IN2012DN06442A - - Google Patents

Info

Publication number
IN2012DN06442A
IN2012DN06442A IN6442DEN2012A IN2012DN06442A IN 2012DN06442 A IN2012DN06442 A IN 2012DN06442A IN 6442DEN2012 A IN6442DEN2012 A IN 6442DEN2012A IN 2012DN06442 A IN2012DN06442 A IN 2012DN06442A
Authority
IN
India
Prior art keywords
transformation
threonine
attenuated
reducing
modified strains
Prior art date
Application number
Other languages
English (en)
Inventor
Cédric Boisart
Corre Gwénaëlle Bestel
Guillaume Barbier
Rainer Figge
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of IN2012DN06442A publication Critical patent/IN2012DN06442A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y201/00—Transferases transferring one-carbon groups (2.1)
    • C12Y201/02—Hydroxymethyl-, formyl- and related transferases (2.1.2)
    • C12Y201/02001—Glycine hydroxymethyltransferase (2.1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/01—Ammonia-lyases (4.3.1)
    • C12Y403/01019—Threonine ammonia-lyase (4.3.1.19)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
IN6442DEN2012 2009-12-30 2010-12-29 IN2012DN06442A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29097509P 2009-12-30 2009-12-30
EP09306349 2009-12-30
PCT/EP2010/070858 WO2011080301A2 (en) 2009-12-30 2010-12-29 Strains and method for the production of methionine

Publications (1)

Publication Number Publication Date
IN2012DN06442A true IN2012DN06442A (ja) 2015-10-09

Family

ID=42562397

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6442DEN2012 IN2012DN06442A (ja) 2009-12-30 2010-12-29

Country Status (11)

Country Link
US (1) US9382561B2 (ja)
EP (1) EP2519637A2 (ja)
JP (1) JP5922036B2 (ja)
KR (1) KR101915819B1 (ja)
CN (1) CN102782137B (ja)
AR (1) AR079821A1 (ja)
BR (1) BR112012016908B1 (ja)
IN (1) IN2012DN06442A (ja)
MX (1) MX2012007717A (ja)
MY (1) MY172018A (ja)
WO (1) WO2011080301A2 (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012016908B1 (pt) * 2009-12-30 2020-03-31 Evonik Degussa Gmbh Linhagens e métodos para a produção de metionina
CN103981206B (zh) * 2014-06-06 2016-03-02 中国科学院天津工业生物技术研究所 一种筛选高产苏氨酸菌株的方法
KR20170044740A (ko) 2014-09-01 2017-04-25 메타볼릭 익스플로러 메티오닌 유출이 개선된 발효에 의한 메티오닌 생산을 위한 방법 및 미생물
CN104372035B (zh) * 2014-10-17 2017-10-31 湖南宝利士生物技术有限公司 合成高纯2‑酮酸盐的方法
CN104313071B (zh) * 2014-10-17 2018-04-13 湖南宝利士生物技术有限公司 高纯L‑α‑氨基酸的生物合成方法
EP3839053A3 (en) * 2015-01-27 2021-10-27 CysBio ApS Genetically modified microorganisms having improved tolerance towards l-serine
US20180223319A1 (en) 2015-08-07 2018-08-09 Evonik Degussa Gmbh Protein thiocarboxylate-dependent l-methionine production by fermentation
WO2017089077A1 (en) 2015-11-27 2017-06-01 Evonik Degussa Gmbh Method for producing l-methionine
EP3296404A1 (en) 2016-09-15 2018-03-21 Evonik Degussa GmbH Modified microorganism for production of methionine
CA3061731A1 (en) 2017-05-19 2018-11-22 Zymergen Inc. Genomic engineering of biosynthetic pathways leading to increased nadph
CN109402098B (zh) * 2018-11-06 2021-09-17 王喆明 苏氨酸醛缩酶、突变体及其在制备取代苯丝氨酸衍生物中的应用
US20200393381A1 (en) * 2019-06-12 2020-12-17 Henkel IP & Holding GmbH Method And System For Determining The Presence Of An Odorous Material On A Fabric
CN112779200B (zh) * 2021-01-12 2022-07-08 浙江工业大学 高产l-甲硫氨酸的基因工程菌及其构建与应用
WO2024096123A1 (ja) * 2022-11-04 2024-05-10 株式会社バイオパレット 遺伝子が改変された微生物およびその生産方法
WO2024149616A1 (en) 2023-01-09 2024-07-18 Evonik Operations Gmbh Fermentative production guanidinoacetic acid (gaa) from serine using a microorganism having an enhanced l-serine hydroxymethyltransferase activity
WO2024149617A1 (en) 2023-01-09 2024-07-18 Evonik Operations Gmbh Fermentative production guanidinoacetic acid (gaa) from serine by attenuating l serine ammonia lyase activity in microorganisms
CN118360227A (zh) * 2024-05-08 2024-07-19 杭州精构生物科技有限责任公司 一种发酵生产l-高丝氨酸的工程菌及其构建方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000157267A (ja) 1998-11-24 2000-06-13 Ajinomoto Co Inc 変異型ｍｅｔＪ遺伝子及びＬ−メチオニンの製造法
JPWO2002097086A1 (ja) * 2001-05-29 2005-04-07 協和醗酵工業株式会社 工業的生産に有用な微生物
DE10305774A1 (de) * 2003-02-06 2004-08-26 Consortium für elektrochemische Industrie GmbH Verfahren zur fermentativen Herstellung von L-Methionin
JP2006517796A (ja) 2003-02-18 2006-08-03 メタボリック エクスプローラー 代謝経路の生成または改変を可能とする進化した微生物の生産方法
DE10311399A1 (de) 2003-03-13 2004-09-23 Forschungszentrum Jülich GmbH Nukleotidsequenzen coryneformer Bakterien codierend für am L-Serinstoffwechsel beteiligte Proteine sowie Verfahren zur mikrobiellen Herstellung von L-Serin
WO2005111202A1 (en) 2004-05-12 2005-11-24 Metabolic Explorer Recombinant enzyme with altered feedback sensitivity
NO331033B1 (no) * 2005-07-07 2011-09-19 I P Huse As Anordning for transport av kjetting.
JP2009504172A (ja) 2005-08-18 2009-02-05 ビーエーエスエフ ソシエタス・ヨーロピア 向上したメチオニン合成効率を有する微生物
PL1969130T3 (pl) * 2006-01-04 2014-08-29 Evonik Degussa Gmbh Sposób wytwarzania metioniny i jej prekursorów lub sukcynylo homoseryny przy zastosowaniu mikroorganizmów
KR100905381B1 (ko) * 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
CN101849016A (zh) * 2007-02-19 2010-09-29 羸创德固赛有限责任公司 具有甲酰基-thf-合成酶和/或甘氨酸切割活性的棒状杆菌
KR100858913B1 (ko) * 2007-03-09 2008-09-17 한국과학기술원 부위특이적 변이에 의해 제조된 고수율의 ｌ－쓰레오닌생산균주 및 이를 이용한 ｌ－쓰레오닌의 제조방법
WO2009043372A1 (en) 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
WO2010020290A1 (en) 2008-08-22 2010-02-25 Metabolic Explorer Producing methionine without n-acetyl methionine
BR112012016908B1 (pt) 2009-12-30 2020-03-31 Evonik Degussa Gmbh Linhagens e métodos para a produção de metionina

Also Published As

Publication number Publication date
KR20120114325A (ko) 2012-10-16
KR101915819B1 (ko) 2018-11-06
WO2011080301A2 (en) 2011-07-07
CN102782137A (zh) 2012-11-14
JP5922036B2 (ja) 2016-05-24
JP2013516162A (ja) 2013-05-13
MY172018A (en) 2019-11-12
WO2011080301A3 (en) 2012-04-12
MX2012007717A (es) 2012-07-25
CN102782137B (zh) 2016-01-06
US9382561B2 (en) 2016-07-05
EP2519637A2 (en) 2012-11-07
BR112012016908B1 (pt) 2020-03-31
US20120288904A1 (en) 2012-11-15
AR079821A1 (es) 2012-02-22
BR112012016908A2 (pt) 2015-09-15

Similar Documents

Publication Publication Date Title
IN2012DN06442A (ja)
MX2013004495A (es) Microorganismo que produce o-fosfoserina y metodo para producir l-cisteina o derivados de la misma a partir de o-fosfoserina usando los mismos.
EP3027758A4 (en) Process for the enzymatic conversion of lignocellulosic biomass
IN2012DN03191A (ja)
IL221001A (en) An aqueous adhesive and a process for its manufacture
EP2589678A4 (en) High-strength steel sheet with excellent processability and process for producing same
MY169317A (en) Methods for converting lignocellulosic material to useful products
EP2433311A4 (en) METHOD FOR IMPROVED PRODUCTION OF PHOTOVOLTAIC PRODUCTS
HK1161332A1 (en) Bushing, piece with bushing, or method of producing
EP2462088A4 (en) PROCESS FOR THE PRODUCTION OF METHANE
PL2917359T3 (pl) Sposób enzymatycznej hydrolizy materiału lignocelulozowego z zastosowaniem tlenu
WO2012053794A3 (en) Microorganism producing o-phosphoserine and method of producing l-cysteine or derivatives thereof from o-phosphoserine using the same
EP2660213A4 (en) NON-ALKALIC GLASS AND METHOD FOR PRODUCING THE NON-ALKALINE GLASS
MX2011008275A (es) Plantas que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas.
EP2515169A4 (en) FOTOMASKENROHLING AND METHOD FOR PRODUCING A PHOTOMASK
IN2014DN03464A (ja)
ZA201107418B (en) Method for the production of hydrogen peroxide
TW201129620A (en) New formaldehyde scavengers
MY158910A (en) Surface modified silicic acid semi-gels
MX2011012623A (es) Construcciones de casb7439.
MX339772B (es) Metodo y composicion para producir azucar clarificada.
PH12015500737A1 (en) Recombinant microorganisms for producing organic acids
MX344498B (es) Procedimiento mejorado para preparar inhibidor de dipeptidil peptidasa-iv e intermediario.
MX2012010443A (es) Proceso para la preparacion de 1-alquiltetrazoles 5-sustituidos.
PL2513291T3 (pl) Nowe szczepy drożdży do wytwarzania alkoholu