IL86456A - Tetrazole derivatives useful as intermediates for preparing antihypertensive compounds - Google Patents

Tetrazole derivatives useful as intermediates for preparing antihypertensive compounds

Info

Publication number
IL86456A
IL86456A IL86456A IL8645688A IL86456A IL 86456 A IL86456 A IL 86456A IL 86456 A IL86456 A IL 86456A IL 8645688 A IL8645688 A IL 8645688A IL 86456 A IL86456 A IL 86456A
Authority
IL
Israel
Prior art keywords
intermediates
derivatives useful
antihypertensive compounds
tetrazole derivatives
preparing antihypertensive
Prior art date
Application number
IL86456A
Other languages
English (en)
Other versions
IL86456A0 (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL86456A0 publication Critical patent/IL86456A0/xx
Publication of IL86456A publication Critical patent/IL86456A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2284—Compounds with one or more Sn-N linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
IL86456A 1987-05-22 1988-05-20 Tetrazole derivatives useful as intermediates for preparing antihypertensive compounds IL86456A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/053,198 US4820843A (en) 1987-05-22 1987-05-22 Tetrazole intermediates to antihypertensive compounds

Publications (2)

Publication Number Publication Date
IL86456A0 IL86456A0 (en) 1988-11-15
IL86456A true IL86456A (en) 1992-12-01

Family

ID=21982564

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86456A IL86456A (en) 1987-05-22 1988-05-20 Tetrazole derivatives useful as intermediates for preparing antihypertensive compounds

Country Status (20)

Country Link
US (1) US4820843A (xx)
EP (1) EP0291969B1 (xx)
JP (1) JPH0774207B2 (xx)
KR (1) KR960009571B1 (xx)
AT (1) ATE101603T1 (xx)
AU (1) AU603525B2 (xx)
CA (1) CA1340325C (xx)
DE (1) DE3887772T2 (xx)
DK (1) DK274788A (xx)
ES (1) ES2061552T3 (xx)
FI (1) FI93831C (xx)
HU (1) HU198698B (xx)
IE (1) IE63204B1 (xx)
IL (1) IL86456A (xx)
MY (1) MY101284A (xx)
NO (1) NO178189C (xx)
NZ (1) NZ224741A (xx)
PT (1) PT87552B (xx)
RU (1) RU2091376C1 (xx)
ZA (1) ZA883528B (xx)

