IL95143A - Preparation of a benzopyran that lowers blood pressure and intermediate - Google Patents
Preparation of a benzopyran that lowers blood pressure and intermediateInfo
- Publication number
- IL95143A IL95143A IL9514390A IL9514390A IL95143A IL 95143 A IL95143 A IL 95143A IL 9514390 A IL9514390 A IL 9514390A IL 9514390 A IL9514390 A IL 9514390A IL 95143 A IL95143 A IL 95143A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- hours
- compound
- cyano
- alkali
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU893699A HU207861B (en) | 1989-07-21 | 1989-07-21 | Process for producing benzopirane derivative of blood pressure lowering activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL95143A0 IL95143A0 (en) | 1991-06-10 |
| IL95143A true IL95143A (en) | 1996-10-31 |
Family
ID=10965123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9514390A IL95143A (en) | 1989-07-21 | 1990-07-20 | Preparation of a benzopyran that lowers blood pressure and intermediate |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5145985A (fr) |
| EP (1) | EP0409651B1 (fr) |
| JP (1) | JPH0358988A (fr) |
| CZ (1) | CZ283969B6 (fr) |
| DE (1) | DE69019080T2 (fr) |
| ES (1) | ES2072982T3 (fr) |
| HU (1) | HU207861B (fr) |
| IL (1) | IL95143A (fr) |
| PL (1) | PL286145A1 (fr) |
| RU (2) | RU2036196C1 (fr) |
| SK (1) | SK362990A3 (fr) |
| YU (1) | YU139090A (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837702A (en) * | 1993-10-07 | 1998-11-17 | Bristol-Myers Squibb Co. | 4-arylamino-benzopyran and related compounds |
| US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
| US5629429A (en) * | 1995-06-07 | 1997-05-13 | Bristol-Myers Squibb Company | Process for preparing 4-arylamino-benzopyran and related compounds |
| US5612370A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phenylglycine and phenylalaninen amido benzopyran derivatives |
| US5612323A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phosphinic ester substituted benzopyran derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4391815A (en) * | 1976-04-02 | 1983-07-05 | Beecham Group Limited | Cyanobenzano[b]pyrans |
| DE2851207A1 (de) * | 1977-12-06 | 1979-06-07 | Garcia De Lama Javier | Verfahren zur herstellung substituierter 4h-pyran-4-one |
| DE3274350D1 (en) * | 1981-09-25 | 1987-01-08 | Beecham Group Plc | Pharmaceutically active benzopyran compounds |
| HU194214B (en) * | 1983-02-15 | 1988-01-28 | Alkaloida Vegyeszeti Gyar | Process for producing 7-alkoxy-2h-chromene derivatives and insecticide and nematocide compositions containing them as active components |
| GB8308062D0 (en) * | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
-
1989
- 1989-07-21 HU HU893699A patent/HU207861B/hu not_active IP Right Cessation
-
1990
- 1990-06-25 US US07/543,142 patent/US5145985A/en not_active Expired - Fee Related
- 1990-07-17 YU YU139090A patent/YU139090A/sh unknown
- 1990-07-20 JP JP2193788A patent/JPH0358988A/ja active Pending
- 1990-07-20 CZ CS903629A patent/CZ283969B6/cs unknown
- 1990-07-20 SK SK3629-90A patent/SK362990A3/sk unknown
- 1990-07-20 ES ES90307975T patent/ES2072982T3/es not_active Expired - Lifetime
- 1990-07-20 EP EP90307975A patent/EP0409651B1/fr not_active Expired - Lifetime
- 1990-07-20 IL IL9514390A patent/IL95143A/en not_active IP Right Cessation
- 1990-07-20 RU SU904830502A patent/RU2036196C1/ru active
- 1990-07-20 PL PL28614590A patent/PL286145A1/xx unknown
- 1990-07-20 DE DE69019080T patent/DE69019080T2/de not_active Expired - Fee Related
-
1992
- 1992-02-19 RU SU925010854A patent/RU2041223C1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2036196C1 (ru) | 1995-05-27 |
| DE69019080D1 (de) | 1995-06-08 |
| HUT58321A (en) | 1992-02-28 |
| EP0409651A1 (fr) | 1991-01-23 |
| PL286145A1 (en) | 1991-07-15 |
| EP0409651B1 (fr) | 1995-05-03 |
| CZ283969B6 (cs) | 1998-07-15 |
| JPH0358988A (ja) | 1991-03-14 |
| SK278873B6 (sk) | 1998-04-08 |
| RU2041223C1 (ru) | 1995-08-09 |
| DE69019080T2 (de) | 1995-11-02 |
| ES2072982T3 (es) | 1995-08-01 |
| YU139090A (sh) | 1993-05-28 |
| US5145985A (en) | 1992-09-08 |
| SK362990A3 (en) | 1998-04-08 |
| CZ362990A3 (cs) | 1998-03-18 |
| HU207861B (en) | 1993-06-28 |
| IL95143A0 (en) | 1991-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH | Patent void |