DK49189D0 - Pt(iv)-kompleks samt farmaceutisk middel indeholdende dette - Google Patents

Pt(iv)-kompleks samt farmaceutisk middel indeholdende dette

Info

Publication number
DK49189D0
DK49189D0 DK049189A DK49189A DK49189D0 DK 49189 D0 DK49189 D0 DK 49189D0 DK 049189 A DK049189 A DK 049189A DK 49189 A DK49189 A DK 49189A DK 49189 D0 DK49189 D0 DK 49189D0
Authority
DK
Denmark
Prior art keywords
complex
pharmaceutical composition
composition containing
alkyl
dicarboxylate
Prior art date
Application number
DK049189A
Other languages
English (en)
Other versions
DK49189A (da
DK175050B1 (da
Inventor
Michael J Abrams
Christen M Giandomenico
Barry A Murrer
Jean F Vollano
Original Assignee
Johnson Matthey Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson Matthey Inc filed Critical Johnson Matthey Inc
Publication of DK49189D0 publication Critical patent/DK49189D0/da
Publication of DK49189A publication Critical patent/DK49189A/da
Application granted granted Critical
Publication of DK175050B1 publication Critical patent/DK175050B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00Metallocenes
    • C07F17/02Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198900491A 1988-02-02 1989-02-02 Pt(IV)-kompleks samt farmaceutisk middel indeholdende dette DK175050B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15167488A 1988-02-02 1988-02-02
US15167488 1988-02-02
US29677689A 1989-01-13 1989-01-13
US29677689 1989-01-13

Publications (3)

Publication Number Publication Date
DK49189D0 true DK49189D0 (da) 1989-02-02
DK49189A DK49189A (da) 1989-08-03
DK175050B1 DK175050B1 (da) 2004-05-10

Family

ID=26848859

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900491A DK175050B1 (da) 1988-02-02 1989-02-02 Pt(IV)-kompleks samt farmaceutisk middel indeholdende dette

Country Status (16)

Country Link
EP (1) EP0328274B1 (da)
JP (1) JP2781403B2 (da)
KR (1) KR0147270B1 (da)
AT (1) ATE113054T1 (da)
AU (1) AU618310B2 (da)
CA (1) CA1340286C (da)
DE (1) DE68918878T2 (da)
DK (1) DK175050B1 (da)
ES (1) ES2063119T3 (da)
FI (1) FI91260C (da)
HU (1) HU205767B (da)
IE (1) IE65503B1 (da)
IL (1) IL89119A (da)
NO (1) NO177569C (da)
NZ (1) NZ227839A (da)
PT (1) PT89608B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI905018A0 (fi) * 1989-10-17 1990-10-12 Bristol Myers Squibb Co I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet.
US5196555A (en) * 1989-10-17 1993-03-23 Bristol-Myers Squibb Company Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds
IT1251115B (it) * 1991-07-26 1995-05-04 Mauro Esposito Complessi molecolari del platino ad attivita' antitumorale
US5624919A (en) * 1993-09-14 1997-04-29 The University Of Vermont And State Agricultural College Trans platinum (IV) complexes
US5648384A (en) * 1993-10-04 1997-07-15 Tanaka Kikinzoku Kogyo K.K. Anti-tumor platinum (IV) complex
GB9408218D0 (en) * 1994-04-26 1994-06-15 Johnson Matthey Plc Improvements in platinum complexes
GB9502799D0 (en) * 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
AU4842996A (en) * 1995-02-28 1996-09-18 Yoshinori Kidani Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same
KR100246722B1 (ko) * 1997-12-30 2000-04-01 박호군 경구용 백금 착화합물 항암제 및 그 제조방법
CZ288912B6 (cs) * 1998-05-27 2001-09-12 Lachema, A. S. Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
CN1296377C (zh) * 2003-06-11 2007-01-24 南京大学 含醚键羧酸根为配体的铂(ⅱ)配合物的制备
CA2535584A1 (en) 2003-08-13 2005-02-24 University Of South Florida Platinum complexes for the treatment of tumors
ATE346076T1 (de) * 2003-10-13 2006-12-15 Salama Zoser B Nat Rer Dr Verfahren zur herstellung von trans- oder cis- diammoniumdichlorodihydroxoplatin (iv)-salzen und derivaten und ihre verwendung zur herstellung von pharmazeutischen wirkstoffen
US20050288365A1 (en) 2004-01-06 2005-12-29 Heidi Kay Platinum complexes and methods for inhibiting tumor cell proliferation
US20060205810A1 (en) * 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations
CZ300590B6 (cs) * 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300424B6 (cs) * 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
WO2015009841A2 (en) 2013-07-16 2015-01-22 Blend Therapeutics Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof
JP6321291B2 (ja) 2014-09-03 2018-05-09 ブイユーエービー ファーマ エー.エス. 増加した抗腫瘍効果を有する白金(iv)錯体
CN107709286B (zh) 2015-06-24 2021-02-19 日本化药株式会社 新型铂(ⅳ)络合物
US10596191B2 (en) 2015-09-14 2020-03-24 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of hexa-coordinated platinum complex
CN105713046B (zh) * 2016-02-01 2018-10-26 复旦大学 一种铂类抗肿瘤前体药物,其纳米水凝胶药物及其制备方法
CN107955042B (zh) * 2017-11-23 2020-01-21 青岛大学附属医院 具有抗癌活性的铂类配合物、制备方法及应用
IL291110A (en) 2019-09-05 2022-07-01 Vuab Pharma A S New iv platinum complexes with significantly increased antitumor activity
CN112961190A (zh) * 2021-02-07 2021-06-15 山东省第二人民医院(山东省耳鼻喉医院、山东省耳鼻喉研究所) 一种藜芦酸四价铂及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
JPS62207283A (ja) * 1986-03-07 1987-09-11 Yoshinori Kitani 新規な白金錯体

Also Published As

Publication number Publication date
FI890512A0 (fi) 1989-02-02
FI91260C (fi) 1994-06-10
NZ227839A (en) 1991-06-25
DE68918878T2 (de) 1995-02-23
FI890512A (fi) 1989-08-03
DK49189A (da) 1989-08-03
PT89608B (pt) 1994-05-31
ATE113054T1 (de) 1994-11-15
ES2063119T3 (es) 1995-01-01
EP0328274B1 (en) 1994-10-19
EP0328274A1 (en) 1989-08-16
AU2897189A (en) 1989-08-03
NO890426D0 (no) 1989-02-02
HU205767B (en) 1992-06-29
IE890319L (en) 1989-08-02
IL89119A0 (en) 1989-08-15
NO177569B (no) 1995-07-03
AU618310B2 (en) 1991-12-19
CA1340286C (en) 1998-12-22
KR0147270B1 (ko) 1998-08-17
IE65503B1 (en) 1995-11-01
NO890426L (no) 1989-08-03
DE68918878D1 (de) 1994-11-24
FI91260B (fi) 1994-02-28
JP2781403B2 (ja) 1998-07-30
HUT49890A (en) 1989-11-28
JPH01294684A (ja) 1989-11-28
NO177569C (no) 1995-10-11
IL89119A (en) 1994-04-12
PT89608A (pt) 1989-10-04
KR890013044A (ko) 1989-09-21
DK175050B1 (da) 2004-05-10

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Legal Events

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PUP Patent expired