Families Citing this family (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
EP0733366B1 (en) * 1988-01-07 1998-04-01 E.I. Du Pont De Nemours And Company Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
CA2016710A1 (en) * 1989-05-15 1990-11-15 Prasun K. Chakravarty Substituted benzimidazoles as angiotensin ii antagonists
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
SG50669A1 (en) * 1989-06-30 1998-07-20 Du Pont Fused-ring aryl subtituted imidazoles
CA2020073A1 (en) * 1989-07-03 1991-01-04 Eric E. Allen Substituted quinazolinones as angiotensin ii antagonists
ATE113281T1 (de) * 1989-08-02 1994-11-15 Takeda Chemical Industries Ltd Pyrazol-derivate, verfahren zu deren herstellung und anwendung.
PT94960A (pt) * 1989-08-11 1991-04-18 Ici Plc Processo para a preparacao de derivados de quinolina e de composicoes farmaceuticas que as contem
US5298518A (en) * 1989-09-29 1994-03-29 Eisai Co., Ltd. Biphenylmethane derivative and pharmacological use
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IE903911A1 (en) * 1989-11-20 1991-05-22 Ici Plc Diazine derivatives
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DK0443983T3 (da) * 1990-02-19 1996-03-18 Ciba Geigy Ag Acrylforbindelser
US5284661A (en) * 1990-02-22 1994-02-08 Takeda Chemical Industries, Ltd. Fused thiophene derivatives, their production and use
CA2037630C (en) * 1990-03-07 2001-07-03 Akira Morimoto Nitrogen-containing heterocylic compounds, their production and use
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
TW201738B (xx) * 1990-03-20 1993-03-11 Sanofi Co
FR2659967B1 (fr) * 1990-03-20 1992-07-24 Sanofi Sa Derives d'imidazolinone n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
FR2665702B1 (fr) * 1990-08-08 1994-02-25 Sanofi Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
EP0453210A3 (en) * 1990-04-19 1993-01-13 Imperial Chemical Industries Plc Pyridine derivatives
US5198439A (en) * 1990-04-19 1993-03-30 Imperial Chemical Industries Plc Angiotension II antagonizing pyridine derivatives
ZA912983B (en) 1990-04-27 1992-01-29 Takeda Chemical Industries Ltd Benzimidazole derivatives,their production and use
US5703110A (en) * 1990-04-27 1997-12-30 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
US6004989A (en) 1990-04-27 1999-12-21 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
CA2041763A1 (en) 1990-05-11 1991-11-12 Sheih-Shung T. Chen Microbial transformation process for antihypertensive products
AU653524B2 (en) * 1990-06-08 1994-10-06 Roussel-Uclaf New imidazole derivatives, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
FR2673943B1 (fr) * 1991-03-13 1994-02-18 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
FR2663027B1 (fr) * 1990-06-08 1994-12-02 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5137902A (en) * 1990-07-13 1992-08-11 E. I. Du Pont De Nemours And Company 4-alkylimidazole derivatives and anti-hypertensive use thereof
RU1836357C (ru) * 1990-07-23 1993-08-23 Др.Карл Томэ ГмбХ Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами
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WO1992004343A1 (en) * 1990-09-04 1992-03-19 Yamanouchi Pharmaceutical Co., Ltd. Novel tetrahydrobenzazole derivative
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US5374615A (en) * 1990-10-31 1994-12-20 E. R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted imidazole and benzimidazole derivatives
DE4036706A1 (de) * 1990-11-17 1992-05-21 Hoechst Ag Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
JP3214856B2 (ja) * 1990-12-14 2001-10-02 スミスクライン・ビーチャム・コーポレイション イミダゾリル−アルケン酸
CA2058198A1 (en) * 1991-01-04 1992-07-05 Adalbert Wagner Azole derivatives, process for their preparation, and their use
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process
US5153347A (en) * 1991-01-31 1992-10-06 E. R. Squibb & Sons, Inc. Phosphonate, phosphinate derivatives useful as antihypertensive agents
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GB9102803D0 (en) * 1991-02-11 1991-03-27 Ici Plc Pyridine compounds
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US5191086A (en) * 1991-03-19 1993-03-02 E.R. Squibb & Sons, Inc. Imidazole and benzimidazole derivatives
US5206235A (en) * 1991-03-20 1993-04-27 Merck & Co., Inc. Benzo-fused lactams that promote the release of growth hormone
US5177074A (en) 1991-03-26 1993-01-05 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
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US5190942A (en) * 1991-04-22 1993-03-02 E. R. Squibb & Sons, Inc. Benzoxazole and related heterocyclic substituted imidazole and benzimidazole derivatives
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IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd The heterocyclic compounds are converted into biphenyl groups, their production and the pharmaceutical compositions containing them
US5256695A (en) * 1991-07-24 1993-10-26 E. R. Squibb & Sons, Inc. Acyl amidine and acyl guanidine substituted biphenyl derivatives
US5177097A (en) * 1991-07-24 1993-01-05 E. R. Squibb & Sons, Inc. Acyl amidine and acyl, guanidine substituted biphenyl derivatives
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IL103020A (en) * 1991-09-10 1998-10-30 Tanabe Seiyaku Co History of acid 3) 1, '1 in biphenyl 4 Methyl (4,5,6,7 tetrahydro H3 imidazo] C 4,5 [pyridine 4 carboxylic acid, preparation and pharmaceutical preparations containing them
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
US5252753A (en) * 1991-11-01 1993-10-12 Ortho Pharmaceutical Corporation Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
JPH08500323A (ja) * 1991-11-18 1996-01-16 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー Ａ▲ｉｉ▼受容体アンタゴニストの合成のためのテトラゾリルフェニルボロン酸中間体
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US5308853A (en) * 1991-12-20 1994-05-03 Warner-Lambert Company Substituted-5-methylidene hydantoins with AT1 receptor antagonist properties
US5225408A (en) * 1991-12-20 1993-07-06 E. R. Squibb & Sons, Inc. Biphenyl oxadiazinone angiotensin II inhibitors
FR2685697B1 (fr) * 1991-12-30 1994-02-04 Synthelabo Nouveaux derives de 2-(tetrazol-5-yl)-(1,1'-biphenyle), leur preparation et leur utilisation comme intermediaires de synthese.
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KR960701023A (ko) * 1993-04-07 1996-02-24 도쿠시마 슈이치 피라졸 유도체(pyrazole derivatives)
US5438136A (en) * 1993-11-02 1995-08-01 Merck & Co., Inc. Benzo-fused macrocycles promote release of growth hormone
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CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids

Also Published As

Publication number Publication date
FI882390A (fi) 1988-11-23
FI882390A0 (fi) 1988-05-20
ATE101603T1 (de) 1994-03-15
IL86456A0 (en) 1988-11-15
EP0291969A3 (en) 1990-10-31
NZ224741A (en) 1990-12-21
EP0291969A2 (en) 1988-11-23
AU603525B2 (en) 1990-11-15
FI93831C (fi) 1995-06-12
NO178189C (no) 1996-02-07
ZA883528B (en) 1990-01-31
FI93831B (fi) 1995-02-28
CA1340325C (en) 1999-01-19
DK274788A (da) 1988-11-23
ES2061552T3 (es) 1994-12-16
NO178189B (no) 1995-10-30
DE3887772T2 (de) 1994-06-23
IE63204B1 (en) 1995-04-05
KR960009571B1 (ko) 1996-07-20
RU2091376C1 (ru) 1997-09-27
MY101284A (en) 1991-08-17
HUT47550A (en) 1989-03-28
EP0291969B1 (en) 1994-02-16
PT87552B (pt) 1992-09-30
NO882241D0 (no) 1988-05-20
IE881515L (en) 1988-11-22
AU1650388A (en) 1988-11-24
US4820843A (en) 1989-04-11
HU198698B (en) 1989-11-28
KR880013909A (ko) 1988-12-22
PT87552A (pt) 1989-05-31
NO882241L (no) 1988-11-23
JPH0774207B2 (ja) 1995-08-09
DE3887772D1 (de) 1994-03-24
DK274788D0 (da) 1988-05-19
JPH01117876A (ja) 1989-05-10

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