ZA90139B - Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles - Google Patents

Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles

Info

Publication number
ZA90139B
ZA90139B ZA90139A ZA90139A ZA90139B ZA 90139 B ZA90139 B ZA 90139B ZA 90139 A ZA90139 A ZA 90139A ZA 90139 A ZA90139 A ZA 90139A ZA 90139 B ZA90139 B ZA 90139B
Authority
ZA
South Africa
Prior art keywords
oxindoles
heteroaryl
acyl
alkyl
formula
Prior art date
Application number
ZA90139A
Other languages
English (en)
Inventor
Anthony Marfat
Marfat Anthony
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA90139B publication Critical patent/ZA90139B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
ZA90139A 1989-01-10 1990-01-09 Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles ZA90139B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/000079 WO1990008145A1 (en) 1989-01-10 1989-01-10 Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles

Publications (1)

Publication Number Publication Date
ZA90139B true ZA90139B (en) 1991-08-28

Family

ID=22214772

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA90139A ZA90139B (en) 1989-01-10 1990-01-09 Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles

Country Status (18)

Country Link
EP (1) EP0378358B1 (fi)
JP (1) JPH0692400B2 (fi)
KR (1) KR920006785B1 (fi)
AT (1) ATE96793T1 (fi)
AU (1) AU616336B2 (fi)
CA (1) CA2007655C (fi)
DE (1) DE69004272T2 (fi)
DK (1) DK0378358T3 (fi)
ES (1) ES2060007T3 (fi)
FI (1) FI92827C (fi)
HU (1) HU215112B (fi)
IE (1) IE62143B1 (fi)
IL (1) IL92962A (fi)
NO (1) NO179103C (fi)
NZ (1) NZ232039A (fi)
PT (1) PT92800B (fi)
WO (1) WO1990008145A1 (fi)
ZA (1) ZA90139B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2886541A1 (en) * 2013-12-19 2015-06-24 Sanofi Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases
CN108456205B (zh) * 2018-05-21 2021-06-04 深圳市众康动保科技有限公司 一种3,3二取代羟基吲哚化合物的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053613A (en) * 1975-09-17 1977-10-11 E. R. Squibb & Sons, Inc. 1,3,thiazolinyl and 1,3 thiazinyl substituted indolinones
ATE63543T1 (de) * 1984-02-07 1991-06-15 Pfizer 2-oxindolzwischenprodukte.
US4721712A (en) * 1984-06-12 1988-01-26 Pfizer Inc. 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents
IN163263B (fi) * 1984-02-07 1988-08-27 Pfizer
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
HU203350B (en) * 1984-08-24 1991-07-29 Pfizer Process for producing antiinflammatory tricyclic oxindole derivatives
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
US4752609A (en) * 1985-06-20 1988-06-21 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds

Also Published As

Publication number Publication date
CA2007655A1 (en) 1991-07-12
NO179103C (no) 1996-08-07
DE69004272T2 (de) 1994-02-24
AU4781690A (en) 1990-07-19
HU215112B (hu) 1998-12-28
FI92827C (fi) 1995-01-10
JPH02270868A (ja) 1990-11-05
KR900011762A (ko) 1990-08-02
ATE96793T1 (de) 1993-11-15
CA2007655C (en) 1996-10-22
PT92800A (pt) 1990-07-31
HUT62292A (en) 1993-04-28
KR920006785B1 (ko) 1992-08-17
FI913324A0 (fi) 1991-07-09
IL92962A (en) 1995-01-24
IE900075L (en) 1990-07-10
AU616336B2 (en) 1991-10-24
NO912694D0 (no) 1991-07-09
IE62143B1 (en) 1994-12-14
NO179103B (no) 1996-04-29
DK0378358T3 (da) 1993-12-06
NZ232039A (en) 1991-07-26
ES2060007T3 (es) 1994-11-16
JPH0692400B2 (ja) 1994-11-16
NO912694L (no) 1991-07-09
PT92800B (pt) 1995-12-29
EP0378358A1 (en) 1990-07-18
DE69004272D1 (de) 1993-12-09
EP0378358B1 (en) 1993-11-03
WO1990008145A1 (en) 1990-07-26
FI92827B (fi) 1994-09-30

Similar Documents

Publication Publication Date Title
MX9805291A (es) Derivados de feniltiazol con propiedades anti-virus de herpes.
CA2113561A1 (en) Phosphonic Diester Derivative
NO941698L (no) Collagenaseinhibitor
FI954994A (fi) 3-(het)aryylikarboksyylihappojohdannaiset, menetelmä ja välituotteet niiden valmistamiseksi
IL136359A (en) Dihydrobenzofuran substituted phthalazin-1-one derivatives and pharmaceutical compositions containing the same
IE900075L (en) Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles
AR020950A1 (es) Compuestos de 3-(fenil sustituido)-5-tienil-1,2,4-triazolo con actividad contra la mosca blanca
AU1192397A (en) Substituted thiazolines and their use for controlling animal pests
FI954993A0 (fi) 3-(het)aryylioksi(tio)karboksyylihappojohdannaiset, menetelmä ja välituotteet niiden valmistamiseksi
AU4781790A (en) Anti-inflammatory 1-heteroaryloxindole-3-carboxamides
TW350843B (en) 2-(4-pyrazolyloxy-pyrimidin-5-yl) acetic acid derivatives
DE60102695D1 (de) Neue verwendung von citreamicinen
JPS536351A (en) Stabilized rubber compositions
GB9512005D0 (en) Slip casting
MX9706627A (es) Derivado de tiazolidinona opticamente activo.
MX9709634A (es) Nuevos fotoiniciadores de alfa-aminoacetofenona.
TW366344B (en) Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives and pharmaceutical composition using the same
FI901723A (fi) Anordning foer upprullning och avrullning av staengselnaet.