FI964914A0 - 2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistamiseksi - Google Patents

2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistamiseksi

Info

Publication number
FI964914A0
FI964914A0 FI964914A FI964914A FI964914A0 FI 964914 A0 FI964914 A0 FI 964914A0 FI 964914 A FI964914 A FI 964914A FI 964914 A FI964914 A FI 964914A FI 964914 A0 FI964914 A0 FI 964914A0
Authority
FI
Finland
Prior art keywords
beta
amino
thiophenes
aroyl
benzo
Prior art date
Application number
FI964914A
Other languages
English (en)
Swedish (sv)
Other versions
FI964914A (fi
Inventor
Alexander Glenn Godfrey
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI964914A publication Critical patent/FI964914A/fi
Publication of FI964914A0 publication Critical patent/FI964914A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cephalosporin Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
FI964914A 1994-06-10 1996-12-09 2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistamiseksi FI964914A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/257,859 US5466810A (en) 1994-06-10 1994-06-10 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[β]thiophenes
PCT/US1995/007397 WO1995034557A1 (en) 1994-06-10 1995-06-07 2-AMINO-3-AROYL-BENZO[β]THIOPHENES AND METHOD OF MAKING THE SAME

Publications (2)

Publication Number Publication Date
FI964914A FI964914A (fi) 1996-12-09
FI964914A0 true FI964914A0 (fi) 1996-12-09

Family

ID=22978079

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964914A FI964914A0 (fi) 1994-06-10 1996-12-09 2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistamiseksi

Country Status (14)

Country Link
US (3) US5466810A (fi)
EP (1) EP0765321B1 (fi)
JP (1) JPH10502057A (fi)
AT (1) ATE200671T1 (fi)
AU (1) AU2702995A (fi)
BR (1) BR9507956A (fi)
CA (1) CA2192097A1 (fi)
DE (1) DE69520738T2 (fi)
DK (1) DK0765321T3 (fi)
ES (1) ES2155891T3 (fi)
FI (1) FI964914A0 (fi)
GR (1) GR3036028T3 (fi)
PT (1) PT765321E (fi)
WO (1) WO1995034557A1 (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5606075A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
CA2223595C (en) 1995-06-07 2008-08-05 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
CA2207141A1 (en) * 1996-07-15 1998-01-15 David Thompson Berg Benzothiophene compounds, and uses and formulations thereof
US5792798A (en) * 1996-07-29 1998-08-11 Eli Lilly And Company Method for inhibiting plasminogen activator inhibitor 1
ZA9710262B (en) * 1996-11-19 1999-05-13 Lilly Co Eli Process for the synthesis of benzothiophenes
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
HUP0200871A3 (en) 1999-05-04 2004-04-28 Strakan Int Ltd Androgen glycosides and androgenic activity thereof
US6232260B1 (en) 1999-10-14 2001-05-15 Equistar Chemicals, L.P. Single-site catalysts for olefin polymerization
US7144885B2 (en) * 2002-02-22 2006-12-05 Bayer Pharmaceuticals Corporation Fused tricyclic heterocycles useful for treating hyper-proliferative disorders
NZ534255A (en) * 2002-02-22 2007-06-29 Bayer Pharmaceuticals Corp Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
US20100125073A1 (en) * 2006-09-01 2010-05-20 Olaf Weber Benzofuran and benzothiophene derivatives useful in the treatment of cancers of the central nervous system
WO2011109679A2 (en) * 2010-03-05 2011-09-09 Amira Pharmaceuticals, Inc. Inhibitors of 5-lipoxygenase
CN102653520A (zh) * 2012-04-10 2012-09-05 苏州大学 一种2-羟基-2-芳基硫代乙酰胺的制备方法
EP3519170B1 (en) * 2016-09-27 2023-08-16 DSM IP Assets B.V. Transparent drawn article

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US5420349A (en) * 1994-06-10 1995-05-30 Eli Lilly And Company 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-]benzo[4-(2-aminoethoxy)-benzoyl[β]thiophenes

Also Published As

Publication number Publication date
GR3036028T3 (en) 2001-09-28
EP0765321A4 (fi) 1997-05-02
WO1995034557A1 (en) 1995-12-21
DE69520738T2 (de) 2001-09-13
US5554755A (en) 1996-09-10
AU2702995A (en) 1996-01-05
PT765321E (pt) 2001-07-31
US5466810A (en) 1995-11-14
JPH10502057A (ja) 1998-02-24
FI964914A (fi) 1996-12-09
EP0765321B1 (en) 2001-04-18
DK0765321T3 (da) 2001-05-07
ES2155891T3 (es) 2001-06-01
DE69520738D1 (de) 2001-05-23
US5792870A (en) 1998-08-11
ATE200671T1 (de) 2001-05-15
BR9507956A (pt) 1997-08-12
CA2192097A1 (en) 1995-12-21
EP0765321A1 (en) 1997-04-02

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