BR112014020213A2 - biomarcadores para o diagnóstico, o prognóstico, a avaliação e a estratificação de terapia de síncope - Google Patents

biomarcadores para o diagnóstico, o prognóstico, a avaliação e a estratificação de terapia de síncope

Info

Publication number
BR112014020213A2
BR112014020213A2 BR112014020213A BR112014020213A BR112014020213A2 BR 112014020213 A2 BR112014020213 A2 BR 112014020213A2 BR 112014020213 A BR112014020213 A BR 112014020213A BR 112014020213 A BR112014020213 A BR 112014020213A BR 112014020213 A2 BR112014020213 A2 BR 112014020213A2
Authority
BR
Brazil
Prior art keywords
stratification
prognosis
diagnosis
evaluation
biomarkers
Prior art date
Application number
BR112014020213A
Other languages
English (en)
Inventor
Fedorowski Artur
Struck Joachim
Melander Olle
Original Assignee
Brahms Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brahms Gmbh filed Critical Brahms Gmbh
Publication of BR112014020213A2 publication Critical patent/BR112014020213A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/322—Orthostatic hypertension or syncope
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

resumo patente de invenção: "biomarcadores para o diagnóstico, o prognóstico, a avaliação e a estratificação de terapia de síncope". a presente invenção refere-se a um processo para o diagnóstico e/ou o prognóstico e/ou a avaliação e/ou a estratificação de terapia de síncope em um paciente o processo compreendendo: a determinação do nível de pelo menos um biomarcador selecionado do grupo que consiste em proet-1, proadm, proanp, probnp, proavp e pct ou um fragmento de pelo menos 12 aminoácidos do mesmo, em uma amostra de um fluido corporal do dito paciente, a correlação do dito nível de pelo menos um biomarcador ou fragmentos do mesmo com o diagnóstico e/ou o prognóstico e/ou a avaliação e/ou a estratificação de terapia de síncope.
BR112014020213A 2012-04-26 2013-04-12 biomarcadores para o diagnóstico, o prognóstico, a avaliação e a estratificação de terapia de síncope BR112014020213A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20120002935 EP2657707A1 (en) 2012-04-26 2012-04-26 Biomakers for the diagnosis, prognosis, assessment and therapy stratification syncope
PCT/EP2013/001081 WO2013159872A1 (en) 2012-04-26 2013-04-12 Biomarkers for the diagnosis, prognosis, assessment and therapy stratification of syncope

Publications (1)

Publication Number Publication Date
BR112014020213A2 true BR112014020213A2 (pt) 2017-07-04

Family

ID=48142720

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014020213A BR112014020213A2 (pt) 2012-04-26 2013-04-12 biomarcadores para o diagnóstico, o prognóstico, a avaliação e a estratificação de terapia de síncope

Country Status (7)

Country Link
US (1) US20150119271A1 (pt)
EP (2) EP2657707A1 (pt)
JP (1) JP6062532B2 (pt)
CN (1) CN104115012B (pt)
BR (1) BR112014020213A2 (pt)
RU (1) RU2613885C2 (pt)
WO (1) WO2013159872A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2648385C (en) 2006-04-04 2020-09-01 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
WO2010144358A1 (en) 2009-06-08 2010-12-16 Singulex, Inc. Highly sensitive biomarker panels
WO2014116708A1 (en) * 2013-01-22 2014-07-31 Singulex, Inc. Endothelin in the diagnosis of cardiac disease
AU2017230706A1 (en) * 2016-03-09 2018-09-27 Biomerica, Inc. Compositions, devices, and methods of functional dyspepsia sensitivity testing
AU2017235312A1 (en) * 2016-03-15 2018-10-04 Biomerica, Inc. Compositions, devices, and methods of fibromyalgia sensitivity testing
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US11931207B2 (en) 2018-12-11 2024-03-19 Eko.Ai Pte. Ltd. Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device
CN117275737B (zh) * 2023-11-22 2024-02-23 首都医科大学宣武医院 一种直立性低血压智能诊疗方法、设备及可存储介质

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5993811A (en) * 1997-02-03 1999-11-30 Biology Associates, Llc Method and compositions for preventing and treating the systemic inflammatory response syndrome including sepsis
CN1339466A (zh) * 2000-08-21 2002-03-13 上海博德基因开发有限公司 一种新的多肽——人内皮素受体b相似蛋白23.65和编码这种多肽的多核苷酸
DE10316583A1 (de) * 2003-04-10 2004-10-28 B.R.A.H.M.S Aktiengesellschaft Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung
US20060099608A1 (en) * 2004-03-29 2006-05-11 Medstar Research Institute Methods of diagnosing cardiovascular disease
JP5757873B2 (ja) * 2008-10-31 2015-08-05 ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング 代謝症候群、心血管疾患及び／又はインスリン耐性に関連する障害の診断、予後、モニターリング及び治療追跡のためのインビトロ方法
EP2427764B1 (en) * 2009-05-05 2017-07-26 B.R.A.H.M.S GmbH Vasoactive hormone-based stratification of patients suffering from diseases related to endothelial function/dysfunction
RU2409310C1 (ru) * 2009-10-26 2011-01-20 Федеральное государственное учреждение "Государственный научно-исследовательский центр профилактической медицины Федерального агентства по высокотехнологичной медицинской помощи" Способ диагностики ортостатической гипотензии

Also Published As

Publication number Publication date
JP2015519550A (ja) 2015-07-09
CN104115012A (zh) 2014-10-22
RU2613885C2 (ru) 2017-03-21
EP2657707A1 (en) 2013-10-30
EP2841949A1 (en) 2015-03-04
WO2013159872A8 (en) 2014-08-07
EP2841949B1 (en) 2017-11-22
CN104115012B (zh) 2016-02-10
WO2013159872A1 (en) 2013-10-31
RU2014136453A (ru) 2016-06-20
JP6062532B2 (ja) 2017-01-18
US20150119271A1 (en) 2015-04-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06U Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements