PT92801A - Processo para a preparacao de 1-heteroaril-oxindole-3-carboxamidas uteis como anti-inflamatorios - Google Patents
Processo para a preparacao de 1-heteroaril-oxindole-3-carboxamidas uteis como anti-inflamatoriosInfo
- Publication number
- PT92801A PT92801A PT92801A PT9280190A PT92801A PT 92801 A PT92801 A PT 92801A PT 92801 A PT92801 A PT 92801A PT 9280190 A PT9280190 A PT 9280190A PT 92801 A PT92801 A PT 92801A
- Authority
- PT
- Portugal
- Prior art keywords
- furyl
- thienyl
- alkyl
- utih
- oxindole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1989/000080 WO1990008146A1 (en) | 1989-01-10 | 1989-01-10 | Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT92801A true PT92801A (pt) | 1990-07-31 |
| PT92801B PT92801B (pt) | 1995-12-29 |
Family
ID=22214773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT92801A PT92801B (pt) | 1989-01-10 | 1990-01-08 | Processo para a preparacao de 1-heteroaril-oxindole-3-carboxamidas uteis como anti-inflamatorios |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5128352A (pt) |
| EP (1) | EP0378357B1 (pt) |
| JP (1) | JPH0678337B2 (pt) |
| KR (1) | KR920006784B1 (pt) |
| AT (1) | ATE100096T1 (pt) |
| AU (1) | AU616090B2 (pt) |
| CA (1) | CA2007651C (pt) |
| DE (1) | DE69005833T2 (pt) |
| DK (1) | DK0378357T3 (pt) |
| ES (1) | ES2062318T3 (pt) |
| FI (1) | FI94247C (pt) |
| HU (1) | HU217072B (pt) |
| IE (1) | IE61796B1 (pt) |
| IL (1) | IL92961A0 (pt) |
| MY (1) | MY106261A (pt) |
| NO (1) | NO178193C (pt) |
| NZ (1) | NZ232038A (pt) |
| PT (1) | PT92801B (pt) |
| WO (1) | WO1990008146A1 (pt) |
| ZA (1) | ZA90140B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136839A (en) * | 1995-06-12 | 2000-10-24 | G. D. Searle & Co. | Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor |
| HUE055662T2 (hu) * | 2014-12-29 | 2021-12-28 | Us Health | Laktát-dehidrogenáz kismolekulás inhibitorai és alkalmazási eljárásai |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| US4176191A (en) * | 1977-09-06 | 1979-11-27 | Abbott Laboratories | Aminomethylene oxindoles |
| US4476307A (en) * | 1982-09-20 | 1984-10-09 | Pfizer Inc. | Heteroylidene indolone compounds |
| DE3568776D1 (en) * | 1984-02-07 | 1989-04-20 | Pfizer | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| WO1986001510A1 (en) * | 1984-08-24 | 1986-03-13 | Pfizer Inc. | Tricyclic oxindole antiinflammatory agents |
| US4644005A (en) * | 1984-10-31 | 1987-02-17 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4686224A (en) * | 1984-10-31 | 1987-08-11 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4791129A (en) * | 1987-01-20 | 1988-12-13 | Pfizer Inc. | 1,3-dicarboxamidooxindoles as analgesic and antiinflammatory agents |
-
1989
- 1989-01-10 WO PCT/US1989/000080 patent/WO1990008146A1/en active IP Right Grant
- 1989-01-10 HU HU892128A patent/HU217072B/hu not_active IP Right Cessation
- 1989-01-10 US US07/721,495 patent/US5128352A/en not_active Expired - Lifetime
-
1990
- 1990-01-03 IL IL92961A patent/IL92961A0/xx not_active IP Right Cessation
- 1990-01-08 NZ NZ232038A patent/NZ232038A/en unknown
- 1990-01-08 PT PT92801A patent/PT92801B/pt not_active IP Right Cessation
- 1990-01-08 MY MYPI90000022A patent/MY106261A/en unknown
- 1990-01-09 EP EP90300228A patent/EP0378357B1/en not_active Expired - Lifetime
- 1990-01-09 IE IE7490A patent/IE61796B1/en not_active IP Right Cessation
- 1990-01-09 AU AU47817/90A patent/AU616090B2/en not_active Ceased
- 1990-01-09 ES ES90300228T patent/ES2062318T3/es not_active Expired - Lifetime
- 1990-01-09 ZA ZA90140A patent/ZA90140B/xx unknown
- 1990-01-09 DE DE90300228T patent/DE69005833T2/de not_active Expired - Fee Related
- 1990-01-09 DK DK90300228.5T patent/DK0378357T3/da active
- 1990-01-09 AT AT90300228T patent/ATE100096T1/de not_active IP Right Cessation
- 1990-01-09 KR KR1019900000166A patent/KR920006784B1/ko not_active IP Right Cessation
- 1990-01-10 JP JP2003287A patent/JPH0678337B2/ja not_active Expired - Lifetime
- 1990-01-12 CA CA002007651A patent/CA2007651C/en not_active Expired - Fee Related
-
1991
- 1991-07-09 FI FI913325A patent/FI94247C/fi not_active IP Right Cessation
- 1991-07-09 NO NO912696A patent/NO178193C/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4781790A (en) | 1990-07-19 |
| KR920006784B1 (ko) | 1992-08-17 |
| MY106261A (en) | 1995-04-29 |
| DE69005833T2 (de) | 1994-04-28 |
| NO178193B (no) | 1995-10-30 |
| EP0378357A1 (en) | 1990-07-18 |
| AU616090B2 (en) | 1991-10-17 |
| HUT58084A (en) | 1992-01-28 |
| ZA90140B (en) | 1991-08-28 |
| EP0378357B1 (en) | 1994-01-12 |
| NZ232038A (en) | 1991-06-25 |
| US5128352A (en) | 1992-07-07 |
| FI94247C (fi) | 1995-08-10 |
| DK0378357T3 (da) | 1994-02-14 |
| WO1990008146A1 (en) | 1990-07-26 |
| ATE100096T1 (de) | 1994-01-15 |
| PT92801B (pt) | 1995-12-29 |
| CA2007651C (en) | 1997-08-19 |
| IL92961A0 (en) | 1990-09-17 |
| DE69005833D1 (de) | 1994-02-24 |
| IE900074L (en) | 1990-07-10 |
| NO912696D0 (no) | 1991-07-09 |
| NO178193C (no) | 1996-02-07 |
| FI94247B (fi) | 1995-04-28 |
| FI913325A0 (fi) | 1991-07-09 |
| JPH0678337B2 (ja) | 1994-10-05 |
| KR900011763A (ko) | 1990-08-02 |
| IE61796B1 (en) | 1994-11-30 |
| CA2007651A1 (en) | 1991-07-12 |
| HU217072B (hu) | 1999-11-29 |
| NO912696L (no) | 1991-07-09 |
| ES2062318T3 (es) | 1994-12-16 |
| JPH02247174A (ja) | 1990-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19950919 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20050321 |