IL85671A - A multi-part differential computing device that uses light scattering methods - Google Patents
A multi-part differential computing device that uses light scattering methodsInfo
- Publication number
- IL85671A IL85671A IL8567188A IL8567188A IL85671A IL 85671 A IL85671 A IL 85671A IL 8567188 A IL8567188 A IL 8567188A IL 8567188 A IL8567188 A IL 8567188A IL 85671 A IL85671 A IL 85671A
- Authority
- IL
- Israel
- Prior art keywords
- light
- signal
- cell
- lymphocytes
- differentiating
- Prior art date
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/016—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1024—Counting particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N2015/139—Measuring the ratio of AC/DC impedances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
- G01N2021/4711—Multiangle measurement
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2544287A | 1987-03-13 | 1987-03-13 | |
| US12995487A | 1987-12-04 | 1987-12-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL85671A0 IL85671A0 (en) | 1988-08-31 |
| IL85671A true IL85671A (en) | 1995-12-31 |
Family
ID=26699741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL8567188A IL85671A (en) | 1987-03-13 | 1988-03-08 | A multi-part differential computing device that uses light scattering methods |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5125737A (de) |
| EP (1) | EP0311655B1 (de) |
| JP (1) | JP2505873B2 (de) |
| KR (1) | KR970007077B1 (de) |
| CN (1) | CN1014742B (de) |
| AU (2) | AU602207B2 (de) |
| CA (1) | CA1315125C (de) |
| DE (1) | DE3852270T2 (de) |
| ES (1) | ES2009188A6 (de) |
| IL (1) | IL85671A (de) |
| WO (1) | WO1988007198A1 (de) |
Families Citing this family (160)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE195550T1 (de) * | 1990-11-23 | 2000-09-15 | Coulter Corp | Verfahren und vorrichtung zur reihensichtung mikroskopischer zellen unter verwendung von lichtstreuenden techniken |
| US5247188A (en) * | 1992-01-23 | 1993-09-21 | High Yield Technology | Concentrator funnel for vacuum line particle monitors |
| US6509192B1 (en) * | 1992-02-24 | 2003-01-21 | Coulter International Corp. | Quality control method |
| US5371585A (en) * | 1992-11-10 | 1994-12-06 | Pacific Scientific Company | Particle detecting instrument with sapphire detecting cell defining a rectangular flow path |
| ES2284160T3 (es) * | 1993-02-25 | 2007-11-01 | Abbott Laboratories | Sistema reactivo multiuso capaz de lisar rapidamente muestras de sangre completa. |
| US5534999A (en) * | 1993-03-05 | 1996-07-09 | Shinmikuni Kikai Ltd. | Monitoring sub-micron particles |
| ATE236397T1 (de) * | 1993-05-14 | 2003-04-15 | Coulter Int Corp | Retikulozyt bestimmungsverfahren und geraet, das lichtstreuungstechniken verwendet |
| US5576185A (en) | 1994-04-15 | 1996-11-19 | Coulter Corporation | Method of positive or negative selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation |
| JP3355038B2 (ja) * | 1994-08-03 | 2002-12-09 | シスメックス株式会社 | 白血球分類方法 |
| JP3375203B2 (ja) | 1994-08-08 | 2003-02-10 | シスメックス株式会社 | 細胞分析装置 |
| US5559037A (en) * | 1994-12-15 | 1996-09-24 | Abbott Laboratories | Method for rapid and simultaneous analysis of nucleated red blood cells |
| US5879900A (en) * | 1994-12-15 | 1999-03-09 | Abbott Laboratories | Method for simultaneous analysis of cell viability, nucleated red blood cells and white blood cell differentials |
| US5843608A (en) * | 1995-06-08 | 1998-12-01 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
| US5686308A (en) * | 1995-06-08 | 1997-11-11 | Coulter Corporation | Reagent and method for differential determination of leukocytes in blood |
| US5882933A (en) * | 1995-06-08 | 1999-03-16 | Coulter International Corp. | Method for determination of leukocytes and hemoglobin concentration in blood |
| US5786224A (en) * | 1995-06-29 | 1998-07-28 | Coulter Corporation | Reagent and method for differential determination of leukocytes in blood |
| US5817518A (en) * | 1995-12-18 | 1998-10-06 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
| US5686309A (en) * | 1996-01-19 | 1997-11-11 | Coulter International Corp. | Method and apparatus for determination of hemoglobin content of individual red blood cells |
