IL93670A - Sodium N-acetylneuramine trihydrate - Google Patents
Sodium N-acetylneuramine trihydrateInfo
- Publication number
- IL93670A IL93670A IL9367090A IL9367090A IL93670A IL 93670 A IL93670 A IL 93670A IL 9367090 A IL9367090 A IL 9367090A IL 9367090 A IL9367090 A IL 9367090A IL 93670 A IL93670 A IL 93670A
- Authority
- IL
- Israel
- Prior art keywords
- sodium
- acetylneuraminate
- trihydrate
- solution
- ethanol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1055388A JP2745059B2 (ja) | 1989-03-08 | 1989-03-08 | Ｎ―アセチルノイラミン酸ナトリウム・三水和物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL93670A true IL93670A (en) | 1994-08-26 |
Family
ID=12997127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9367090A IL93670A (en) | 1989-03-08 | 1990-03-06 | Sodium N-acetylneuramine trihydrate |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5231177A (fi) |
| EP (1) | EP0386721B1 (fi) |
| JP (1) | JP2745059B2 (fi) |
| KR (1) | KR0128369B1 (fi) |
| CN (1) | CN1026982C (fi) |
| AT (1) | ATE118217T1 (fi) |
| AU (1) | AU621203B2 (fi) |
| CA (1) | CA2011468C (fi) |
| DE (1) | DE69016683T2 (fi) |
| DK (1) | DK0386721T3 (fi) |
| ES (1) | ES2067580T3 (fi) |
| FI (1) | FI95267C (fi) |
| HU (1) | HU203247B (fi) |
| IL (1) | IL93670A (fi) |
| NO (1) | NO173701C (fi) |
| NZ (1) | NZ232806A (fi) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI291462B (en) | 2000-04-25 | 2007-12-21 | Daiichi Sankyo Co Ltd | Hydrate crystal of neuraminic acid compound |
| AU2008272854B2 (en) * | 2007-07-03 | 2014-03-13 | Children's Hospital & Research Center At Oakland | Inhibitors of polysialic acid de-N-acetylase and methods for using the same |
| JP5523313B2 (ja) * | 2007-07-03 | 2014-06-18 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用 |
| EP2173759A4 (en) | 2007-07-03 | 2014-01-29 | Childrens Hosp & Res Ct Oak | OLIGOSIALIC ACID DERIVATIVES, METHODS OF MANUFACTURE AND IMMUNOLOGICAL USES |
| CA2859296C (en) * | 2011-12-16 | 2016-10-11 | Daiichi Sankyo Company, Limited | Method for manufacturing neuraminic acid derivatives |
| US10005808B2 (en) | 2014-07-30 | 2018-06-26 | Kyowa Hakko Bio Co., Ltd. | Crystal of alkali metal N-acetylneuraminate anhydrate, and process for producing same |
| CN107207552B (zh) * | 2015-01-28 | 2021-03-26 | 协和发酵生化株式会社 | N-乙酰神经氨酸铵盐无水物的晶体及其制造方法 |
| CN109232677B (zh) * | 2018-10-18 | 2021-12-28 | 中国科学院合肥物质科学研究院 | 一种使n-乙酰神经氨酸水合物转化为n-乙酰神经氨酸的方法 |
| CN109265497B (zh) * | 2018-10-18 | 2022-04-19 | 武汉中科光谷绿色生物技术有限公司 | 一种利用有机溶剂转化n-乙酰神经氨酸水合物制备n-乙酰神经氨酸的方法 |
| CN109180749B (zh) * | 2018-10-18 | 2022-04-22 | 中国科学院合肥物质科学研究院 | 一种利用过饱和结晶法制备高纯度n-乙酰神经氨酸水合物的方法 |
| CN110606863B (zh) * | 2019-10-08 | 2023-05-30 | 中国科学院合肥物质科学研究院 | 一种n-乙酰神经氨酸二水合物的制备方法 |
| CN110627849B (zh) * | 2019-10-15 | 2023-02-17 | 中国科学院合肥物质科学研究院 | 一种n-乙酰神经氨酸标准物质的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8002823A (nl) * | 1980-05-14 | 1981-12-16 | Amsterdam Chem Comb | Lactitolmonohydraat, alsmede werkwijze voor het bereiden van kristallijn lactitol. |
| JPS6053039B2 (ja) * | 1981-06-26 | 1985-11-22 | メクト株式会社 | Ｎ−アセチル／イラミン酸誘導体およびその製造方法 |
