DK274788D0 - Tetrazoler - Google Patents

Tetrazoler

Info

Publication number
DK274788D0
DK274788D0 DK274788A DK274788A DK274788D0 DK 274788 D0 DK274788 D0 DK 274788D0 DK 274788 A DK274788 A DK 274788A DK 274788 A DK274788 A DK 274788A DK 274788 D0 DK274788 D0 DK 274788D0
Authority
DK
Denmark
Prior art keywords
tetrazoles
chem
ser
formula
filed july
Prior art date
Application number
DK274788A
Other languages
English (en)
Other versions
DK274788A (da
Inventor
Paul Edward Aldrich
John Jonas Vytautas Duncia
Michael Ernest Pierce
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of DK274788D0 publication Critical patent/DK274788D0/da
Publication of DK274788A publication Critical patent/DK274788A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2284—Compounds with one or more Sn-N linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
DK274788A 1987-05-22 1988-05-19 Tetrazoler DK274788A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/053,198 US4820843A (en) 1987-05-22 1987-05-22 Tetrazole intermediates to antihypertensive compounds

Publications (2)

Publication Number Publication Date
DK274788D0 true DK274788D0 (da) 1988-05-19
DK274788A DK274788A (da) 1988-11-23

Family

ID=21982564

Family Applications (1)

Application Number Title Priority Date Filing Date
DK274788A DK274788A (da) 1987-05-22 1988-05-19 Tetrazoler

Country Status (20)

Country Link
US (1) US4820843A (da)
EP (1) EP0291969B1 (da)
JP (1) JPH0774207B2 (da)
KR (1) KR960009571B1 (da)
AT (1) ATE101603T1 (da)
AU (1) AU603525B2 (da)
CA (1) CA1340325C (da)
DE (1) DE3887772T2 (da)
DK (1) DK274788A (da)
ES (1) ES2061552T3 (da)
FI (1) FI93831C (da)
HU (1) HU198698B (da)
IE (1) IE63204B1 (da)
IL (1) IL86456A (da)
MY (1) MY101284A (da)
NO (1) NO178189C (da)
NZ (1) NZ224741A (da)
PT (1) PT87552B (da)
RU (1) RU2091376C1 (da)
ZA (1) ZA883528B (da)

