ATE117294T1 - Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel. - Google Patents

Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.

Info

Publication number
ATE117294T1
ATE117294T1 AT90308855T AT90308855T ATE117294T1 AT E117294 T1 ATE117294 T1 AT E117294T1 AT 90308855 T AT90308855 T AT 90308855T AT 90308855 T AT90308855 T AT 90308855T AT E117294 T1 ATE117294 T1 AT E117294T1
Authority
AT
Austria
Prior art keywords
production
medicinal products
quinoline derivatives
quinoline
derivatives
Prior art date
Application number
AT90308855T
Other languages
English (en)
Inventor
David Anthony Roberts
Simon Thomas Russell
Robert James Pearce
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898918402A external-priority patent/GB8918402D0/en
Priority claimed from GB909003187A external-priority patent/GB9003187D0/en
Application filed by Ici Plc filed Critical Ici Plc
Application granted granted Critical
Publication of ATE117294T1 publication Critical patent/ATE117294T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
AT90308855T 1989-08-11 1990-08-10 Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel. ATE117294T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898918402A GB8918402D0 (en) 1989-08-11 1989-08-11 Nitrogen compounds
GB909003187A GB9003187D0 (en) 1990-02-13 1990-02-13 Nitrogen compounds

Publications (1)

Publication Number Publication Date
ATE117294T1 true ATE117294T1 (de) 1995-02-15

Family

ID=26295741

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90308855T ATE117294T1 (de) 1989-08-11 1990-08-10 Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.

Country Status (18)

Country Link
US (1) US5444071A (de)
EP (1) EP0412848B1 (de)
JP (1) JP3010056B2 (de)
KR (1) KR910004571A (de)
CN (1) CN1050187A (de)
AP (1) AP161A (de)
AT (1) ATE117294T1 (de)
AU (1) AU623546B2 (de)
BG (1) BG92674A (de)
DE (1) DE69016125T2 (de)
FI (1) FI903966A7 (de)
HU (1) HUT54991A (de)
IE (1) IE902909A1 (de)
NO (1) NO903525L (de)
NZ (1) NZ234854A (de)
PL (1) PL286445A1 (de)
PT (1) PT94960A (de)
YU (1) YU155290A (de)

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GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process
GB9017480D0 (en) * 1990-08-09 1990-09-26 Ici Plc Chemical process
GB9017479D0 (en) * 1990-08-09 1990-09-26 Ici Plc Process
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
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FR2680510B1 (fr) * 1991-08-20 1995-06-23 Roussel Uclaf Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US6004979A (en) * 1991-02-07 1999-12-21 Hoechst Marion Roussel Nitrogenous bicycles
FR2672596B1 (fr) * 1991-02-07 1995-07-13 Roussel Uclaf Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
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Also Published As

Publication number Publication date
JPH03169863A (ja) 1991-07-23
HUT54991A (en) 1991-04-29
EP0412848A3 (en) 1991-04-10
JP3010056B2 (ja) 2000-02-14
CN1050187A (zh) 1991-03-27
AU6095590A (en) 1991-02-14
AU623546B2 (en) 1992-05-14
DE69016125D1 (de) 1995-03-02
AP9000197A0 (en) 1990-10-31
PT94960A (pt) 1991-04-18
EP0412848B1 (de) 1995-01-18
NO903525L (no) 1991-02-12
KR910004571A (ko) 1991-03-28
FI903966A0 (fi) 1990-08-10
PL286445A1 (en) 1991-04-22
US5444071A (en) 1995-08-22
FI903966A7 (fi) 1991-02-12
NO903525D0 (no) 1990-08-10
EP0412848A2 (de) 1991-02-13
NZ234854A (en) 1993-02-25
AP161A (en) 1991-12-20
YU155290A (sh) 1993-05-28
BG92674A (bg) 1993-12-24
HU904961D0 (en) 1991-01-28
DE69016125T2 (de) 1995-06-01
IE902909A1 (en) 1991-02-27

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