| AU582758B2 (en) * | 1984-06-28 | 1989-04-13 | Mect Corporation | Sialic acid derivatives, galactose derivatives and method for producing the same |
| JPS61103889A (ja) * | 1984-10-24 | 1986-05-22 | Hayashibara Biochem Lab Inc | 結晶エルロ−ス及びそれを含有する含蜜結晶並びにそれらの製造方法及び用途 |
| JPS6344590A (ja) * | 1986-08-12 | 1988-02-25 | Mect Corp | シアル酸誘導体の製造方法 |
| IT1223398B (it) * | 1987-12-01 | 1990-09-19 | Sirac Spa | Procedimento per la preparazione di lattulosio cristallino ad alta purezza |
| JPH01299294A (ja) * | 1988-05-24 | 1989-12-04 | Mect Corp | ４，８−アンハイドロ−ｎ−アセチルノイラミン酸誘導体 |
| EP0369369B1 (en) * | 1988-11-16 | 1994-01-26 | Nippon Kayaku Kabushiki Kaisha | Dihydrate crystals of etoposide-2-dimethylamino compound hydrochloride and a process for production thereof |
-
1989
- 1989-03-08 JP JP1055388A patent/JP2745059B2/ja not_active Expired - Fee Related
-
1990
- 1990-03-05 US US07/488,860 patent/US5231177A/en not_active Expired - Lifetime
- 1990-03-06 NZ NZ232806A patent/NZ232806A/xx unknown
- 1990-03-06 IL IL9367090A patent/IL93670A/en not_active IP Right Cessation
- 1990-03-07 ES ES90104335T patent/ES2067580T3/es not_active Expired - Lifetime
- 1990-03-07 AT AT90104335T patent/ATE118217T1/de not_active IP Right Cessation
- 1990-03-07 KR KR1019900002983A patent/KR0128369B1/ko not_active IP Right Cessation
- 1990-03-07 DK DK90104335.6T patent/DK0386721T3/da active
- 1990-03-07 FI FI901150A patent/FI95267C/fi not_active IP Right Cessation
- 1990-03-07 CA CA002011468A patent/CA2011468C/en not_active Expired - Fee Related
- 1990-03-07 NO NO901084A patent/NO173701C/no unknown
- 1990-03-07 AU AU50776/90A patent/AU621203B2/en not_active Ceased
- 1990-03-07 HU HU901346A patent/HU203247B/hu not_active IP Right Cessation
- 1990-03-07 EP EP90104335A patent/EP0386721B1/en not_active Expired - Lifetime
- 1990-03-07 DE DE69016683T patent/DE69016683T2/de not_active Expired - Fee Related
- 1990-03-08 CN CN90101959A patent/CN1026982C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU203247B (en) | 1991-06-28 |
| DK0386721T3 (da) | 1995-07-10 |
| KR0128369B1 (ko) | 1998-04-03 |
| JPH02235897A (ja) | 1990-09-18 |
| AU621203B2 (en) | 1992-03-05 |
| FI901150A0 (fi) | 1990-03-07 |
| US5231177A (en) | 1993-07-27 |
| NO173701B (no) | 1993-10-11 |
| JP2745059B2 (ja) | 1998-04-28 |
| NO901084D0 (no) | 1990-03-07 |
| NO173701C (no) | 1994-01-19 |
| FI95267C (fi) | 1996-01-10 |
| HUT53117A (en) | 1990-09-28 |
| CN1026982C (zh) | 1994-12-14 |
| CN1045584A (zh) | 1990-09-26 |
| AU5077690A (en) | 1990-09-20 |
| EP0386721B1 (en) | 1995-02-08 |
| DE69016683T2 (de) | 1995-06-08 |
| CA2011468C (en) | 1996-09-10 |
| NZ232806A (en) | 1991-10-25 |
| ATE118217T1 (de) | 1995-02-15 |
| FI95267B (fi) | 1995-09-29 |
| DE69016683D1 (de) | 1995-03-23 |
| CA2011468A1 (en) | 1990-09-08 |
| HU901346D0 (en) | 1990-05-28 |
| EP0386721A1 (en) | 1990-09-12 |
| NO901084L (no) | 1990-09-10 |
| KR900014419A (ko) | 1990-10-23 |
| ES2067580T3 (es) | 1995-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH | Patent void |