IL92962A - 1-Troaril-3-Noble-2-Oxindoles against thinning and pharmaceuticals containing them - Google Patents

1-Troaril-3-Noble-2-Oxindoles against thinning and pharmaceuticals containing them

Info

Publication number
IL92962A
IL92962A IL9296290A IL9296290A IL92962A IL 92962 A IL92962 A IL 92962A IL 9296290 A IL9296290 A IL 9296290A IL 9296290 A IL9296290 A IL 9296290A IL 92962 A IL92962 A IL 92962A
Authority
IL
Israel
Prior art keywords
thienyl
furyl
thiazolyl
formula
compound according
Prior art date
Application number
IL9296290A
Other languages
English (en)
Hebrew (he)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL92962A publication Critical patent/IL92962A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IL9296290A 1989-01-10 1990-01-03 1-Troaril-3-Noble-2-Oxindoles against thinning and pharmaceuticals containing them IL92962A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/000079 WO1990008145A1 (en) 1989-01-10 1989-01-10 Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles

Publications (1)

Publication Number Publication Date
IL92962A true IL92962A (en) 1995-01-24

Family

ID=22214772

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9296290A IL92962A (en) 1989-01-10 1990-01-03 1-Troaril-3-Noble-2-Oxindoles against thinning and pharmaceuticals containing them

Country Status (18)

Country Link
EP (1) EP0378358B1 (fi)
JP (1) JPH0692400B2 (fi)
KR (1) KR920006785B1 (fi)
AT (1) ATE96793T1 (fi)
AU (1) AU616336B2 (fi)
CA (1) CA2007655C (fi)
DE (1) DE69004272T2 (fi)
DK (1) DK0378358T3 (fi)
ES (1) ES2060007T3 (fi)
FI (1) FI92827C (fi)
HU (1) HU215112B (fi)
IE (1) IE62143B1 (fi)
IL (1) IL92962A (fi)
NO (1) NO179103C (fi)
NZ (1) NZ232039A (fi)
PT (1) PT92800B (fi)
WO (1) WO1990008145A1 (fi)
ZA (1) ZA90139B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2886541A1 (en) * 2013-12-19 2015-06-24 Sanofi Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases
CN108456205B (zh) * 2018-05-21 2021-06-04 深圳市众康动保科技有限公司 一种3,3二取代羟基吲哚化合物的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053613A (en) * 1975-09-17 1977-10-11 E. R. Squibb & Sons, Inc. 1,3,thiazolinyl and 1,3 thiazinyl substituted indolinones
ATE63543T1 (de) * 1984-02-07 1991-06-15 Pfizer 2-oxindolzwischenprodukte.
US4721712A (en) * 1984-06-12 1988-01-26 Pfizer Inc. 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents
IN163263B (fi) * 1984-02-07 1988-08-27 Pfizer
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
HU203350B (en) * 1984-08-24 1991-07-29 Pfizer Process for producing antiinflammatory tricyclic oxindole derivatives
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
US4752609A (en) * 1985-06-20 1988-06-21 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds

Also Published As

Publication number Publication date
CA2007655A1 (en) 1991-07-12
NO179103C (no) 1996-08-07
DE69004272T2 (de) 1994-02-24
AU4781690A (en) 1990-07-19
HU215112B (hu) 1998-12-28
FI92827C (fi) 1995-01-10
JPH02270868A (ja) 1990-11-05
KR900011762A (ko) 1990-08-02
ATE96793T1 (de) 1993-11-15
CA2007655C (en) 1996-10-22
ZA90139B (en) 1991-08-28
PT92800A (pt) 1990-07-31
HUT62292A (en) 1993-04-28
KR920006785B1 (ko) 1992-08-17
FI913324A0 (fi) 1991-07-09
IE900075L (en) 1990-07-10
AU616336B2 (en) 1991-10-24
NO912694D0 (no) 1991-07-09
IE62143B1 (en) 1994-12-14
NO179103B (no) 1996-04-29
DK0378358T3 (da) 1993-12-06
NZ232039A (en) 1991-07-26
ES2060007T3 (es) 1994-11-16
JPH0692400B2 (ja) 1994-11-16
NO912694L (no) 1991-07-09
PT92800B (pt) 1995-12-29
EP0378358A1 (en) 1990-07-18
DE69004272D1 (de) 1993-12-09
EP0378358B1 (en) 1993-11-03
WO1990008145A1 (en) 1990-07-26
FI92827B (fi) 1994-09-30

Similar Documents

Publication Publication Date Title
CA2014467C (en) 3-substituted-2-oxindole derivatives
US4180662A (en) Thiazine derivatives
Daidone et al. Synthesis and pharmacological study of ethyl 1-methyl-5-[2-substituted-4-oxo-3 (4H)-quinazolinyl]-1H-pyrazole-4-acetates
US5116854A (en) Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles
IE910022A1 (en) Azaoxindole derivatives
US5811432A (en) Azaoxindole derivatives
EP0181136B1 (en) Oxindole antiinflammatory agents
US4478842A (en) N-Substituted-2-pyridylindoles
KR880002010B1 (ko) 1-치환 2-피리딜 인돌, 그의 n-옥사이드 및 그의 염의 제조방법
IL92962A (en) 1-Troaril-3-Noble-2-Oxindoles against thinning and pharmaceuticals containing them
EP0378357B1 (en) Anti-inflammatory 1-heteroaryloxindole-3-carboxamides
KR870000289B1 (ko) 2-옥스인돌 유도체의 제조방법
JPH0753730B2 (ja) イミダゾピラゾール誘導体
JP2891367B2 (ja) 四環性化合物
JPS6159314B2 (fi)

Legal Events

Date Code Title Description
KB Patent renewed
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees