DK0386721T3 - Natrium-N-acetylneuraminat-trihydrat og fremgangsmåde til fremstilling deraf - Google Patents

Natrium-N-acetylneuraminat-trihydrat og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0386721T3
DK0386721T3 DK90104335.6T DK90104335T DK0386721T3 DK 0386721 T3 DK0386721 T3 DK 0386721T3 DK 90104335 T DK90104335 T DK 90104335T DK 0386721 T3 DK0386721 T3 DK 0386721T3
Authority
DK
Denmark
Prior art keywords
sodium
acetylneuraminate
trihydrate
preparation
water
Prior art date
Application number
DK90104335.6T
Other languages
English (en)
Inventor
Kinichi Saito
Hideo Mizu
Naokazu Sugiyama
Shikoh Minagawa
Motoaki Goto
Kenji Abiko
Original Assignee
Kanto Ishi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanto Ishi Pharma Co Ltd filed Critical Kanto Ishi Pharma Co Ltd
Application granted granted Critical
Publication of DK0386721T3 publication Critical patent/DK0386721T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK90104335.6T 1989-03-08 1990-03-07 Natrium-N-acetylneuraminat-trihydrat og fremgangsmåde til fremstilling deraf DK0386721T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1055388A JP2745059B2 (ja) 1989-03-08 1989-03-08 Ｎ―アセチルノイラミン酸ナトリウム・三水和物

Publications (1)

Publication Number Publication Date
DK0386721T3 true DK0386721T3 (da) 1995-07-10

Family

ID=12997127

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90104335.6T DK0386721T3 (da) 1989-03-08 1990-03-07 Natrium-N-acetylneuraminat-trihydrat og fremgangsmåde til fremstilling deraf

Country Status (16)

Country Link
US (1) US5231177A (da)
EP (1) EP0386721B1 (da)
JP (1) JP2745059B2 (da)
KR (1) KR0128369B1 (da)
CN (1) CN1026982C (da)
AT (1) ATE118217T1 (da)
AU (1) AU621203B2 (da)
CA (1) CA2011468C (da)
DE (1) DE69016683T2 (da)
DK (1) DK0386721T3 (da)
ES (1) ES2067580T3 (da)
FI (1) FI95267C (da)
HU (1) HU203247B (da)
IL (1) IL93670A (da)
NO (1) NO173701C (da)
NZ (1) NZ232806A (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI291462B (en) 2000-04-25 2007-12-21 Daiichi Sankyo Co Ltd Hydrate crystal of neuraminic acid compound
AU2008272854B2 (en) * 2007-07-03 2014-03-13 Children's Hospital & Research Center At Oakland Inhibitors of polysialic acid de-N-acetylase and methods for using the same
JP5523313B2 (ja) * 2007-07-03 2014-06-18 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用
EP2173759A4 (en) 2007-07-03 2014-01-29 Childrens Hosp & Res Ct Oak OLIGOSIALIC ACID DERIVATIVES, METHODS OF MANUFACTURE AND IMMUNOLOGICAL USES
CA2859296C (en) * 2011-12-16 2016-10-11 Daiichi Sankyo Company, Limited Method for manufacturing neuraminic acid derivatives
US10005808B2 (en) 2014-07-30 2018-06-26 Kyowa Hakko Bio Co., Ltd. Crystal of alkali metal N-acetylneuraminate anhydrate, and process for producing same
CN107207552B (zh) * 2015-01-28 2021-03-26 协和发酵生化株式会社 N-乙酰神经氨酸铵盐无水物的晶体及其制造方法
CN109232677B (zh) * 2018-10-18 2021-12-28 中国科学院合肥物质科学研究院 一种使n-乙酰神经氨酸水合物转化为n-乙酰神经氨酸的方法
CN109265497B (zh) * 2018-10-18 2022-04-19 武汉中科光谷绿色生物技术有限公司 一种利用有机溶剂转化n-乙酰神经氨酸水合物制备n-乙酰神经氨酸的方法
CN109180749B (zh) * 2018-10-18 2022-04-22 中国科学院合肥物质科学研究院 一种利用过饱和结晶法制备高纯度n-乙酰神经氨酸水合物的方法
CN110606863B (zh) * 2019-10-08 2023-05-30 中国科学院合肥物质科学研究院 一种n-乙酰神经氨酸二水合物的制备方法
CN110627849B (zh) * 2019-10-15 2023-02-17 中国科学院合肥物质科学研究院 一种n-乙酰神经氨酸标准物质的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8002823A (nl) * 1980-05-14 1981-12-16 Amsterdam Chem Comb Lactitolmonohydraat, alsmede werkwijze voor het bereiden van kristallijn lactitol.
JPS6053039B2 (ja) * 1981-06-26 1985-11-22 メクト株式会社 Ｎ−アセチル／イラミン酸誘導体およびその製造方法
AU582758B2 (en) * 1984-06-28 1989-04-13 Mect Corporation Sialic acid derivatives, galactose derivatives and method for producing the same
JPS61103889A (ja) * 1984-10-24 1986-05-22 Hayashibara Biochem Lab Inc 結晶エルロ−ス及びそれを含有する含蜜結晶並びにそれらの製造方法及び用途
JPS6344590A (ja) * 1986-08-12 1988-02-25 Mect Corp シアル酸誘導体の製造方法
IT1223398B (it) * 1987-12-01 1990-09-19 Sirac Spa Procedimento per la preparazione di lattulosio cristallino ad alta purezza
JPH01299294A (ja) * 1988-05-24 1989-12-04 Mect Corp ４，８−アンハイドロ−ｎ−アセチルノイラミン酸誘導体
EP0369369B1 (en) * 1988-11-16 1994-01-26 Nippon Kayaku Kabushiki Kaisha Dihydrate crystals of etoposide-2-dimethylamino compound hydrochloride and a process for production thereof

Also Published As

Publication number Publication date
HU203247B (en) 1991-06-28
KR0128369B1 (ko) 1998-04-03
JPH02235897A (ja) 1990-09-18
AU621203B2 (en) 1992-03-05
FI901150A0 (fi) 1990-03-07
US5231177A (en) 1993-07-27
NO173701B (no) 1993-10-11
IL93670A (en) 1994-08-26
JP2745059B2 (ja) 1998-04-28
NO901084D0 (no) 1990-03-07
NO173701C (no) 1994-01-19
FI95267C (fi) 1996-01-10
HUT53117A (en) 1990-09-28
CN1026982C (zh) 1994-12-14
CN1045584A (zh) 1990-09-26
AU5077690A (en) 1990-09-20
EP0386721B1 (en) 1995-02-08
DE69016683T2 (de) 1995-06-08
CA2011468C (en) 1996-09-10
NZ232806A (en) 1991-10-25
ATE118217T1 (de) 1995-02-15
FI95267B (fi) 1995-09-29
DE69016683D1 (de) 1995-03-23
CA2011468A1 (en) 1990-09-08
HU901346D0 (en) 1990-05-28
EP0386721A1 (en) 1990-09-12
NO901084L (no) 1990-09-10
KR900014419A (ko) 1990-10-23
ES2067580T3 (es) 1995-04-01

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