IL91826A - Human growth hormone analog - Google Patents
Human growth hormone analogInfo
- Publication number
- IL91826A IL91826A IL91826A IL9182684A IL91826A IL 91826 A IL91826 A IL 91826A IL 91826 A IL91826 A IL 91826A IL 9182684 A IL9182684 A IL 9182684A IL 91826 A IL91826 A IL 91826A
- Authority
- IL
- Israel
- Prior art keywords
- host cell
- growth hormone
- human growth
- hormone analog
- superoxide dismutase
- Prior art date
Links
- 102000002265 Human Growth Hormone Human genes 0.000 title 1
- 108010000521 Human Growth Hormone Proteins 0.000 title 1
- 239000000854 Human Growth Hormone Substances 0.000 title 1
- 102000019197 Superoxide Dismutase Human genes 0.000 abstract 2
- 108010012715 Superoxide dismutase Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Enzymes And Modification Thereof (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51418883A | 1983-07-15 | 1983-07-15 | |
IL72396A IL72396A (en) | 1983-07-15 | 1984-07-12 | Expression vectors for enhanced production of polypeptides,plasmids containing the vectors,hosts containing the plasmids and products manufactured thereby |
Publications (1)
Publication Number | Publication Date |
---|---|
IL91826A true IL91826A (en) | 1992-05-25 |
Family
ID=24046152
Family Applications (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL91826A IL91826A (en) | 1983-07-15 | 1984-07-12 | Human growth hormone analog |
IL91828A IL91828A (en) | 1983-07-15 | 1984-07-12 | Method of isolating and purifying animal growth hormones or analogs thereof produced by genetically engineered bacteria |
IL72396A IL72396A (en) | 1983-07-15 | 1984-07-12 | Expression vectors for enhanced production of polypeptides,plasmids containing the vectors,hosts containing the plasmids and products manufactured thereby |
IL91828A IL91828A0 (en) | 1983-07-15 | 1989-09-28 | Method of isolating and purifying animal growth hormones or analogs thereof produced by genetically engineered bacteria |
IL91826A IL91826A0 (en) | 1983-07-15 | 1989-09-28 | Human growth hormone analogs |
IL101629A IL101629A0 (en) | 1983-07-15 | 1992-04-17 | Expression vectors for enhanced production of polypeptides,plasmids containing the vectors,hosts containing the plasmids,products manufactured thereby and related methods |
IL10810893A IL108108A0 (en) | 1983-07-15 | 1993-12-21 | Expression vectors and related methods |
IL11217894A IL112178A0 (en) | 1983-07-15 | 1994-12-29 | Expression plasmid having unique insertion site |
Family Applications After (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL91828A IL91828A (en) | 1983-07-15 | 1984-07-12 | Method of isolating and purifying animal growth hormones or analogs thereof produced by genetically engineered bacteria |
IL72396A IL72396A (en) | 1983-07-15 | 1984-07-12 | Expression vectors for enhanced production of polypeptides,plasmids containing the vectors,hosts containing the plasmids and products manufactured thereby |
IL91828A IL91828A0 (en) | 1983-07-15 | 1989-09-28 | Method of isolating and purifying animal growth hormones or analogs thereof produced by genetically engineered bacteria |
IL91826A IL91826A0 (en) | 1983-07-15 | 1989-09-28 | Human growth hormone analogs |
IL101629A IL101629A0 (en) | 1983-07-15 | 1992-04-17 | Expression vectors for enhanced production of polypeptides,plasmids containing the vectors,hosts containing the plasmids,products manufactured thereby and related methods |
IL10810893A IL108108A0 (en) | 1983-07-15 | 1993-12-21 | Expression vectors and related methods |
IL11217894A IL112178A0 (en) | 1983-07-15 | 1994-12-29 | Expression plasmid having unique insertion site |
Country Status (22)
Country | Link |
---|---|
US (3) | US4871835A (sv) |
EP (3) | EP0691406A1 (sv) |
JP (3) | JPH0687780B2 (sv) |
AT (2) | ATE66959T1 (sv) |
AU (2) | AU577298B2 (sv) |
BG (2) | BG49718A3 (sv) |
BR (1) | BR8403523A (sv) |
CA (1) | CA1254527A (sv) |
CZ (1) | CZ282867B6 (sv) |
DD (2) | DD229427A5 (sv) |
DE (2) | DE3486425T2 (sv) |
DK (1) | DK347184A (sv) |
ES (2) | ES534321A0 (sv) |
FI (1) | FI90564C (sv) |
