ES8505996A1 - Procedimiento para la preparacion de derivados de sulfenamida - Google Patents

Procedimiento para la preparacion de derivados de sulfenamida

Info

Publication number
ES8505996A1
ES8505996A1 ES536305A ES536305A ES8505996A1 ES 8505996 A1 ES8505996 A1 ES 8505996A1 ES 536305 A ES536305 A ES 536305A ES 536305 A ES536305 A ES 536305A ES 8505996 A1 ES8505996 A1 ES 8505996A1
Authority
ES
Spain
Prior art keywords
compounds
preparation
medicaments containing
sulfenamide derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES536305A
Other languages
English (en)
Other versions
ES536305A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heumann Ludwig and Co GmbH
Original Assignee
Heumann Ludwig and Co GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Ludwig and Co GmbH filed Critical Heumann Ludwig and Co GmbH
Publication of ES8505996A1 publication Critical patent/ES8505996A1/es
Publication of ES536305A0 publication Critical patent/ES536305A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE DERIVADOS DE SULFENAMIDA, DE FORMULA (I), Y DE SUS SALES FARMACOLOGICAMENTE ACEPTABLES, DONDE R1 ES HIDROGENO; R2 ES ALQUILO C1-6 LINEAL O RAMIFICADO, CICLOALQUILO C5-6, ARILO O HETEROARILO, SUSTITUIDO O NO; O R1 Y R2 FORMAN UN ANILLO DE ISOTIAZOLINA O DE ISOTIAZOLINONA.MEDIANTE LA REACCION EN PRESENCIA DE UNA BASE DE UNA AMINA DE FORMULA (II) CON UN HALOGENURO DE SULFENILO R2-S-HAL DONDE HAL ES CLORO O BROMO; O POR REACCION ENTRE UN CLORURO DE SULFENILO Y UN ACIDO DE FORMULA (III).DE APLICACION POR SU EFECTO SELECTIVO SOBRE RECEPTORES-H2 DE HISTAMINA.
ES536305A 1983-10-06 1984-09-27 Procedimiento para la preparacion de derivados de sulfenamida Granted ES536305A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833336410 DE3336410A1 (de) 1983-10-06 1983-10-06 Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8505996A1 true ES8505996A1 (es) 1985-07-01
ES536305A0 ES536305A0 (es) 1985-07-01

Family

ID=6211186

Family Applications (1)

Application Number Title Priority Date Filing Date
ES536305A Granted ES536305A0 (es) 1983-10-06 1984-09-27 Procedimiento para la preparacion de derivados de sulfenamida

Country Status (14)

Country Link
EP (1) EP0141119A3 (es)
JP (1) JPS60100562A (es)
KR (1) KR850002974A (es)
AU (1) AU3268284A (es)
DE (1) DE3336410A1 (es)
DK (1) DK451784A (es)
ES (1) ES536305A0 (es)
GR (1) GR80476B (es)
HU (1) HUT35667A (es)
IL (1) IL72855A0 (es)
NZ (1) NZ209707A (es)
PT (1) PT79288A (es)
YU (1) YU168384A (es)
ZA (1) ZA846898B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193253B (en) * 1985-01-29 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 3,5-diamino-1,2,4-triazole derivatives
ATE451105T1 (de) * 2001-10-16 2009-12-15 Univ Kansas Neue prodrugs von n-h-bindung enthaltenden verbindungen und verfahren zu ihrer herstellung
CN103058958A (zh) * 2011-10-22 2013-04-24 杭州福斯特药业有限公司 一种罗沙替丁醋酸酯盐酸盐的合成方法
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
US4410523A (en) * 1979-10-22 1983-10-18 Glaxo Group Limited Heterocyclic derivatives
AU548426B2 (en) * 1980-08-27 1985-12-12 Glaxo Group Limited 3-amino-(1,2,4)-triazoles
ES520031A0 (es) * 1982-02-24 1984-04-01 Glaxo Group Ltd Un procedimiento para prepararacion de derivados del triazol.

Also Published As

Publication number Publication date
IL72855A0 (en) 1984-12-31
DE3336410A1 (de) 1985-04-18
DK451784A (da) 1985-04-07
NZ209707A (en) 1986-11-12
AU3268284A (en) 1985-05-02
HUT35667A (en) 1985-07-29
KR850002974A (ko) 1985-05-28
DK451784D0 (da) 1984-09-21
GR80476B (en) 1985-02-07
EP0141119A3 (de) 1988-02-03
EP0141119A2 (de) 1985-05-15
PT79288A (de) 1984-11-01
ES536305A0 (es) 1985-07-01
YU168384A (en) 1986-10-31
ZA846898B (en) 1985-04-24
JPS60100562A (ja) 1985-06-04

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