KR900011762A - 1-헤테로아릴-3-아실-2-옥스인돌 소염제 - Google Patents
1-헤테로아릴-3-아실-2-옥스인돌 소염제Info
- Publication number
- KR900011762A KR900011762A KR1019900000165A KR900000165A KR900011762A KR 900011762 A KR900011762 A KR 900011762A KR 1019900000165 A KR1019900000165 A KR 1019900000165A KR 900000165 A KR900000165 A KR 900000165A KR 900011762 A KR900011762 A KR 900011762A
- Authority
- KR
- South Korea
- Prior art keywords
- heteroaryl
- acyl
- oxindole
- inflammatory agent
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| USPCT/US89/00079 | 1989-01-10 | ||
| PCT/US1989/000079 WO1990008145A1 (en) | 1989-01-10 | 1989-01-10 | Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR900011762A true KR900011762A (ko) | 1990-08-02 |
| KR920006785B1 KR920006785B1 (ko) | 1992-08-17 |
Family
ID=22214772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019900000165A KR920006785B1 (ko) | 1989-01-10 | 1990-01-09 | 1-헤테로아릴-3-아실-2-옥스인돌 소염제 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0378358B1 (ko) |
| JP (1) | JPH0692400B2 (ko) |
| KR (1) | KR920006785B1 (ko) |
| AT (1) | ATE96793T1 (ko) |
| AU (1) | AU616336B2 (ko) |
| CA (1) | CA2007655C (ko) |
| DE (1) | DE69004272T2 (ko) |
| DK (1) | DK0378358T3 (ko) |
| ES (1) | ES2060007T3 (ko) |
| FI (1) | FI92827C (ko) |
| HU (1) | HU215112B (ko) |
| IE (1) | IE62143B1 (ko) |
| IL (1) | IL92962A (ko) |
| NO (1) | NO179103C (ko) |
| NZ (1) | NZ232039A (ko) |
| PT (1) | PT92800B (ko) |
| WO (1) | WO1990008145A1 (ko) |
| ZA (1) | ZA90139B (ko) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2886541A1 (en) | 2013-12-19 | 2015-06-24 | Sanofi | Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases |
| CN108456205B (zh) * | 2018-05-21 | 2021-06-04 | 深圳市众康动保科技有限公司 | 一种3,3二取代羟基吲哚化合物的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4053613A (en) * | 1975-09-17 | 1977-10-11 | E. R. Squibb & Sons, Inc. | 1,3,thiazolinyl and 1,3 thiazinyl substituted indolinones |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| DE3582890D1 (de) * | 1984-02-07 | 1991-06-20 | Pfizer | 2-oxindolzwischenprodukte. |
| IN163263B (ko) * | 1984-02-07 | 1988-08-27 | Pfizer | |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| HU203350B (en) * | 1984-08-24 | 1991-07-29 | Pfizer | Process for producing antiinflammatory tricyclic oxindole derivatives |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4686224A (en) * | 1984-10-31 | 1987-08-11 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4752609A (en) * | 1985-06-20 | 1988-06-21 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
-
1989
- 1989-01-10 WO PCT/US1989/000079 patent/WO1990008145A1/en active IP Right Grant
- 1989-01-10 HU HU891086A patent/HU215112B/hu not_active IP Right Cessation
-
1990
- 1990-01-03 IL IL9296290A patent/IL92962A/en not_active IP Right Cessation
- 1990-01-08 PT PT92800A patent/PT92800B/pt not_active IP Right Cessation
- 1990-01-08 NZ NZ232039A patent/NZ232039A/en unknown
- 1990-01-09 AT AT90300229T patent/ATE96793T1/de not_active IP Right Cessation
- 1990-01-09 ES ES90300229T patent/ES2060007T3/es not_active Expired - Lifetime
- 1990-01-09 DE DE90300229T patent/DE69004272T2/de not_active Expired - Fee Related
- 1990-01-09 EP EP90300229A patent/EP0378358B1/en not_active Expired - Lifetime
- 1990-01-09 KR KR1019900000165A patent/KR920006785B1/ko not_active IP Right Cessation
