ES8303393A1 - Un procedimiento para preparar derivados del acido ascorbico. - Google Patents

Un procedimiento para preparar derivados del acido ascorbico.

Info

Publication number
ES8303393A1
ES8303393A1 ES510694A ES510694A ES8303393A1 ES 8303393 A1 ES8303393 A1 ES 8303393A1 ES 510694 A ES510694 A ES 510694A ES 510694 A ES510694 A ES 510694A ES 8303393 A1 ES8303393 A1 ES 8303393A1
Authority
ES
Spain
Prior art keywords
ascorbic acid
acid derivatives
general formula
same
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510694A
Other languages
English (en)
Other versions
ES510694A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of ES510694A0 publication Critical patent/ES510694A0/es
Publication of ES8303393A1 publication Critical patent/ES8303393A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO ASCORBICO Y DE SUS SALES, DE FORMULA (I), EN LA QUE R , R , R Y R SON HIDROGENO O PIVALOILO, NO SIENDO HIDROGENO AL MISMO TIEMPO TODOS LOS RADICALES. CONSISTE EN LA REACCION DE ACIDO L-ASCORBICO O ACIDO L-ASCORBICO PROTEGIDO CON GRUPOS TALES COMO ISOPROPILIDENO, CON DERIVADOS ACTIVOS DEL ACIDO PIVALICO, TALES COMO CLORURO DE PIVALOILO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE TAL COMO PIRIDINA, A UNA TEMPERATURA PROXIMA A LA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LAS CATARATAS.
ES510694A 1981-03-24 1982-03-23 Un procedimiento para preparar derivados del acido ascorbico. Expired ES8303393A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56043044A JPS57156479A (en) 1981-03-24 1981-03-24 Ascorbic acid derivative

Publications (2)

Publication Number Publication Date
ES510694A0 ES510694A0 (es) 1983-02-01
ES8303393A1 true ES8303393A1 (es) 1983-02-01

Family

ID=12652892

Family Applications (1)

Application Number Title Priority Date Filing Date
ES510694A Expired ES8303393A1 (es) 1981-03-24 1982-03-23 Un procedimiento para preparar derivados del acido ascorbico.

Country Status (7)

Country Link
EP (1) EP0074411B1 (es)
JP (1) JPS57156479A (es)
DE (1) DE3239721C2 (es)
ES (1) ES8303393A1 (es)
GB (1) GB2109382B (es)
IT (1) IT1150726B (es)
WO (1) WO1982003393A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552895A (en) * 1983-03-14 1985-11-12 Eli Lilly And Company Furo[3,2-b]furan-2-(3H)-ones
US4886815A (en) * 1984-06-20 1989-12-12 Schachar Ronald A Treatment and prevention of retinal edema with dopaminergic antagonists
US4886795A (en) * 1984-06-20 1989-12-12 Schachar Ronald A Treatment and prevention of retinal edema with dopaminergic antagonists
FR2580644B1 (fr) * 1985-04-23 1990-01-12 Kao Corp Derives de l'acide ascorbique
ZA852614B (en) * 1985-05-17 1986-10-09 Takeda Chemical Industries, Ltd. Ascorbic acid ethers and their production
JPH0813739B2 (ja) * 1986-12-03 1996-02-14 武田薬品工業株式会社 白内障治療剤
FR2715156B1 (fr) * 1994-01-20 1996-03-01 Oreal Mono-esters d'acide cinnamique ou de ses dérivés et de vitamine C, leur procédé de préparation et leur utilisation comme anti-oxydants dans des compositions cosmétiques, pharmaceutiques ou alimentaires.
EP3092220B1 (en) * 2013-09-25 2021-01-20 University of Florida Research Foundation, Inc. Vitamin c prodrugs and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4987655A (es) * 1972-12-27 1974-08-22
US4208434A (en) * 1978-07-11 1980-06-17 The Coca-Cola Company Color stable food containing anthocyanic pigments and bio-available vitamin C and process for its production

Also Published As

Publication number Publication date
EP0074411A4 (en) 1983-07-04
DE3239721C2 (de) 1986-02-27
JPS57156479A (en) 1982-09-27
ES510694A0 (es) 1983-02-01
JPH0243749B2 (es) 1990-10-01
EP0074411A1 (en) 1983-03-23
GB2109382B (en) 1985-07-24
DE3239721T1 (de) 1983-03-24
IT8220295A0 (it) 1982-03-19
GB2109382A (en) 1983-06-02
EP0074411B1 (en) 1986-05-28
IT1150726B (it) 1986-12-17
WO1982003393A1 (en) 1982-10-14

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