HK (1) | HK128095A (sv) |
HU (1) | HU209878B (sv) |
IE (2) | IE64174B1 (sv) |
IL (8) | IL91826A (sv) |
NZ (2) | NZ208897A (sv) |
RO (1) | RO91332B (sv) |
SK (1) | SK524684A3 (sv) |
ZA (1) | ZA845345B (sv) |
Families Citing this family (67)
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DE3585170D1 (de) * | 1984-03-06 | 1992-02-27 | Lilly Co Eli | Expressionsvektoren fuer rinderwachstumshormonderivate. |
CA1267615A (en) * | 1984-08-27 | 1990-04-10 | Dan Hadary | Method for recovering purified growth hormones from genetically engineered microorganisms |
US5112744A (en) * | 1984-08-27 | 1992-05-12 | Bio-Technology General Corp. | Plasmids for the production of human Cu-Zn superoxide dismutase, bacterial hosts containing the plasmids and methods for production and recovery of such superoxide dismutase |
CA1340597C (en) * | 1984-08-27 | 1999-06-22 | Haim Aviv | Expression vectors containing pl promoter, and engineered restriction site for convenient replacement of ribosomal binding site, plasmids containing the vectors, hosts containing the plasmids and related methods |
US5162217A (en) * | 1984-08-27 | 1992-11-10 | Bio-Technology General Corp. | Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda PL promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof |
US6030611A (en) * | 1984-08-27 | 2000-02-29 | Bio-Technology General Corp. | Therapeutic SOD compositions and uses thereof |
US5143836A (en) * | 1984-08-27 | 1992-09-01 | Bio-Technology General Corp. | Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda pl promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof |
US5759816A (en) * | 1984-08-27 | 1998-06-02 | Bio-Technology General Corp. | Expression vectors containing λPL promoter and T1 T2 rRNA termination sequence plasmids containing the vectors hosts containing the plasmids and related methods |
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WO1990005185A1 (fr) * | 1988-11-07 | 1990-05-17 | L'universite De L'etat A Liege | Hormone de croissance humaine modifiee |
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US5958879A (en) * | 1989-10-12 | 1999-09-28 | Ohio University/Edison Biotechnology Institute | Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal |
US6583115B1 (en) | 1989-10-12 | 2003-06-24 | Ohio University/Edison Biotechnology Institute | Methods for treating acromegaly and giantism with growth hormone antagonists |
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DE69712124T2 (de) | 1996-02-13 | 2002-12-12 | Jcr Pharmaceutical Co., Ltd. | Hormones de croissance humaines mutantes et leur utilisation |
CA2303395C (en) * | 1997-09-08 | 2008-12-02 | Metabolic Pharmaceuticals Ltd | Treatment of obesity |
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WO1984002534A1 (en) * | 1982-12-23 | 1984-07-05 | Us Commerce | Human growth hormone produced by recombinant dna in mouse cells |
US4728609A (en) * | 1983-01-10 | 1988-03-01 | Hoffmann-La-Roche Inc. | Recombinant growth hormone releasing factor |
JPS59145876A (ja) * | 1983-02-09 | 1984-08-21 | 株式会社リコー | 開閉体用のヒンジ |
AU574064B2 (en) * | 1983-03-07 | 1988-06-30 | F. Hoffmann-La Roche Ag | Growth hormone releasing factor analogues |
DE122080T1 (de) * | 1983-03-25 | 1985-05-23 | Celltech Ltd., Slough, Berkshire | Verfahren zur herstellung eines proteins. |
US4755465A (en) * | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
BG49718A3 (en) * | 1983-07-15 | 1992-01-15 | Bio- Technology General Corp | Method for preparing of polypeptid with superoxiddismutasne activitty |
AU587176B2 (en) * | 1984-02-14 | 1989-08-10 | Mycogen Plant Science, Inc. | Transfer vector |
US4767709A (en) * | 1984-06-28 | 1988-08-30 | The Johns Hopkins University | Growth-related hormones |
DE3426532A1 (de) * | 1984-07-18 | 1986-01-30 | Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig | Verwendung einer dna-sequenz zur expression sowie dna-struktur und expressionsvektor mit der dna-sequenz |
