PT92800A - Processo para a preparacao de 1-heteroaril-3-acil-2-oxindoles uteis como anti-inflamatorios - Google Patents
Processo para a preparacao de 1-heteroaril-3-acil-2-oxindoles uteis como anti-inflamatoriosInfo
- Publication number
- PT92800A PT92800A PT92800A PT9280090A PT92800A PT 92800 A PT92800 A PT 92800A PT 92800 A PT92800 A PT 92800A PT 9280090 A PT9280090 A PT 9280090A PT 92800 A PT92800 A PT 92800A
- Authority
- PT
- Portugal
- Prior art keywords
- oxindoles
- acyl
- heteroaril
- uti
- inflammatory
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1989/000079 WO1990008145A1 (en) | 1989-01-10 | 1989-01-10 | Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT92800A true PT92800A (pt) | 1990-07-31 |
| PT92800B PT92800B (pt) | 1995-12-29 |
Family
ID=22214772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT92800A PT92800B (pt) | 1989-01-10 | 1990-01-08 | Processo para a preparacao de 1-heteroaril-3-acil-2-oxindoles uteis como anti-inflamatorios |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0378358B1 (pt) |
| JP (1) | JPH0692400B2 (pt) |
| KR (1) | KR920006785B1 (pt) |
| AT (1) | ATE96793T1 (pt) |
| AU (1) | AU616336B2 (pt) |
| CA (1) | CA2007655C (pt) |
| DE (1) | DE69004272T2 (pt) |
| DK (1) | DK0378358T3 (pt) |
| ES (1) | ES2060007T3 (pt) |
| FI (1) | FI92827C (pt) |
| HU (1) | HU215112B (pt) |
| IE (1) | IE62143B1 (pt) |
| IL (1) | IL92962A (pt) |
| NO (1) | NO179103C (pt) |
| NZ (1) | NZ232039A (pt) |
| PT (1) | PT92800B (pt) |
| WO (1) | WO1990008145A1 (pt) |
| ZA (1) | ZA90139B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2886541A1 (en) * | 2013-12-19 | 2015-06-24 | Sanofi | Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases |
| CN108456205B (zh) * | 2018-05-21 | 2021-06-04 | 深圳市众康动保科技有限公司 | 一种3,3二取代羟基吲哚化合物的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4053613A (en) * | 1975-09-17 | 1977-10-11 | E. R. Squibb & Sons, Inc. | 1,3,thiazolinyl and 1,3 thiazinyl substituted indolinones |
| ATE63543T1 (de) * | 1984-02-07 | 1991-06-15 | Pfizer | 2-oxindolzwischenprodukte. |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| IN163263B (pt) * | 1984-02-07 | 1988-08-27 | Pfizer | |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| HU203350B (en) * | 1984-08-24 | 1991-07-29 | Pfizer | Process for producing antiinflammatory tricyclic oxindole derivatives |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4686224A (en) * | 1984-10-31 | 1987-08-11 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4752609A (en) * | 1985-06-20 | 1988-06-21 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
-
1989
- 1989-01-10 HU HU891086A patent/HU215112B/hu not_active IP Right Cessation
- 1989-01-10 WO PCT/US1989/000079 patent/WO1990008145A1/en active IP Right Grant
-
1990
- 1990-01-03 IL IL9296290A patent/IL92962A/en not_active IP Right Cessation
- 1990-01-08 PT PT92800A patent/PT92800B/pt not_active IP Right Cessation
- 1990-01-08 NZ NZ232039A patent/NZ232039A/en unknown
- 1990-01-09 DE DE90300229T patent/DE69004272T2/de not_active Expired - Fee Related
- 1990-01-09 EP EP90300229A patent/EP0378358B1/en not_active Expired - Lifetime
- 1990-01-09 AT AT90300229T patent/ATE96793T1/de not_active IP Right Cessation
- 1990-01-09 ZA ZA90139A patent/ZA90139B/xx unknown
- 1990-01-09 AU AU47816/90A patent/AU616336B2/en not_active Ceased
- 1990-01-09 ES ES90300229T patent/ES2060007T3/es not_active Expired - Lifetime
- 1990-01-09 IE IE7590A patent/IE62143B1/en not_active IP Right Cessation
- 1990-01-09 KR KR1019900000165A patent/KR920006785B1/ko not_active IP Right Cessation
- 1990-01-09 DK DK90300229.3T patent/DK0378358T3/da active
- 1990-01-10 JP JP2003286A patent/JPH0692400B2/ja not_active Expired - Fee Related
- 1990-01-12 CA CA002007655A patent/CA2007655C/en not_active Expired - Fee Related
-
1991
- 1991-07-09 FI FI913324A patent/FI92827C/fi not_active IP Right Cessation
- 1991-07-09 NO NO912694A patent/NO179103C/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2007655A1 (en) | 1991-07-12 |
| NO179103C (no) | 1996-08-07 |
| DE69004272T2 (de) | 1994-02-24 |
| AU4781690A (en) | 1990-07-19 |
| HU215112B (hu) | 1998-12-28 |
| FI92827C (fi) | 1995-01-10 |
| JPH02270868A (ja) | 1990-11-05 |
| KR900011762A (ko) | 1990-08-02 |
| ATE96793T1 (de) | 1993-11-15 |
| CA2007655C (en) | 1996-10-22 |
| ZA90139B (en) | 1991-08-28 |
| HUT62292A (en) | 1993-04-28 |
| KR920006785B1 (ko) | 1992-08-17 |
| FI913324A0 (fi) | 1991-07-09 |
| IL92962A (en) | 1995-01-24 |
| IE900075L (en) | 1990-07-10 |
| AU616336B2 (en) | 1991-10-24 |
| NO912694D0 (no) | 1991-07-09 |
| IE62143B1 (en) | 1994-12-14 |
| NO179103B (no) | 1996-04-29 |
| DK0378358T3 (da) | 1993-12-06 |
| NZ232039A (en) | 1991-07-26 |
| ES2060007T3 (es) | 1994-11-16 |
| JPH0692400B2 (ja) | 1994-11-16 |
| NO912694L (no) | 1991-07-09 |
| PT92800B (pt) | 1995-12-29 |
| EP0378358A1 (en) | 1990-07-18 |
| DE69004272D1 (de) | 1993-12-09 |
| EP0378358B1 (en) | 1993-11-03 |
| WO1990008145A1 (en) | 1990-07-26 |
| FI92827B (fi) | 1994-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19950913 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20050314 |