CN107955042B - 具有抗癌活性的铂类配合物、制备方法及应用 - Google Patents
具有抗癌活性的铂类配合物、制备方法及应用 Download PDFInfo
- Publication number
- CN107955042B CN107955042B CN201711182952.XA CN201711182952A CN107955042B CN 107955042 B CN107955042 B CN 107955042B CN 201711182952 A CN201711182952 A CN 201711182952A CN 107955042 B CN107955042 B CN 107955042B
- Authority
- CN
- China
- Prior art keywords
- platinum
- platinum complex
- cancer
- preparation
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711182952.XA CN107955042B (zh) | 2017-11-23 | 2017-11-23 | 具有抗癌活性的铂类配合物、制备方法及应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711182952.XA CN107955042B (zh) | 2017-11-23 | 2017-11-23 | 具有抗癌活性的铂类配合物、制备方法及应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN107955042A CN107955042A (zh) | 2018-04-24 |
CN107955042B true CN107955042B (zh) | 2020-01-21 |
Family
ID=61961763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201711182952.XA Active CN107955042B (zh) | 2017-11-23 | 2017-11-23 | 具有抗癌活性的铂类配合物、制备方法及应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107955042B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111303211B (zh) * | 2018-12-12 | 2022-08-12 | 天津医科大学 | 一种褪黑素-铂(iv)配合物、其制备方法及应用 |
CN111973754A (zh) * | 2019-05-21 | 2020-11-24 | 杭州磐田生物技术有限公司 | 含药物纳米颗粒及其制备方法和应用 |
CN110950915B (zh) * | 2019-12-24 | 2022-07-22 | 玉林师范学院 | 一种新型大黄酸类-铂(iv)前体抗癌配合物及其合成方法与应用 |
CN113402565B (zh) * | 2021-06-16 | 2023-07-28 | 中国人民解放军空军军医大学 | 一类含有泊沙康唑的四价铂配合物、制备方法及其应用 |
CN114605475B (zh) * | 2022-02-18 | 2024-02-02 | 云南贵金属实验室有限公司 | 轴向含有3-溴丙酮酸配体的口服Pt(Ⅳ)抗癌前药 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0328274A1 (en) * | 1988-02-02 | 1989-08-16 | Johnson Matthey, Inc., | Pt (IV) complexes |
CN102603805A (zh) * | 2012-02-14 | 2012-07-25 | 昆明贵研药业有限公司 | 具有抗肿瘤活性的铂(ii)配合物及其制备方法 |
CN105622673A (zh) * | 2016-01-25 | 2016-06-01 | 南开大学 | 具有抗癌活性的糖基化四价铂类化合物、制备方法及应用 |
-
2017
- 2017-11-23 CN CN201711182952.XA patent/CN107955042B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0328274A1 (en) * | 1988-02-02 | 1989-08-16 | Johnson Matthey, Inc., | Pt (IV) complexes |
CN102603805A (zh) * | 2012-02-14 | 2012-07-25 | 昆明贵研药业有限公司 | 具有抗肿瘤活性的铂(ii)配合物及其制备方法 |
CN105622673A (zh) * | 2016-01-25 | 2016-06-01 | 南开大学 | 具有抗癌活性的糖基化四价铂类化合物、制备方法及应用 |
Also Published As
Publication number | Publication date |
---|---|
CN107955042A (zh) | 2018-04-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN107955042B (zh) | 具有抗癌活性的铂类配合物、制备方法及应用 | |
WO2017148193A1 (zh) | 一类含有生物活性基团的四价铂配合物及其制备方法 | |
CN110950914B (zh) | 一种铱配合物及其合成方法和应用 | |
CN111187303B (zh) | 高抗肿瘤活性白叶藤碱铂(ii)配合物及其合成方法和应用 | |
CN113072588B (zh) | 一类含有青蒿琥酯的四价铂配合物及其制备方法与应用 | |
CN108774269B (zh) | 新型靶向苯并咪唑类衍生物抗肿瘤铂(ii)和钌(ii)配合物及其制备方法与应用 | |
CN111116667B (zh) | 基于8-羟基喹啉衍生物和1-苯基吡唑铱二聚体构筑的铱配合物及其合成方法和应用 | |
CN107827934B (zh) | 具有抗癌活性的四价铂配合物、制备方法及应用 | |
CN111205311A (zh) | 新型高抗肿瘤活性白叶藤碱锌(ii)配合物及其合成方法和应用 | |
CN113402565B (zh) | 一类含有泊沙康唑的四价铂配合物、制备方法及其应用 | |
CN107501303B (zh) | 一种布洛芬与喹啉-8-甲醛席夫碱构筑的铜(ii)配合物及其合成方法和应用 | |
Hoefer et al. | Synthesis, characterization, cytotoxic activity, and 19F NMR spectroscopic investigations of (OC-6-33)-diacetato (ethane-1, 2-diamine) bis (3, 3, 3-trifluoropropanoato) platinum (IV) and its platinum (II) counterpart | |
CN110698512B (zh) | 以2-乙酰基吡啶缩氨基硫脲为配体的锡配合物及其合成方法 | |
CN108148080B (zh) | 金属有机金(iii)配合物及其合成方法和应用 | |
CN105440085A (zh) | 9-苯并噻蒽腙-钌(ii)配合物及其合成方法和应用 | |
CN112047980A (zh) | 一种以2-乙酰基吡啶缩氨基硫脲为配体的铑配合物及其合成方法 | |
US10988496B2 (en) | Platinum (IV) complex | |
CN103772435A (zh) | 洛铂的一种水溶性、稳定衍生物 | |
CN115385940B (zh) | 白叶藤碱锌(ii)配合物及其应用 | |
Liu et al. | Synthesis and cancer cell cytotoxicity of gold (III) tetraarylporphyrins with a C5-carboxylate substituent | |
CN115160347B (zh) | 糖基白叶藤锌(ii)配合物和应用 | |
CN109762016B (zh) | 一种具有抗肿瘤活性的炔基膦酸双芳基锡配合物及其应用 | |
CN117551136A (zh) | 4-苯基-2,6-双(2’-吡嗪基)吡啶双核铂配合物、合成方法和应用 | |
CN108822038B (zh) | 一种高活性的离子型比生群衍生物及其合成方法和应用 | |
CN116789684A (zh) | 8-羟基喹啉类抗癌锌(ii)配合物及其合成方法和应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Han Lichun Inventor after: Zhang Lijian Inventor after: Song Panai Inventor after: Jin Jiande Inventor before: Jin Jiande |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20191210 Address after: 266000 Shandong city of Qingdao province Jiangsu City Road No. 16 Applicant after: Affiliated Hospital of University Of Qingdao Address before: Room 627, Building A, Junyue Building, Jiaojiang District, Taizhou City, Zhejiang Province Applicant before: Taizhou Taijie Chemical Technology Co., Ltd. |
|
GR01 | Patent grant | ||
GR01 | Patent grant |