Families Citing this family (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0733366B1 (en) * 1988-01-07 1998-04-01 E.I. Du Pont De Nemours And Company Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
CA2016710A1 (en) * 1989-05-15 1990-11-15 Prasun K. Chakravarty Substituted benzimidazoles as angiotensin ii antagonists
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US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
WO1991000281A2 (en) 1989-06-30 1991-01-10 E.I. Du Pont De Nemours And Company Fused-ring aryl substituted imidazoles
CA2020073A1 (en) * 1989-07-03 1991-01-04 Eric E. Allen Substituted quinazolinones as angiotensin ii antagonists
ATE113281T1 (de) * 1989-08-02 1994-11-15 Takeda Chemical Industries Ltd Pyrazol-derivate, verfahren zu deren herstellung und anwendung.
PL286445A1 (en) * 1989-08-11 1991-04-22 Ici Plc Method of obtaining novel quinoline derivatives
US5298518A (en) * 1989-09-29 1994-03-29 Eisai Co., Ltd. Biphenylmethane derivative and pharmacological use
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IL95975A (en) * 1989-10-24 1997-06-10 Takeda Chemical Industries Ltd N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
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US5162326A (en) * 1990-02-15 1992-11-10 Takeda Chemical Industries, Ltd. Pyrimidinedione derivatives, their production and use
EP0443983B1 (de) * 1990-02-19 1996-02-28 Ciba-Geigy Ag Acylverbindungen
US5284661A (en) * 1990-02-22 1994-02-08 Takeda Chemical Industries, Ltd. Fused thiophene derivatives, their production and use
CA2037630C (en) * 1990-03-07 2001-07-03 Akira Morimoto Nitrogen-containing heterocylic compounds, their production and use
FR2659967B1 (fr) * 1990-03-20 1992-07-24 Sanofi Sa Derives d'imidazolinone n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
NZ237476A (en) * 1990-03-20 1994-01-26 Sanofi Sa N-substituted heterocyclic compounds and pharmaceutical compositions.
FR2665702B1 (fr) * 1990-08-08 1994-02-25 Sanofi Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
US5198439A (en) * 1990-04-19 1993-03-30 Imperial Chemical Industries Plc Angiotension II antagonizing pyridine derivatives
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
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US6004989A (en) 1990-04-27 1999-12-21 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
US5703110A (en) * 1990-04-27 1997-12-30 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
ZA912983B (en) 1990-04-27 1992-01-29 Takeda Chemical Industries Ltd Benzimidazole derivatives,their production and use
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
CA2041763A1 (en) 1990-05-11 1991-11-12 Sheih-Shung T. Chen Microbial transformation process for antihypertensive products
FR2663027B1 (fr) * 1990-06-08 1994-12-02 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
JPH04235974A (ja) * 1990-06-08 1992-08-25 Roussel Uclaf 新規なイミダゾール誘導体、それらの製造法、得られる新規な中間体、それらの薬剤としての使用及びそれらを含有する製薬組成物
FR2673943B1 (fr) * 1991-03-13 1994-02-18 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5137902A (en) * 1990-07-13 1992-08-11 E. I. Du Pont De Nemours And Company 4-alkylimidazole derivatives and anti-hypertensive use thereof
DE4023369A1 (de) * 1990-07-23 1992-01-30 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
RU1836357C (ru) * 1990-07-23 1993-08-23 Др.Карл Томэ ГмбХ Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами
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US5284954A (en) * 1990-09-10 1994-02-08 Abbott Laboratories Process for the preparation of tetrazoles
US5374615A (en) * 1990-10-31 1994-12-20 E. R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted imidazole and benzimidazole derivatives
DE4036706A1 (de) * 1990-11-17 1992-05-21 Hoechst Ag Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
AU9137791A (en) * 1990-12-14 1992-07-08 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
CA2058198A1 (en) * 1991-01-04 1992-07-05 Adalbert Wagner Azole derivatives, process for their preparation, and their use
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process
AT395853B (de) * 1991-01-31 1993-03-25 Chem Pharm Forsch Gmbh Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
US5153347A (en) * 1991-01-31 1992-10-06 E. R. Squibb & Sons, Inc. Phosphonate, phosphinate derivatives useful as antihypertensive agents
GB9102803D0 (en) * 1991-02-11 1991-03-27 Ici Plc Pyridine compounds
IE920175A1 (en) * 1991-02-11 1992-08-12 Zeneca Ltd Nitrogen heterocycles
US5472967A (en) * 1991-02-20 1995-12-05 Synthelabo 4-pyrimidinone derivatives their preparation and their application in therapy
US5616599A (en) * 1991-02-21 1997-04-01 Sankyo Company, Limited Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
US5191086A (en) * 1991-03-19 1993-03-02 E.R. Squibb & Sons, Inc. Imidazole and benzimidazole derivatives
EP0505098A1 (en) * 1991-03-19 1992-09-23 Merck & Co. Inc. Imidazole derivatives bearing acidic functional groups as angiotensin II antagonists
US5206235A (en) * 1991-03-20 1993-04-27 Merck & Co., Inc. Benzo-fused lactams that promote the release of growth hormone
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TW274551B (da) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
US5190942A (en) * 1991-04-22 1993-03-02 E. R. Squibb & Sons, Inc. Benzoxazole and related heterocyclic substituted imidazole and benzimidazole derivatives
US5506361A (en) * 1991-05-08 1996-04-09 Theupjohn Company Imidazobenzoquinones and composition for preventing or treating hypertension or congestive heart failure containing the same
US5210211A (en) * 1991-06-21 1993-05-11 Warner-Lambert Company 4-(1h-pyrrol-1-yl) imidazoles with angiotension ii antagonist activity
FR2677984B1 (fr) * 1991-06-21 1994-02-25 Elf Sanofi Derives d'imidazoline n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd The heterocyclic compounds are converted into biphenyl groups, their production and the pharmaceutical compositions containing them
US5256695A (en) * 1991-07-24 1993-10-26 E. R. Squibb & Sons, Inc. Acyl amidine and acyl guanidine substituted biphenyl derivatives
US5177097A (en) * 1991-07-24 1993-01-05 E. R. Squibb & Sons, Inc. Acyl amidine and acyl, guanidine substituted biphenyl derivatives
WO1993004046A1 (en) * 1991-08-19 1993-03-04 E.I. Du Pont De Nemours And Company Angiotensin ii receptor blocking imidazolinone derivatives
CZ36294A3 (en) * 1991-08-19 1994-07-13 Du Pont Substituted imidazilonone derivatives and pharmaceutical preparations based thereon
SG42942A1 (en) * 1991-09-10 1997-10-17 Tanabe Seiyaku Co Imidazopyridine derivatives and process for preparation thereof
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
US5252753A (en) * 1991-11-01 1993-10-12 Ortho Pharmaceutical Corporation Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
KR100212257B1 (ko) * 1991-11-18 1999-08-02 미리암 디. 메코나헤이 Aii 수용체 길항물질을 합성하기 위한 테트라졸릴페닐보론산 중간체의 제조 방법
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
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FR2685697B1 (fr) * 1991-12-30 1994-02-04 Synthelabo Nouveaux derives de 2-(tetrazol-5-yl)-(1,1'-biphenyle), leur preparation et leur utilisation comme intermediaires de synthese.
EP0550313A1 (fr) * 1991-12-30 1993-07-07 Synthelabo Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse
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US5208234A (en) * 1992-03-10 1993-05-04 E. R. Squibb & Sons, Inc. Substituted imidazole phosphonic and phosphinic acid derivatives
US5294722A (en) * 1992-04-16 1994-03-15 E. R. Squibb & Sons, Inc. Process for the preparation of imidazoles useful in angiotensin II antagonism
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US5283241A (en) * 1992-08-28 1994-02-01 Merck & Co., Inc. Benzo-fused lactams promote release of growth hormone
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RU2109736C1 (ru) * 1992-12-17 1998-04-27 Санкио Компани Лимитед Производные бифенила и способ их получения
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US5438136A (en) * 1993-11-02 1995-08-01 Merck & Co., Inc. Benzo-fused macrocycles promote release of growth hormone
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EP0711762B1 (en) 1994-05-16 2003-08-06 Sumitomo Chemical Company Limited Process for producing tetrazole compounds
JPH08325248A (ja) * 1995-05-26 1996-12-10 Chugoku Kayaku Kk テトラゾール類の新規な合成試薬及びそれを用いたテトラゾール類の製造方法
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Family Cites Families (5)

