IN187140B - - Google Patents

Info

Publication number
IN187140B
IN187140B IN1723CA1998A IN187140B IN 187140 B IN187140 B IN 187140B IN 1723CA1998 A IN1723CA1998 A IN 1723CA1998A IN 187140 B IN187140 B IN 187140B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Yasuyoshi Ueda
Akira Matsumoto
Hajime Manabe
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of IN187140B publication Critical patent/IN187140B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38Separation; Purification; Stabilisation; Use of additives
    • C07C227/40Separation; Purification
    • C07C227/42Crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Catalysts (AREA)
IN1723CA1998 1996-05-10 1998-09-24 IN187140B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11654596A JP3792777B2 (ja) 1996-05-10 1996-05-10 1−アルコキシカルボニル−3−フェニルプロピル誘導体の製造方法

Publications (1)

Publication Number Publication Date
IN187140B true IN187140B (es) 2002-02-09

Family

ID=14689775

Family Applications (2)

Application Number Title Priority Date Filing Date
IN838CA1997 IN183558B (es) 1996-05-10 1997-05-09
IN1723CA1998 IN187140B (es) 1996-05-10 1998-09-24

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IN838CA1997 IN183558B (es) 1996-05-10 1997-05-09

Country Status (13)

Country Link
US (1) US6118010A (es)
EP (2) EP1679303B1 (es)
JP (1) JP3792777B2 (es)
KR (1) KR100382633B1 (es)
CN (1) CN1159286C (es)
AT (1) ATE481378T1 (es)
CA (1) CA2254972C (es)
DE (2) DE69735667T2 (es)
ES (2) ES2353151T3 (es)
HU (1) HU227430B1 (es)
IN (2) IN183558B (es)
SI (1) SI9720039B (es)
WO (1) WO1997043246A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2277446T3 (es) * 1998-09-22 2007-07-01 Kaneka Corporation Proceso para la preparacion de n2-(1(s)-carboxi-3-fenilpropil)-l-lisil-l-prolina.
WO2001079176A1 (en) * 2000-04-18 2001-10-25 Scinopharm Singapore Pte Ltd Process for preparation of 3-[(1'-(alkoxycarbonyl)-3'-phenylpropyl)amino]-2-oxo-[1]-benzazepine and its derivatives
AR033048A1 (es) 2001-03-19 2003-12-03 Kaneka Corp Metodo para la purificacion de la n-(1(s)-etoxicarbonil-3-fenilpropil) -l-alanina
JP2003026644A (ja) * 2001-07-11 2003-01-29 Kanegafuchi Chem Ind Co Ltd N2−(1(s)−エトキシカルボニル−3−フェニルプロピル)−n6−トリフルオロアセチル−l−リジンの精製方法
SI21101A (sl) * 2001-11-26 2003-06-30 LEK farmacevtska dru�ba d.d. Koncentriranje vodnih frakcij lisinoprila z reverzno osmozo
EP1513868B1 (en) * 2002-06-19 2006-08-09 EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. Process for the production of lisinopril
JP4744979B2 (ja) * 2005-08-24 2011-08-10 独立行政法人理化学研究所 ゼオライトを用いたタンパク質結晶化方法
PT2118123E (pt) 2007-01-31 2016-02-10 Harvard College Péptidos de p53 estabilizados e suas utilizações
WO2008121767A2 (en) 2007-03-28 2008-10-09 President And Fellows Of Harvard College Stitched polypeptides
CN101239923B (zh) * 2007-12-31 2010-09-15 浙江工业大学 (s,s)n-(1-乙氧羰基-3-苯丙基)-l-氨基酸衍生物的制备方法与精制方法
RU2582678C2 (ru) 2010-08-13 2016-04-27 Эйлерон Терапьютикс, Инк. Пептидомиметические макроциклы
CN101973904B (zh) * 2010-09-28 2014-01-01 雅本化学股份有限公司 一种具有高光学纯度的n2-[1-(s)-乙氧羰基-3-苯丙基]-n6-三氟乙酰基-l-赖氨酸的制备方法
TWI643868B (zh) 2011-10-18 2018-12-11 艾利倫治療公司 擬肽巨環化合物
JP6450191B2 (ja) 2012-02-15 2019-01-09 エイルロン セラピューティクス,インコーポレイテッド ペプチドミメティック大環状化合物
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
CN105294827A (zh) * 2014-07-21 2016-02-03 常州制药厂有限公司 一种马来酸依那普利的制备方法
KR102570210B1 (ko) 2014-09-24 2023-08-23 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 제제
KR20170058424A (ko) 2014-09-24 2017-05-26 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 용도
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. ペプチド模倣大環状分子およびその使用
CN106220545B (zh) * 2016-07-21 2019-08-13 成都摩尔生物医药有限公司 一种acei药物环己基杂质的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1327787A3 (ru) * 1981-11-05 1987-07-30 Хехст Аг (Фирма) Способ получени цис,эндо-2-азабицикло-/3,3,0/-октан-3-карбоновых кислот или их кислотно-аддитивных солей
DE3246503A1 (de) * 1982-12-16 1984-06-20 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(5.3.0)-decan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
EP0190687B1 (en) * 1985-02-04 1988-10-05 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing ethyl-alpha-(1-carboxyethyl)-amino-gamma-oxo-gamma-phenylbutyrate
JPH01104034A (ja) * 1986-03-27 1989-04-21 Kanegafuchi Chem Ind Co Ltd N↑2−(1−カルボキシ−3−フエニルプロピル)−l−リジン誘導体の製造法
EP0239062B1 (en) * 1986-03-27 1991-05-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha N2-(1-carboxy-3-oxo-3-phenylpropyl)-l-lysine compounds and their derivatives
JPS62239062A (ja) * 1986-04-11 1987-10-19 Matsushita Electric Ind Co Ltd 交差コイル式メ−タの駆動回路
JPH03115254A (ja) * 1990-09-12 1991-05-16 Kanegafuchi Chem Ind Co Ltd α―(1―カルボキシエチル)アミノ―γ―フエニル酪酸エチルの製造法
JPH06336495A (ja) * 1993-05-28 1994-12-06 Kyowa Hakko Kogyo Co Ltd L−アラニル−l−プロリン誘導体の製造法

Also Published As

Publication number Publication date
EP0903337B1 (en) 2006-04-12
DE69739998D1 (de) 2010-10-28
CN1159286C (zh) 2004-07-28
DE69735667D1 (de) 2006-05-24
ES2353151T3 (es) 2011-02-25
CN1218454A (zh) 1999-06-02
EP1679303A1 (en) 2006-07-12
EP1679303B1 (en) 2010-09-15
DE69735667T2 (de) 2007-04-26
EP0903337A4 (en) 2001-02-28
IN183558B (es) 2000-02-12
CA2254972C (en) 2005-08-02
WO1997043246A1 (en) 1997-11-20
SI9720039A (sl) 1999-08-31
JP3792777B2 (ja) 2006-07-05
US6118010A (en) 2000-09-12
HU227430B1 (hu) 2011-06-28
EP0903337A1 (en) 1999-03-24
HUP9903214A3 (en) 2002-12-28
SI9720039B (sl) 2002-02-28
KR20000010840A (ko) 2000-02-25
ATE481378T1 (de) 2010-10-15
KR100382633B1 (ko) 2003-07-12
ES2257775T3 (es) 2006-08-01
JPH09301938A (ja) 1997-11-25
CA2254972A1 (en) 1997-11-20

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