CA1340597C (en) * | 1984-08-27 | 1999-06-22 | Haim Aviv | Expression vectors containing pl promoter, and engineered restriction site for convenient replacement of ribosomal binding site, plasmids containing the vectors, hosts containing the plasmids and related methods |
US4612367A (en) * | 1985-04-08 | 1986-09-16 | Eli Lilly And Company | Process for purifying growth hormone-like materials |
US4677196A (en) * | 1985-09-06 | 1987-06-30 | International Minerals & Chemical Corp. | Purification and activation of proteins from insoluble inclusion bodies |
US4656255A (en) * | 1985-09-09 | 1987-04-07 | International Minerals & Chemical Corp. | Protein recovery |
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1984
- 1984-07-02 BG BG080683A patent/BG49718A3/xx unknown
- 1984-07-03 DE DE3486425T patent/DE3486425T2/de not_active Expired - Lifetime
- 1984-07-03 DE DE8484107717T patent/DE3485003D1/de not_active Expired - Lifetime
- 1984-07-03 EP EP95114069A patent/EP0691406A1/en not_active Withdrawn
- 1984-07-03 AT AT84107717T patent/ATE66959T1/de not_active IP Right Cessation
- 1984-07-03 EP EP88121246A patent/EP0319049B1/en not_active Expired - Lifetime
- 1984-07-03 EP EP84107717A patent/EP0131843B1/en not_active Expired - Lifetime
- 1984-07-03 AT AT88121246T patent/ATE136934T1/de not_active IP Right Cessation
- 1984-07-05 CZ CS845246A patent/CZ282867B6/cs unknown
- 1984-07-05 SK SK5246-84A patent/SK524684A3/sk unknown
- 1984-07-06 AU AU30345/84A patent/AU577298B2/en not_active Expired
- 1984-07-11 ZA ZA845345A patent/ZA845345B/xx unknown
- 1984-07-12 IL IL91826A patent/IL91826A/xx unknown
- 1984-07-12 BG BG066214A patent/BG49721A3/xx unknown
- 1984-07-12 IL IL91828A patent/IL91828A/xx not_active IP Right Cessation
- 1984-07-12 IL IL72396A patent/IL72396A/xx not_active IP Right Cessation
- 1984-07-13 CA CA000458833A patent/CA1254527A/en not_active Expired
- 1984-07-13 BR BR8403523A patent/BR8403523A/pt not_active IP Right Cessation
- 1984-07-13 RO RO115224A patent/RO91332B/ro unknown
- 1984-07-13 HU HU842749A patent/HU209878B/hu unknown
- 1984-07-13 NZ NZ208897A patent/NZ208897A/xx unknown
- 1984-07-13 FI FI842842A patent/FI90564C/sv not_active IP Right Cessation
- 1984-07-13 JP JP59145876A patent/JPH0687780B2/ja not_active Expired - Lifetime
- 1984-07-13 NZ NZ227962A patent/NZ227962A/xx unknown
- 1984-07-13 DK DK347184A patent/DK347184A/da not_active Application Discontinuation
- 1984-07-13 IE IE181884A patent/IE64174B1/en not_active IP Right Cessation
- 1984-07-13 ES ES534321A patent/ES534321A0/es active Granted
- 1984-07-16 DD DD84265320A patent/DD229427A5/de not_active IP Right Cessation
- 1984-07-16 DD DD84283853A patent/DD240217A5/de not_active IP Right Cessation
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1985
- 1985-01-14 US US06/691,230 patent/US4871835A/en not_active Expired - Fee Related
- 1985-07-03 US US06/752,441 patent/US4831120A/en not_active Expired - Lifetime
- 1985-07-08 ES ES544976A patent/ES8604252A1/es not_active Expired
-
1988
- 1988-07-22 AU AU19777/88A patent/AU615663B2/en not_active Expired
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1989
- 1989-03-07 US US07/320,320 patent/US4997916A/en not_active Expired - Lifetime
- 1989-09-28 IL IL91828A patent/IL91828A0/xx unknown
- 1989-09-28 IL IL91826A patent/IL91826A0/xx unknown
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1992
- 1992-04-17 IL IL101629A patent/IL101629A0/xx unknown
- 1992-07-29 IE IE922469A patent/IE922469A1/en not_active Application Discontinuation
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1993
- 1993-12-01 JP JP5301898A patent/JP2568376B2/ja not_active Expired - Lifetime
- 1993-12-21 IL IL10810893A patent/IL108108A0/xx unknown
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1994
- 1994-12-29 IL IL11217894A patent/IL112178A0/xx unknown
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1995
- 1995-08-10 HK HK128095A patent/HK128095A/xx not_active IP Right Cessation
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1996
- 1996-07-10 JP JP18085896A patent/JP3146161B2/ja not_active Expired - Lifetime
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