NO903525L - Nitrogenforbindelser. - Google Patents

Nitrogenforbindelser.

Info

Publication number
NO903525L
NO903525L NO90903525A NO903525A NO903525L NO 903525 L NO903525 L NO 903525L NO 90903525 A NO90903525 A NO 90903525A NO 903525 A NO903525 A NO 903525A NO 903525 L NO903525 L NO 903525L
Authority
NO
Norway
Prior art keywords
nitrogen compounds
nitrogen
compounds
Prior art date
Application number
NO90903525A
Other languages
English (en)
Other versions
NO903525D0 (no
Inventor
David Anthony Roberts
Simon Thomas Russell
Robert James Pearce
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898918402A external-priority patent/GB8918402D0/en
Priority claimed from GB909003187A external-priority patent/GB9003187D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of NO903525D0 publication Critical patent/NO903525D0/no
Publication of NO903525L publication Critical patent/NO903525L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
NO90903525A 1989-08-11 1990-08-10 Nitrogenforbindelser. NO903525L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898918402A GB8918402D0 (en) 1989-08-11 1989-08-11 Nitrogen compounds
GB909003187A GB9003187D0 (en) 1990-02-13 1990-02-13 Nitrogen compounds

Publications (2)

Publication Number Publication Date
NO903525D0 NO903525D0 (no) 1990-08-10
NO903525L true NO903525L (no) 1991-02-12

Family

ID=26295741

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90903525A NO903525L (no) 1989-08-11 1990-08-10 Nitrogenforbindelser.

Country Status (17)

Country Link
US (1) US5444071A (no)
EP (1) EP0412848B1 (no)
JP (1) JP3010056B2 (no)
KR (1) KR910004571A (no)
CN (1) CN1050187A (no)
AP (1) AP161A (no)
AT (1) ATE117294T1 (no)
AU (1) AU623546B2 (no)
DE (1) DE69016125T2 (no)
FI (1) FI903966A0 (no)
HU (1) HUT54991A (no)
IE (1) IE902909A1 (no)
NO (1) NO903525L (no)
NZ (1) NZ234854A (no)
PL (1) PL286445A1 (no)
PT (1) PT94960A (no)
YU (1) YU155290A (no)

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GB9010394D0 (en) * 1990-05-09 1990-06-27 Ici Plc Heterocyclic compounds
GB9017479D0 (en) * 1990-08-09 1990-09-26 Ici Plc Process
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process
GB9017480D0 (en) * 1990-08-09 1990-09-26 Ici Plc Chemical process
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
IE914573A1 (en) * 1991-01-17 1992-07-29 Ici Plc Boron compounds
IE914572A1 (en) * 1991-01-17 1992-07-29 Zeneca Ltd Chemical process
MX9200299A (es) * 1991-02-07 1992-12-01 Roussel Uclaf Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
FR2680510B1 (fr) * 1991-08-20 1995-06-23 Roussel Uclaf Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US6004979A (en) * 1991-02-07 1999-12-21 Hoechst Marion Roussel Nitrogenous bicycles
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GB9102727D0 (en) * 1991-02-08 1991-03-27 Ici Plc Pharmaceutical agent
GB9102803D0 (en) * 1991-02-11 1991-03-27 Ici Plc Pyridine compounds
GB9102804D0 (en) * 1991-02-11 1991-03-27 Ici Plc Heterocyclic derivatives
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US5177074A (en) 1991-03-26 1993-01-05 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
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GB9113626D0 (en) * 1991-06-25 1991-08-14 Ici Plc Heterocyclic compounds
GB9113628D0 (en) * 1991-06-25 1991-08-14 Ici Plc Heterocyclic derivatives
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US5149699A (en) * 1991-10-24 1992-09-22 American Home Products Corporation Substituted pyridopyrimidines useful as antgiotensin II antagonists
GB9202633D0 (en) * 1992-02-07 1992-03-25 Fujisawa Pharmaceutical Co Heterocyclic derivatives
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US5616591A (en) * 1992-03-27 1997-04-01 E.R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted quinoline derivatives
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US5378704A (en) * 1992-04-15 1995-01-03 E. R. Squibb & Sons, Inc. Non-peptidic angiotensin-II-receptor-antagonists
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US5236916A (en) * 1992-05-26 1993-08-17 E. R. Squibb & Sons, Inc. Oxadiazinone substituted indole and benzimidazole derivatives
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US5571813A (en) * 1993-06-10 1996-11-05 Beiersdorf-Lilly Gmbh Fused pyrimidine compounds and their use as pharmaceuticals
US6080757A (en) * 1996-06-06 2000-06-27 Pfizer Inc Antibiotic quinolones and derivatives
TW418204B (en) * 1997-03-28 2001-01-11 Dev Center Biotechnology Novel 1,2,4-triazine-5-ketonyl benzene derivatives and the analogs, the preparation, and the pharmaceutical compositions as angiotension II receptor antogonists
US6638937B2 (en) 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
US6608048B2 (en) 2000-03-28 2003-08-19 Wyeth Holdings Tricyclic protein kinase inhibitors
AU2002341921B2 (en) * 2001-10-04 2007-05-31 Merck Sharp & Dohme Corp. Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5
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BRPI0701664A2 (pt) * 2007-05-28 2009-01-13 Fundacao Universidade Fed De Sco Carlos 4-quinolinonas e quinolinas, processo de preparaÇço, formulaÇÕes farmacÊuticas e uso das mesmas
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EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
JP5830534B2 (ja) 2010-07-09 2015-12-09 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 化合物
JP2013531030A (ja) 2010-07-12 2013-08-01 ファイザー・リミテッド 電位開口型ナトリウムチャネルの阻害剤としてのｎ−スルホニルベンズアミド
EP2593428B1 (en) 2010-07-12 2014-11-19 Pfizer Limited N-sulfonylbenzamides as inhibitors of voltage-gated sodium channels
ES2525581T3 (es) 2010-07-12 2014-12-26 Pfizer Limited Derivados de N-sulfonilbenzamida útiles como inhibidores del canal de sodio dependiente de voltaje
ES2532357T3 (es) 2010-07-12 2015-03-26 Pfizer Limited Derivados de sulfonamida como inhibidores de Nav1.7 para el tratamiento del dolor
WO2012007877A2 (en) 2010-07-12 2012-01-19 Pfizer Limited Chemical compounds
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
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US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
LT3325623T (lt) 2015-07-23 2019-10-25 Inst Curie Dbait molekulės ir parp inhibitorių derinio panaudojimas vėžiui gydyti
CN105330541B (zh) * 2015-11-03 2017-09-12 常州博世伟业生物科技有限公司 4’‑卤代甲基联苯‑2‑甲酸烷基酯的合成方法
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WO2018162439A1 (en) 2017-03-08 2018-09-13 Onxeo New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule
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Also Published As

Publication number Publication date
CN1050187A (zh) 1991-03-27
FI903966A0 (fi) 1990-08-10
HUT54991A (en) 1991-04-29
US5444071A (en) 1995-08-22
AP161A (en) 1991-12-20
HU904961D0 (en) 1991-01-28
PT94960A (pt) 1991-04-18
DE69016125D1 (de) 1995-03-02
DE69016125T2 (de) 1995-06-01
AP9000197A0 (en) 1990-10-31
ATE117294T1 (de) 1995-02-15
AU6095590A (en) 1991-02-14
EP0412848A2 (en) 1991-02-13
EP0412848A3 (en) 1991-04-10
IE902909A1 (en) 1991-02-27
JP3010056B2 (ja) 2000-02-14
NZ234854A (en) 1993-02-25
AU623546B2 (en) 1992-05-14
EP0412848B1 (en) 1995-01-18
YU155290A (sh) 1993-05-28
JPH03169863A (ja) 1991-07-23
PL286445A1 (en) 1991-04-22
KR910004571A (ko) 1991-03-28
NO903525D0 (no) 1990-08-10

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