IL89119A - Platinum (iv) complexes for use in the treatment of tumors and pharmaceutical compositions containing them - Google Patents
Platinum (iv) complexes for use in the treatment of tumors and pharmaceutical compositions containing themInfo
- Publication number
- IL89119A IL89119A IL8911989A IL8911989A IL89119A IL 89119 A IL89119 A IL 89119A IL 8911989 A IL8911989 A IL 8911989A IL 8911989 A IL8911989 A IL 8911989A IL 89119 A IL89119 A IL 89119A
- Authority
- IL
- Israel
- Prior art keywords
- complexes
- alkyl
- complex
- compound
- complex according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15167488A | 1988-02-02 | 1988-02-02 | |
| US29677689A | 1989-01-13 | 1989-01-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL89119A0 IL89119A0 (en) | 1989-08-15 |
| IL89119A true IL89119A (en) | 1994-04-12 |
Family
ID=26848859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL8911989A IL89119A (en) | 1988-02-02 | 1989-01-30 | Platinum (iv) complexes for use in the treatment of tumors and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0328274B1 (da) |
| JP (1) | JP2781403B2 (da) |
| KR (1) | KR0147270B1 (da) |
| AT (1) | ATE113054T1 (da) |
| AU (1) | AU618310B2 (da) |
| CA (1) | CA1340286C (da) |
| DE (1) | DE68918878T2 (da) |
| DK (1) | DK175050B1 (da) |
| ES (1) | ES2063119T3 (da) |
| FI (1) | FI91260C (da) |
| HU (1) | HU205767B (da) |
| IE (1) | IE65503B1 (da) |
| IL (1) | IL89119A (da) |
| NO (1) | NO177569C (da) |
| NZ (1) | NZ227839A (da) |
| PT (1) | PT89608B (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5196555A (en) * | 1989-10-17 | 1993-03-23 | Bristol-Myers Squibb Company | Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity |
| FI905018A7 (fi) * | 1989-10-17 | 1991-04-18 | Bristol Myers Squibb Co | Veteen ja liuottimeen liukenevat aksiaaliset hydroksi- ja mono- ja di-karboksyylihappojohdannaiset, joilla on korkea kasvainaktiivisuus |
| GB9105037D0 (en) * | 1991-03-09 | 1991-04-24 | Johnson Matthey Plc | Improvements in chemical compounds |
| IT1251115B (it) * | 1991-07-26 | 1995-05-04 | Mauro Esposito | Complessi molecolari del platino ad attivita' antitumorale |
| US5624919A (en) * | 1993-09-14 | 1997-04-29 | The University Of Vermont And State Agricultural College | Trans platinum (IV) complexes |
| EP0646589A3 (en) * | 1993-10-04 | 1995-06-28 | Tanaka Precious Metal Ind | Anti-tumor platinum (IV) complexes. |
| GB9408218D0 (en) * | 1994-04-26 | 1994-06-15 | Johnson Matthey Plc | Improvements in platinum complexes |
| GB9502799D0 (en) * | 1995-02-14 | 1995-04-05 | Johnson Matthey Plc | Improvements in platinum complexes |
| US6008395A (en) * | 1995-02-28 | 1999-12-28 | Kidani; Yoshinori | Platinum (IV) complex, production process thereof and carcinostatic agent containing the same |
| KR100246722B1 (ko) * | 1997-12-30 | 2000-04-01 | 박호군 | 경구용 백금 착화합물 항암제 및 그 제조방법 |
| CZ288912B6 (cs) * | 1998-05-27 | 2001-09-12 | Lachema, A. S. | Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující |
| EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
| CN1296377C (zh) * | 2003-06-11 | 2007-01-24 | 南京大学 | 含醚键羧酸根为配体的铂（ⅱ）配合物的制备 |
| AU2004270655B2 (en) | 2003-08-13 | 2011-03-24 | University Of South Florida | Methods for inhibiting tumor cell proliferation |
| EP1524273B1 (de) * | 2003-10-13 | 2006-11-22 | Salama, Zoser B. nat.rer.Dr. | Verfahren zur Herstellung von trans- oder cis-Diammoniumdichlorodihydroxoplatin (IV)-Salzen und -Derivaten und ihre Verwendung zur Herstellung von pharmazeutischen Wirkstoffen |
| US20050288365A1 (en) | 2004-01-06 | 2005-12-29 | Heidi Kay | Platinum complexes and methods for inhibiting tumor cell proliferation |
