FI890512A - Menetelmä Pt(IV)-kompleksin valmistamiseksi - Google Patents
Menetelmä Pt(IV)-kompleksin valmistamiseksi Download PDFInfo
- Publication number
- FI890512A FI890512A FI890512A FI890512A FI890512A FI 890512 A FI890512 A FI 890512A FI 890512 A FI890512 A FI 890512A FI 890512 A FI890512 A FI 890512A FI 890512 A FI890512 A FI 890512A
- Authority
- FI
- Finland
- Prior art keywords
- complex
- preparing
- alkyl
- dicarboxylate
- alkylamino
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15167488A | 1988-02-02 | 1988-02-02 | |
US15167488 | 1988-02-02 | ||
US29677689A | 1989-01-13 | 1989-01-13 | |
US29677689 | 1989-01-13 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI890512A0 FI890512A0 (fi) | 1989-02-02 |
FI890512A true FI890512A (fi) | 1989-08-03 |
FI91260B FI91260B (fi) | 1994-02-28 |
FI91260C FI91260C (fi) | 1994-06-10 |
Family
ID=26848859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI890512A FI91260C (fi) | 1988-02-02 | 1989-02-02 | Menetelmä Pt(IV)-kompleksin valmistamiseksi |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0328274B1 (fi) |
JP (1) | JP2781403B2 (fi) |
KR (1) | KR0147270B1 (fi) |
AT (1) | ATE113054T1 (fi) |
AU (1) | AU618310B2 (fi) |
CA (1) | CA1340286C (fi) |
DE (1) | DE68918878T2 (fi) |
DK (1) | DK175050B1 (fi) |
ES (1) | ES2063119T3 (fi) |
FI (1) | FI91260C (fi) |
HU (1) | HU205767B (fi) |
IE (1) | IE65503B1 (fi) |
IL (1) | IL89119A (fi) |
NO (1) | NO177569C (fi) |
NZ (1) | NZ227839A (fi) |
PT (1) | PT89608B (fi) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI905018A0 (fi) * | 1989-10-17 | 1990-10-12 | Bristol Myers Squibb Co | I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet. |
US5196555A (en) * | 1989-10-17 | 1993-03-23 | Bristol-Myers Squibb Company | Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity |
GB9105037D0 (en) * | 1991-03-09 | 1991-04-24 | Johnson Matthey Plc | Improvements in chemical compounds |
IT1251115B (it) * | 1991-07-26 | 1995-05-04 | Mauro Esposito | Complessi molecolari del platino ad attivita' antitumorale |
US5624919A (en) * | 1993-09-14 | 1997-04-29 | The University Of Vermont And State Agricultural College | Trans platinum (IV) complexes |
EP0646589A3 (en) * | 1993-10-04 | 1995-06-28 | Tanaka Precious Metal Ind | Anti-tumor platinum (IV) complexes. |
GB9408218D0 (en) * | 1994-04-26 | 1994-06-15 | Johnson Matthey Plc | Improvements in platinum complexes |
GB9502799D0 (en) * | 1995-02-14 | 1995-04-05 | Johnson Matthey Plc | Improvements in platinum complexes |
DE69627641T2 (de) * | 1995-02-28 | 2004-02-05 | Kidani, Yoshinori, Fujisawa | Platin(iv)-komplexe, verfahren zu ihrer herstellung und sie enthaltende carcinostatische mittel |
KR100246722B1 (ko) * | 1997-12-30 | 2000-04-01 | 박호군 | 경구용 백금 착화합물 항암제 및 그 제조방법 |
CZ288912B6 (cs) * | 1998-05-27 | 2001-09-12 | Lachema, A. S. | Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující |
AU2003217676B2 (en) | 2002-02-22 | 2009-06-11 | Takeda Pharmaceutical Company Limited | Active agent delivery systems and methods for protecting and administering active agents |
CN1296377C (zh) * | 2003-06-11 | 2007-01-24 | 南京大学 | 含醚键羧酸根为配体的铂(ⅱ)配合物的制备 |
CA2535762A1 (en) | 2003-08-13 | 2005-03-17 | University Of South Florida | Methods for inhibiting tumor cell proliferation |
ATE346076T1 (de) * | 2003-10-13 | 2006-12-15 | Salama Zoser B Nat Rer Dr | Verfahren zur herstellung von trans- oder cis- diammoniumdichlorodihydroxoplatin (iv)-salzen und derivaten und ihre verwendung zur herstellung von pharmazeutischen wirkstoffen |
US20050288365A1 (en) | 2004-01-06 | 2005-12-29 | Heidi Kay | Platinum complexes and methods for inhibiting tumor cell proliferation |
US20060205810A1 (en) * | 2004-11-24 | 2006-09-14 | Schering Corporation | Platinum therapeutic combinations |