- 1990-01-09 IE IE7590A patent/IE62143B1/en not_active IP Right Cessation
- 1990-01-09 ZA ZA90139A patent/ZA90139B/xx unknown
- 1990-01-09 AU AU47816/90A patent/AU616336B2/en not_active Ceased
- 1990-01-09 DK DK90300229.3T patent/DK0378358T3/da active
- 1990-01-10 JP JP2003286A patent/JPH0692400B2/ja not_active Expired - Fee Related
- 1990-01-12 CA CA002007655A patent/CA2007655C/en not_active Expired - Fee Related
-
1991
- 1991-07-09 NO NO912694A patent/NO179103C/no not_active IP Right Cessation
- 1991-07-09 FI FI913324A patent/FI92827C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0378358B1 (en) | 1993-11-03 |
| NO912694D0 (no) | 1991-07-09 |
| IE62143B1 (en) | 1994-12-14 |
| ATE96793T1 (de) | 1993-11-15 |
| EP0378358A1 (en) | 1990-07-18 |
| FI92827C (fi) | 1995-01-10 |
| IL92962A (en) | 1995-01-24 |
| WO1990008145A1 (en) | 1990-07-26 |
| DE69004272T2 (de) | 1994-02-24 |
| DE69004272D1 (de) | 1993-12-09 |
| JPH02270868A (ja) | 1990-11-05 |
| ZA90139B (en) | 1991-08-28 |
| PT92800A (pt) | 1990-07-31 |
| AU4781690A (en) | 1990-07-19 |
| HUT62292A (en) | 1993-04-28 |
| NO179103C (no) | 1996-08-07 |
| HU215112B (hu) | 1998-12-28 |
| PT92800B (pt) | 1995-12-29 |
| CA2007655A1 (en) | 1991-07-12 |
| IE900075L (en) | 1990-07-10 |
| FI92827B (fi) | 1994-09-30 |
| AU616336B2 (en) | 1991-10-24 |
| JPH0692400B2 (ja) | 1994-11-16 |
| NZ232039A (en) | 1991-07-26 |
| KR920006785B1 (ko) | 1992-08-17 |
| ES2060007T3 (es) | 1994-11-16 |
| NO179103B (no) | 1996-04-29 |
| NO912694L (no) | 1991-07-09 |
| DK0378358T3 (da) | 1993-12-06 |
| CA2007655C (en) | 1996-10-22 |
| FI913324A0 (fi) | 1991-07-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2910600A (en) | Phenyl urea and phenyl thiourea derivatives | |
| FI952680A0 (fi) | Injektoitavia taksaanijohdannaisiin pohjautuvia koostumuksia | |
| ATE270103T1 (de) | Aminophenoxyessigsäure derivate als neuroschützende mittel | |
| CO5040088A1 (es) | Nuevos compuestos y usos anestesicos locales | |
| DK1042319T3 (da) | Dihydrobenzofuraner | |
| KR900011762A (ko) | 1-헤테로아릴-3-아실-2-옥스인돌 소염제 | |
| AR020950A1 (es) | Compuestos de 3-(fenil sustituido)-5-tienil-1,2,4-triazolo con actividad contra la mosca blanca | |
| BR9612196A (pt) | Tiazolinas substituidas | |
| DK0378357T3 (da) | Antiinflammatoriske 1-heteroaryl-oxindol-3-carboxamider | |
| EP0365194A3 (en) | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides | |
| ATE263560T1 (de) | Neue verwendung von citreamicinen | |
| DE69332232D1 (de) | Immunsuppressive Enpyranosederivate | |
| GB9512005D0 (en) | Slip casting | |
| MX9706627A (es) | Derivado de tiazolidinona opticamente activo. | |
| KR927003511A (ko) | 5-리폭시게나제 억제제로서의 2-아릴메틸-1-나프톨 유도체의 에스테르 | |
| TW366344B (en) | Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives and pharmaceutical composition using the same | |
| NO934399L (no) | Tioesterderivater av 3'-O-propargyl-trifluortymidin, fremgangsmåte for fremstilling samt anvendelse av slike |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E601 | Decision to refuse application | ||
| E902 | Notification of reason for refusal | ||
| J2X1 | Appeal (before the patent court) |
Free format text: APPEAL AGAINST DECISION TO DECLINE REFUSAL |
|
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 20030711 Year of fee payment: 12 |
|
| LAPS | Lapse due to unpaid annual fee |