| US20060205810A1 (en) * | 2004-11-24 | 2006-09-14 | Schering Corporation | Platinum therapeutic combinations |
| CZ300590B6 (cs) * | 2006-06-20 | 2009-06-24 | Pliva - Lachema A. S. | Farmaceutická kompozice pro injekcní podání |
| CZ300424B6 (cs) * | 2006-06-20 | 2009-05-13 | Pliva - Lachema A. S. | Farmaceutická kompozice pro perorální podání |
| US9771387B2 (en) | 2013-07-16 | 2017-09-26 | Placon Therapeutics | Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof |
| JP6321291B2 (ja) | 2014-09-03 | 2018-05-09 | ブイユーエービー ファーマ エー．エス． | 増加した抗腫瘍効果を有する白金（ｉｖ）錯体 |
| CN107709286B (zh) * | 2015-06-24 | 2021-02-19 | 日本化药株式会社 | 新型铂(ⅳ)络合物 |
| WO2017047497A1 (ja) | 2015-09-14 | 2017-03-23 | 日本化薬株式会社 | ６配位白金錯体の高分子結合体 |
| CN105713046B (zh) * | 2016-02-01 | 2018-10-26 | 复旦大学 | 一种铂类抗肿瘤前体药物，其纳米水凝胶药物及其制备方法 |
| CN107955042B (zh) * | 2017-11-23 | 2020-01-21 | 青岛大学附属医院 | 具有抗癌活性的铂类配合物、制备方法及应用 |
| US12351593B2 (en) | 2019-09-05 | 2025-07-08 | Vuab Pharma A.S. | Platinum IV complexes with substantially increased antitumor efficacy |
| CN112961190A (zh) * | 2021-02-07 | 2021-06-15 | 山东省第二人民医院(山东省耳鼻喉医院、山东省耳鼻喉研究所) | 一种藜芦酸四价铂及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8101026A (nl) * | 1981-03-03 | 1982-10-01 | Tno | Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel. |
| JPS6087295A (ja) * | 1983-10-19 | 1985-05-16 | Nippon Kayaku Co Ltd | 新規白金錯体 |
| JPS62207283A (ja) * | 1986-03-07 | 1987-09-11 | Yoshinori Kitani | 新規な白金錯体 |
-
1989
- 1989-01-27 EP EP89300787A patent/EP0328274B1/en not_active Expired - Lifetime
- 1989-01-27 AT AT89300787T patent/ATE113054T1/de not_active IP Right Cessation
- 1989-01-27 ES ES89300787T patent/ES2063119T3/es not_active Expired - Lifetime
- 1989-01-27 DE DE68918878T patent/DE68918878T2/de not_active Expired - Lifetime
- 1989-01-30 IL IL8911989A patent/IL89119A/en unknown
- 1989-01-31 KR KR1019890001069A patent/KR0147270B1/ko not_active Expired - Fee Related
- 1989-02-01 CA CA000589796A patent/CA1340286C/en not_active Expired - Lifetime
- 1989-02-01 AU AU28971/89A patent/AU618310B2/en not_active Expired
- 1989-02-01 IE IE31989A patent/IE65503B1/en not_active IP Right Cessation
- 1989-02-02 PT PT89608A patent/PT89608B/pt not_active IP Right Cessation
- 1989-02-02 FI FI890512A patent/FI91260C/fi not_active IP Right Cessation
- 1989-02-02 NO NO890426A patent/NO177569C/no not_active IP Right Cessation
- 1989-02-02 JP JP1024751A patent/JP2781403B2/ja not_active Expired - Lifetime
- 1989-02-02 NZ NZ227839A patent/NZ227839A/en unknown
- 1989-02-02 HU HU89522A patent/HU205767B/hu unknown
- 1989-02-02 DK DK198900491A patent/DK175050B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2063119T3 (es) | 1995-01-01 |
| ATE113054T1 (de) | 1994-11-15 |
| FI890512A0 (fi) | 1989-02-02 |
| DE68918878D1 (de) | 1994-11-24 |
| FI890512L (fi) | 1989-08-03 |
| JP2781403B2 (ja) | 1998-07-30 |
| DK49189D0 (da) | 1989-02-02 |
| FI91260C (fi) | 1994-06-10 |
| PT89608B (pt) | 1994-05-31 |
| DK49189A (da) | 1989-08-03 |
| NO890426L (no) | 1989-08-03 |
| IL89119A0 (en) | 1989-08-15 |
| EP0328274A1 (en) | 1989-08-16 |
| CA1340286C (en) | 1998-12-22 |
| JPH01294684A (ja) | 1989-11-28 |
| IE890319L (en) | 1989-08-02 |
| EP0328274B1 (en) | 1994-10-19 |
| KR0147270B1 (ko) | 1998-08-17 |
| HUT49890A (en) | 1989-11-28 |
| DE68918878T2 (de) | 1995-02-23 |
| AU618310B2 (en) | 1991-12-19 |
| FI91260B (fi) | 1994-02-28 |
| NO177569B (no) | 1995-07-03 |
| DK175050B1 (da) | 2004-05-10 |
| AU2897189A (en) | 1989-08-03 |
| PT89608A (pt) | 1989-10-04 |
| KR890013044A (ko) | 1989-09-21 |
| NO890426D0 (no) | 1989-02-02 |
| HU205767B (en) | 1992-06-29 |
| NO177569C (no) | 1995-10-11 |
| NZ227839A (en) | 1991-06-25 |
| IE65503B1 (en) | 1995-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |