Assays and methods for selecting a treatment regimen for a subject with depression |
| MX354547B (es) * | 2011-11-14 | 2018-03-09 | Alfasigma Spa | Ensayos y métodos para seleccionar un regimen de tratamiento para un sujeto con depresión. |
-
2012
- 2012-11-14 MX MX2014005786A patent/MX354547B/es active IP Right Grant
- 2012-11-14 BR BR112014011491A patent/BR112014011491A2/pt active Search and Examination
- 2012-11-14 AU AU2012340015A patent/AU2012340015B2/en not_active Ceased
- 2012-11-14 WO PCT/US2012/065084 patent/WO2013074676A2/en active Application Filing
- 2012-11-14 EP EP12795214.1A patent/EP2780467B1/en active Active
- 2012-11-14 CA CA2855640A patent/CA2855640C/en active Active
- 2012-11-14 RU RU2014124121A patent/RU2622082C2/ru active
- 2012-11-14 IN IN4226DEN2014 patent/IN2014DN04226A/en unknown
- 2012-11-14 CN CN201280065415.6A patent/CN104053785A/zh active Pending
- 2012-11-14 KR KR1020147016192A patent/KR102035877B1/ko not_active Expired - Fee Related
- 2012-11-14 JP JP2014541420A patent/JP6285865B2/ja not_active Expired - Fee Related
-
2013
- 2013-03-07 US US13/789,075 patent/US9540691B2/en active Active
- 2013-03-12 US US13/796,362 patent/US9546401B2/en active Active
-
2014
- 2014-05-01 IL IL232407A patent/IL232407B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP2780467A2 (en) | 2014-09-24 |
| CA2855640C (en) | 2020-03-10 |
| CA2855640A1 (en) | 2013-05-23 |
| US9546401B2 (en) | 2017-01-17 |
| WO2013074676A2 (en) | 2013-05-23 |
| WO2013074676A3 (en) | 2013-08-15 |
| US20130267523A1 (en) | 2013-10-10 |
| NZ624231A (en) | 2016-10-28 |
| EP2780467B1 (en) | 2018-10-17 |
| US9540691B2 (en) | 2017-01-10 |
| JP6285865B2 (ja) | 2018-02-28 |
| AU2012340015B2 (en) | 2017-09-21 |
| IL232407A0 (en) | 2014-06-30 |
| JP2015508281A (ja) | 2015-03-19 |
| MX354547B (es) | 2018-03-09 |
| RU2622082C2 (ru) | 2017-06-09 |
| RU2014124121A (ru) | 2015-12-27 |
| IL232407B (en) | 2019-03-31 |
| BR112014011491A2 (pt) | 2017-05-09 |
| HK1202590A1 (en) | 2015-10-02 |
| KR20140100524A (ko) | 2014-08-14 |
| US20130172361A1 (en) | 2013-07-04 |
| AU2012340015A1 (en) | 2014-05-22 |
| CN104053785A (zh) | 2014-09-17 |
| KR102035877B1 (ko) | 2019-10-23 |
| MX2014005786A (es) | 2014-08-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014DN04226A (enrdf_load_stackoverflow) | ||
| MX2014003153A (es) | Prediccion de riesgo de evento cardiovascular y usos del mismo. | |
| GB201317477D0 (en) | Methods, compositions and kits for determing the presence/absnece of a variant nucleic acid sequence | |
| WO2015094995A3 (en) | Gene signature biomarkers of tumor response to pd-1 antagonists | |
| BR112012011230A2 (pt) | fatores de risco e previsão de infarto do miocárdio | |
| BR112013003391A2 (pt) | biomarcadores de câncer pancreático e usos dos mesmos | |
| PH12018550037A1 (en) | Quencher containing water-soluble polymer-conjugated nanomaterial and use thereof | |
| MX2013012183A (es) | Terapia de combinacion de hsp90. | |
| NZ620799A (en) | Molecular diagnostic test for cancer | |
| WO2013009655A3 (en) | Uses of labeled hsp90 inhibitors | |
| BRPI0919882A8 (pt) | Métodos para avaliar padrões de rna | |
| BR112012029281A2 (pt) | anticorpo trop-2 anti-humano tendo atividade anti-tumor in vivo | |
| BRPI0816393A2 (pt) | Método para determinar o número de cópias relativo de uma sequência de polinucleotídeo alvo em um genoma de um indivíduo | |
| BR112013030606A2 (pt) | biomarcadores para terapia inibidora de hedgehog | |
| EA201600085A1 (ru) | Набор для обнаружения соевого события syht0h2 | |
| WO2015172085A3 (en) | Biomarkers for response to pi3k inhibitors | |
| WO2015094996A3 (en) | Pd-l1 gene signature biomarkers of tumor response to pd-1 antagonists | |
| EA201590630A1 (ru) | Способы лечения и диагностики, связанные с лизилоксидазоподобным белком 2 (loxl2) | |
| EA030186B9 (ru) | Способ проведения количественных анализов | |
| BR112012009262A2 (pt) | ''método para inibir a proliferação de células de câncer positivo para ar em um indivíduo diagnosticado com,ou qual se suspeita que tenha cânce positivo para ar e método para identificar se um indivíduo é um candidato para tratamento com uma composiçâo | |
| ATE504002T1 (de) | Erkennung und vorhersage von frühgeburten | |
| BRPI0519570A2 (pt) | mÉtodo de determinaÇço de faixa de dose de uma warfarina para um indivÍduo, kit para determinaÇço da faixa de dose de uma warfarina, oligonucleotÍdeo ou complemento do mesmo, e, arranjo de oligonucleotÍdeos | |
| UY35075A (es) | Biomarcadores predictivos de la respuesta clínica al acetato de glatirámero | |
| WO2013106844A3 (en) | Methods and compositions for the treatment and diaginosis of pancreatic cancer | |
| BR112012021411A2 (pt) | mutações braf que conferem resistência a inibidores braf. |