MX2018012580A - Métodos y kits para el diagnóstico y la estratificación de riesgo en pacientes con isquemia. - Google Patents
Métodos y kits para el diagnóstico y la estratificación de riesgo en pacientes con isquemia.Info
- Publication number
- MX2018012580A MX2018012580A MX2018012580A MX2018012580A MX2018012580A MX 2018012580 A MX2018012580 A MX 2018012580A MX 2018012580 A MX2018012580 A MX 2018012580A MX 2018012580 A MX2018012580 A MX 2018012580A MX 2018012580 A MX2018012580 A MX 2018012580A
- Authority
- MX
- Mexico
- Prior art keywords
- ischemia
- methods
- diagnosis
- kits
- patients
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Abstract
La invención se refiere a métodos para el diagnóstico de isquemia o daño tisular isquémico, métodos para la predicción de la evolución de la isquemia en un paciente que ha padecido un suceso isquémico, para la determinación del pronóstico de un paciente que ha padecido un suceso isquémico y para la determinación del riesgo de que un paciente que padece enfermedad coronaria estable padezca un suceso isquémico recurrente basado en la detección de los niveles de Apo J glicosilada. La invención también se refiere a un método para la determinación de los niveles de Apo J glicosilada en una muestra.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16382167.1A EP3232200A1 (en) | 2016-04-12 | 2016-04-12 | Methods and kits for the diagnosis and risk stratification of patients with ischemia |
PCT/EP2017/058768 WO2017178521A1 (en) | 2016-04-12 | 2017-04-12 | Methods and kits for the diagnosis and risk stratification of patients with ischemia |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018012580A true MX2018012580A (es) | 2019-02-25 |
Family
ID=56008566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018012580A MX2018012580A (es) | 2016-04-12 | 2017-04-12 | Métodos y kits para el diagnóstico y la estratificación de riesgo en pacientes con isquemia. |
Country Status (14)
Country | Link |
---|---|
US (1) | US11486884B2 (es) |
EP (2) | EP3232200A1 (es) |
JP (1) | JP7075894B2 (es) |
KR (1) | KR102344344B1 (es) |
CN (1) | CN109154620B (es) |
AU (1) | AU2017251355A1 (es) |
BR (1) | BR112018070971A2 (es) |
CA (1) | CA3020666A1 (es) |
IL (1) | IL262245B (es) |
MA (1) | MA44658A (es) |
MX (1) | MX2018012580A (es) |
RU (1) | RU2750035C2 (es) |
SG (1) | SG11201808820QA (es) |
WO (1) | WO2017178521A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11202103124WA (en) * | 2018-10-23 | 2021-04-29 | Glycardial Diagnostics S L | Antibodies specific for glycosylated apoj and uses thereof |
EP3890830A2 (en) * | 2018-12-05 | 2021-10-13 | Glycardial Diagnostics, S.L. | Methods and compositions for the prevention and/or treatment of ischemia and of ischemia/reperfusion injury |
KR102158726B1 (ko) | 2019-04-17 | 2020-09-22 | 한림대학교 산학협력단 | Itpr3 유전자 업스트림의 유전자간 영역을 포함하는 지연성 허혈 진단용 dna 메틸화 마커 조성물 |
KR102281657B1 (ko) | 2019-12-23 | 2021-07-26 | 한림대학교 산학협력단 | 지연성 허혈 진단을 위한 cdhr5 유전자 과메틸화 마커 |
KR102281644B1 (ko) | 2019-12-23 | 2021-07-23 | 한림대학교 산학협력단 | 지연성 허혈 진단을 위한 insr 유전자 과메틸화 마커 |
KR102312534B1 (ko) | 2019-12-31 | 2021-10-13 | 한림대학교 산학협력단 | 뇌척수액 유래 미토콘드리아 마커를 이용한 지연성 허혈 진단 방법 |
KR102318236B1 (ko) | 2020-02-18 | 2021-10-26 | 한림대학교 산학협력단 | 혈중 코펩틴의 농도를 이용한 지연성 뇌허혈 진단 방법 |
KR102336507B1 (ko) | 2020-02-21 | 2021-12-06 | 한림대학교 산학협력단 | 국소뇌산소포화도를 이용한 지연성 뇌허혈 진단 방법 |
KR102369155B1 (ko) | 2020-07-07 | 2022-02-28 | 한림대학교 산학협력단 | 근적외선 분광분석법을 이용한 지연성 뇌허혈 진단 방법 |
KR102473350B1 (ko) | 2020-09-11 | 2022-12-05 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 racgap1 유전자 과메틸화 마커 |
KR102473349B1 (ko) | 2020-09-11 | 2022-12-05 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 kifap3 유전자 과메틸화 마커 |
KR102473348B1 (ko) | 2020-09-11 | 2022-12-05 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 kif3a 유전자 과메틸화 마커 |
KR102496589B1 (ko) | 2020-09-11 | 2023-02-03 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 vhl 유전자 과메틸화 마커 |