| JP4136017B2 (ja) * | 1996-09-19 | 2008-08-20 | シスメックス株式会社 | 粒子分析装置 |
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| US5945293A (en) * | 1997-10-09 | 1999-08-31 | Coulter International Corp. | Protein-colloidal metal-aminodextran coated particle and methods of preparation and use |
| US5874311A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of reticulocytes in blood |
| US5874310A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
| US5917584A (en) * | 1997-11-21 | 1999-06-29 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| AU754999B2 (en) * | 1998-03-10 | 2002-11-28 | Large Scale Proteomics Corporation | Detection and characterization of microorganisms |
| FR2779296B1 (fr) * | 1998-06-02 | 2000-08-18 | France Telecom | Dispositif pour l'emission ou la reception d'un signal crypte par chaos deterministe |
| JP4101994B2 (ja) * | 1999-01-21 | 2008-06-18 | シスメックス株式会社 | 粒子分析装置および自動粒子分析方法 |
| US6228652B1 (en) | 1999-02-16 | 2001-05-08 | Coulter International Corp. | Method and apparatus for analyzing cells in a whole blood sample |
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| US6507400B1 (en) | 1999-02-27 | 2003-01-14 | Mwi, Inc. | Optical system for multi-part differential particle discrimination and an apparatus using the same |
| JP3817091B2 (ja) * | 1999-07-02 | 2006-08-30 | テルモ株式会社 | 細胞数測定装置 |
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| JP4708605B2 (ja) * | 2000-07-24 | 2011-06-22 | シスメックス株式会社 | 粒子分析装置とその粒子分画方法 |
| US8354647B2 (en) * | 2000-11-08 | 2013-01-15 | University Of North Florida | Photoelectric chemical sensor and sensing method utilizing interfacial photo-voltages |
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| US8634072B2 (en) * | 2004-03-06 | 2014-01-21 | Michael Trainer | Methods and apparatus for determining characteristics of particles |
| US10620105B2 (en) * | 2004-03-06 | 2020-04-14 | Michael Trainer | Methods and apparatus for determining characteristics of particles from scattered light |
| US9297737B2 (en) * | 2004-03-06 | 2016-03-29 | Michael Trainer | Methods and apparatus for determining characteristics of particles |
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| US7674598B2 (en) * | 2004-05-21 | 2010-03-09 | Beckman Coulter, Inc. | Method for a fully automated monoclonal antibody-based extended differential |
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-
1988
- 1988-03-04 KR KR1019880701385A patent/KR970007077B1/ko not_active IP Right Cessation
- 1988-03-08 IL IL8567188A patent/IL85671A/en not_active IP Right Cessation
- 1988-03-11 ES ES8800748A patent/ES2009188A6/es not_active Expired
- 1988-03-11 CA CA000561233A patent/CA1315125C/en not_active Expired - Fee Related
- 1988-03-12 CN CN88101232A patent/CN1014742B/zh not_active Expired
- 1988-03-14 DE DE3852270T patent/DE3852270T2/de not_active Expired - Lifetime
- 1988-03-14 EP EP88903074A patent/EP0311655B1/de not_active Expired - Lifetime
- 1988-03-14 AU AU14970/88A patent/AU602207B2/en not_active Expired
- 1988-03-14 JP JP63502800A patent/JP2505873B2/ja not_active Expired - Lifetime
- 1988-03-14 WO PCT/US1988/000753 patent/WO1988007198A1/en active IP Right Grant
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1990
- 1990-02-13 US US07/479,199 patent/US5125737A/en not_active Expired - Lifetime
- 1990-12-21 AU AU68483/90A patent/AU632393B2/en not_active Expired
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| EP0311655A4 (en) | 1990-09-05 |
| EP0311655B1 (de) | 1994-11-30 |
| WO1988007198A1 (en) | 1988-09-22 |
| CN1031422A (zh) | 1989-03-01 |
| KR970007077B1 (ko) | 1997-05-02 |
| DE3852270D1 (de) | 1995-01-12 |
| JPH01502533A (ja) | 1989-08-31 |
| ES2009188A6 (es) | 1989-09-01 |
| CA1315125C (en) | 1993-03-30 |
| US5125737A (en) | 1992-06-30 |
| CN1014742B (zh) | 1991-11-13 |
| AU602207B2 (en) | 1990-10-04 |
| AU6848390A (en) | 1991-03-14 |
| IL85671A0 (en) | 1988-08-31 |
| DE3852270T2 (de) | 1995-04-06 |
| JP2505873B2 (ja) | 1996-06-12 |
| AU632393B2 (en) | 1992-12-24 |
| KR890700829A (ko) | 1989-04-27 |
| AU1497088A (en) | 1988-10-10 |
| EP0311655A1 (de) | 1989-04-19 |
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