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JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
JPS5967246A (ja) * 1982-09-10 1984-04-16 ザ・ウエルカム・フアウンデ−シヨン・リミテツド 置換ビフエニル化合物
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ZA875052B (en) * 1986-07-11 1989-03-29 Du Pont Angiotensin ii receptor blocking imidazoles
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids

Also Published As

Publication number Publication date
IL86456A0 (en) 1988-11-15
AU603525B2 (en) 1990-11-15
PT87552A (pt) 1989-05-31
EP0291969A3 (en) 1990-10-31
IE63204B1 (en) 1995-04-05
US4820843A (en) 1989-04-11
ATE101603T1 (de) 1994-03-15
NZ224741A (en) 1990-12-21
FI882390A (fi) 1988-11-23
CA1340325C (en) 1999-01-19
KR880013909A (ko) 1988-12-22
NO178189B (no) 1995-10-30
AU1650388A (en) 1988-11-24
EP0291969B1 (en) 1994-02-16
DE3887772D1 (de) 1994-03-24
DE3887772T2 (de) 1994-06-23
FI93831C (fi) 1995-06-12
MY101284A (en) 1991-08-17
PT87552B (pt) 1992-09-30
NO178189C (no) 1996-02-07
IE881515L (en) 1988-11-22
FI93831B (fi) 1995-02-28
ES2061552T3 (es) 1994-12-16
JPH0774207B2 (ja) 1995-08-09
NO882241L (no) 1988-11-23
FI882390A0 (fi) 1988-05-20
HU198698B (en) 1989-11-28
EP0291969A2 (en) 1988-11-23
RU2091376C1 (ru) 1997-09-27
ZA883528B (en) 1990-01-31
HUT47550A (en) 1989-03-28
JPH01117876A (ja) 1989-05-10
KR960009571B1 (ko) 1996-07-20
IL86456A (en) 1992-12-01
NO882241D0 (no) 1988-05-20
DK274788A (da) 1988-11-23

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