CZ300590B6 (cs) * | 2006-06-20 | 2009-06-24 | Pliva - Lachema A. S. | Farmaceutická kompozice pro injekcní podání |
CZ300424B6 (cs) * | 2006-06-20 | 2009-05-13 | Pliva - Lachema A. S. | Farmaceutická kompozice pro perorální podání |
WO2015009841A2 (en) * | 2013-07-16 | 2015-01-22 | Blend Therapeutics | Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof |
RU2666898C1 (ru) * | 2014-09-03 | 2018-09-13 | Вуаб Фарма А.С. | Комплексы платины (iv) с повышенной противораковой эффективностью |
EP3315487B1 (en) | 2015-06-24 | 2020-10-28 | Nippon Kayaku Kabushiki Kaisha | Novel platinum (iv) complex |
EP3351580B1 (en) | 2015-09-14 | 2021-02-24 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of hexa-coordinated platinum complex |
CN105713046B (zh) * | 2016-02-01 | 2018-10-26 | 复旦大学 | 一种铂类抗肿瘤前体药物,其纳米水凝胶药物及其制备方法 |
CN107955042B (zh) * | 2017-11-23 | 2020-01-21 | 青岛大学附属医院 | 具有抗癌活性的铂类配合物、制备方法及应用 |
WO2021043402A1 (en) | 2019-09-05 | 2021-03-11 | Vuab Pharma A.S. | New platinum iv complexes with substantially increased antitumor efficacy |
CN112961190A (zh) * | 2021-02-07 | 2021-06-15 | 山东省第二人民医院(山东省耳鼻喉医院、山东省耳鼻喉研究所) | 一种藜芦酸四价铂及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8101026A (nl) * | 1981-03-03 | 1982-10-01 | Tno | Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel. |
JPS6087295A (ja) * | 1983-10-19 | 1985-05-16 | Nippon Kayaku Co Ltd | 新規白金錯体 |
JPS62207283A (ja) * | 1986-03-07 | 1987-09-11 | Yoshinori Kitani | 新規な白金錯体 |
-
1989
- 1989-01-27 EP EP89300787A patent/EP0328274B1/en not_active Expired - Lifetime
- 1989-01-27 ES ES89300787T patent/ES2063119T3/es not_active Expired - Lifetime
- 1989-01-27 AT AT89300787T patent/ATE113054T1/de not_active IP Right Cessation
- 1989-01-27 DE DE68918878T patent/DE68918878T2/de not_active Expired - Lifetime
- 1989-01-30 IL IL8911989A patent/IL89119A/en unknown
- 1989-01-31 KR KR1019890001069A patent/KR0147270B1/ko not_active IP Right Cessation
- 1989-02-01 AU AU28971/89A patent/AU618310B2/en not_active Expired
- 1989-02-01 CA CA000589796A patent/CA1340286C/en not_active Expired - Lifetime
- 1989-02-01 IE IE31989A patent/IE65503B1/en not_active IP Right Cessation
- 1989-02-02 DK DK198900491A patent/DK175050B1/da not_active IP Right Cessation
- 1989-02-02 FI FI890512A patent/FI91260C/fi not_active IP Right Cessation
- 1989-02-02 NO NO890426A patent/NO177569C/no not_active IP Right Cessation
- 1989-02-02 PT PT89608A patent/PT89608B/pt not_active IP Right Cessation
- 1989-02-02 NZ NZ227839A patent/NZ227839A/en unknown
- 1989-02-02 HU HU89522A patent/HU205767B/hu unknown
- 1989-02-02 JP JP1024751A patent/JP2781403B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK49189A (da) | 1989-08-03 |
IL89119A0 (en) | 1989-08-15 |
HU205767B (en) | 1992-06-29 |
NZ227839A (en) | 1991-06-25 |
NO890426D0 (no) | 1989-02-02 |
NO890426L (no) | 1989-08-03 |
PT89608A (pt) | 1989-10-04 |
HUT49890A (en) | 1989-11-28 |
IE65503B1 (en) | 1995-11-01 |
AU2897189A (en) | 1989-08-03 |
ATE113054T1 (de) | 1994-11-15 |
DE68918878T2 (de) | 1995-02-23 |
DK49189D0 (da) | 1989-02-02 |
AU618310B2 (en) | 1991-12-19 |
DK175050B1 (da) | 2004-05-10 |
JP2781403B2 (ja) | 1998-07-30 |
JPH01294684A (ja) | 1989-11-28 |
KR0147270B1 (ko) | 1998-08-17 |
ES2063119T3 (es) | 1995-01-01 |
FI890512A0 (fi) | 1989-02-02 |
NO177569B (no) | 1995-07-03 |
FI91260C (fi) | 1994-06-10 |
IL89119A (en) | 1994-04-12 |
EP0328274A1 (en) | 1989-08-16 |
CA1340286C (en) | 1998-12-22 |
KR890013044A (ko) | 1989-09-21 |
DE68918878D1 (de) | 1994-11-24 |
IE890319L (en) | 1989-08-02 |
NO177569C (no) | 1995-10-11 |
EP0328274B1 (en) | 1994-10-19 |
FI91260B (fi) | 1994-02-28 |
PT89608B (pt) | 1994-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
FG | Patent granted |
Owner name: JOHNSON MATTHEY INC. |
|
MA | Patent expired |