KR102477501B1 (ko) | 2020-09-15 | 2022-12-14 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 alb 유전자 저메틸화 마커 |
KR102477500B1 (ko) | 2020-09-15 | 2022-12-14 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 oprm1 유전자 과메틸화 마커 |
KR102477502B1 (ko) | 2020-09-15 | 2022-12-14 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 il5 유전자 저메틸화 마커 |
KR102466956B1 (ko) | 2020-11-05 | 2022-11-11 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 dapk1 바이오마커 |
KR102398534B1 (ko) | 2020-11-05 | 2022-05-13 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 bnip3l 바이오마커 |
KR102398533B1 (ko) | 2020-11-05 | 2022-05-13 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 뇌척수액 마이토파지 마커 |
KR102470789B1 (ko) | 2020-11-05 | 2022-11-25 | 한림대학교 산학협력단 | 지연성 뇌허혈 진단을 위한 pink1 바이오마커 |
CN113462744B (zh) * | 2021-05-24 | 2023-06-23 | 中国药科大学 | N-乙酰葡萄糖胺作为标志物在制备诊断缺血性脑中风试剂中的应用 |
KR20230022141A (ko) | 2021-08-06 | 2023-02-14 | 에이치앤비지노믹스 주식회사 | 지능형 오믹스 기반 개인별 맞춤형 복잡질환 발병 위험도 정보 제공 방법 및 장치 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
CA2301634A1 (en) * | 1997-07-15 | 1999-01-28 | Pradeep Ghosh | Determining alcohol intake using sialic acid/apo j |
US6197599B1 (en) | 1998-07-30 | 2001-03-06 | Guorong Chin | Method to detect proteins |
EP1746902A4 (en) * | 2004-05-05 | 2007-06-13 | Univ Northeastern | MULTILEKTIN AFFINICHROMATOGRAPHY AND USE THEREOF |
WO2011007764A1 (ja) * | 2009-07-14 | 2011-01-20 | 独立行政法人産業技術総合研究所 | 肝疾患病態指標糖鎖マーカー |
ES2364169B1 (es) | 2010-02-09 | 2012-07-10 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Titular al 50%) | Uso de las isoformas de apo j como biomarcadores de lesión tisular. |
EP2400304A1 (en) * | 2010-06-22 | 2011-12-28 | Centro de Investigación Cooperativa En Biomateriales ( CIC biomaGUNE) | Method for the characterization of intermolecular interactions |
JP2012107932A (ja) | 2010-11-16 | 2012-06-07 | Mitsubishi Chemicals Corp | Clusterin蛋白質による脳梗塞の検査方法 |
DK3289363T3 (da) | 2015-04-30 | 2022-02-28 | Idexx Lab Inc | Specifik påvisning af clusterin isoformer |
CN107957498A (zh) * | 2016-10-18 | 2018-04-24 | 厦门德馨尚品医疗科技有限公司 | 一种含有载脂蛋白j的试剂盒及其在临床诊断中的应用 |
-
2016
- 2016-04-12 EP EP16382167.1A patent/EP3232200A1/en not_active Withdrawn
-
2017
- 2017-04-12 KR KR1020187032609A patent/KR102344344B1/ko active IP Right Grant
- 2017-04-12 RU RU2018139780A patent/RU2750035C2/ru active
- 2017-04-12 EP EP17717159.2A patent/EP3443353B1/en active Active
- 2017-04-12 AU AU2017251355A patent/AU2017251355A1/en not_active Abandoned
- 2017-04-12 US US16/092,703 patent/US11486884B2/en active Active
- 2017-04-12 JP JP2018554391A patent/JP7075894B2/ja active Active
- 2017-04-12 SG SG11201808820QA patent/SG11201808820QA/en unknown
- 2017-04-12 BR BR112018070971A patent/BR112018070971A2/pt not_active Application Discontinuation
- 2017-04-12 MX MX2018012580A patent/MX2018012580A/es unknown
- 2017-04-12 CN CN201780029342.8A patent/CN109154620B/zh active Active
- 2017-04-12 WO PCT/EP2017/058768 patent/WO2017178521A1/en active Application Filing
- 2017-04-12 CA CA3020666A patent/CA3020666A1/en active Pending
- 2017-04-12 MA MA044658A patent/MA44658A/fr unknown
-
2018
- 2018-10-09 IL IL262245A patent/IL262245B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA3020666A1 (en) | 2017-10-19 |
SG11201808820QA (en) | 2018-11-29 |
IL262245A (en) | 2018-11-29 |
AU2017251355A1 (en) | 2018-11-08 |
US20190128900A1 (en) | 2019-05-02 |
JP7075894B2 (ja) | 2022-05-26 |
EP3232200A1 (en) | 2017-10-18 |
IL262245B (en) | 2021-03-25 |
KR20190008216A (ko) | 2019-01-23 |
JP2019516966A (ja) | 2019-06-20 |
RU2750035C2 (ru) | 2021-06-21 |
EP3443353B1 (en) | 2024-03-13 |
CN109154620A (zh) | 2019-01-04 |
US11486884B2 (en) | 2022-11-01 |
BR112018070971A2 (pt) | 2019-01-29 |
MA44658A (fr) | 2019-02-20 |
EP3443353A1 (en) | 2019-02-20 |
CN109154620B (zh) | 2022-03-08 |
KR102344344B1 (ko) | 2021-12-28 |
WO2017178521A1 (en) | 2017-10-19 |
RU2018139780A (ru) | 2020-05-12 |
RU2018139780A3 (es) | 2020-07-24 |
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