NO912694D0 - Anti-inflammatoriske 1-heteroaryl-3-azyl-2-oksindoler. - Google Patents

Anti-inflammatoriske 1-heteroaryl-3-azyl-2-oksindoler.

Info

Publication number
NO912694D0
NO912694D0 NO1991912694A NO912694A NO912694D0 NO 912694 D0 NO912694 D0 NO 912694D0 NO 1991912694 A NO1991912694 A NO 1991912694A NO 912694 A NO912694 A NO 912694A NO 912694 D0 NO912694 D0 NO 912694D0
Authority
NO
Norway
Prior art keywords
heteroaryl
alkyl
formula
azyl
indoles
Prior art date
Application number
NO1991912694A
Other languages
English (en)
Other versions
NO179103C (no
NO179103B (no
NO912694L (no
Inventor
Avthony Marfat
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO912694D0 publication Critical patent/NO912694D0/no
Publication of NO912694L publication Critical patent/NO912694L/no
Publication of NO179103B publication Critical patent/NO179103B/no
Publication of NO179103C publication Critical patent/NO179103C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
NO912694A 1989-01-10 1991-07-09 Fremgangsmåte for fremstilling av antiinflammatoriske 1-heteroaryl-3-acyl-2-oksindoler NO179103C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/000079 WO1990008145A1 (en) 1989-01-10 1989-01-10 Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles

Publications (4)

Publication Number Publication Date
NO912694D0 true NO912694D0 (no) 1991-07-09
NO912694L NO912694L (no) 1991-07-09
NO179103B NO179103B (no) 1996-04-29
NO179103C NO179103C (no) 1996-08-07

Family

ID=22214772

Family Applications (1)

Application Number Title Priority Date Filing Date
NO912694A NO179103C (no) 1989-01-10 1991-07-09 Fremgangsmåte for fremstilling av antiinflammatoriske 1-heteroaryl-3-acyl-2-oksindoler

Country Status (18)

Country Link
EP (1) EP0378358B1 (no)
JP (1) JPH0692400B2 (no)
KR (1) KR920006785B1 (no)
AT (1) ATE96793T1 (no)
AU (1) AU616336B2 (no)
CA (1) CA2007655C (no)
DE (1) DE69004272T2 (no)
DK (1) DK0378358T3 (no)
ES (1) ES2060007T3 (no)
FI (1) FI92827C (no)
HU (1) HU215112B (no)
IE (1) IE62143B1 (no)
IL (1) IL92962A (no)
NO (1) NO179103C (no)
NZ (1) NZ232039A (no)
PT (1) PT92800B (no)
WO (1) WO1990008145A1 (no)
ZA (1) ZA90139B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2886541A1 (en) 2013-12-19 2015-06-24 Sanofi Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases
CN108456205B (zh) * 2018-05-21 2021-06-04 深圳市众康动保科技有限公司 一种3,3二取代羟基吲哚化合物的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053613A (en) * 1975-09-17 1977-10-11 E. R. Squibb & Sons, Inc. 1,3,thiazolinyl and 1,3 thiazinyl substituted indolinones
US4721712A (en) * 1984-06-12 1988-01-26 Pfizer Inc. 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents
DE3582890D1 (de) * 1984-02-07 1991-06-20 Pfizer 2-oxindolzwischenprodukte.
IN163263B (no) * 1984-02-07 1988-08-27 Pfizer
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
HU203350B (en) * 1984-08-24 1991-07-29 Pfizer Process for producing antiinflammatory tricyclic oxindole derivatives
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
US4752609A (en) * 1985-06-20 1988-06-21 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds

Also Published As

Publication number Publication date
EP0378358B1 (en) 1993-11-03
IE62143B1 (en) 1994-12-14
ATE96793T1 (de) 1993-11-15
EP0378358A1 (en) 1990-07-18
FI92827C (fi) 1995-01-10
IL92962A (en) 1995-01-24
WO1990008145A1 (en) 1990-07-26
DE69004272T2 (de) 1994-02-24
DE69004272D1 (de) 1993-12-09
JPH02270868A (ja) 1990-11-05
ZA90139B (en) 1991-08-28
PT92800A (pt) 1990-07-31
AU4781690A (en) 1990-07-19
HUT62292A (en) 1993-04-28
NO179103C (no) 1996-08-07
HU215112B (hu) 1998-12-28
PT92800B (pt) 1995-12-29
CA2007655A1 (en) 1991-07-12
IE900075L (en) 1990-07-10
FI92827B (fi) 1994-09-30
AU616336B2 (en) 1991-10-24
KR900011762A (ko) 1990-08-02
JPH0692400B2 (ja) 1994-11-16
NZ232039A (en) 1991-07-26
KR920006785B1 (ko) 1992-08-17
ES2060007T3 (es) 1994-11-16
NO179103B (no) 1996-04-29
NO912694L (no) 1991-07-09
DK0378358T3 (da) 1993-12-06
CA2007655C (en) 1996-10-22
FI913324A0 (fi) 1991-07-09

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